Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (940) 940
animals (911) 911
life sciences & biomedicine (864) 864
humans (587) 587
male (461) 461
serotonin (420) 420
pharmacology & pharmacy (375) 375
rats (370) 370
neurosciences (321) 321
neurosciences & neurology (305) 305
biological and medical sciences (295) 295
receptors, serotonin - metabolism (260) 260
mice (258) 258
medical sciences (223) 223
serotonin antagonists - pharmacology (212) 212
receptor, serotonin, 5-ht2b - metabolism (198) 198
5-ht (196) 196
serotonin receptor agonists - pharmacology (193) 193
rats, sprague-dawley (187) 187
serotonin - metabolism (187) 187
female (163) 163
receptors (156) 156
dose-response relationship, drug (144) 144
pharmacology. drug treatments (135) 135
serotonin - pharmacology (128) 128
psychiatry (126) 126
signal transduction (111) 111
indoles - pharmacology (108) 108
receptor, serotonin, 5-ht2b (108) 108
biochemistry & molecular biology (104) 104
receptors, serotonin - drug effects (103) 103
rats, wistar (101) 101
receptor, serotonin, 5-ht2a - metabolism (100) 100
receptor (98) 98
fundamental and applied biological sciences. psychology (97) 97
cells, cultured (93) 93
neurology (91) 91
ligands (90) 90
rodents (90) 90
gene expression (85) 85
neuropharmacology (83) 83
phenols (81) 81
research (81) 81
serotonin receptors (81) 81
pharmacology (79) 79
receptor, serotonin, 5-ht2b - genetics (79) 79
receptor, serotonin, 5-ht2c - metabolism (79) 79
cell biology (77) 77
proteins (77) 77
brain - metabolism (76) 76
disease models, animal (75) 75
mice, inbred c57bl (75) 75
multidisciplinary sciences (75) 75
science & technology - other topics (75) 75
receptors, serotonin - genetics (74) 74
cell line (73) 73
serotonin s2 receptors (73) 73
in vitro techniques (72) 72
dopamine (71) 71
clinical neurology (70) 70
piperazines - pharmacology (70) 70
life sciences (69) 69
mice, knockout (68) 68
structure-activity relationship (68) 68
research article (67) 67
psychology. psychoanalysis. psychiatry (66) 66
receptors, serotonin - physiology (65) 65
serotonin 5-ht2 receptor antagonists - pharmacology (65) 65
physiological aspects (64) 64
physiology (64) 64
serotonin - physiology (63) 63
serotonin 5-ht2 receptor antagonists (63) 63
analysis (62) 62
neurons (62) 62
medicine (60) 60
time factors (59) 59
chemistry, medicinal (58) 58
receptor, serotonin, 5-ht2c (58) 58
brain (57) 57
chemistry (56) 56
cricetinae (55) 55
receptor, serotonin, 5-ht2a (55) 55
physical sciences (54) 54
adult (53) 53
biology (53) 53
protein binding (53) 53
serotonin 5-ht2 receptor agonists (53) 53
serotonin 5-ht2 receptor agonists - pharmacology (52) 52
signal transduction - drug effects (52) 52
psychopharmacology (51) 51
receptors, g-protein-coupled - metabolism (51) 51
binding sites (50) 50
biomedicine (50) 50
nervous system (50) 50
radioligand assay (50) 50
schizophrenia (50) 50
calcium - metabolism (49) 49
cho cells (49) 49
vertebrates: nervous system and sense organs (49) 49
internal medicine (48) 48
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1237) 1237
Russian (10) 10
Japanese (6) 6
French (4) 4
Chinese (1) 1
German (1) 1
Norwegian (1) 1
Portuguese (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
by Ebrahimkhani, Mohammad R and Oakley, Fiona and Murphy, Lindsay B and Mann, Jelena and Moles, Anna and Perugorria, Maria J and Ellis, Elizabeth and Lakey, Anne F and Burt, Alastair D and Douglass, Angela and Wright, Matthew C and White, Steven A and Jaffre, Fabrice and Maroteaux, Luc and Mann, Derek A
Nature medicine, ISSN 1078-8956, 12/2011, Volume 17, Issue 12, pp. 1668 - U189
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Immunohistochemistry | Receptor, Serotonin, 5-HT2B - metabolism | Transforming Growth Factor beta1 - metabolism | Hepatic Stellate Cells - metabolism | Male | Wound Healing | Serotonin - pharmacology | Hepatocytes - cytology | Receptor, Serotonin, 5-HT2B - drug effects | Mitogen-Activated Protein Kinase 1 - genetics | Urea - analogs & derivatives | Indoles - pharmacology | Hepatocytes - drug effects | Hepatic Stellate Cells - drug effects | Signal Transduction | Proto-Oncogene Proteins c-jun - genetics | Electrophoresis, Polyacrylamide Gel | Mice, Inbred C57BL | Cells, Cultured | Rats | Liver Cirrhosis - therapy | Transforming Growth Factor beta1 - genetics | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Rats, Sprague-Dawley | Mice, Knockout | Animals | Proto-Oncogene Proteins c-jun - metabolism | Liver Cirrhosis - pathology | Cell Proliferation - drug effects | Mice | Chronic Disease | Urea - pharmacology | Mitogen-Activated Protein Kinase 1 - metabolism | Proteins | Signal transduction | Cell growth | Liver diseases | Gene expression | Chronic illnesses | Index Medicus | Cell Proliferation | Serotonin 5-HT2 Receptor Antagonists | Life Sciences | Indoles | Transforming Growth Factor beta1 | Serotonin | Biochemistry, Molecular Biology | Liver Cirrhosis | Receptor, Serotonin, 5-HT2B | Urea | Hepatocytes | Hepatic Stellate Cells | Mitogen-Activated Protein Kinase 1 | Proto-Oncogene Proteins c-jun
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text 5-HT2B receptors are required for serotonin-selective antidepressant actions
by Diaz, S. L and Doly, S and Narboux-Neme, N and Fernandez, S and Mazot, P and Banas, S. M and Boutourlinsky, K and Moutkine, I and Belmer, A and Roumier, A and Maroteaux, L
Molecular psychiatry, ISSN 1359-4184, 02/2012, Volume 17, Issue 2, pp. 154 - 163
Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer | Psychology. Psychoanalysis. Psychiatry | Psychopharmacology | Pharmacology. Drug treatments | Psychopathology. Psychiatry | Biological and medical sciences | Medical sciences | Neuropharmacology | Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) | 5-HT2B receptors | Bromodeoxyuridine | Male | Reaction Time | Serotonin Plasma Membrane Transport Proteins | Chromatography, High Pressure Liquid | Neurogenesis | Time Factors | Ki-67 Antigen | pharmacology | Cell Differentiation | Exploratory Behavior | chemically induced | Serotonin | Fluoxetine | Mice, Inbred C57BL | Serotonin Receptor Agonists | Gene Expression Regulation | physiology | serotonin levels | drug effects | antidepressants | Receptor, Serotonin, 5-HT2B | Mice, Knockout | Animals | Microdialysis | Analysis of Variance | deficiency | 8-Hydroxy-2-(di-n-propylamino)tetralin | adverse effects | metabolism | Mice | Transcription Factors | Hippocampus | Hypothermia | Serotonin Uptake Inhibitors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text BF-1 – A novel selective 5-HT2B receptor antagonist blocking neurogenic dural plasma protein extravasation in guinea pigs
by Schmitz, Beate and Ullmer, Christoph and Segelcke, Daniel and Gwarek, Mirella and Zhu, Xin-Ran and Lübbert, Hermann
European journal of pharmacology, ISSN 0014-2999, 03/2015, Volume 751, pp. 73 - 80
5-HT2B receptor | Antagonist BF-1 | 5-HT | receptor | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cell Line | Guinea Pigs | Piperidines - metabolism | Receptor, Serotonin, 5-HT2B - metabolism | Thioxanthenes - metabolism | Humans | Substrate Specificity | Thiophenes - pharmacology | Male | Blood Proteins - metabolism | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Piperazines - pharmacology | Serotonin 5-HT2 Receptor Antagonists - metabolism | Brain - drug effects | Brain - metabolism | Thioxanthenes - pharmacology | Animals | Piperidines - pharmacology | Xanthenes - metabolism | Indoles - pharmacology | Xanthenes - pharmacology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Serotonin receptor 5-HT2B mediates serotonin-induced mechanical hyperalgesia
by Lin, Shih-Yuan and Chang, Wei-Jen and Lin, Chih-Shin and Huang, Chun-Ying and Wang, Hui-Fang and Sun, Wei-Hsin
The Journal of neuroscience, ISSN 0270-6474, 01/2011, Volume 31, Issue 4, pp. 1410 - 1418
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cell Line | Serotonin - physiology | Humans | Receptor, Serotonin, 5-HT2C - metabolism | Male | Hot Temperature | Serotonin - pharmacology | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Touch | Mice, Inbred ICR | Hyperalgesia - physiopathology | Receptor, Serotonin, 5-HT2B - physiology | Animals | Calcium Signaling - drug effects | Indoles - pharmacology | Mice | Neurons - metabolism | Nociceptors - metabolism | Pyridines - pharmacology | Ganglia, Spinal - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Transient, 5-HT2B receptor–mediated facilitation in neuropathic pain: Up-regulation of PKCγ and engagement of the NMDA receptor in dorsal horn neurons
by Aira, Zigor and Buesa, Itsaso and García del Caño, Gontzal and Bilbao, Juan and Doñate, Francisco and Zimmermann, Manfred and Azkue, Jon Jatsu
