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Cell Metabolism, ISSN 1550-4131, 08/2014, Volume 20, Issue 2, pp. 333 - 345
The melanocortin system regulates metabolic homeostasis and inflammation. Melanocortin agonists have contradictorily been reported to both increase and... 
ALPHA-MSH | NERVOUS-SYSTEM | INDUCED HYPOTHERMIA | MELANOCYTE-STIMULATING HORMONE | ENERGY HOMEOSTASIS | FOOD-INTAKE | CARDIOVASCULAR FUNCTION | ENDOCRINOLOGY & METABOLISM | FRAMESHIFT MUTATION | ONSET OBESITY | FAT MASS | CELL BIOLOGY | alpha-MSH - pharmacology | Body Temperature - drug effects | Receptor, Melanocortin, Type 3 - genetics | Receptor, Melanocortin, Type 3 - metabolism | Male | Receptor, Melanocortin, Type 4 - metabolism | Receptor, Melanocortin, Type 1 - metabolism | Dopaminergic Neurons - metabolism | Receptors, Melanocortin - agonists | Receptors, Melanocortin - metabolism | Dopaminergic Neurons - drug effects | Female | Receptor, Melanocortin, Type 3 - agonists | Arcuate Nucleus of Hypothalamus - metabolism | Mice, Inbred C57BL | Receptor, Melanocortin, Type 1 - genetics | Receptor, Melanocortin, Type 4 - agonists | Receptor, Melanocortin, Type 4 - genetics | Receptors, Melanocortin - genetics | Mice, Knockout | Animals | Dopamine Antagonists - pharmacology | Mice | alpha-MSH - analogs & derivatives | Energy Metabolism - drug effects | Receptor, Melanocortin, Type 1 - agonists | Nervous system diseases | Research institutes | Kidney diseases | Hypothermia | hypotension | blood pressure | MTII | hypometabolism | hypothermia | metabolic rate | body temperature | dopamine | thermoregulation | melanocortin
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 09/2012, Volume 132, Issue 9, pp. 2255 - 2262
The melanocortin 1 receptor (MC1R), a Gs protein–coupled receptor, has an important role in human pigmentation. We investigated the regulation of expression... 
MELANOMA | COUPLED-RECEPTOR KINASES | DESENSITIZATION | DNA-DAMAGE | RISK | MUTATIONS | ULTRAVIOLET-RADIATION | RED HAIR | EXPRESSION | CULTURED HUMAN MELANOCYTES | DERMATOLOGY | Tetradecanoylphorbol Acetate - pharmacology | alpha-MSH - pharmacology | Humans | Receptor, Melanocortin, Type 1 - antagonists & inhibitors | Tetradecanoylphorbol Acetate - analogs & derivatives | Melanocytes - metabolism | Melanocytes - radiation effects | Monophenol Monooxygenase - metabolism | G-Protein-Coupled Receptor Kinases - biosynthesis | Ultraviolet Rays | Melanocytes - drug effects | Protein Kinase C - metabolism | Skin Pigmentation - radiation effects | Skin Pigmentation - physiology | Agouti Signaling Protein - pharmacology | Colforsin - pharmacology | Receptor, Melanocortin, Type 1 - biosynthesis | Cells, Cultured | Adenylyl Cyclases - metabolism | Skin Pigmentation - drug effects | beta-Arrestin 1 | beta-Arrestins | beta-Defensins - pharmacology | Arrestins - biosynthesis | Melanocortins - pharmacology | Receptor, Melanocortin, Type 1 - agonists | Enzymes | Protein kinase C | U.V. radiation | alpha -Melanocyte-stimulating hormone | 12-O-Tetradecanoylphorbol-13-acetate | Cyclic AMP | MC1R gene | Melanocytes | Antagonists | Monophenol monooxygenase | Pigmentation | Membrane proteins | Adenylate cyclase | beta -Arrestin | Defensins | double prime G protein-coupled receptor kinase | Forskolin | Recycling | Genotypes
Journal Article
Endocrinology, ISSN 0013-7227, 06/2009, Volume 150, Issue 6, pp. 2646 - 2653
Journal Article
Neuron, ISSN 0896-6273, 2006, Volume 51, Issue 2, pp. 239 - 249
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 08/2010, Volume 21, Issue 8, pp. 1290 - 1298
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2015, Volume 194, Issue 7, pp. 3381 - 3388
There is a need for novel approaches to control pathologies with overexuberant inflammatory reactions. Targeting melanocortin (MC) receptors represents a... 
