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Cell Host & Microbe, ISSN 1931-3128, 05/2014, Volume 15, Issue 5, pp. 623 - 635
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 01/2015, Volume 48, Issue 1, pp. 76 - 85
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2007, Volume 178, Issue 4, pp. 2380 - 2386
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e42386
Understanding the mechanisms by which pathogens induce vascular inflammation and dysfunction may reveal novel therapeutic targets in sepsis and related... 
NUCLEOTIDE OLIGOMERIZATION DOMAIN | KAPPA-B ACTIVATION | SMOOTH-MUSCLE | NITRIC-OXIDE SYNTHASE | TOLL-LIKE RECEPTOR | BIOLOGY | SEPTIC SHOCK | ORGAN-CULTURE | INDUCTION | PATTERN-RECOGNITION RECEPTORS | SEVERE SEPSIS | Peptidoglycan - metabolism | Vasculitis - metabolism | Humans | Nod1 Signaling Adaptor Protein - agonists | Vasculitis - pathology | NF-kappa B - immunology | Muscle, Smooth, Vascular - immunology | Male | NF-kappa B - metabolism | Receptor-Interacting Protein Serine-Threonine Kinase 2 - immunology | Gram-Negative Bacteria - metabolism | Peptidoglycan - immunology | Gram-Negative Bacteria - immunology | MAP Kinase Signaling System - immunology | Nod1 Signaling Adaptor Protein - metabolism | Receptor-Interacting Protein Serine-Threonine Kinase 2 - metabolism | Vasculitis - immunology | p38 Mitogen-Activated Protein Kinases - metabolism | Endothelium, Vascular - immunology | Vasculitis - therapy | Endothelial Cells - metabolism | Cells, Cultured | Rats | MAP Kinase Kinase Kinases - metabolism | Toll-Like Receptor 4 - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Nod1 Signaling Adaptor Protein - immunology | Rats, Sprague-Dawley | Toll-Like Receptor 4 - metabolism | MAP Kinase Kinase Kinases - immunology | Endothelial Cells - immunology | Muscle, Smooth, Vascular - pathology | Animals | Endothelium, Vascular - pathology | Endothelial Cells - pathology | Infection | Septic shock | Inflammation | Health aspects | Endothelium | Heart | Cell culture | Gram-positive bacteria | Smooth muscle | Inflammatory response | Stimulation | Activation | Blood | Signal transduction | Pathways | Rodents | Toll-like receptors | Nod1 protein | TAK1 protein | Pulmonary arteries | Therapeutic applications | Cell walls | Feature recognition | Peptidoglycans | Muscles | Blood vessels | MAP kinase | Pharmacology | Pattern recognition | TLR4 protein | Endothelial cells | Signaling | Organ culture | Sepsis | Ligands | In vivo methods and tests | Adapter proteins
Journal Article
Infection and Immunity, ISSN 0019-9567, 03/2014, Volume 82, Issue 3, pp. 1112 - 1122
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e73103
In recent years, genome wide association studies have discovered a large number of gene loci that play a functional role in innate and adaptive immune pathways... 
LOCI | CROHNS-DISEASE | MULTIDISCIPLINARY SCIENCES | GENES | LEPROSY | Genetic Predisposition to Disease | Mycobacterium leprae | Humans | Polymorphism, Genetic - immunology | Protein-Serine-Threonine Kinases - genetics | India - epidemiology | Nod2 Signaling Adaptor Protein - immunology | Male | Nod2 Signaling Adaptor Protein - genetics | Leprosy - immunology | Receptor-Interacting Protein Serine-Threonine Kinase 2 - immunology | Signal Transduction - genetics | Receptor-Interacting Protein Serine-Threonine Kinase 2 - genetics | Th1 Cells - immunology | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Haplotypes - genetics | Signal Transduction - immunology | Alleles | Female | Polymorphism, Genetic - genetics | Protein-Serine-Threonine Kinases - immunology | Haplotypes - immunology | Leprosy - epidemiology | Leprosy - genetics | Medical research | Genes | Genomics | Leprosy | Medicine, Experimental | Genetic aspects | Genomes | Research | Haplotypes | Disease | Zoology | Intracellular signalling | Infections | Lymphocytes T | Kinases | Adaptive control | Tropical diseases | Ethics | Signal transduction | Immunology | Pathways | Bacteria | Life sciences | LRRK2 protein | Chromosomes | Genotypes | Public health | NOD2 protein | Cytokines | Gene expression | Patients | Loci | Tuberculosis | Genotyping | Intracellular | Molecular biology
Journal Article
Molecular Immunology, ISSN 0161-5890, 04/2015, Volume 64, Issue 2, pp. 235 - 243
Innate immunity is considered to be critical in the pathogenesis of fungal keratitis. Pattern recognition receptors (PRRs) recognize conserved microbial... 
NOD2 | Aspergillus fumigatus | HCECs | TLR2 | ACTIVATION | TOLERANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CORNEAL EPITHELIAL-CELLS | INNATE | MICROBIAL KERATITIS | IMMUNOLOGY | FUNGAL KERATITIS | PATHOGEN RECOGNITION | RESPONSES | PATTERN-RECOGNITION | RECEPTORS | Interleukin-8 - genetics | RNA, Small Interfering - genetics | Epithelial Cells - metabolism | Toll-Like Receptor 2 - agonists | Toll-Like Receptor 2 - antagonists & inhibitors | Toll-Like Receptor 2 - genetics | I-kappa B Proteins - immunology | Humans | Tumor Necrosis Factor-alpha - genetics | Cornea - immunology | Nod2 Signaling Adaptor Protein - genetics | Receptor-Interacting Protein Serine-Threonine Kinase 2 - immunology | Receptor-Interacting Protein Serine-Threonine Kinase 2 - genetics | I-kappa B Proteins - genetics | Transcription Factor RelA - genetics | Zymosan - pharmacology | Tumor Necrosis Factor-alpha - immunology | Transcription Factor RelA - immunology | Nod2 Signaling Adaptor Protein - agonists | Spores, Fungal - immunology | Cornea - microbiology | NF-KappaB Inhibitor alpha | Receptor Cross-Talk | Interleukin-6 - genetics | Signal Transduction | Gene Expression Regulation | Nod2 Signaling Adaptor Protein - immunology | Acetylmuramyl-Alanyl-Isoglutamine - pharmacology | Host-Pathogen Interactions | Cornea - metabolism | Aspergillus fumigatus - immunology | Epithelial Cells - immunology | Epithelial Cells - microbiology | Interleukin-6 - immunology | Nod2 Signaling Adaptor Protein - antagonists & inhibitors | Toll-Like Receptor 2 - immunology | Interleukin-8 - immunology | Cell Line, Transformed | RNA, Small Interfering - metabolism | Oligomers | Keratitis | Ophthalmology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2012, Volume 287, Issue 35, pp. 29213 - 29226
Journal Article
Inflammatory Bowel Diseases, ISSN 1078-0998, 04/2012, Volume 18, Issue 4, pp. 603 - 612
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 06/2015, Volume 36, Issue 2, pp. 457 - 473
Journal Article
蛋白质与细胞:英文版, ISSN 1674-800X, 2017, Volume 8, Issue 1, pp. 55 - 66
The innate immune system is critical for clearing infection, and is tightly regulated to avert excessive tissue damage. Nod1/2-Rip2 signaling, which is... 
细菌感染 | 胞壁酰二肽 | 化促 | 炎症 | 介导 | 炎性细胞因子 | 内质网应激 | 磷酸化 | Life Sciences | Biochemistry, general | Protein Science | Stem Cells | Human Genetics | LRRK2 | NF-κB activation | Nod2 | Inflammation | Developmental Biology | Cell Biology | Rip2 | INNATE | CELL BIOLOGY | REGULATOR | NF-kappa B activation | REPEAT KINASE 2 | DISEASE | PARKINSONS | MUTATIONS | STRESS | ASSOCIATION | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - immunology | Humans | Immunity, Innate - genetics | Nod2 Signaling Adaptor Protein - immunology | Nod2 Signaling Adaptor Protein - genetics | Inflammation - immunology | Receptor-Interacting Protein Serine-Threonine Kinase 2 - immunology | Signal Transduction - genetics | Nod1 Signaling Adaptor Protein - immunology | Receptor-Interacting Protein Serine-Threonine Kinase 2 - genetics | Mice, Knockout | Signal Transduction - immunology | Phosphorylation - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | HEK293 Cells | Inflammation - genetics | Mice | Phosphorylation - immunology | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Cytokines - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - genetics | Cytokines - immunology | Nod1 Signaling Adaptor Protein - genetics | Cytokines | Leprosy | Bacterial infections
Journal Article
Human Immunology, ISSN 0198-8859, 2012, Volume 73, Issue 6, pp. 668 - 672
Journal Article
Journal of Reproductive Immunology, ISSN 0165-0378, 2009, Volume 80, Issue 1, pp. 33 - 40
Journal Article