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Molecular and Cellular Endocrinology, ISSN 0303-7207, 08/2014, Volume 394, Issue 1-2, pp. 99 - 104
Cushing’s disease, a hypercortisolemic state induced by an ACTH overexpressing pituitary adenoma, causes increased morbidity and mortality. Selective... 
Antagonist | Adrenocorticotropic hormone (ACTH) | Melanocortin 2 receptor (MC2R) | Cushing’s disease | ACTIVATION | ANALOGS | MEDICAL-TREATMENT | PEPTIDE | CELL BIOLOGY | CUSHINGS-SYNDROME | Cushing's disease | ADRENOCORTICOTROPIN RECEPTOR | DISEASE | ENDOCRINOLOGY & METABOLISM | CONSENSUS STATEMENT | BINDING | RESIDUES | Receptor, Melanocortin, Type 3 - genetics | Humans | Adrenocorticotropic Hormone - pharmacology | Molecular Sequence Data | Receptor, Melanocortin, Type 3 - metabolism | Receptor, Melanocortin, Type 4 - metabolism | Structure-Activity Relationship | Receptor, Melanocortin, Type 1 - metabolism | Adrenocorticotropic Hormone - genetics | Pituitary ACTH Hypersecretion - drug therapy | Receptor, Melanocortin, Type 2 - metabolism | Dose-Response Relationship, Drug | Receptor, Melanocortin, Type 2 - genetics | Peptides - chemical synthesis | Transfection | Receptor, Melanocortin, Type 1 - chemistry | Receptors, Melanocortin - metabolism | Drug Design | HEK293 Cells | Receptor, Melanocortin, Type 2 - chemistry | Receptor, Melanocortin, Type 2 - antagonists & inhibitors | Receptor, Melanocortin, Type 3 - chemistry | Adrenocorticotropic Hormone - metabolism | Amino Acid Sequence | Gene Expression | Receptor, Melanocortin, Type 4 - chemistry | Receptor, Melanocortin, Type 1 - genetics | Receptor, Melanocortin, Type 4 - genetics | Receptors, Melanocortin - genetics | Peptides - pharmacology | Receptors, Melanocortin - chemistry | Protein Binding | Peptides
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, p. e0123232
In this study, we showed that adrenocorticotropic hormone (ACTH) promoted erythroblast differentiation and increased the enucleation ratio of erythroblasts.... 
PROGENITOR CELLS | IN-VITRO | MULTIDISCIPLINARY SCIENCES | ERYTHROPOIETIN RECEPTOR | MELANOCYTE-STIMULATING-HORMONE | ERYTHROID-CELLS | RED-BLOOD-CELLS | MOLECULAR-CLONING | EX-VIVO | PRECURSOR CELLS | HEMATOPOIETIC STEM | Adrenocorticotropic Hormone - antagonists & inhibitors | Antibodies, Neutralizing | Receptors, Melanocortin - antagonists & inhibitors | Signal Transduction | Melanocortins - metabolism | Humans | Receptor, Melanocortin, Type 1 - genetics | Cells, Cultured | Erythroblasts - metabolism | Receptor, Melanocortin, Type 1 - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | Receptor, Melanocortin, Type 1 - metabolism | Erythropoiesis - physiology | Receptors, Melanocortin - genetics | Receptor, Melanocortin, Type 2 - metabolism | Receptor, Melanocortin, Type 2 - genetics | STAT5 Transcription Factor - metabolism | Models, Biological | Receptors, Melanocortin - metabolism | Receptor, Melanocortin, Type 2 - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - metabolism | Cell Differentiation - physiology | Erythroblasts - cytology | Adrenocorticotropic Hormone - metabolism | Physiological aspects | Research | Cell differentiation | Peptide hormones | Erythrocytes | Phosphorylation | Erythropoietin | Genes | AKT protein | Biochemistry | Biology | Kinases | Accumulation | Proteins | Receptors | Rodents | Melanocortin receptors | Myosin | Pituitary gland | Inhibition | Cytokines | Actomyosin | Cloning | Contractility | Extracellular signal-regulated kinase | Cell division | Stat5 protein | Contamination | Hemopoiesis | Medicine | Enucleation | Adrenocorticotropic hormone | Placenta | Erythroblasts | Stem cells | Ligands | Transduction | Regulation | Differentiation | Endocrinology
Journal Article
American Journal of Physiology (Consolidated), ISSN 0002-9513, 07/2018, Volume 315, Issue 1, p. R128
The adrenal stress response in the neonatal rat shifts from ACTH-independent to ACTH-dependent between postnatal days 2 (PD2) and 8 (PD8). This may be due to... 