MOLECULAR-MECHANISM | PATHWAYS | ACTIVATION | MANAGEMENT | MELANOCYTE-STIMULATING HORMONE | RESOLUTION | DISEASE | INFLAMMATORY ARTHRITIS | IMMUNOLOGY | MODULATION | ADRENOCORTICOTROPIC HORMONE | Inflammation - pathology | Arthritis, Experimental - drug therapy | Arthritis, Experimental - genetics | Calcium - metabolism | Receptor, Melanocortin, Type 3 - genetics | Humans | Receptor, Melanocortin, Type 3 - metabolism | Guanidines - pharmacology | Male | Receptor, Melanocortin, Type 1 - metabolism | Melanins - metabolism | Arthritis, Experimental - metabolism | Arthritis, Experimental - pathology | Peritonitis - pathology | Inflammation - metabolism | Melanoma, Experimental | Inflammation - drug therapy | Peritonitis - genetics | Pyrroles - administration & dosage | Receptors, Melanocortin - agonists | Receptors, Melanocortin - metabolism | HEK293 Cells | Anti-Inflammatory Agents - administration & dosage | Macrophages, Peritoneal - drug effects | Neutrophils - metabolism | Receptor, Melanocortin, Type 3 - agonists | Guanidines - administration & dosage | Disease Models, Animal | Anti-Inflammatory Agents - pharmacology | Peritonitis - metabolism | Receptor, Melanocortin, Type 1 - genetics | Neutrophils - immunology | Phagocytosis - immunology | Macrophages, Peritoneal - immunology | Peritonitis - chemically induced | Gene Knockout Techniques | Receptors, Melanocortin - genetics | Pyrroles - pharmacology | Animals | Signal Transduction - drug effects | Inflammation - genetics | Mice | Peritonitis - drug therapy | Macrophages, Peritoneal - metabolism | Receptor, Melanocortin, Type 1 - agonists
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2011, Volume 179, Issue 1, pp. 259 - 269
Synthetic and natural melanocortin (MC) peptides afford inhibitory properties in inflammation and tissue injury, but characterization of receptor involvement... 
Pathology | ALPHA-MSH | IN-VITRO | MELANOCYTE-STIMULATING HORMONE | MACROPHAGE PHAGOCYTOSIS | NEUTROPHIL MIGRATION | NONPHLOGISTIC PHAGOCYTOSIS | APOPTOTIC CELLS | RESOLUTION | INFLAMMATORY ARTHRITIS | PATHOLOGY | T-CELLS | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Neutrophils - cytology | Arthritis, Experimental - drug therapy | alpha-MSH - pharmacology | Apoptosis - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Male | Interleukin-1beta - genetics | Macrophages, Peritoneal - cytology | Melanocortins - agonists | Arthritis, Experimental - metabolism | Arthritis, Experimental - pathology | Peritonitis - pathology | Inflammation - metabolism | Inflammation - drug therapy | Interleukin-1beta - metabolism | Cytokines - genetics | Interleukin-6 - metabolism | Macrophages, Peritoneal - drug effects | Neutrophils - metabolism | Disease Models, Animal | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Interleukin-6 - genetics | Mice, Inbred C57BL | Neutrophils - drug effects | Peritonitis - metabolism | RNA, Messenger - genetics | Receptor, Melanocortin, Type 1 - physiology | Macrophages - cytology | Mutation - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Macrophages - metabolism | Animals | Macrophages - drug effects | Mice | Receptor, Melanocortin, Type 3 - physiology | Peritonitis - drug therapy | Macrophages, Peritoneal - metabolism | alpha-MSH - analogs & derivatives | Phagocytosis | Regular
Journal Article
Peptides, ISSN 0196-9781, 2009, Volume 30, Issue 10, pp. 1892 - 1900
Journal Article
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2011, Volume 660, Issue 1, pp. 80 - 87
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 2016, Volume 41, Issue 9, pp. 2241 - 2251
Journal Article