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Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
Cancer research (Chicago, Ill.), ISSN 0008-5472, 01/2010, Volume 70, Issue 2, pp. 709 - 718
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Signal Transduction | Receptors, Notch - metabolism | Humans | Hyaluronan Receptors - biosynthesis | Receptor, Notch1 - metabolism | Breast Neoplasms - metabolism | Mice, Knockout | Membrane Proteins - biosynthesis | Receptors, Notch - antagonists & inhibitors | Animals | Neoplastic Stem Cells - metabolism | Breast Neoplasms - pathology | Mice, Nude | Cell Line, Tumor | Neoplastic Stem Cells - pathology | Mice | CD24 Antigen - biosynthesis | Receptor, Notch4 | Index Medicus | stem cells | gamma secretase inhibitors | Breast cancer | CD44 | Notch receptors
Journal Article
Cancer letters, ISSN 0304-3835, 2017, Volume 390, pp. 115 - 125
Hematology, Oncology and Palliative Medicine | Notch4 | Breast cancer | Metastasis | Tamoxifen resistance | STAT3 | Life Sciences & Biomedicine | Oncology | Science & Technology | Cell Proliferation | Receptors, Notch - metabolism | Epithelial-Mesenchymal Transition - physiology | Humans | Epithelial-Mesenchymal Transition - drug effects | Immunoblotting | Breast Neoplasms - physiopathology | Receptors, Notch - antagonists & inhibitors | Antineoplastic Agents, Hormonal - therapeutic use | Polymerase Chain Reaction | Female | STAT3 Transcription Factor - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Antineoplastic Agents, Hormonal - pharmacology | Breast Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | Animals | Signal Transduction - drug effects | Mice, Nude | Tamoxifen - therapeutic use | Tamoxifen - pharmacology | Cell Line, Tumor | Protein Binding | Signal Transduction - physiology | Receptor, Notch4 | Proteins | Tyrosine | Medical colleges | Analysis | Pharmacy | Liver | Stem cells | Drugstores | Development and progression | Tamoxifen | Polyols | Index Medicus
Journal Article
Cancer science, ISSN 1347-9032, 08/2016, Volume 107, Issue 8, pp. 1079 - 1091
Cancer stem cell | epithelial–mesenchymal transition | melanoma | Notch4 protein | Twist1 | Epithelial-mesenchymal transition | Melanoma | Life Sciences & Biomedicine | Oncology | Science & Technology | Melanoma - metabolism | Proto-Oncogene Proteins - metabolism | Cadherins - metabolism | Receptors, Notch - metabolism | Humans | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Receptors, Notch - genetics | Melanoma - pathology | Proto-Oncogene Proteins - deficiency | Epithelial-Mesenchymal Transition - genetics | Neoplasm Metastasis - genetics | Neoplastic Stem Cells - metabolism | Melanoma - genetics | Cell Line, Tumor | Neoplastic Stem Cells - pathology | Neoplasm Invasiveness - genetics | Receptors, Notch - deficiency | Twist-Related Protein 1 - metabolism | Receptor, Notch4 | Epidermal growth factor | Analysis | Genes | Stem cells | Fibroblast growth factors | B cells | Metastasis | Gene expression | Cancer | Vimentin | Cell culture | Flow cytometry | Fibroblast growth factor | Mesenchyme | Western blotting | NOTCH4 protein | Metastases | Proteins | Angiogenesis | Signal transduction | Transfection | Vascular endothelial growth factor | Fibroblast growth factor 2 | Medical research | Immunoglobulins | Invasiveness | DNA microarrays | Protein expression | Immunofluorescence | Secretase | Tumors | Index Medicus | Original
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 04/2016, Volume 76, Issue 7, pp. 1690 - 1697
Journal Article
Human molecular genetics, ISSN 0964-6906, 09/2012, Volume 21, Issue 18, pp. 4138 - 4150
Fundamental and applied biological sciences. Psychology | Retinopathies | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Ophthalmology | Haplotypes | Genetic Predisposition to Disease | Genome-Wide Association Study | Tenascin - genetics | Humans | Linear Models | Logistic Models | Male | Proto-Oncogene Proteins - genetics | Receptors, Notch - genetics | Genetic Loci | Chromosomes, Human, Pair 6 | Sequence Analysis, DNA | Case-Control Studies | Immunophilins - genetics | Macular Degeneration - genetics | Aged, 80 and over | Female | Aged | Polymorphism, Single Nucleotide | Odds Ratio | Principal Component Analysis | Receptor, Notch4 | Index Medicus | Association Studies
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 12/2008, Volume 28, Issue 12, pp. 2258 - 2265
