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Science Translational Medicine, ISSN 1946-6234, 10/2009, Volume 1, Issue 1, pp. 1ra1 - 1ra1
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2017, Volume 292, Issue 24, pp. 9865 - 9881
The glucagon receptor (GCGR) belongs to the secretin-like (class B) family of G protein-coupled receptors (GPCRs) and is activated by the peptide hormone... 
BETA ADRENERGIC-RECEPTOR | LIGAND-BINDING | GLUCAGON RECEPTOR | IONIC LOCK | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CROSS-LINKING STRATEGY | METAPHYSEAL CHONDRODYSPLASIA | BETA-ADRENERGIC RECEPTOR | PEPTIDE | MUSCARINIC ACETYLCHOLINE-RECEPTOR | Receptor, Parathyroid Hormone, Type 1 - chemistry | Receptors, Corticotropin-Releasing Hormone - metabolism | Receptor, Parathyroid Hormone, Type 1 - metabolism | Humans | Receptors, Corticotropin-Releasing Hormone - agonists | Receptors, Corticotropin-Releasing Hormone - genetics | Receptor, Parathyroid Hormone, Type 1 - agonists | Recombinant Fusion Proteins - metabolism | Receptors, Vasoactive Intestinal Polypeptide, Type I - agonists | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - chemistry | Conserved Sequence | Protein Interaction Domains and Motifs | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - agonists | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Receptors, Vasoactive Intestinal Polypeptide, Type I - metabolism | Protein Stability | Binding Sites | Peptide Fragments - genetics | Second Messenger Systems | Receptors, Glucagon - agonists | Receptors, Glucagon - genetics | Receptors, Vasoactive Intestinal Polypeptide, Type I - chemistry | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Peptide Fragments - metabolism | Mutagenesis, Site-Directed | Models, Molecular | Receptors, Glucagon - metabolism | Recombinant Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Receptors, Vasoactive Intestinal Polypeptide, Type I - genetics | Peptide Fragments - chemistry | Peptide Fragments - agonists | Receptors, Glucagon - chemistry | Hydrophobic and Hydrophilic Interactions | Receptor, Parathyroid Hormone, Type 1 - genetics | Ligands | Protein Conformation | Structural Homology, Protein | Mutation | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Receptors, Corticotropin-Releasing Hormone - chemistry | Amino Acid Substitution | Index Medicus | Editors' Picks | 7-helix receptor | G protein-coupled receptor (GPCR) | parathyroid hormone | glucagon | arrestin
Journal Article
Osteoporosis International, ISSN 0937-941X, 3/2018, Volume 29, Issue 3, pp. 685 - 697
Abaloparatide, a novel PTH1 receptor agonist, increased bone formation in osteopenic ovariectomized cynomolgus monkeys while increasing cortical and trabecular... 
Osteoporosis | Abaloparatide | Medicine & Public Health | Orthopedics | Rheumatology | Bone quality | PTH1R | Bone strength | Endocrinology | CORTICAL BONE | RHESUS-MONKEYS | HUMAN RANKL ANTIBODY | TERIPARATIDE | MINERAL DENSITY | BIOMECHANICAL PROPERTIES | ENDOCRINOLOGY & METABOLISM | PARATHYROID-HORMONE | POSTMENOPAUSAL WOMEN | PROXIMAL FEMUR | Bone Resorption - physiopathology | Osteogenesis - physiology | Bone Density - physiology | Ovariectomy | Osteogenesis - drug effects | Bone Density Conservation Agents - therapeutic use | Macaca fascicularis | Procollagen - blood | Biomarkers - blood | Receptor, Parathyroid Hormone, Type 1 - agonists | X-Ray Microtomography - methods | Bone Density Conservation Agents - pharmacology | Parathyroid Hormone-Related Protein - pharmacology | Parathyroid Hormone-Related Protein - therapeutic use | Bone Resorption - prevention & control | Bone Density - drug effects | Animals | Peptide Fragments - blood | Absorptiometry, Photon - methods | Female | Lumbar Vertebrae - physiopathology | Bone resorption | Bones | Care and treatment | Density | Analysis | Femur | Calcium | Bone (trabecular) | Diaphysis | Bone histomorphometry | Bone growth | Calcium (blood) | Vitamin D | Computed tomography | Surgery | Bone density | Densitometry | Bone (cortical) | Dual energy X-ray absorptiometry | Vertebrae | Bone turnover | Post-menopause | Bone mass | Parathyroid hormone | Porosity | Humerus | Osteogenesis | Original
Journal Article
Bone, ISSN 8756-3282, 12/2006, Volume 39, Issue 6, pp. 1361 - 1372
Whereas continuous PTH infusion increases bone resorption and bone loss, intermittent PTH treatment stimulates bone formation, in part, via reactivation of... 
