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Genes & development, ISSN 0890-9369, 2008, Volume 22, Issue 10, pp. 1276 - 1312
Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as prototypes for growth factor and receptor tyrosine kinase function for more than 25 years... 
Development | PDGF receptor | Platelet-derived growth factor | Fibrosis | Cancer | development | platelet-derived growth factor | DEVELOPMENTAL BIOLOGY | FACTOR-B-CHAIN | FACTOR-RECEPTOR-BETA | CELL BIOLOGY | SIMIAN SARCOMA-VIRUS | GENETICS & HEREDITY | PDGF-ALPHA-RECEPTOR | FACTOR-A-CHAIN | TYROSINE KINASE INHIBITOR | cancer | fibrosis | SMOOTH-MUSCLE-CELLS | IDIOPATHIC HYPEREOSINOPHILIC SYNDROME | HEPARAN-SULFATE PROTEOGLYCANS | GASTROINTESTINAL STROMAL TUMORS | Receptors, Vascular Endothelial Growth Factor - physiology | Genetic Predisposition to Disease | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Embryo, Mammalian | Humans | Embryonic Development - genetics | Receptors, Platelet-Derived Growth Factor - genetics | Receptors, Platelet-Derived Growth Factor - physiology | Vascular Endothelial Growth Factor A - genetics | Platelet-Derived Growth Factor - genetics | Organogenesis | Disease - etiology | Tissue Distribution | Platelet-Derived Growth Factor - metabolism | Animals | Models, Biological | Signal Transduction - physiology | Polymorphism, Single Nucleotide | Receptors, Vascular Endothelial Growth Factor - genetics | Bone and Bones - embryology | Nervous System - embryology | Platelet-Derived Growth Factor - physiology | Vascular Endothelial Growth Factor A - physiology | Cardiovascular System - embryology | Tyrosine | Hematopoiesis | Pharmacology | Research | Chemical properties | Phosphotransferases | Health aspects | Review
Journal Article
FEBS Letters, ISSN 0014-5793, 03/2017, Volume 591, Issue 5, pp. 801 - 809
The platelet‐derived growth factor receptors alpha and beta (PDGFRα and PDGFRβ) mark fibroadipogenic progenitor cells/fibroblasts and pericytes in skeletal muscle, respectively... 
platelet‐derived growth factor | skeletal muscle | extracellular matrix | platelet-derived growth factor | TENDON | MESENCHYMAL PROGENITORS | CONNECTIVE-TISSUE FIBROBLASTS | REGENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISTINCT | INJURY | SATELLITE CELLS | BETA | CELL BIOLOGY | BIOPHYSICS | PDGFR-ALPHA | PERICYTES | Extracellular Matrix - metabolism | Muscle, Skeletal - metabolism | Gene Expression Profiling | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Hypertrophy - metabolism | Platelet-Derived Growth Factor - genetics | Quinolines - pharmacology | Hypertrophy - physiopathology | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Achilles Tendon - surgery | Receptor, Platelet-Derived Growth Factor alpha - antagonists & inhibitors | Muscle, Skeletal - drug effects | Hypertrophy - genetics | Receptor, Platelet-Derived Growth Factor beta - metabolism | Animals, Newborn | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Mice, Transgenic | Platelet-Derived Growth Factor - metabolism | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Muscle, Skeletal - physiopathology | Benzimidazoles - pharmacology | Weight-Bearing | Mice | Neovascularization, Physiologic
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 149, Issue 2, pp. 420 - 432.e16
Journal Article
American journal of physiology. Lung cellular and molecular physiology, ISSN 1522-1504, 2014, Volume 307, Issue 3, pp. L231 - L239
Animal studies have shown that platelet-derived growth factor (PDGF) signaling is required for normal alveolarization... 
