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Molecular and Cellular Endocrinology, ISSN 0303-7207, 08/2014, Volume 394, Issue 1-2, pp. 99 - 104
Cushing’s disease, a hypercortisolemic state induced by an ACTH overexpressing pituitary adenoma, causes increased morbidity and mortality. Selective... 
Antagonist | Adrenocorticotropic hormone (ACTH) | Melanocortin 2 receptor (MC2R) | Cushing’s disease | ACTIVATION | ANALOGS | MEDICAL-TREATMENT | PEPTIDE | CELL BIOLOGY | CUSHINGS-SYNDROME | Cushing's disease | ADRENOCORTICOTROPIN RECEPTOR | DISEASE | ENDOCRINOLOGY & METABOLISM | CONSENSUS STATEMENT | BINDING | RESIDUES | Receptor, Melanocortin, Type 3 - genetics | Humans | Adrenocorticotropic Hormone - pharmacology | Molecular Sequence Data | Receptor, Melanocortin, Type 3 - metabolism | Receptor, Melanocortin, Type 4 - metabolism | Structure-Activity Relationship | Receptor, Melanocortin, Type 1 - metabolism | Adrenocorticotropic Hormone - genetics | Pituitary ACTH Hypersecretion - drug therapy | Receptor, Melanocortin, Type 2 - metabolism | Dose-Response Relationship, Drug | Receptor, Melanocortin, Type 2 - genetics | Peptides - chemical synthesis | Transfection | Receptor, Melanocortin, Type 1 - chemistry | Receptors, Melanocortin - metabolism | Drug Design | HEK293 Cells | Receptor, Melanocortin, Type 2 - chemistry | Receptor, Melanocortin, Type 2 - antagonists & inhibitors | Receptor, Melanocortin, Type 3 - chemistry | Adrenocorticotropic Hormone - metabolism | Amino Acid Sequence | Gene Expression | Receptor, Melanocortin, Type 4 - chemistry | Receptor, Melanocortin, Type 1 - genetics | Receptor, Melanocortin, Type 4 - genetics | Receptors, Melanocortin - genetics | Peptides - pharmacology | Receptors, Melanocortin - chemistry | Protein Binding | Peptides
Journal Article
Cell Metabolism, ISSN 1550-4131, 08/2014, Volume 20, Issue 2, pp. 333 - 345
The melanocortin system regulates metabolic homeostasis and inflammation. Melanocortin agonists have contradictorily been reported to both increase and... 
ALPHA-MSH | NERVOUS-SYSTEM | INDUCED HYPOTHERMIA | MELANOCYTE-STIMULATING HORMONE | ENERGY HOMEOSTASIS | FOOD-INTAKE | CARDIOVASCULAR FUNCTION | ENDOCRINOLOGY & METABOLISM | FRAMESHIFT MUTATION | ONSET OBESITY | FAT MASS | CELL BIOLOGY | alpha-MSH - pharmacology | Body Temperature - drug effects | Receptor, Melanocortin, Type 3 - genetics | Receptor, Melanocortin, Type 3 - metabolism | Male | Receptor, Melanocortin, Type 4 - metabolism | Receptor, Melanocortin, Type 1 - metabolism | Dopaminergic Neurons - metabolism | Receptors, Melanocortin - agonists | Receptors, Melanocortin - metabolism | Dopaminergic Neurons - drug effects | Female | Receptor, Melanocortin, Type 3 - agonists | Arcuate Nucleus of Hypothalamus - metabolism | Mice, Inbred C57BL | Receptor, Melanocortin, Type 1 - genetics | Receptor, Melanocortin, Type 4 - agonists | Receptor, Melanocortin, Type 4 - genetics | Receptors, Melanocortin - genetics | Mice, Knockout | Animals | Dopamine Antagonists - pharmacology | Mice | alpha-MSH - analogs & derivatives | Energy Metabolism - drug effects | Receptor, Melanocortin, Type 1 - agonists | Nervous system diseases | Research institutes | Kidney diseases | Hypothermia | hypotension | blood pressure | MTII | hypometabolism | hypothermia | metabolic rate | body temperature | dopamine | thermoregulation | melanocortin
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2015, Volume 194, Issue 7, pp. 3381 - 3388
There is a need for novel approaches to control pathologies with overexuberant inflammatory reactions. Targeting melanocortin (MC) receptors represents a... 
MOLECULAR-MECHANISM | PATHWAYS | ACTIVATION | MANAGEMENT | MELANOCYTE-STIMULATING HORMONE | RESOLUTION | DISEASE | INFLAMMATORY ARTHRITIS | IMMUNOLOGY | MODULATION | ADRENOCORTICOTROPIC HORMONE | Inflammation - pathology | Arthritis, Experimental - drug therapy | Arthritis, Experimental - genetics | Calcium - metabolism | Receptor, Melanocortin, Type 3 - genetics | Humans | Receptor, Melanocortin, Type 3 - metabolism | Guanidines - pharmacology | Male | Receptor, Melanocortin, Type 1 - metabolism | Melanins - metabolism | Arthritis, Experimental - metabolism | Arthritis, Experimental - pathology | Peritonitis - pathology | Inflammation - metabolism | Melanoma, Experimental | Inflammation - drug therapy | Peritonitis - genetics | Pyrroles - administration & dosage | Receptors, Melanocortin - agonists | Receptors, Melanocortin - metabolism | HEK293 Cells | Anti-Inflammatory Agents - administration & dosage | Macrophages, Peritoneal - drug effects | Neutrophils - metabolism | Receptor, Melanocortin, Type 3 - agonists | Guanidines - administration & dosage | Disease Models, Animal | Anti-Inflammatory Agents - pharmacology | Peritonitis - metabolism | Receptor, Melanocortin, Type 1 - genetics | Neutrophils - immunology | Phagocytosis - immunology | Macrophages, Peritoneal - immunology | Peritonitis - chemically induced | Gene Knockout Techniques | Receptors, Melanocortin - genetics | Pyrroles - pharmacology | Animals | Signal Transduction - drug effects | Inflammation - genetics | Mice | Peritonitis - drug therapy | Macrophages, Peritoneal - metabolism | Receptor, Melanocortin, Type 1 - agonists
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2006, Volume 149, Issue 7, pp. 815 - 827
Journal Article