Bone marrow | Osteoporosis | Adipocyte | Osteoprogenitor | Parathyroid hormone | parathyroid hormone | OSTEOBLAST DIFFERENTIATION | OSTEOGENIC CELLS | MESENCHYMAL CELLS | OSTEOPROGENITOR CELLS | osteoporosis | ADIPOGENESIS | OVARIECTOMIZED RATS | bone marrow | osteoprogenitor | TRABECULAR BONE | adipocyte | IN-VIVO | ENDOCRINOLOGY & METABOLISM | PTH/PTHRP RECEPTOR | EXPRESSION | Gene Expression - drug effects | Humans | Alkaline Phosphatase - metabolism | Adipocytes - cytology | DNA Primers - genetics | Adipocytes - drug effects | Receptor, Parathyroid Hormone, Type 1 - agonists | Cell Differentiation - genetics | Mesenchymal Stromal Cells - cytology | Barbiturates - pharmacology | Base Sequence | Stromal Cells - drug effects | Bone Marrow Cells - drug effects | Osteoblasts - cytology | Cell Differentiation - physiology | Cyclic AMP - metabolism | Cell Line | Mesenchymal Stromal Cells - drug effects | Teriparatide - pharmacology | Bone Marrow Cells - cytology | Osteoblasts - drug effects | Stromal Cells - metabolism | Mesenchymal Stromal Cells - metabolism | Lipid Metabolism | Adenylyl Cyclases - metabolism | Genetic Markers | Glycerolphosphate Dehydrogenase - metabolism | Cell Differentiation - drug effects | Adipocytes - metabolism | Receptor, Parathyroid Hormone, Type 1 - genetics | Osteoblasts - metabolism | Bone Marrow Cells - metabolism | Stromal Cells - cytology | Hormones
Journal Article
Journal Article
Regulatory Peptides, ISSN 0167-0115, 11/2011, Volume 171, Issue 1-3, pp. 35 - 42
Recent data suggests that chronic renal failure and hyperparathyroidism are associated with sympathetic overactivity. Since peptide hormones are known to... 
Norepinephrine release | PTH-receptor | Chronic renal failure | Parathyroid hormone | Tuberoinfundibular peptide of 39 residues | PHYSIOLOGY | NORADRENALINE RELEASE | TUBEROINFUNDIBULAR PEPTIDE | SPONTANEOUSLY HYPERTENSIVE-RATS | PLASMA NOREPINEPHRINE | 39 RESIDUES | ENDOCRINOLOGY & METABOLISM | NITRIC-OXIDE | PARATHYROID-HORMONE | VASCULAR-RESISTANCE | CHRONIC-RENAL-FAILURE | SYMPATHETIC NEUROTRANSMISSION | Corticosterone - administration & dosage | Receptor, Parathyroid Hormone, Type 1 - antagonists & inhibitors | Corticosterone - pharmacology | Synaptic Transmission - physiology | Receptor, Parathyroid Hormone, Type 1 - metabolism | Humans | Middle Aged | Receptor, Parathyroid Hormone, Type 1 - agonists | Receptor, Parathyroid Hormone, Type 2 - metabolism | Receptor, Parathyroid Hormone, Type 2 - antagonists & inhibitors | Parathyroid Hormone - metabolism | Aged, 80 and over | Norepinephrine - secretion | Kidney - secretion | Peptide Fragments - metabolism | Cells, Cultured | Neuropeptides - metabolism | Receptor, Parathyroid Hormone, Type 2 - genetics | Cocaine - administration & dosage | Cocaine - pharmacology | Heart - secretion | Animals | Receptor, Parathyroid Hormone, Type 1 - genetics | Aged | Mice | Receptor, Parathyroid Hormone, Type 2 - agonists | Kidney Failure, Chronic - etiology | Kidney diseases | Peptides | Adenylic acid | Noradrenaline | Cardiac patients
Journal Article
Journal Article