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1. Full Text MicroRNA‐150 regulates blood‐brain barrier permeability via Tie‐2 after permanent middle cerebral artery occlusion in rats
by Fang, Zhi and He, Quan‐Wei and Li, Qian and Chen, Xiao‐Lu and Baral, Suraj and Jin, Hui‐Juan and Zhu, Yi‐Yi and Li, Man and Xia, Yuan‐Peng and Mao, Ling and Hu, Bo
The FASEB journal, ISSN 0892-6638, 06/2016, Volume 30, Issue 6, pp. 2097 - 2107
apoptosis | BMEC | claudin‐5 | ischemic stroke | Claudin-5 | Ischemic stroke | Apoptosis | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Up-Regulation | Claudin-5 - metabolism | Rats | Claudin-5 - genetics | MicroRNAs - metabolism | Middle Cerebral Artery - pathology | Permeability | Infarction, Middle Cerebral Artery - metabolism | Receptor, TIE-2 - genetics | Animals | Blood-Brain Barrier - physiology | Receptor, TIE-2 - metabolism | MicroRNAs - genetics | Endothelial Cells - physiology | Index Medicus
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2. Full Text Dysregulation of the angiopoietin-Tie-2 axis in sepsis and ARDS
by Parikh, Samir M
Virulence, ISSN 2150-5594, 08/2013, Volume 4, Issue 6, pp. 517 - 524
angiopoietin-2 | angiopoietin-1 | vascular leakage | infection | Tie-1 | Tie-2 | VE-cadherin | permeability | acute respiratory distress syndrome | VE-PTP | sepsis | Acute respiratory distress syndrome | Infection | Angiopoietin-1 | Angiopoietin-2 | Sepsis | Permeability | Vascular leakage | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Respiratory Distress Syndrome, Adult - physiopathology | Angiopoietin-2 - genetics | Humans | Endothelium, Vascular - physiopathology | Angiopoietin-1 - metabolism | Respiratory Distress Syndrome, Adult - metabolism | Sepsis - physiopathology | Angiopoietin-2 - metabolism | Sepsis - genetics | Receptor, TIE-2 - genetics | Angiopoietin-1 - genetics | Respiratory Distress Syndrome, Adult - genetics | Animals | Endothelium, Vascular - metabolism | Sepsis - metabolism | Receptor, TIE-2 - metabolism | Index Medicus
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3. Full Text VE-PTP Controls Blood Vessel Development by Balancing Tie-2 Activity
by Mark Winderlich and Linda Keller and Giuseppe Cagna and Andre Broermann and Olena Kamenyeva and Friedemann Kiefer and Urban Deutsch and Astrid F. Nottebaum and Dietmar Vestweber
The Journal of cell biology, ISSN 0021-9525, 5/2009, Volume 185, Issue 4, pp. 657 - 671
Phosphorylation | Receptors | Phosphatases | Antibodies | Blood vessels | Small interfering RNA | Allantois | Cellular immunity | Endothelial cells | Renovations | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Endothelium, Vascular - cytology | Blood Vessels - growth & development | Receptor-Like Protein Tyrosine Phosphatases, Class 3 - physiology | Cell Proliferation | Cadherins - metabolism | Embryo, Mammalian - blood supply | Humans | Cells, Cultured | Antigens, CD - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Receptor, TIE-2 - metabolism | Mice | Physiological aspects | Cell receptors | Genetic aspects | Research | Proteins | Amino acids | Embryos | Rodents | Cells | Index Medicus
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4. Full Text Expression of Tie-2 by Human Monocytes and Their Responses to Angiopoietin-2
by Murdoch, Craig and Tazzyman, Simon and Webster, Steve and Lewis, Claire E
The Journal of immunology (1950), ISSN 0022-1767, 06/2007, Volume 178, Issue 11, pp. 7405 - 7411
Life Sciences & Biomedicine | Immunology | Science & Technology | Cell Hypoxia - immunology | Humans | Neoplasms, Experimental - enzymology | Monocytes - metabolism | Neoplasms, Experimental - pathology | Lymphocyte Subsets - metabolism | RNA, Messenger - biosynthesis | Cell Membrane - pathology | Monocytes - pathology | Angiopoietin-2 - physiology | Granulocytes - pathology | Neovascularization, Pathologic - immunology | Granulocytes - metabolism | Receptor, TIE-2 - physiology | Inflammation Mediators - physiology | Lymphocyte Subsets - pathology | Cytokines - metabolism | Macrophages - pathology | Gene Expression Regulation - immunology | RNA, Messenger - genetics | Receptor, TIE-2 - biosynthesis | Cells, Cultured | Granulocytes - enzymology | Macrophages - enzymology | Receptor, TIE-2 - genetics | Cell Membrane - enzymology | Monocytes - enzymology | Macrophages - metabolism | Animals | Up-Regulation - immunology | Lymphocyte Subsets - enzymology | Cell Membrane - immunology | Mice | Cytokines - antagonists & inhibitors | Chemotaxis, Leukocyte - immunology | Neoplasms, Experimental - blood supply | Index Medicus | Abridged Index Medicus
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5. Full Text Autocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal
