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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2010, Volume 107, Issue 25, pp. 11307 - 11312
Journal Article
Genes & development, ISSN 0890-9369, 2008, Volume 22, Issue 10, pp. 1276 - 1312
Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as prototypes for growth factor and receptor tyrosine kinase function for more than 25 years... 
Development | PDGF receptor | Platelet-derived growth factor | Fibrosis | Cancer | development | platelet-derived growth factor | DEVELOPMENTAL BIOLOGY | FACTOR-B-CHAIN | FACTOR-RECEPTOR-BETA | CELL BIOLOGY | SIMIAN SARCOMA-VIRUS | GENETICS & HEREDITY | PDGF-ALPHA-RECEPTOR | FACTOR-A-CHAIN | TYROSINE KINASE INHIBITOR | cancer | fibrosis | SMOOTH-MUSCLE-CELLS | IDIOPATHIC HYPEREOSINOPHILIC SYNDROME | HEPARAN-SULFATE PROTEOGLYCANS | GASTROINTESTINAL STROMAL TUMORS | Receptors, Vascular Endothelial Growth Factor - physiology | Genetic Predisposition to Disease | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Embryo, Mammalian | Humans | Embryonic Development - genetics | Receptors, Platelet-Derived Growth Factor - genetics | Receptors, Platelet-Derived Growth Factor - physiology | Vascular Endothelial Growth Factor A - genetics | Platelet-Derived Growth Factor - genetics | Organogenesis | Disease - etiology | Tissue Distribution | Platelet-Derived Growth Factor - metabolism | Animals | Models, Biological | Signal Transduction - physiology | Polymorphism, Single Nucleotide | Receptors, Vascular Endothelial Growth Factor - genetics | Bone and Bones - embryology | Nervous System - embryology | Platelet-Derived Growth Factor - physiology | Vascular Endothelial Growth Factor A - physiology | Cardiovascular System - embryology | Tyrosine | Hematopoiesis | Pharmacology | Research | Chemical properties | Phosphotransferases | Health aspects | Review
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2016, Volume 186, Issue 7, pp. 1890 - 1899
.... Thus, novel therapeutic targets are needed urgently. We have observed in a laser-induced model of CNV that a platelet-derived growth factor receptor β positive (PDGFRβ... 
Pathology | VEGF | THERAPY | PATHOLOGY | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Animals | Choroidal Neovascularization - metabolism | Choroidal Neovascularization - pathology | Mice, Inbred C57BL | Pericytes - metabolism | Male | Mice, Transgenic | Mice | Disease Models, Animal
Journal Article
FEBS Letters, ISSN 0014-5793, 03/2017, Volume 591, Issue 5, pp. 801 - 809
The platelet‐derived growth factor receptors alpha and beta (PDGFRα and PDGFRβ) mark fibroadipogenic progenitor cells/fibroblasts and pericytes in skeletal muscle, respectively... 
platelet‐derived growth factor | skeletal muscle | extracellular matrix | platelet-derived growth factor | TENDON | MESENCHYMAL PROGENITORS | CONNECTIVE-TISSUE FIBROBLASTS | REGENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISTINCT | INJURY | SATELLITE CELLS | BETA | CELL BIOLOGY | BIOPHYSICS | PDGFR-ALPHA | PERICYTES | Extracellular Matrix - metabolism | Muscle, Skeletal - metabolism | Gene Expression Profiling | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Hypertrophy - metabolism | Platelet-Derived Growth Factor - genetics | Quinolines - pharmacology | Hypertrophy - physiopathology | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Achilles Tendon - surgery | Receptor, Platelet-Derived Growth Factor alpha - antagonists & inhibitors | Muscle, Skeletal - drug effects | Hypertrophy - genetics | Receptor, Platelet-Derived Growth Factor beta - metabolism | Animals, Newborn | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Mice, Transgenic | Platelet-Derived Growth Factor - metabolism | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Muscle, Skeletal - physiopathology | Benzimidazoles - pharmacology | Weight-Bearing | Mice | Neovascularization, Physiologic
Journal Article
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 04/2015, Volume 290, Issue 15, pp. 9738 - 9752
Journal Article
American journal of physiology. Lung cellular and molecular physiology, ISSN 1522-1504, 2014, Volume 307, Issue 3, pp. L231 - L239
Animal studies have shown that platelet-derived growth factor (PDGF) signaling is required for normal alveolarization... 
PDGFR-β | Lung development | Prematurity | Hyperoxia | PDGFR-α | PDGFR-beta | CELLS | PHYSIOLOGY | prematurity | hyperoxia | PDGFR-alpha | ALPHA | MYOFIBROBLASTIC DIFFERENTIATION | CHRONIC LUNG-DISEASE | LAVAGE | RESPIRATORY SYSTEM | PDGF | TRANSFORMING GROWTH-FACTOR-BETA-1 | INFANTS | ALVEOLAR MACROPHAGES | lung development | MOUSE LUNG | Gene Expression - genetics | Humans | Bronchopulmonary Dysplasia - pathology | Male | Receptor, Platelet-Derived Growth Factor beta - genetics | Platelet-Derived Growth Factor - genetics | Bronchopulmonary Dysplasia - genetics | Infant, Premature - metabolism | Hyperoxia - metabolism | Pulmonary Alveoli - metabolism | Female | Lung - metabolism | Bronchopulmonary Dysplasia - etiology | Infant, Newborn | Receptor, Platelet-Derived Growth Factor beta - metabolism | Animals, Newborn | Lung - pathology | Pulmonary Alveoli - pathology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Mesenchymal Stromal Cells - metabolism | Signal Transduction - genetics | Gestational Age | Hyperoxia - pathology | Platelet-Derived Growth Factor - metabolism | Animals | Hyperoxia - genetics | Receptor, Platelet-Derived Growth Factor alpha - genetics | Mice | Mesenchymal Stromal Cells - pathology | Physiological aspects | Bronchopulmonary dysplasia | Platelet-derived growth factor
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e67581
...). In this study, we found that miR-34a and miR-34c target platelet-derived growth factor receptor alpha and beta... 
INVASION | RECEPTOR-TYROSINE-KINASES | COLORECTAL-CANCER | POOR-PROGNOSIS | MULTIDISCIPLINARY SCIENCES | TUMOR | TARGETS | GROWTH-FACTOR | MUTATIONS | EXPRESSION | BETA | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | MicroRNAs - metabolism | TNF-Related Apoptosis-Inducing Ligand - toxicity | RNA, Messenger - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | RNA Interference | Receptor, Platelet-Derived Growth Factor alpha - antagonists & inhibitors | Base Sequence | Lung - metabolism | 3' Untranslated Regions | Receptor, Platelet-Derived Growth Factor beta - metabolism | Lung - pathology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Down-Regulation - drug effects | Carcinogenesis - drug effects | Sequence Alignment | Receptor, Platelet-Derived Growth Factor alpha - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | MicroRNAs - genetics | Cell Movement | RNA, Small Interfering - metabolism | Platelet-derived growth factor | Lung cancer | Critical care | Malignancy | Metastasis | Kinases | Tissues | Cell surface | Signal transduction | Receptors | Immunology | miRNA | Tumorigenesis | Growth factors | Protein-tyrosine kinase | Tyrosine | Invasiveness | Non-small cell lung carcinoma | Gene expression | Virology | Tumor necrosis factor | MicroRNAs | Medical prognosis | Tumor suppressor genes | Ligands | TRAIL protein | Mutation | Health risk assessment | Cell migration | Tumors | Cancer | Apoptosis
Journal Article