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Philosophical transactions. Biological sciences, ISSN 1471-2970, 12/2012, Volume 367, Issue 1607, pp. 3353 - 3363
Human tissues express cannabinoid CB₁ and CB₂ receptors that can be activated by endogenously released 'endocannabinoids' or exogenously administered compounds... 
Receptors | Cannabinoids | Animal models | Pain | Medical treatment | Agonists | Morphine | Drug design | Endocannabinoids | Cannabinoid receptors | health and disease and epidemiology | Articles | And CB2 | Blood-brain barrier | Cannabinoid receptor agonists | Δ9-tetrahydrocannabinol | Cannabinoid CB1 | Therapeutic applications and strategies | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Endocannabinoids - metabolism | Analgesics - pharmacology | Receptor, Cannabinoid, CB2 - agonists | Cardiovascular Diseases - drug therapy | Humans | Cannabinoid Receptor Agonists - pharmacology | Neurodegenerative Diseases - drug therapy | Pain - metabolism | Receptor, Cannabinoid, CB1 - agonists | Pain - drug therapy | Cannabinoid Receptor Agonists - therapeutic use | Dronabinol - pharmacology | Analgesics - therapeutic use | Cardiovascular Diseases - metabolism | Risk Assessment | Analgesics - administration & dosage | Clinical Trials as Topic | Neurodegenerative Diseases - metabolism | Blood-Brain Barrier - drug effects | Cannabinoid Receptor Agonists - administration & dosage | Drug Discovery | Blood-Brain Barrier - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Dronabinol - therapeutic use | Index Medicus | cannabinoid receptor agonists | blood-brain barrier | Review | cannabinoid CB1 and CB2 receptors | therapeutic applications and strategies
Journal Article
Journal Article
British journal of pharmacology, ISSN 0007-1188, 02/1999, Volume 126, Issue 3, pp. 665 - 672
Journal Article
BMC cancer, ISSN 1471-2407, 05/2018, Volume 18, Issue 1, pp. 583 - 583
.... In view of their further use for potential treatments, we thus investigated the roles of CB1 and CB2 receptors in the anti-proliferative action and signal transduction triggered by synthetic cannabinoid agonists... 
JWH-133 | and CB | Endocannabinoid system (ECS) | receptors | Renal cell carcinoma | WIN 55,212-2 mesylate | Life Sciences & Biomedicine | Oncology | Science & Technology | Proteins | Growth | Analysis | Genes | Cell cycle | Cellular signal transduction | Carcinoma, Renal cell | Research | Cytochemistry | Gene expression | Index Medicus | WIN 55,212–2 mesylate | CB1 and CB2 receptors
Journal Article
PloS one, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0132487 - e0132487
Recent studies have indicated that type 2 cannabinoid receptor (CB2R) agonists reduce neurodegeneration after brain injury through anti-inflammatory activity... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neurons - pathology | Receptor, Cannabinoid, CB2 - agonists | Brain Ischemia - genetics | Cerebral Cortex - pathology | Stroke - complications | Male | Cannabinoid Receptor Agonists - pharmacology | RNA, Messenger - metabolism | Receptor, Cannabinoid, CB2 - genetics | Nerve Degeneration - chemically induced | Neuroprotection - drug effects | Stroke - genetics | Behavior, Animal | Thiazolidinediones - therapeutic use | Time Factors | Cannabinoid Receptor Agonists - therapeutic use | Microfilament Proteins - metabolism | Neurons - metabolism | Neurons - drug effects | Thiazolidinediones - pharmacology | Microfilament Proteins - genetics | Brain Ischemia - complications | Calcium-Binding Proteins - metabolism | RNA, Messenger - genetics | Toll-Like Receptor 4 - genetics | Stroke - drug therapy | Nerve Degeneration - complications | Rats, Sprague-Dawley | Toll-Like Receptor 4 - metabolism | Cannabinoids - pharmacology | Glutamic Acid | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Cannabinoids - therapeutic use | Animals | Receptor, Cannabinoid, CB1 - genetics | Nerve Degeneration - drug therapy | Calcium-Binding Proteins - genetics | Stroke (Disease) | Brain | Inflammation | RNA | Injuries | Occlusion | Drug abuse | Neuroprotection | Neurosciences | Substance abuse treatment | Time dependence | Head injuries | Ischemia | Neurodegeneration | Cerebral blood flow | Rodents | Surgery | Toll-like receptors | Cannabinoid CB2 receptors | Pretreatment | Cerebral infarction | Medical research | Stroke | Pioglitazone | Rats | TLR4 protein | Gene expression | Anti-inflammatory agents | Neurological diseases | Injury prevention | Brain research | Animal behavior | Infarction | Peroxisome proliferator-activated receptors | Laboratory animals | Brain injury | Veins & arteries | Index Medicus
Journal Article
ACS chemical neuroscience, ISSN 1948-7193, 07/2015, Volume 6, Issue 9, pp. 1546 - 1559
.... All synthesized SCs acted as high potency agonists of CB1 (EC50 = 0.24–21 nM) and CB2 (EC50 = 0.88–15 nM) receptors in a fluorometric assay of membrane potential... 
FUBINACA | JWH-018 | Cannabinoid | PINACA | THC | Biochemistry & Molecular Biology | Neurosciences | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Neurosciences & Neurology | Chemistry, Medicinal | Science & Technology | Rats, Wistar | Receptor, Cannabinoid, CB2 - agonists | Body Temperature - drug effects | Indazoles - chemical synthesis | Humans | Indoles - chemical synthesis | Male | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Cannabinoid Receptor Agonists - chemistry | Cannabinoid Receptor Agonists - pharmacology | Receptor, Cannabinoid, CB2 - genetics | Dose-Response Relationship, Drug | Heart Rate - drug effects | Receptor, Cannabinoid, CB1 - agonists | Cannabinoid Receptor Antagonists - pharmacology | Indoles - pharmacology | Molecular Structure | Drug Evaluation, Preclinical | Membrane Potentials - drug effects | Designer Drugs - pharmacology | Indazoles - chemistry | Cannabinoid Receptor Agonists - chemical synthesis | Designer Drugs - chemical synthesis | Indazoles - pharmacology | Designer Drugs - chemistry | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Receptor, Cannabinoid, CB1 - genetics | Cell Line, Tumor | Mice | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Indoles - chemistry | Cohort Studies | Index Medicus
Journal Article
Molecular pharmacology, ISSN 0026-895X, 02/2018, Volume 93, Issue 2, pp. 49 - 62
The CB2 cannabinoid agonist LY2828360 lacked both toxicity and efficacy in a clinical trial for osteoarthritis... 
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Index Medicus
Journal Article