by Abou-Khalil, Rana and Le Grand, Fabien and Pallafacchina, Giorgia and Valable, Samuel and Authier, François-Jérôme and Rudnicki, Michael A and Gherardi, Romain K and Germain, Stéphane and Chretien, Fabrice and Sotiropoulos, Athanassia and Lafuste, Peggy and Montarras, Didier and Chazaud, Bénédicte
Cell stem cell, ISSN 1934-5909, 2009, Volume 5, Issue 3, pp. 298 - 309
STEMCELL | Cell & Tissue Engineering | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell differentiation, maturation, development, hematopoiesis | Gene Silencing - drug effects | Apoptosis - drug effects | Cell Count | Humans | Autocrine Communication - drug effects | PAX7 Transcription Factor - metabolism | Stem Cells - cytology | Angiopoietin-1 - metabolism | Stem Cells - metabolism | Protein Binding - drug effects | Receptor, TIE-2 - metabolism | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Angiopoietin-1 - pharmacology | Fibroblasts - metabolism | Satellite Cells, Skeletal Muscle - cytology | Cells, Cultured | Satellite Cells, Skeletal Muscle - metabolism | Satellite Cells, Skeletal Muscle - drug effects | Satellite Cells, Skeletal Muscle - enzymology | Animals | Muscle Development - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Fibroblasts - drug effects | Paracrine Communication - drug effects | Stem Cells - drug effects | Cell Proliferation - drug effects | Mice | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus
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6. Full Text The Tie-2 ligand Angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies
by Fiedler, Ulrike and Scharpfenecker, Marion and Koidl, Stefanie and Hegen, Anja and Grunow, Verena and Schmidt, Jarno M and Kriz, Wilhelm and Thurston, Gavin and Augustin, Hellmut G
Blood, ISSN 0006-4971, 06/2004, Volume 103, Issue 11, pp. 4150 - 4156
Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Blood vessels and receptors | Vertebrates: cardiovascular system | Endothelium, Vascular - cytology | Gene Expression | Tetradecanoylphorbol Acetate - pharmacology | P-Selectin - metabolism | Angiopoietin-2 - genetics | Humans | Cells, Cultured | Endothelium, Vascular - drug effects | Muscle, Smooth, Vascular - cytology | Angiopoietin-2 - metabolism | Carcinogens - pharmacology | Weibel-Palade Bodies - metabolism | Endothelium, Vascular - metabolism | Umbilical Arteries - cytology | Ligands | Receptor, TIE-2 - metabolism | Umbilical Veins - cytology | Index Medicus | Abridged Index Medicus
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7. Full Text Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality
by Sascha David and Chandra C. Ghosh and Philipp Kümpers and Nelli Shushakova and Paul Van Slyke and Eliyahu V. Khankin and S. Ananth Karumanchi and Dan Dumont and Samir M. Parikh
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 06/2011, Volume 300, Issue 6, pp. 851 - 862
Acute lung injury | Vasculotide | Tie-2/TEK | Angiopoietins | Sepsis | Endothelial permeability | Vascular leakage | Endotoxin | Respiratory System | Physiology | Life Sciences & Biomedicine | Science & Technology | Endothelium, Vascular - cytology | Endotoxemia - prevention & control | Humans | Capillary Permeability - drug effects | Endotoxemia - chemically induced | Endothelium, Vascular - drug effects | Male | Peptide Fragments - pharmacology | Polyethylene Glycols - chemistry | Immunoenzyme Techniques | Lung Injury - mortality | Lung Injury - prevention & control | Polyethylene Glycols - metabolism | Receptor, TIE-2 - agonists | Mice, Inbred C57BL | RNA, Messenger - genetics | Survival Rate | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Polyethylene Glycols - administration & dosage | Peptide Fragments - chemical synthesis | Animals | Lipopolysaccharides - pharmacology | Mice | Endotoxemia - mortality | Lung Injury - chemically induced | Endotoxins - adverse effects | Physiological aspects | Care and treatment | Angiogenin | Health aspects | Lung diseases | Angiogenesis | Peptides | Mortality | Rodents | Permeability | Effects | Index Medicus | vascular leakage | vasculotide | Tie-2 | angiopoietins | TEK | endothelial permeability | acute lung injury | sepsis | endotoxin
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8. Full Text Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
by Qin, Ying and Wolburg-Buchholz, Karen and Wolburg, Hartwig and Fujiwara, Yuko and Gridley, Thomas and Gendron-Maguire, Maureen and Tozawa, Yuzuru and Deutsch, Urban and Sato, Thomas N and Risau, Werner
Nature (London), ISSN 0028-0836, 07/1995, Volume 376, Issue 6535, pp. 70 - 74