Transplant arteriosclerosis | Activation | Endothelial cells | Notch | Apoptosis | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Cardiology. Vascular system | Blood vessels and receptors | Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous | Atherosclerosis (general aspects, experimental research) | Biological and medical sciences | Medical sciences | Vertebrates: cardiovascular system | Blood and lymphatic vessels | RNA, Small Interfering - genetics | Transcription Factor HES-1 | Humans | Rats, Inbred Lew | Heart Transplantation - pathology | Receptors, Notch - genetics | RNA, Messenger - metabolism | Transplantation, Homologous | Receptors, Notch - antagonists & inhibitors | Coronary Artery Disease - physiopathology | Inflammation Mediators - pharmacology | Coronary Artery Disease - pathology | Heart Transplantation - physiology | Inflammation Mediators - metabolism | Endothelial Cells - physiology | Proto-Oncogene Proteins - antagonists & inhibitors | Basic Helix-Loop-Helix Transcription Factors - physiology | Basic Helix-Loop-Helix Transcription Factors - genetics | Coronary Artery Disease - etiology | Cytokines - metabolism | Signal Transduction | Down-Regulation | RNA, Messenger - genetics | Cells, Cultured | Gene Silencing | Heart Transplantation - adverse effects | Rats | Receptors, Notch - physiology | Proto-Oncogene Proteins - genetics | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | Homeodomain Proteins - genetics | Animals | Homeodomain Proteins - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Apoptosis - physiology | Endothelial Cells - pathology | Homeodomain Proteins - physiology | Cytokines - pharmacology | Receptor, Notch4 | Index Medicus
Journal Article
Scientific reports, ISSN 2045-2322, 2015, Volume 5, Issue 1, pp. 8782 - 8782
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Proto-Oncogene Proteins - metabolism | Cell Line | Phosphorylation | Receptors, Notch - metabolism | Humans | Proto-Oncogene Proteins - chemistry | 14-3-3 Proteins - metabolism | Animals | Receptors, Notch - chemistry | Protein Binding | Protein Interaction Domains and Motifs | Active Transport, Cell Nucleus | Proto-Oncogene Proteins c-akt - metabolism | Binding Sites | Cytoplasm | Receptor, Notch4 | Cell proliferation | Inositol | Transcription | Stem cell transplantation | AKT protein | Breast cancer | Kinases | Nuclei | 1-Phosphatidylinositol 3-kinase | 14-3-3 protein | Cell fate | Stem cells | Regulation | Notch protein | Localization | Growth factors | Regulatory proteins | Tumors | Index Medicus
Journal Article
Clinical cancer research, ISSN 1078-0432, 02/2018, Volume 24, Issue 3, pp. 619 - 633
Life Sciences & Biomedicine | Oncology | Science & Technology | Squamous Cell Carcinoma of Head and Neck - metabolism | Cell Cycle - genetics | Receptor, Notch4 - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Signal Transduction | Humans | Squamous Cell Carcinoma of Head and Neck - pathology | Cell Cycle Proteins - metabolism | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Cisplatin - pharmacology | Epithelial-Mesenchymal Transition - genetics | Receptor, Notch4 - genetics | Squamous Cell Carcinoma of Head and Neck - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cell Cycle Proteins - genetics | Cell Line, Tumor | Cell Cycle - drug effects | Vimentin | Cell proliferation | Squamous cell carcinoma | Phenotypes | Mesenchyme | Gene expression | Tissues | E-cadherin | Cisplatin | Fibronectin | Cell adhesion & migration | Datasets | Receptors | Experimental design | Head and neck cancer | Notch protein | Mutation | Viability | Cell migration | Apoptosis | Head and neck squamous cell carcinoma | HEY1 | EMT | NOTCH4 | TCGA
Journal Article
Journal of rheumatology, ISSN 0315-162X, 02/2019, Volume 46, Issue 2, pp. 184 - 189
NOTCH4 GENE | SYSTEMIC SCLEROSIS | EXONIC VARIANTS | Life Sciences & Biomedicine | Rheumatology | Science & Technology | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Scleroderma, Systemic - blood | Follow-Up Studies | Humans | Asian Continental Ancestry Group - genetics | Scleroderma, Systemic - genetics | Exons - genetics | Genotype | Logistic Models | Receptor, Notch4 - genetics | Alleles | Polymorphism, Single Nucleotide - genetics | High-Throughput Nucleotide Sequencing | Histocompatibility Antigens Class II - genetics | Autoantibodies - genetics | Tandem Repeat Sequences - genetics | Scleroderma, Systemic - ethnology | Index Medicus
Journal Article
Molecular and cellular biochemistry, ISSN 0300-8177, 3/2015, Volume 401, Issue 1, pp. 165 - 174
Life Sciences | Biochemistry, general | β-catenin | Growth | Notch | Medical Biochemistry | Oncology | Cardiology | Wnt1 | Gastric cancer | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proto-Oncogene Proteins - metabolism | Neoplasm Transplantation | Up-Regulation | Adenocarcinoma - pathology | Cell Proliferation | Receptors, Notch - metabolism | Tissue Array Analysis | Humans | Gene Expression Regulation, Neoplastic | Stomach Neoplasms - metabolism | Stomach Neoplasms - pathology | beta Catenin - metabolism | Adenocarcinoma - metabolism | Cell Line, Tumor | Female | Receptor, Notch4 | Wnt Signaling Pathway | Index Medicus
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