PDGFR-β | Lung development | Prematurity | Hyperoxia | PDGFR-α | PDGFR-beta | CELLS | PHYSIOLOGY | prematurity | hyperoxia | PDGFR-alpha | ALPHA | MYOFIBROBLASTIC DIFFERENTIATION | CHRONIC LUNG-DISEASE | LAVAGE | RESPIRATORY SYSTEM | PDGF | TRANSFORMING GROWTH-FACTOR-BETA-1 | INFANTS | ALVEOLAR MACROPHAGES | lung development | MOUSE LUNG | Gene Expression - genetics | Humans | Bronchopulmonary Dysplasia - pathology | Male | Receptor, Platelet-Derived Growth Factor beta - genetics | Platelet-Derived Growth Factor - genetics | Bronchopulmonary Dysplasia - genetics | Infant, Premature - metabolism | Hyperoxia - metabolism | Pulmonary Alveoli - metabolism | Female | Lung - metabolism | Bronchopulmonary Dysplasia - etiology | Infant, Newborn | Receptor, Platelet-Derived Growth Factor beta - metabolism | Animals, Newborn | Lung - pathology | Pulmonary Alveoli - pathology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Mesenchymal Stromal Cells - metabolism | Signal Transduction - genetics | Gestational Age | Hyperoxia - pathology | Platelet-Derived Growth Factor - metabolism | Animals | Hyperoxia - genetics | Receptor, Platelet-Derived Growth Factor alpha - genetics | Mice | Mesenchymal Stromal Cells - pathology | Physiological aspects | Bronchopulmonary dysplasia | Platelet-derived growth factor
Journal Article
Journal Article
American journal of respiratory cell and molecular biology, ISSN 1535-4989, 2012, Volume 47, Issue 4, pp. 517 - 527
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, p. e0184473
Background Platelet-derived growth factor receptor alpha (PDGFR alpha) is a cell-surface receptor tyrosine kinase for platelet-derived growth factors... 
CRANIOFACIAL MUSCLES | PROTEASE-ACTIVATED LIGAND | MORPHOGENESIS | EVOLUTION | PDGF BETA-RECEPTOR | CELL-DEVELOPMENT | MULTIDISCIPLINARY SCIENCES | CARDIAC NEURAL CREST | TUBE DEFECTS | DEFICIENT MICE | MOUSE EMBRYO | Abnormalities, Multiple - metabolism | Immunohistochemistry | Cleft Lip - embryology | Spinal Dysraphism - genetics | Cleft Palate - genetics | Abnormalities, Multiple - embryology | Time Factors | Abdominal Wall - abnormalities | Gene Expression Regulation, Developmental | Spinal Dysraphism - embryology | Abnormalities, Multiple - genetics | Skeleton - metabolism | In Situ Nick-End Labeling | Hernia, Umbilical - embryology | Skeleton - abnormalities | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Mice, Inbred C57BL | Cleft Palate - embryology | Embryonic Development - physiology | Mice, Transgenic | Cleft Lip - metabolism | Gene Knockout Techniques | Tamoxifen | Hernia, Umbilical - metabolism | Cleft Lip - genetics | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Skeleton - embryology | Abdominal Wall - embryology | Cleft Palate - metabolism | Spinal Dysraphism - metabolism | Apoptosis - physiology | Hernia, Umbilical - genetics | Neonates | Pediatrics | Platelet-derived growth factor | Congenital defects | Mesoderm | Vertebra | Smooth muscle | Regulatory sequences | Kinases | Cell surface | Defects | Cell adhesion & migration | Proteins | Morphogenesis | Embryogenesis | Clonal deletion | Etiology | Rodents | Animal tissues | Surgery | Protein-tyrosine kinase receptors | Growth factors | Protein-tyrosine kinase | Endoderm | Tyrosine | Deformation mechanisms | Gene expression | Embryos | Embryonic growth stage | Medicine | Spina bifida | Congenital anomalies | Abdominal wall | Mice | Mutation | Apoptosis | Anomalies
Journal Article
International Journal of Cancer, ISSN 0020-7136, 02/2014, Volume 134, Issue 4, pp. 778 - 788
.... Hepatic expression of platelet‐derived growth factor C (PDGF‐C) induces progressive fibrosis, chronic inflammation, neoangiogenesis and sinusoidal congestion, as well as global changes in gene expression... 