Physiological aspects | Hypoxia | Cell receptors | Peptide hormones | Corticosterone
Journal Article
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 02/2014, Volume 306, Issue 4, pp. R248 - R256
Journal Article
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 09/2012, Volume 132, Issue 9, pp. 2255 - 2262
The melanocortin 1 receptor (MC1R), a G protein–coupled receptor, has an important role in human pigmentation. We investigated the regulation of expression and... 
MELANOMA | COUPLED-RECEPTOR KINASES | DESENSITIZATION | DNA-DAMAGE | RISK | MUTATIONS | ULTRAVIOLET-RADIATION | RED HAIR | EXPRESSION | CULTURED HUMAN MELANOCYTES | DERMATOLOGY | Tetradecanoylphorbol Acetate - pharmacology | alpha-MSH - pharmacology | Humans | Receptor, Melanocortin, Type 1 - antagonists & inhibitors | Tetradecanoylphorbol Acetate - analogs & derivatives | Melanocytes - metabolism | Melanocytes - radiation effects | Monophenol Monooxygenase - metabolism | G-Protein-Coupled Receptor Kinases - biosynthesis | Ultraviolet Rays | Melanocytes - drug effects | Protein Kinase C - metabolism | Skin Pigmentation - radiation effects | Skin Pigmentation - physiology | Agouti Signaling Protein - pharmacology | Colforsin - pharmacology | Receptor, Melanocortin, Type 1 - biosynthesis | Cells, Cultured | Adenylyl Cyclases - metabolism | Skin Pigmentation - drug effects | beta-Arrestin 1 | beta-Arrestins | beta-Defensins - pharmacology | Arrestins - biosynthesis | Melanocortins - pharmacology | Receptor, Melanocortin, Type 1 - agonists | Enzymes | Protein kinase C | U.V. radiation | alpha -Melanocyte-stimulating hormone | 12-O-Tetradecanoylphorbol-13-acetate | Cyclic AMP | MC1R gene | Melanocytes | Antagonists | Monophenol monooxygenase | Pigmentation | Membrane proteins | Adenylate cyclase | beta -Arrestin | Defensins | double prime G protein-coupled receptor kinase | Forskolin | Recycling | Genotypes
Journal Article
Endocrinology, ISSN 0013-7227, 06/2009, Volume 150, Issue 6, pp. 2646 - 2653
Journal Article
Journal Article
Endocrinology, ISSN 0013-7227, 10/2007, Volume 148, Issue 10, pp. 4918 - 4926
α-MSH exerts an immunomodulatory action in the brain and may play a neuroprotective role acting through melanocortin 4 receptors (MC4Rs). In the present study,... 
NERVOUS-SYSTEM | TUMOR-NECROSIS-FACTOR | EXPERIMENTAL BRAIN INFLAMMATION | MELANOCYTE-STIMULATING HORMONE | NITRIC-OXIDE SYNTHASE | RAT ASTROCYTES | ENDOCRINOLOGY & METABOLISM | RECEPTOR MESSENGER-RNA | NF-KAPPA-B | CORTICAL ASTROCYTES | CEREBRAL-ISCHEMIA | Astrocytes - drug effects | Cell Survival - drug effects | Nitric Oxide - biosynthesis | alpha-MSH - pharmacology | Cyclooxygenase 2 Inhibitors - pharmacology | Rats, Wistar | Apoptosis - drug effects | Nitric Oxide - antagonists & inhibitors | Rats | Peptides, Cyclic - pharmacology | Receptor, Melanocortin, Type 4 - metabolism | bcl-2-Associated X Protein - antagonists & inhibitors | Proto-Oncogene Proteins c-bcl-2 - metabolism | Astrocytes - physiology | Animals | Nitric Oxide Synthase Type II - antagonists & inhibitors | Lipopolysaccharides - pharmacology | Inflammation - prevention & control | Interferon-gamma - pharmacology | Astrocytes - metabolism | Peptides; Cyclic/pharmacology | Astrocytes/drug effects/metabolism/physiology | Medical and Health Sciences | Rats; Wistar | Medicin och hälsovetenskap | Inflammation/prevention & control | Apoptosis/drug effects | Receptor; Melanocortin; Type 4/metabolism | Lipopolysaccharides/pharmacology | Cell Survival/drug effects | Nitric Oxide Synthase Type II/antagonists & inhibitors | MEDICINE | alpha-MSH/pharmacology | Interferon Type II/pharmacology | MEDICIN | Nitric Oxide/antagonists & inhibitors/biosynthesis | Cyclooxygenase 2 Inhibitors/pharmacology | Proto-Oncogene Proteins c-bcl-2/metabolism | bcl-2-Associated X Protein/antagonists & inhibitors
Journal Article