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American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 07/2008, Volume 178, Issue 1, pp. 81 - 88
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 5/2007, Volume 177, Issue 3, pp. 489 - 500
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 1, pp. 118 - 122
Treatment of BRAF(V600E) mutant melanoma by small molecule drugs that target the BRAF or MEK kinases can be effective, but resistance develops invariably(1,2).... 
GROWTH-FACTOR RECEPTOR | BRAF INHIBITOR | RAF INHIBITION | CELLS | MULTIDISCIPLINARY SCIENCES | IMPROVED SURVIVAL | DIFFERENTIATION | C-JUN | CANCER | EXPRESSION | EGFR | Receptor, Epidermal Growth Factor - genetics | Humans | Receptor Protein-Tyrosine Kinases - biosynthesis | Cellular Senescence - drug effects | Melanoma - enzymology | Antineoplastic Agents - administration & dosage | Receptor, Platelet-Derived Growth Factor beta - genetics | Indoles - administration & dosage | Mitogen-Activated Protein Kinase Kinases - metabolism | Receptor, Epidermal Growth Factor - metabolism | Flow Cytometry | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | SOXE Transcription Factors - deficiency | Proto-Oncogene Proteins B-raf - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Epidermal Growth Factor - biosynthesis | Gene Library | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Transforming Growth Factor beta - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Signal Transduction - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Transforming Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor beta - biosynthesis | Sulfonamides - administration & dosage | Drug Resistance, Neoplasm - drug effects | SOXE Transcription Factors - genetics | Proteins | Biopsy | Rodents | Genes | Melanoma | Mutation | Kinases | Drug resistance | Patients | Tumors | Index Medicus
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 06/2012, Volume 26, Issue 11, pp. 1247 - 1262
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2013, Volume 19, Issue 8, pp. 1047 - 1053
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2012, Volume 18, Issue 11, pp. 1699 - 1704
Anaplastic large cell lymphoma (ALCL) is an aggressive non-Hodgkin's lymphoma found in children and young adults. ALCLs frequently carry a chromosomal... 
MEDICINE, RESEARCH & EXPERIMENTAL | FUSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | NEUROBLASTOMA | LARGE-CELL LYMPHOMA | CELL BIOLOGY | LUNG-CANCER | INHIBITION | GENE | HODGKIN LYMPHOMA | C-JUN | ACTIVATING MUTATIONS | Piperazines - administration & dosage | Translocation, Genetic | Protein-Tyrosine Kinases - metabolism | Transcription Factor AP-1 - genetics | Humans | Molecular Targeted Therapy | Receptor, Platelet-Derived Growth Factor beta - genetics | Transcription Factor AP-1 - metabolism | Stem Cell Transplantation | Protein-Tyrosine Kinases - genetics | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Receptor, Platelet-Derived Growth Factor alpha - antagonists & inhibitors | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Oncogene Protein p65(gag-jun) - genetics | Gene Expression Regulation, Neoplastic - drug effects | Nuclear Proteins - genetics | Lymphoma, Large-Cell, Anaplastic - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Pyrimidines - administration & dosage | Mice, Transgenic | Nuclear Proteins - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | Imatinib Mesylate | Remission Induction | Animals | Receptor Protein-Tyrosine Kinases - genetics | Receptor, Platelet-Derived Growth Factor alpha - genetics | Lymphoma, Large-Cell, Anaplastic - drug therapy | Cell Line, Tumor | Lymphoma, Large-Cell, Anaplastic - pathology | Mice | Benzamides | Neoplasm Staging | Oncogene Protein p65(gag-jun) - metabolism | Receptors | Blood platelets | Physiological aspects | Genetic aspects | Non-Hodgkin's lymphomas | Research | Drug therapy | Protein kinases | Therapy | Lymphomas | Cells | Cancer | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2014, Volume 289, Issue 28, pp. 19747 - 19757
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 2014, Volume 307, Issue 3, pp. L231 - L239
Animal studies have shown that platelet-derived growth factor (PDGF) signaling is required for normal alveolarization. Changes in PDGF receptor (PDGFR)... 
PDGFR-β | Lung development | Prematurity | Hyperoxia | PDGFR-α | PDGFR-beta | CELLS | PHYSIOLOGY | prematurity | hyperoxia | PDGFR-alpha | ALPHA | MYOFIBROBLASTIC DIFFERENTIATION | CHRONIC LUNG-DISEASE | LAVAGE | RESPIRATORY SYSTEM | PDGF | TRANSFORMING GROWTH-FACTOR-BETA-1 | INFANTS | ALVEOLAR MACROPHAGES | lung development | MOUSE LUNG | Gene Expression - genetics | Humans | Bronchopulmonary Dysplasia - pathology | Male | Receptor, Platelet-Derived Growth Factor beta - genetics | Platelet-Derived Growth Factor - genetics | Bronchopulmonary Dysplasia - genetics | Infant, Premature - metabolism | Hyperoxia - metabolism | Pulmonary Alveoli - metabolism | Female | Lung - metabolism | Bronchopulmonary Dysplasia - etiology | Infant, Newborn | Receptor, Platelet-Derived Growth Factor beta - metabolism | Animals, Newborn | Lung - pathology | Pulmonary Alveoli - pathology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Mesenchymal Stromal Cells - metabolism | Signal Transduction - genetics | Gestational Age | Hyperoxia - pathology | Platelet-Derived Growth Factor - metabolism | Animals | Hyperoxia - genetics | Receptor, Platelet-Derived Growth Factor alpha - genetics | Mice | Mesenchymal Stromal Cells - pathology | Physiological aspects | Bronchopulmonary dysplasia | Platelet-derived growth factor | Babies | Lungs | Ribonucleic acid--RNA | Gene expression | Rodents | Cells | Index Medicus
Journal Article