Pain (Amsterdam), ISSN 0304-3959, 09/2013, Volume 154, Issue 9, pp. 1865 - 1877
Electrophysiology | Serotonin | Evoked potentials | Synaptic plasticity | Neuropathic pain | Neurosciences | Clinical Neurology | Anesthesiology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Neurology | Nervous system involvement in other diseases. Miscellaneous | Biological and medical sciences | Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors | Medical sciences | Receptor, Serotonin, 5-HT2B - metabolism | Humans | Neuralgia - metabolism | Male | Neuralgia - pathology | Serotonin Receptor Agonists - pharmacology | Dose-Response Relationship, Drug | Time Factors | Protein Kinase C - metabolism | Up-Regulation - physiology | HEK293 Cells | Nerve Fibers, Unmyelinated - drug effects | Indoles - pharmacology | Neurons - metabolism | Spinal Nerves | Disease Models, Animal | Physical Stimulation | Nerve Fibers, Unmyelinated - physiology | Subcellular Fractions - drug effects | Enzyme Inhibitors - pharmacology | Rats | Thiophenes - pharmacology | Receptors, N-Methyl-D-Aspartate | Excitatory Amino Acid Antagonists - pharmacology | Rats, Sprague-Dawley | Subcellular Fractions - metabolism | Hyperalgesia - physiopathology | Evoked Potentials - drug effects | Up-Regulation - drug effects | Animals | Spinal Nerve Roots - pathology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Serotonin 5-HT2B Receptors Are Required for 3,4-Methylenedioxymethamphetamine-Induced Hyperlocomotion and 5-HT Release In Vivo and In Vitro
by Doly, Stephane and Valjent, Emmanuel and Setola, Vincent and Callebert, Jacques and Herve, Denis and Launay, Jean-Marie and Maroteaux, Luc
The Journal of neuroscience, ISSN 0270-6474, 03/2008, Volume 28, Issue 11, pp. 2933 - 2940
Microdialysis | Behavior | Synaptosomes | 5-HT | Serotonin release | MDMA | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Receptor, Serotonin, 5-HT2B - metabolism | Male | Hyperkinesis - metabolism | Serotonin Antagonists - pharmacology | Serotonin 5-HT2 Receptor Antagonists | Animals | N-Methyl-3,4-methylenedioxyamphetamine - pharmacology | Mice, Mutant Strains | Protein Binding - drug effects | Serotonin - metabolism | Female | Hyperkinesis - chemically induced | Mice | N-Methyl-3,4-methylenedioxyamphetamine - toxicity | Protein Binding - physiology | Index Medicus | Serotonin | Biochemistry, Molecular Biology | Hyperkinesis | Receptor, Serotonin, 5-HT2B | Life Sciences | Serotonin Antagonists | N-Methyl-3,4-methylenedioxyamphetamine | Protein Binding | 5-HT2B | serotonin release | microdialysis | behavior | synaptosomes
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Multidimensional De Novo Design Reveals 5‐HT2B Receptor‐Selective Ligands
by Rodrigues, Tiago and Hauser, Nadine and Reker, Daniel and Reutlinger, Michael and Wunderlin, Tiffany and Hamon, Jacques and Koch, Guido and Schneider, Gisbert
Angewandte Chemie (International ed.), ISSN 1433-7851, 01/2015, Volume 54, Issue 5, pp. 1551 - 1555
GPCR | drug discovery | organic synthesis | microfluidics | computer‐assisted molecular design | Organic synthesis | Drug discovery | Computer-assisted molecular design | Microfluidics | Amines - chemistry | Receptor, Serotonin, 5-HT2B - chemistry | Receptor, Serotonin, 5-HT2B - metabolism | Humans | Drug Design | Protein Binding | Ligands | Amines - chemical synthesis | Computer-Aided Design | Serotonin 5-HT2 Receptor Antagonists - chemistry | Serotonin 5-HT2 Receptor Antagonists - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Serotonin 5-HT2B Receptor-Stimulated DNA Synthesis and Proliferation Are Mediated by Autocrine Secretion of Transforming Growth Factor-α in Primary Cultures of Adult Rat Hepatocytes
by Naito, Kota and Moteki, Hajime and Kimura, Mitsutoshi and Natsume, Hideshi and Ogihara, Masahiko
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2016, Volume 39, Issue 4, pp. 570 - 577