stromal cell | microenvironment | PDGF | hepatocellular carcinoma | LIVER FIBROSIS | RECEPTOR | ALPHA | CLASSIFICATION | PDGF-C | MOUSE MODELS | ONCOLOGY | INFLAMMATION | GENE-EXPRESSION | APOPTOTIC BODIES | PROGRESSION | Inflammation - pathology | Liver - pathology | Oligonucleotide Array Sequence Analysis | Fatty Liver - pathology | Stromal Cells - pathology | Humans | Hepatic Stellate Cells - metabolism | Hepatocytes - pathology | Male | Gene Expression Profiling | Hepatocytes - metabolism | Platelet-Derived Growth Factor - genetics | Immunoenzyme Techniques | Inflammation - metabolism | Lymphokines - genetics | Carcinoma, Hepatocellular - genetics | Liver Cirrhosis - metabolism | Non-alcoholic Fatty Liver Disease | Biomarkers, Tumor - metabolism | Lymphokines - metabolism | Liver Neoplasms - pathology | Cytokines - genetics | Liver Cirrhosis - genetics | Real-Time Polymerase Chain Reaction | Hepatic Stellate Cells - pathology | Fatty Liver - genetics | Fatty Liver - metabolism | Cytokines - metabolism | Liver Neoplasms - genetics | Paracrine Communication | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Stromal Cells - metabolism | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Platelet-Derived Growth Factor - metabolism | Animals | Carcinoma, Hepatocellular - pathology | Fluorescent Antibody Technique | Liver Neoplasms - metabolism | Inflammation - genetics | Liver Cirrhosis - pathology | Biomarkers, Tumor - genetics | Mice | Carcinoma, Hepatocellular - metabolism | Cohort Studies | Immunohistochemistry | Platelet-derived growth factor | Analysis | Genetic engineering | Hepatoma | Gene expression | Liver cirrhosis | Liver cancer | Liver diseases | Transgenic animals | Growth factors | Rodents | Index Medicus
Journal Article
Nature neuroscience, ISSN 1546-1726, 2008, Volume 11, Issue 12, pp. 1392 - 1401
Platelet-derived growth factor a receptor (PDGFRA)/NG2-expressing glia are distributed throughout the adult CNS... 
PROGENITOR CELLS | STEM-CELLS | CORPUS-CALLOSUM | PDGF-ALPHA-RECEPTOR | SPINAL-CORD | SUBVENTRICULAR ZONE | RAT OPTIC-NERVE | CNS WHITE-MATTER | NG2-EXPRESSING CELLS | PRECURSOR CELLS | NEUROSCIENCES | Adult Stem Cells - physiology | Humans | Estrogen Antagonists - pharmacology | Phosphopyruvate Hydratase - metabolism | Cerebral Cortex - cytology | Neural Pathways - physiology | Luminescent Proteins - biosynthesis | Oligodendroglia - physiology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neurons - physiology | Bromodeoxyuridine - metabolism | Cell Differentiation - physiology | Adult Stem Cells - drug effects | Receptor, Fibroblast Growth Factor, Type 3 - genetics | Myelin Basic Protein - metabolism | Gene Expression Regulation - genetics | SOXE Transcription Factors - metabolism | RNA, Untranslated | Proteoglycans - metabolism | Mice, Transgenic | Antigens - metabolism | Oligodendrocyte Transcription Factor 2 | 2',3'-Cyclic-Nucleotide Phosphodiesterases - metabolism | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Proteins - genetics | Receptor, Platelet-Derived Growth Factor alpha - physiology | Animals | Proteins - metabolism | Cell Differentiation - drug effects | Receptor, Platelet-Derived Growth Factor alpha - genetics | Tamoxifen - pharmacology | Cerebral Cortex - physiology | Luminescent Proteins - genetics | Mice | Physiological aspects | Oligodendroglia | Myelination | Receptors | Research | Blood platelets
Journal Article
Allergy (Copenhagen), ISSN 0105-4538, 2016, Volume 71, Issue 6, pp. 803 - 810
...Imatinib, a tyrosine kinase inhibitor that selectively inhibits bcr‐abl , c‐kit, and the platelet‐derived growth factor receptor (PDGFR) tyrosine kinases... 
eosinophilia | imatinib | PDGFRA‐negative | hypereosinophilic syndrome | myeloid neoplasm | PDGFRA-negative | Hypereosinophilic Syndrome - drug therapy | Prognosis | Follow-Up Studies | Humans | Middle Aged | Male | Treatment Outcome | Young Adult |