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Journal Article
PLoS Genetics, ISSN 1553-7390, 2015, Volume 11, Issue 12, pp. e1005694 - e1005694
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2013, Volume 45, Issue 2, pp. 197 - 201
Journal Article
06/2013
Background: Polycystic ovary syndrome (PCOS) is a complex disease having both genetic and environmental components and candidate genes on obesity and insulin... 
Polycystic ovary syndrome | Insulin/ genetics | Genetic/ genetics | Receptor | Adiponectin/ genetics | Polymorphism
Web Resource
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2007, Volume 104, Issue 38, pp. 15040 - 15044
We report 10 heterozygous mutations in the human insulin gene in 16 probands with neonatal diabetes. A combination of linkage and a candidate gene approach in... 
Molecules | Medical genetics | Disulfides | Diabetes | Type 2 diabetes mellitus | Genetic mutation | Insulin | Chromosomes | Human genetics | Type 1 diabetes mellitus | Disulfide bonds | Insulin biosynthesis | Endoplasmic reticulum stress | Unfolded protein response | KIR6.2 | B-CHAIN | MULTIDISCIPLINARY SCIENCES | MOUSE | DOMINANT | ENDOPLASMIC-RETICULUM STRESS | PROINSULIN | IDENTIFICATION | PEPTIDE | disulfide bonds | unfolded protein response | LINKAGE ANALYSIS | CHIRAL MUTAGENESIS | endoplasmic reticulum | stress insulin biosynthesis | Proinsulin - metabolism | Diabetes Mellitus - genetics | Receptors, Drug - genetics | Humans | Molecular Sequence Data | Infant | Male | Mutation, Missense | Sulfonylurea Receptors | Potassium Channels - metabolism | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - metabolism | Female | Insulin - genetics | Infant, Newborn | Genetic Linkage | Amino Acid Sequence | Protein Precursors - genetics | Diabetes Mellitus - metabolism | Potassium Channels, Inwardly Rectifying - genetics | Proinsulin - genetics | Protein Folding | Receptors, Drug - metabolism | Potassium Channels - genetics | Protein Precursors - metabolism | Models, Biological | Pedigree | Heterozygote | Potassium Channels, Inwardly Rectifying - metabolism | Infants (Newborn) | Evaluation | Gene mutations | Genetic aspects | Diagnosis | Health aspects | Diseases | Mutation | Genes | Endocrinology | Index Medicus | Biological Sciences | insulin biosynthesis | endoplasmic reticulum stress
Journal Article
Journal Article
by Ingelsson, Erik and Langenberg, Claudia and Hivert, Marie-France and Prokopenko, Inga and Lyssenko, Valeriya and Dupuis, Josée and Mägi, Reedik and Sharp, Stephen and Jackson, Anne U and Assimes, Themistocles L and Shrader, Peter and Knowles, Joshua W and Zethelius, Björn and Abbasi, Fahim A and Bergman, Richard N and Bergmann, Antje and Berne, Christian and Boehnke, Michael and Bonnycastle, Lori L and Bornstein, Stefan R and Buchanan, Thomas A and Bumpstead, Suzannah J and Böttcher, Yvonne and Chines, Peter and Collins, Francis S and Cooper, Cyrus C and Dennison, Elaine M and Erdos, Michael R and Ferrannini, Ele and Fox, Caroline S and Graessler, Jürgen and Hao, Ke and Isomaa, Bo and Jameson, Karen A and Kovacs, Peter and Kuusisto, Johanna and Laakso, Markku and Ladenvall, Claes and Mohlke, Karen L and Morken, Mario A and Narisu, Narisu and Nathan, David M and Pascoe, Laura and Payne, Felicity and Petrie, John R and Sayer, Avan A and Schwarz, Peter E. H and Scott, Laura J and Stringham, Heather M and Stumvoll, Michael and Swift, Amy J and Syvänen, Ann-Christine and Tuomi, Tiinamaija and Tuomilehto, Jaakko and Tönjes, Anke and Valle, Timo T and Williams, Gordon H and Lind, Lars and Barroso, Inês and Quertermous, Thomas and Walker, Mark and Wareham, Nicholas J and Meigs, James B and McCarthy, Mark I and Groop, Leif and Watanabe, Richard M and Florez, Jose C and MAGIC Investigators and MAGIC investigators and on behalf of the MAGIC investigators and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Molekylär medicin and Geriatrik and Uppsala universitet and Institutionen för medicinska vetenskaper and Institutionen för folkhälso- och vårdvetenskap
Diabetes, ISSN 0012-1797, 05/2010, Volume 59, Issue 5, pp. 1266 - 1275
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2016, Volume 22, Issue 4, pp. 421 - 426
Journal Article