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Journal Article
The Journal of neuroscience, ISSN 1529-2401, 08/2016, Volume 36, Issue 31, pp. 8149 - 8159
Journal Article
Cancer discovery, ISSN 2159-8290, 04/2017, Volume 7, Issue 4, pp. 400 - 409
Entrectinib, a potent oral inhibitor of the tyrosine kinases TRKA/B/C, ROS1, and ALK, was evaluated in two phase I studies in patients with advanced or... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Benzamides - pharmacokinetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Receptor, trkA - antagonists & inhibitors | Male | Receptor, trkB - genetics | Indazoles - administration & dosage | Protein Kinase Inhibitors - adverse effects | Mammary Analogue Secretory Carcinoma - genetics | Dose-Response Relationship, Drug | Benzamides - administration & dosage | Membrane Glycoproteins - antagonists & inhibitors | Receptor, trkC - genetics | Anaplastic Lymphoma Kinase | Melanoma - genetics | Colorectal Neoplasms - drug therapy | Receptor, trkB - antagonists & inhibitors | Aged, 80 and over | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Benzamides - adverse effects | Carcinoma, Non-Small-Cell Lung - pathology | Crizotinib | Protein Kinase Inhibitors - pharmacokinetics | Proto-Oncogene Proteins - antagonists & inhibitors | Pyridines - administration & dosage | Carcinoma, Non-Small-Cell Lung - genetics | Receptor, trkC - antagonists & inhibitors | Melanoma - pathology | Mammary Analogue Secretory Carcinoma - drug therapy | Membrane Glycoproteins - genetics | Protein Kinase Inhibitors - administration & dosage | Sequestosome-1 Protein - genetics | Pyrazoles - administration & dosage | Indazoles - pharmacokinetics | Receptor Protein-Tyrosine Kinases - genetics | Oncogene Proteins, Fusion - genetics | Melanoma - drug therapy | Adolescent | Receptor, trkA - genetics | Oncogene Proteins, Fusion - antagonists & inhibitors | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Indazoles - adverse effects | Colorectal Neoplasms - pathology | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus
Journal Article
Nature neuroscience, ISSN 1097-6256, 11/2012, Volume 15, Issue 11, pp. 1506 - 1515
The neurotrophin brain-derived neurotrophic factor (BDNF) and its receptor TrkB participate in diverse neuronal functions, including activity-dependent synaptic plasticity that is crucial for learning and memory... 
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Disks Large Homolog 4 Protein | Humans | Dendritic Spines - metabolism | Green Fluorescent Proteins - genetics | Receptor, trkB - genetics | Brain-Derived Neurotrophic Factor - pharmacology | Phosphorylation - genetics | Neurons - ultrastructure | Long-Term Potentiation - drug effects | Time Factors | Guanine Nucleotide Exchange Factors - metabolism | Long-Term Potentiation - physiology | Excitatory Postsynaptic Potentials - genetics | Synaptophysin - metabolism | Glutamic Acid - pharmacology | Immunoprecipitation - methods | Maze Learning - physiology | Silver Staining | Rats | Spatial Behavior - physiology | Mice, Transgenic | Excitatory Amino Acid Antagonists - pharmacology | Mutation - genetics | Serine - metabolism | Cyclin-Dependent Kinase 5 - metabolism | Analysis of Variance | Guanylate Kinases - metabolism | Mice | Memory - physiology | Excitatory Postsynaptic Potentials - drug effects | Ribosomal Protein S6 Kinases | Quinoxalines - pharmacology | Transfection | Dendritic Spines - drug effects | Neurons - physiology | Membrane Proteins - metabolism | Neurons - drug effects | T-Lymphoma Invasion and Metastasis-inducing Protein 1 | Brain - cytology | Cyclin-Dependent Kinase 5 - deficiency | Mice, Inbred C57BL | Cells, Cultured | Long-Term Potentiation - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | In Vitro Techniques | Receptor, trkB - metabolism | rac1 GTP-Binding Protein - metabolism | Psychological aspects | Neuroplasticity | Learning | Phosphorylation | Brain-derived neurotrophic factor | Memory | Physiological aspects | Research | Growth factor receptors | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e70616 - e70616
Mechanisms governing the metastasis of endometrial carcinoma (EC) are poorly defined. Recent data support a role for the cell surface receptor tyrosine kinase TrkB in the progression of several human tumors... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Proliferation | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Receptor, trkB - genetics | Epithelial-Mesenchymal Transition - genetics | Cell Movement - genetics | Brain-Derived Neurotrophic Factor - pharmacology | Neoplasm Grading | Endometrial Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Receptor, trkB - antagonists & inhibitors | Adult | Female | Tumor Cells, Cultured | Anoikis - genetics | Tumor Burden | Enzyme Activation - drug effects | Cell Transformation, Neoplastic - metabolism | Animals | Cell Line, Tumor | Endometrial Neoplasms - pathology | Aged | Mice | Neoplasm Staging | Twist-Related Protein 1 - metabolism | Receptor, trkB - metabolism | Carcinoma | B cells | Metastasis | Analysis | Stem cells | Cancer | Cell culture | Brain | Transformation | Mesenchyme | Lung cancer | Childrens health | Kinases | Cancer therapies | Cell surface | Lymph nodes | Metastases | Signal transduction | Suspension culture | Cell growth | Surgery | Protein-tyrosine kinase receptors | Protein-tyrosine kinase | Endometrium | Tyrosine | Invasiveness | RNA-mediated interference | Gynecology | Radiation therapy | Tumor cell lines | Gene expression | Ribonucleic acid--RNA | Obstetrics | Medicine | Chemotherapy | Hospitals | Brain-derived neurotrophic factor | Depletion | Overexpression | Medical prognosis | Anoikis | TrkB receptors | Laboratory animals | Cell migration | Tumors | Peritoneum | Index Medicus | RNA | Ribonucleic acid
Journal Article
Psychopharmacology, ISSN 0033-3158, 2/2016, Volume 233, Issue 3, pp. 405 - 415
Journal Article