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1. Full Text Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection
by Elizabeth B. Wilson and Douglas H. Yamada and Heidi Elsaesser and Jonathan Herskovitz and Jane Deng and Genhong Cheng and Bruce J. Aronow and Christopher L. Karp and David G. Brooks
Science (American Association for the Advancement of Science), ISSN 0036-8075, 4/2013, Volume 340, Issue 6129, pp. 202 - 207
T lymphocytes | Isotypes | Lymphocytic choriomeningitis virus | Genes | REPORTS | Blocking antibodies | Antivirals | Antibodies | Viruses | Infections | Immunity | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lymphocytic choriomeningitis virus - immunology | Arenaviridae Infections - virology | Oligonucleotide Array Sequence Analysis | Dendritic Cells - immunology | Gene Expression Profiling | Interferon-gamma - metabolism | Interferon Type I - immunology | Receptor, Interferon alpha-beta - antagonists & inhibitors | CD4-Positive T-Lymphocytes - immunology | Antibodies - immunology | Interferon Type I - metabolism | Interleukin-10 - metabolism | Lymphocytic choriomeningitis virus - physiology | Receptor, Interferon alpha-beta - genetics | Arenaviridae Infections - immunology | Cytokines - immunology | Receptor, Interferon alpha-beta - metabolism | Cytokines - metabolism | Signal Transduction | Immune Tolerance | B7-H1 Antigen - metabolism | Animals | Virus Replication | Interferon-gamma - immunology | Interferon Type I - genetics | Mice | Signal transduction | Interferon | Viral infections | Immune system | Chronic illnesses | Index Medicus | Human | HIV | Organs | Blocking | Hepatitis C virus
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2. Full Text Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells
by Tai, Zhengfu and Lin, Yuan and He, Yujiao and Huang, Junmei and Guo, Jiajia and Yang, Lijuan and Zhang, Guolin and Wang, Fei
Cellular signalling, ISSN 0898-6568, 03/2014, Volume 26, Issue 3, pp. 619 - 628
Interferon | SHP-2 | Luteolin | PKA | Phosphodiesterase | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Interferon-alpha - pharmacology | Adjuvants, Immunologic - pharmacology | STAT2 Transcription Factor - immunology | Humans | Cyclic AMP-Dependent Protein Kinases - chemistry | TYK2 Kinase - metabolism | Receptors, Cell Surface | TYK2 Kinase - immunology | Janus Kinase 1 - metabolism | STAT1 Transcription Factor - metabolism | Neoplasm Proteins | HEK293 Cells | Receptors for Activated C Kinase | Antibodies - immunology | Phosphorylation - drug effects | Receptor, Interferon alpha-beta - chemistry | Cyclic AMP - metabolism | Receptor, Interferon alpha-beta - metabolism | Phosphoric Diester Hydrolases - metabolism | Cell Survival | Colforsin - pharmacology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - antagonists & inhibitors | Phosphodiesterase Inhibitors - pharmacology | Janus Kinase 1 - antagonists & inhibitors | Luteolin - pharmacology | STAT1 Transcription Factor - antagonists & inhibitors | Janus Kinase 1 - immunology | STAT1 Transcription Factor - immunology | Hep G2 Cells | Interferon-beta - pharmacology | STAT2 Transcription Factor - antagonists & inhibitors | Signal Transduction - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | STAT2 Transcription Factor - metabolism | GTP-Binding Proteins | HeLa Cells | Immunologic Factors - pharmacology | Index Medicus | Proteins | Transducers | Pathways | Partial differential equations | Activation | Inhibition | Kinases
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3. Full Text Inhibition of Toll-Like Receptor 7- and 9-Mediated Alpha/Beta Interferon Production in Human Plasmacytoid Dendritic Cells by Respiratory Syncytial Virus and Measles Virus
by Jörg Schlender and Veit Hornung and Stefan Finke and Margit Günthner-Biller and Sabrina Marozin and Krzysztof Brzózka and Sharareh Moghim and Stefan Endres and Gunther Hartmann and Karl-Klaus Conzelmann
Journal of Virology, ISSN 0022-538X, 05/2005, Volume 79, Issue 9, pp. 5507 - 5515
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Interferon-alpha - biosynthesis | Dendritic Cells - immunology | Humans | Interferon-alpha - antagonists & inhibitors | Respiratory Syncytial Viruses - immunology | Membrane Glycoproteins - agonists | Receptors, Cell Surface - agonists | Interferon-beta - biosynthesis | Toll-Like Receptor 9 | Imidazoles - pharmacology | Receptors, Cell Surface - antagonists & inhibitors | Interferon-beta - antagonists & inhibitors | Toll-Like Receptor 7 | Measles virus - immunology | Toll-Like Receptors | Membrane Glycoproteins - antagonists & inhibitors | Time Factors | Dendritic Cells - virology | Oligodeoxyribonucleotides - pharmacology | Measles virus - pathogenicity | Respiratory Syncytial Viruses - pathogenicity | Index Medicus | Pathogenesis and Immunity
