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Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7594, pp. 335 - 340
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2010, Volume 107, Issue 6, pp. 2693 - 2698
Journal Article
Neuroscience, ISSN 0306-4522, 2017, Volume 357, pp. 84 - 98
Highlights • M1 receptor expression is increased in the dorsomedial striatum of dtsz hamsters. • M2/M4 receptor binding is altered in limbic structures of dtsz... 
Neurology | muscarinic | basal ganglia | acetylcholine | movement disorders | striatum | PRIMARY PAROXYSMAL DYSTONIA | PARVALBUMIN-POSITIVE INTERNEURONS | PROJECTION NEURONS | SUBTYPE-SPECIFIC ANTIBODIES | NEUROSCIENCES | MUTANT HAMSTERS | disorders | AGE-RELATED-CHANGES | GABAERGIC INTERNEURONS | STRIATAL CHOLINERGIC INTERNEURONS | ANIMAL-MODEL | movement | RODENT MODEL | Limbic System - pathology | Dystonia - pathology | Male | Receptor, Muscarinic M1 - antagonists & inhibitors | Dystonia - metabolism | Limbic System - metabolism | Thiophenes - administration & dosage | Corpus Striatum - metabolism | Dose-Response Relationship, Drug | Mesocricetus | Female | Anti-Dyskinesia Agents - administration & dosage | Drug Therapy, Combination | Corpus Striatum - pathology | Disease Models, Animal | Limbic System - drug effects | Severity of Illness Index | Pyridines - administration & dosage | Receptor, Muscarinic M4 - metabolism | Dystonia - drug therapy | Disease Progression | Muscarinic Antagonists - administration & dosage | Animals | Corpus Striatum - drug effects | Tropicamide - administration & dosage | Mutation | Receptor, Muscarinic M4 - antagonists & inhibitors | Trihexyphenidyl - administration & dosage | Receptor, Muscarinic M1 - metabolism | Hamsters | Analysis | Parasympatholytic agents | Movement disorders | Index Medicus
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2008, Volume 117, Issue 2, pp. 232 - 243
Muscarinic acetylcholine receptors (mAChRs) are widely expressed in the CNS where they control a variety of neuronal functions. Due to their roles in a number... 
Parkinson's disease | mAChR | Schizophrenia | CNS | Drug dependence | Muscarinic receptors | Alzheimer's disease | AFFINITY AGONIST BINDING | ALZHEIMERS-DISEASE | schizophrenia | AMYLOID PRECURSOR PROTEIN | SUBSTANTIA-NIGRA | drug dependence | PEDUNCULOPONTINE TEGMENTAL NUCLEUS | muscarinic receptors | EXPERIMENTAL CHOLINERGIC DENERVATION | M-1 RECEPTOR | A-BETA | PHARMACOLOGY & PHARMACY | HAMSTER OVARY-M1 CELLS | NIGRA PARS COMPACTA | Central Nervous System Agents - therapeutic use | Schizophrenia - metabolism | Antiparkinson Agents - pharmacology | Central Nervous System - metabolism | Muscarinic Agonists - pharmacology | Humans | Muscarinic Agonists - therapeutic use | Receptor, Muscarinic M2 - drug effects | Receptors, Muscarinic - metabolism | Parkinson Disease - drug therapy | Muscarinic Antagonists - therapeutic use | Receptors, Muscarinic - drug effects | Receptor, Muscarinic M1 - drug effects | Muscarinic Antagonists - pharmacology | Parkinson Disease - metabolism | Substance-Related Disorders - metabolism | Receptor, Muscarinic M2 - metabolism | Alzheimer Disease - drug therapy | Receptor, Muscarinic M4 - metabolism | Animals | Receptor, Muscarinic M4 - drug effects | Alzheimer Disease - metabolism | Central Nervous System Agents - pharmacology | Central Nervous System - drug effects | Antipsychotic Agents - pharmacology | Schizophrenia - drug therapy | Substance-Related Disorders - drug therapy | Receptor, Muscarinic M1 - metabolism | Antipsychotic drugs | Antiparkinsonian agents
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2008, Volume 28, Issue 41, pp. 10422 - 10433
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2013, Volume 56, Issue 12, pp. 5151 - 5172
Established therapy in Alzheimer’s disease involves potentiation of the endogenous orthosteric ligand, acetylcholine, at the M1 muscarinic receptors found in... 
Allosteric Regulation - drug effects | Cricetinae | Chemistry Techniques, Synthetic | Cricetulus | Humans | Quinolines - chemistry | Structure-Activity Relationship | Quinolines - pharmacology | Quinolines - chemical synthesis | Receptor, Muscarinic M1 - chemistry | Animals | Drug Design | Binding Sites | Receptor, Muscarinic M1 - metabolism | CHO Cells
Journal Article