transforming growth factor (TGF)-α | serotonin (5-HT) | 5-HT2B receptor | signal transduction | autocrine secretion (cultured hepatocyte) | Autocrine secretion (cultured hepatocyte) | Signal transduction | Transforming growth factor (TGF)-α | receptor | 5-HT | Serotonin (5-HT) | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Rats, Wistar | Receptor, Serotonin, 5-HT2B - metabolism | Cells, Cultured | Thiophenes - pharmacology | Male | Serotonin 5-HT2 Receptor Agonists - pharmacology | DNA - metabolism | Hepatocytes - metabolism | Serotonin - pharmacology | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Type C Phospholipases - antagonists & inhibitors | Animals | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Organic Chemicals - pharmacology | Indoles - pharmacology | Cell Proliferation - drug effects | Transforming Growth Factor alpha - metabolism | Hepatocytes - drug effects | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Serotonin is a novel survival factor of cardiomyocytes: mitochondria as a target of 5‐HT2B‐receptor signaling
by Nebigil, Canan G and Etienne, Nelly and Messaddeq, Nadia and Maroteaux, Luc
The FASEB journal, ISSN 0892-6638, 07/2003, Volume 17, Issue 10, pp. 1373 - 1375
Bax | Gq | Akt | PI3 kinase | ERK | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Mitochondria, Heart - ultrastructure | Mitochondria, Heart - metabolism | Protein-Serine-Threonine Kinases | Culture Media, Serum-Free | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Serotonin - pharmacology | Caspases - metabolism | Cytoprotection | Proto-Oncogene Proteins - metabolism | Myocytes, Cardiac - cytology | Signal Transduction | Cell Survival | Cells, Cultured | Adenine Nucleotide Translocator 1 - metabolism | bcl-2-Associated X Protein | Receptor, Serotonin, 5-HT2B | Cytochrome c Group - metabolism | Receptors, Serotonin - metabolism | Mice, Knockout | Proto-Oncogene Proteins c-akt | Animals | Cardiomyopathy, Dilated - etiology | Mitochondria, Heart - physiology | Myocytes, Cardiac - metabolism | Mice | Proto-Oncogene Proteins c-bcl-2 | Myocytes, Cardiac - ultrastructure | Apoptosis | Mitogen-Activated Protein Kinases - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Synthesis and structure–activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists. Part 2
by Moritomo, Ayako and Yamada, Hiroyoshi and Watanabe, Toshihiro and Itahana, Hirotsune and Koga, Yuji and Akuzawa, Shinobu and Okada, Minoru
Bioorganic & medicinal chemistry, ISSN 0968-0896, 08/2014, Volume 22, Issue 15, pp. 4323 - 4337
5-HT7 receptor | Docking study | Carbonyl guanidine | Dual antagonist | 5-HT2B receptor | Migraine | Cricetulus | Body Temperature - drug effects | Receptor, Serotonin, 5-HT2B - metabolism | Humans | Male | Serotonin Antagonists - chemical synthesis | Structure-Activity Relationship | Receptors, Serotonin - genetics | Serotonin - pharmacology | Receptor, Serotonin, 5-HT2B - genetics | Guanidine - chemical synthesis | Serotonin Antagonists - chemistry | HEK293 Cells | Binding Sites | CHO Cells | Protein Structure, Tertiary | Serotonin Antagonists - pharmacokinetics | Cricetinae | Guinea Pigs | Administration, Oral | Guanidine - analogs & derivatives | Receptors, Serotonin - chemistry | Receptors, Serotonin - metabolism | Receptor, Serotonin, 5-HT2B - chemistry | Animals | Hypothermia, Induced | Protein Binding | Serotonin - analogs & derivatives | Mice | Molecular Docking Simulation | Guanidine - pharmacokinetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension
by Launay, Jean-Marie and Herve, Philippe and Callebert, Jacques and Mallat, Ziad and Collet, Corinne and Doly, Stephane and Belmer, Arnauld and Diaz, Silvina L and Hatia, Sarah and Cote, Francine and Humbert, Marc and Maroteaux, Luc
Blood, ISSN 0006-4971, 02/2012, Volume 119, Issue 7, pp. 1772 - 1780
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Biological and medical sciences | Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases | Medical sciences | Pneumology | Blood Chemical Analysis | Receptor, Serotonin, 5-HT2B - metabolism | Humans | Bone Marrow Cells - physiology | Male | Hypertension, Pulmonary - blood | Bone Marrow - physiology | Proto-Oncogene Proteins c-kit - metabolism | Blood - metabolism | Receptor, Serotonin, 5-HT2B - physiology | Cell Differentiation - genetics | Receptor, Serotonin, 5-HT2B - genetics | Bone Marrow - metabolism | Female | Proto-Oncogene Proteins c-kit - genetics | Lung - metabolism | Cells, Cultured | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary - genetics | Hypertension, Pulmonary - immunology | Hypertension, Pulmonary - metabolism | Mice, Knockout | Animals | Models, Biological | Mice | Bone Marrow Cells - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights