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Journal Article
JNEN: Journal of Neuropathology & Experimental Neurology, ISSN 0022-3069, 05/2004, Volume 63, Issue 5, pp. 441 - 449
Several molecular and histopathological prognostic markers have been proposed for the therapeutic stratification of medulloblastoma patients. Amplification of... 
TrkC | N-myc | Prognosis | c-myc | Anaplasia | Medulloblastoma | medulloblastoma | BEHAVIOR | IN-SITU HYBRIDIZATION | PATHOLOGY | LARGE CELL/ANAPLASTIC MEDULLOBLASTOMAS | BETA-CATENIN | prognosis | VARIANT | NEUROSCIENCES | CLINICAL NEUROLOGY | anaplasia | ONCOGENE AMPLIFICATION | NEUROTROPHIN RECEPTOR TRKC | GENE-EXPRESSION | PEDIATRIC-ONCOLOGY-GROUP | n-myc | COMPARATIVE GENOMIC HYBRIDIZATION | Predictive Value of Tests | Anaplasia - genetics | Cytoskeletal Proteins - genetics | Humans | Child, Preschool | Infant | Male | Wnt Proteins | RNA, Messenger - metabolism | DNA-Binding Proteins - metabolism | Receptor, trkC - genetics | Medulloblastoma - pathology | Anaplasia - pathology | Trans-Activators - genetics | Adult | Cytoskeletal Proteins - metabolism | Female | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Active Transport, Cell Nucleus - genetics | Child | Cerebellar Neoplasms - metabolism | Gene Expression Regulation, Neoplastic - genetics | Basic Helix-Loop-Helix Transcription Factors | Proto-Oncogene Proteins - metabolism | beta Catenin | Zebrafish Proteins | Proto-Oncogene Proteins - genetics | Survival Rate | Up-Regulation - genetics | Medulloblastoma - metabolism | Cerebellar Neoplasms - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Transcription Factors - metabolism | Adolescent | Trans-Activators - metabolism | Biomarkers, Tumor - genetics | Proto-Oncogene Proteins c-myc - genetics | Tumor Suppressor Proteins
Journal Article
Cancer Discovery, ISSN 2159-8274, 04/2017, Volume 7, Issue 4, pp. 400 - 409
Entrectinib, a potent oral inhibitor of the tyrosine kinases TRKA/B/C, ROS1, and ALK, was evaluated in two phase I studies in patients with advanced or... 
REARRANGEMENT | ONCOGENE | ONCOLOGY | ANALOG SECRETORY CARCINOMA | LANDSCAPE | KINASE FUSIONS | SARCOMAS | ETV6-NTRK3 GENE FUSION | CRIZOTINIB | GENOMIC ALTERATIONS | CLINICAL-RESPONSE | Benzamides - pharmacokinetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Receptor, trkA - antagonists & inhibitors | Male | Receptor, trkB - genetics | Indazoles - administration & dosage | Protein Kinase Inhibitors - adverse effects | Mammary Analogue Secretory Carcinoma - genetics | Dose-Response Relationship, Drug | Benzamides - administration & dosage | Membrane Glycoproteins - antagonists & inhibitors | Receptor, trkC - genetics | Anaplastic Lymphoma Kinase | Melanoma - genetics | Colorectal Neoplasms - drug therapy | Receptor, trkB - antagonists & inhibitors | Aged, 80 and over | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Benzamides - adverse effects | Carcinoma, Non-Small-Cell Lung - pathology | Crizotinib | Protein Kinase Inhibitors - pharmacokinetics | Proto-Oncogene Proteins - antagonists & inhibitors | Pyridines - administration & dosage | Carcinoma, Non-Small-Cell Lung - genetics | Receptor, trkC - antagonists & inhibitors | Melanoma - pathology | Mammary Analogue Secretory Carcinoma - drug therapy | Membrane Glycoproteins - genetics | Protein Kinase Inhibitors - administration & dosage | Sequestosome-1 Protein - genetics | Pyrazoles - administration & dosage | Indazoles - pharmacokinetics | Receptor Protein-Tyrosine Kinases - genetics | Oncogene Proteins, Fusion - genetics | Melanoma - drug therapy | Adolescent | Receptor, trkA - genetics | Oncogene Proteins, Fusion - antagonists & inhibitors | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Indazoles - adverse effects | Colorectal Neoplasms - pathology | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 5, pp. 444 - 450
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2015, Volume 5, Issue 1, p. 9133
This study attempted to graft neurotrophin-3 (NT-3) receptor (TrkC) gene modified mesenchymal stem cells (TrkC-MSCs) into the demyelinated spinal cord and to... 
MYELIN OLIGODENDROCYTE GLYCOPROTEIN | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MULTIPLE-SCLEROSIS | CNS REMYELINATION | POTASSIUM CHANNELS | MULTIDISCIPLINARY SCIENCES | NEUROTROPHIN EXPRESSION | AXONAL CONDUCTION | ANIMAL-MODELS | CENTRAL-NERVOUS-SYSTEM | MARROW STROMAL CELLS | Oligodendroglia - metabolism | Demyelinating Diseases - genetics | Demyelinating Diseases - therapy | Neurotrophin 3 - genetics | Demyelinating Diseases - metabolism | Recovery of Function | Myelin Sheath - metabolism | Evoked Potentials, Motor | Mesenchymal Stromal Cells - cytology | Receptor, trkC - genetics | Spinal Cord Diseases - metabolism | Spinal Cord Diseases - therapy | Adenoviridae - genetics | Cell Differentiation | Oligodendroglia - cytology | Transgenes | Disease Models, Animal | Gene Expression | Transduction, Genetic | Electroacupuncture | Mesenchymal Stromal Cells - metabolism | Rats | Genetic Vectors - genetics | Spinal Cord Diseases - genetics | Animals | Neurotrophin 3 - metabolism | Mesenchymal Stem Cell Transplantation | Receptor, trkC - metabolism | Spinal cord | Mesenchyme | Myelin | Secretion | Cortex | Recovery of function | Stem cell transplantation | Motor evoked potentials | Neurotrophin 3 | Motor task performance | Glial stem cells | Myelin basic protein | Myelination | Ethidium bromide | Allografts | Evoked potentials | Rodents | Oligodendrocytes | Stem cells | Immunoelectron microscopy | Potassium channels (voltage-gated) | Acupuncture | Immunofluorescence
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 05/2017, Volume 173, pp. 58 - 66
Journal Article
Journal Article