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4. Full Text DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function
by Yu, Qiujing and Katlinskaya, Yuliya V and Carbone, Christopher J and Zhao, Bin and Katlinski, Kanstantsin V and Zheng, Hui and Guha, Manti and Li, Ning and Chen, Qijun and Yang, Ting and Lengner, Christopher J and Greenberg, Roger A and Johnson, F. Brad and Fuchs, Serge Y
Cell reports (Cambridge), ISSN 2211-1247, 05/2015, Volume 11, Issue 5, pp. 785 - 797
Life Sciences & Biomedicine | Science & Technology | Cell Biology | NIH 3T3 Cells | Humans | Male | Intestines - metabolism | Stem Cells - cytology | RNA, Messenger - metabolism | Stem Cells - metabolism | Interferon Regulatory Factor-3 - genetics | Telomerase - deficiency | Antibodies, Neutralizing - immunology | Telomerase - genetics | RNA Interference | Cellular Senescence | Interferon-beta - genetics | Telomerase - metabolism | Antineoplastic Agents - pharmacology | Receptor, Interferon alpha-beta - genetics | Telomere - metabolism | Receptor, Interferon alpha-beta - metabolism | DNA Damage - drug effects | Cell Line | Intestines - pathology | Signal Transduction | Receptor, Interferon alpha-beta - deficiency | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Interferon-beta - antagonists & inhibitors | Mice, Knockout | Animals | Interferon-beta - metabolism | Interferon Regulatory Factor-3 - antagonists & inhibitors | Tamoxifen - pharmacology | Interferon Regulatory Factor-3 - metabolism | Tamoxifen - analogs & derivatives | Mice | Apoptosis | Index Medicus | senescence | stem cells | aging | interferon | DNA damage
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5. Full Text Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs
by Cheng, Liang and Ma, Jianping and Li, Jingyun and Li, Dan and Li, Guangming and Li, Feng and Zhang, Qing and Yu, Haisheng and Yasui, Fumihiko and Ye, Chaobaihui and Tsao, Li-Chung and Hu, Zhiyuan and Su, Lishan and Zhang, Liguo
The Journal of clinical investigation, ISSN 0021-9738, 01/2017, Volume 127, Issue 1, pp. 269 - 279
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Recovery of Function - genetics | Recovery of Function - drug effects | HIV Infections - genetics | Humans | Anti-Retroviral Agents - pharmacology | Signal Transduction - genetics | Interferon Type I - immunology | Receptor, Interferon alpha-beta - antagonists & inhibitors | HIV Infections - immunology | Signal Transduction - immunology | HIV-1 - immunology | Recovery of Function - immunology | Animals | HIV Infections - pathology | Receptor, Interferon alpha-beta - immunology | Signal Transduction - drug effects | Mice, Mutant Strains | Interferon Type I - genetics | HIV Infections - drug therapy | Mice | Receptor, Interferon alpha-beta - genetics | Chronic Disease | Disease Models, Animal | Care and treatment | Interferon | T cells | HIV infection | Analysis | Risk factors | Studies | Acquired immune deficiency syndrome--AIDS | Pathogenesis | Lymphocytes | Human immunodeficiency virus--HIV | Software | Infections | Laboratory animals | Gene expression | Index Medicus | Abridged Index Medicus
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6. Full Text Type i interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
by Robinson, Nirmal and McComb, Scott and Mulligan, Rebecca and Dudani, Renu and Krishnan, Lakshmi and Sad, Subash
Nature immunology, ISSN 1529-2908, 10/2012, Volume 13, Issue 10, pp. 954 - 962
Life Sciences & Biomedicine | Immunology | Science & Technology | GTPase-Activating Proteins - metabolism | Interferon Type I - immunology | Salmonella Infections, Animal - immunology | Interferon Type I - metabolism | Receptor, Interferon alpha-beta - genetics | Macrophages - immunology | Macrophages - microbiology | Macrophages - physiology | Inflammasomes | Salmonella typhimurium - immunology | Salmonella typhimurium - pathogenicity | Signal Transduction | Receptor, Interferon alpha-beta - deficiency | Salmonella Infections, Animal - metabolism | GTPase-Activating Proteins - antagonists & inhibitors | Mice, Inbred C57BL | Macrophage Activation | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Immune Evasion | Salmonella Infections, Animal - microbiology | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Receptor-Interacting Protein Serine-Threonine Kinases - antagonists & inhibitors | Apoptosis | Physiological aspects | Development and progression | Interferon | Genetic aspects | Salmonellosis | Research | Macrophages | Index Medicus
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7. Full Text Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome
by Inoue, Makoto and Williams, Kristi L and Oliver, Timothy and Vandenabeele, Peter and Rajan, Jayant V and Miao, Edward A and Shinohara, Mari L
Science signaling, ISSN 1945-0877, 05/2012, Volume 5, Issue 225, pp. ra38 - ra38
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Recombinant Proteins - therapeutic use | Proto-Oncogene Proteins c-vav - antagonists & inhibitors | Reactive Oxygen Species - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Encephalomyelitis, Autoimmune, Experimental - immunology | Suppressor of Cytokine Signaling 1 Protein | Male | Receptor, Interferon alpha-beta - physiology | Interleukin-1beta - genetics | Neuropeptides - physiology | Proto-Oncogene Proteins c-vav - physiology | Cytoskeletal Proteins - deficiency | Interferon-beta - therapeutic use | rac GTP-Binding Proteins - antagonists & inhibitors | Interleukin-1beta - biosynthesis | Caspase 1 - physiology | rac GTP-Binding Proteins - physiology | Disease Models, Animal | Carrier Proteins - physiology | Macrophages - physiology | Encephalomyelitis, Autoimmune, Experimental - physiopathology | Receptor, Interferon alpha-beta - deficiency | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | Mice, Transgenic | Mice, Knockout | Gene Expression Regulation - drug effects | Carrier Proteins - genetics | Inflammasomes - physiology | Animals | Apoptosis Regulatory Proteins | Interferon beta-1b | CD4-Positive T-Lymphocytes - transplantation | CARD Signaling Adaptor Proteins | Suppressor of Cytokine Signaling Proteins - antagonists & inhibitors | Suppressor of Cytokine Signaling Proteins - physiology | Mice | Enzyme Activation | rac1 GTP-Binding Protein | Neuropeptides - antagonists & inhibitors | Index Medicus
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8. Full Text Blocking monoclonal antibodies specific for mouse IFN-α/β receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection
by Sheehan, Kathleen C. F and Lai, Koon Siew and Dunn, Gavin P and Bruce, Allen T and Diamond, Mark S and Heutel, Jennifer D and Dungo-Arthur, Corazon and Carrero, Javier A and White, J. Michael and Hertzog, Paul J and Schreiber, Robert D
Journal of interferon & cytokine research, ISSN 1079-9907, 11/2006, Volume 26, Issue 11, pp. 804 - 819
Biochemistry & Molecular Biology | Immunology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Antibody Specificity | Gene Expression | Immunization - methods | Receptor, Interferon alpha-beta - deficiency | Plasmids - immunology | TYK2 Kinase - deficiency | Antibodies, Monoclonal - isolation & purification | Receptor, Interferon alpha-beta - antagonists & inhibitors | Mice, Knockout | TYK2 Kinase - immunology | Animals | Transfection - methods | Receptor, Interferon alpha-beta - immunology | Antibodies, Blocking - immunology | Plasmids - genetics | Mice | Receptor, Interferon alpha-beta - genetics | Antibodies, Blocking - isolation & purification | Antibodies, Monoclonal - immunology | Index Medicus
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9. Full Text Modeling Arboviral Infection in Mice Lacking the Interferon Alpha/Beta Receptor
by Marín-Lopez, Alejandro and Marín-Lopez, Alejandro and Calvo-Pinilla, Eva and Calvo-Pinilla, Eva and Moreno, Sandra and Moreno, Sandra and Utrilla-Trigo, Sergio and Utrilla-Trigo, Sergio and Nogales, Aitor and Nogales, Aitor and Brun, Alejandro and Brun, Alejandro and Fikrig, Erol and Ortego, Javier and Ortego, Javier
Viruses, ISSN 1999-4915, 01/2019, Volume 11, Issue 1, p. 35
IFNAR(−/−) mice model | pathology | interferon | vaccines | arbovirus | Life Sciences & Biomedicine | Science & Technology | Virology | Interferon-beta - immunology | Humans | Arboviruses - classification | Receptor, Interferon alpha-beta - antagonists & inhibitors | Interferon-alpha - immunology | Mice, Knockout | Animals | Virus Replication | Arboviruses - pathogenicity | Mice | Receptor, Interferon alpha-beta - genetics | Arbovirus Infections - immunology | Disease Models, Animal | Index Medicus
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