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JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 11/2017, Volume 60, Issue 22, pp. 9239 - 9250
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 08/2008, Volume 74, Issue 2, pp. 338 - 347
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 38, pp. E5675 - E5684
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 2014, Volume 85, Issue 5, pp. 758 - 768
Journal Article
Journal of Pharmacological and Toxicological Methods, ISSN 1056-8719, 11/2013, Volume 68, Issue 3, pp. 323 - 333
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2017, Volume 127, Issue 2, pp. 720 - 734
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 10/2010, Volume 162, Issue 1, pp. 53 - 61
Journal Article
Microvascular Research, ISSN 0026-2862, 11/2017, Volume 114, pp. 1 - 11
The objectives of this study were to evaluate, and the contribution of muscarinic receptors to the effects of extract. extract was tested in competition... 
In vitro and in vivo studies | Inflammation | Muscarinic receptors | Hamster cheek pouch microcirculation | Venotonic drug | PERIMALLEOLAR REGION | VEINS | HAMSTER-CHEEK POUCH | CHRONIC VENOUS INSUFFICIENCY | MICROCIRCULATION | MACROMOLECULAR PERMEABILITY | INDEPENDENT CUTANEOUS VASODILATION | PATHOPHYSIOLOGY | ACETYLCHOLINE-RECEPTORS | PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | Leukocyte Rolling - drug effects | Cricetulus | Muscarinic Agonists - pharmacology | Plant Extracts - pharmacology | Humans | Capillary Permeability - drug effects | Male | Receptors, Muscarinic - metabolism | Anti-Inflammatory Agents - metabolism | Microcirculation - drug effects | Dose-Response Relationship, Drug | Receptor, Muscarinic M1 - agonists | Inflammation - metabolism | Plant Extracts - metabolism | Muscarinic Agonists - isolation & purification | Receptors, Muscarinic - drug effects | Transfection | Muscarinic Agonists - metabolism | Mesocricetus | Anti-Inflammatory Agents - isolation & purification | Phytotherapy | Reperfusion Injury - metabolism | CHO Cells | Disease Models, Animal | Receptors, Muscarinic - genetics | Binding, Competitive | Drug Partial Agonism | Anti-Inflammatory Agents - pharmacology | Receptor, Muscarinic M3 - metabolism | Plant Extracts - isolation & purification | Cheek - blood supply | Inflammation - immunology | Receptor, Muscarinic M3 - genetics | Animals | Reperfusion Injury - prevention & control | Ruscus - chemistry | Calcium Signaling - drug effects | Reperfusion Injury - immunology | Reperfusion Injury - physiopathology | Protein Binding | Inflammation - prevention & control | Receptor, Muscarinic M3 - agonists | Plants, Medicinal | Receptor, Muscarinic M1 - metabolism | Inflammation - physiopathology | Histamine | Analysis | Permeability
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 04/2013, Volume 123, Issue 4, pp. 1750 - 1762
Type 2 diabetes (T2D) has emerged as a major threat to human health in most parts of the world. Therapeutic strategies aimed at improving pancreatic beta cell... 
TRANSCRIPTION FACTORS | MEDICINE, RESEARCH & EXPERIMENTAL | REGULATOR | SIGNALING PATHWAYS | SUBSTRATE-2 | INSULIN-RESISTANCE | PROTEIN-COUPLED RECEPTORS | MECHANISMS | DIFFERENTIATION | SECRETION | EXPRESSION | Cell Proliferation | Gene Expression - drug effects | Receptors, G-Protein-Coupled - metabolism | Muscarinic Agonists - pharmacology | Male | Receptor, Muscarinic M3 - physiology | Insulin Receptor Substrate Proteins - metabolism | Receptors, G-Protein-Coupled - agonists | Molecular Targeted Therapy | MAP Kinase Signaling System | Clozapine - pharmacology | Insulin-Secreting Cells - metabolism | Diabetes Mellitus, Experimental - prevention & control | Protein Engineering | Female | Drug Evaluation, Preclinical | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Insulin Receptor Substrate Proteins - genetics | Insulin-Secreting Cells - physiology | Recombinant Proteins - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Insulin Receptor Substrate Proteins - physiology | Mice, Inbred C57BL | Mice, Transgenic | Recombinant Proteins - agonists | Recombinant Proteins - genetics | Clozapine - analogs & derivatives | Hypoglycemic Agents - pharmacology | Animals | Insulin-Secreting Cells - drug effects | Cell Line, Tumor | Diabetes Mellitus, Experimental - pathology | Mice | Receptors, G-Protein-Coupled - genetics | Receptor, Muscarinic M3 - agonists
Journal Article