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Organogenesis. Physiological fonctions | Organogenesis. Fetal development | Embryology: invertebrates and vertebrates. Teratology | Endothelium, Vascular - cytology | Cell Line | Blood Vessels - growth & development | Edema - embryology | Receptor, TIE-2 | Receptor, TIE-1 | Mice, Inbred C57BL | Receptor Protein-Tyrosine Kinases - physiology | Molecular Sequence Data | Receptors, TIE | DNA Primers | Blood Vessels - embryology | Cell Division - physiology | Phenotype | Animals | Mutagenesis | Receptor Protein-Tyrosine Kinases - genetics | Base Sequence | Hemorrhage - embryology | Mice | Cell Differentiation - physiology | Endothelium, Vascular - embryology | Tyrosine | Vascular endothelium | Embryology, Experimental | Research | Neovascularization | Vascular resistance | Genetics | Mutation | Circulatory system | Rodents | Index Medicus
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9. Full Text Tie-2 regulates the stemness and metastatic properties of prostate cancer cells
by Tang, Kai-Dun and Holzapfel, Boris M and Liu, Ji and Lee, Terence Kin-Wah and Ma, Stephanie and Jovanovic, Lidija and An, Jiyuan and Russell, Pamela J and Clements, Judith A and Hutmacher, Dietmar W and Ling, Ming-Tat
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 3, pp. 2572 - 2584
Metastasis | Cancer stem cells | Tie-2 | Prostate cancer | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Prostatic Neoplasms - metabolism | RNA, Small Interfering - genetics | Cell Proliferation | Stromal Cells - pathology | Humans | Male | Immunoenzyme Techniques | Prostatic Neoplasms - genetics | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Receptor, TIE-2 - metabolism | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Receptor, TIE-2 - antagonists & inhibitors | RNA, Messenger - genetics | Stromal Cells - metabolism | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion | Receptor, TIE-2 - genetics | Xenograft Model Antitumor Assays | Osteoblasts - pathology | Prostatic Neoplasms - secondary | Animals | Endothelium, Vascular - metabolism | Endothelium, Vascular - pathology | Mice, Inbred NOD | Mice | Osteoblasts - metabolism | Apoptosis | Index Medicus
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10. Full Text Expression of Ang-2/Tie-2 and PI3K/AKT in colorectal cancer
by Zhang, Ji-Hong and Wang, Li-Hua and Li, Xiang-Jun and Wang, Ai-Ping and Reng, Li-Qun and Xia, Feng-Guo and Yang, Zhi-Ping and Jiang, Jing and Wang, Xiao-Dan and Wen, Chun-Yang
Asian Pacific journal of cancer prevention : APJCP, ISSN 1513-7368, 2014, Volume 15, Issue 20, pp. 8651 - 8656
Angiogenin-2 | AKT | PI3K | Tie-2 | Colorectal cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Colorectal Neoplasms - surgery | Predictive Value of Tests | Adenocarcinoma - pathology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Real-Time Polymerase Chain Reaction - methods | RNA, Messenger - analysis | Male | Case-Control Studies | Oncogene Protein v-akt - genetics | Adult | Female | Adenocarcinoma - genetics | Up-Regulation - genetics | Tissue Embedding | Blotting, Western | Disease Progression | Receptor, TIE-2 - genetics | Phosphatidylinositol 3-Kinases - genetics | Aged | Colorectal Neoplasms - pathology | Adenocarcinoma - surgery
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11. Full Text TIE-2 and VEGFR kinase activities drive immunosuppressive function of TIE-2-expressing monocytes in human breast tumors
by Ibberson, Mark and Bron, Sylvian and Guex, Nicolas and Hull, Eveline Faes-Van't and Ifticene-Treboux, Assia and Henry, Luc and Lehr, Hans-Anton and Delaloye, Jean-François and Coukos, George and Xenarios, Ioannis and Doucey, Marie-Agnès
Clinical cancer research, ISSN 1078-0432, 07/2013, Volume 19, Issue 13, pp. 3439 - 3449
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Breast Neoplasms - immunology | Dendritic Cells - immunology | Humans | Monocytes - metabolism | Gene Expression Profiling | Monocytes - immunology | Breast Neoplasms - metabolism | T-Lymphocytes, Regulatory - immunology | CD11c Antigen - metabolism | Lymphocyte Activation - immunology | Receptors, Vascular Endothelial Growth Factor - metabolism | Female | Receptor, TIE-2 - metabolism | Dendritic Cells - metabolism | Antigen-Presenting Cells - metabolism | Angiogenesis Inhibitors - pharmacology | Immunophenotyping | Antigen-Presenting Cells - immunology | Monocytes - drug effects | B7-2 Antigen - metabolism | Phenotype | Breast Neoplasms - genetics | Breast Neoplasms - pathology | T-Lymphocyte Subsets - metabolism | Neovascularization, Pathologic - metabolism | Cluster Analysis | Index Medicus
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