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disease models, animal (42) 42
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apoptosis - physiology (40) 40
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Cell Death and Differentiation, ISSN 1350-9047, 09/2016, Volume 23, Issue 9, pp. 1565 - 1576
Necroptosis is a caspase-independent form of cell death that is triggered by activation of the receptor interacting serine/threonine kinase 3 (RIPK3) and... 
MYOCARDIAL-INFARCTION | RECEPTOR-INTERACTING PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOMAIN-LIKE PROTEIN | REPERFUSION INJURY | MIXED LINEAGE KINASE | PROGRAMMED NECROSIS | MEDIATES NECROPTOSIS | TNF-ALPHA | NECROPTOTIC CELL-DEATH | NF-KAPPA-B | CELL BIOLOGY | Protein Kinases - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Inflammation - pathology | Protein Kinases - genetics | Sepsis - etiology | Apoptosis - drug effects | Colitis - pathology | Male | Inflammation - metabolism | Sepsis - pathology | Sepsis - metabolism | Colitis - chemically induced | Female | Protein Kinases - deficiency | Reperfusion Injury - metabolism | Disease Models, Animal | Systemic Inflammatory Response Syndrome - metabolism | Lipopolysaccharides - toxicity | Reperfusion Injury - pathology | Mice, Inbred C57BL | Ceruletide - toxicity | Reperfusion Injury - mortality | Pancreatitis - chemically induced | Dextran Sulfate - toxicity | Mice, Knockout | Tumor Necrosis Factor alpha-Induced Protein 3 - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Systemic Inflammatory Response Syndrome - pathology | Animals | Colitis - metabolism | Pancreatitis - pathology | Systemic Inflammatory Response Syndrome - etiology | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Pancreatitis - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - antagonists & inhibitors | Tumor Necrosis Factor alpha-Induced Protein 3 - deficiency | Index Medicus | Original Paper
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7516, pp. 90 - 94
Necroptosis has emerged as an important pathway of programmed cell death in embryonic development, tissue homeostasis, immunity and inflammation(1-8). RIPK1 is... 
CHRONIC INTESTINAL INFLAMMATION | CELLS | KAPPA-B ACTIVATION | NECROSIS-FACTOR RECEPTOR | MULTIDISCIPLINARY SCIENCES | IN-VIVO | KINASE | ALPHA-DEPENDENT APOPTOSIS | MICE | SKIN INFLAMMATION | DELETION | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Inflammation - pathology | Skin - cytology | Epithelial Cells - metabolism | Skin - metabolism | Caspase 8 - metabolism | Homeostasis | Paneth Cells - pathology | Male | Intestines - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | Necrosis | Receptors, Tumor Necrosis Factor, Type I - deficiency | Inflammation - metabolism | Female | Epithelial Cells - cytology | Skin - pathology | Paneth Cells - metabolism | Intestines - pathology | Cell Survival | Fas-Associated Death Domain Protein - metabolism | Fas-Associated Death Domain Protein - deficiency | Epithelial Cells - pathology | Mice, Knockout | Keratinocytes - pathology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Keratinocytes - metabolism | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Myeloid Differentiation Factor 88 - metabolism | Apoptosis | Intestines - cytology | Physiological aspects | Physiological research | Inflammation | Research | Protein kinases | Pathology | Antibiotics | Rodents | Skin | Kinases | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7516, pp. 95 - 99
Receptor interacting protein kinase 1 (RIPK1) has an essential role in the signalling triggered by death receptors and pattern recognition receptors(1,2).... 
UBIQUITINATION | NECROPTOSIS | MEDIATED RECOMBINATION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | KINASE | MICE | TNF-ALPHA | CRE-LOXP | NECROSIS-FACTOR RECEPTOR-1 | CELL-DEATH | Intestines - drug effects | Protein Kinases - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Inflammation - pathology | Epithelial Cells - metabolism | Apoptosis - drug effects | Epithelial Cells - drug effects | Caspase 8 - metabolism | Male | NF-kappa B - metabolism | Intestines - metabolism | Organoids - enzymology | Necrosis | Caspase 8 - genetics | Receptors, Tumor Necrosis Factor, Type I - deficiency | Inflammation - metabolism | Gene Deletion | Organoids - metabolism | Female | Homeostasis - drug effects | Epithelial Cells - cytology | Tumor Necrosis Factors - pharmacology | Cell Survival - drug effects | Epithelium - drug effects | Epithelium - pathology | Intestines - pathology | Epithelium - metabolism | Organoids - cytology | Epithelial Cells - pathology | Mice, Knockout | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Myeloid Differentiation Factor 88 - deficiency | Organoids - drug effects | Survival Analysis | Anti-Bacterial Agents - pharmacology | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Intestines - cytology | Protein research | Physiological aspects | Homeostasis | Research | Epithelium | Protein kinases | Apoptosis | Proteins | Genotype & phenotype | Antibiotics | Transgenic animals | Rodents | Ligands | Colon | Kinases | Index Medicus
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2013, Volume 23, Issue 8, pp. 994 - 1006
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7338, pp. 368 - 373
Journal Article
Nature, ISSN 0028-0836, 12/2016, Volume 540, Issue 7631, pp. 129 - 133
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2013, Volume 123, Issue 2, pp. 700 - 711
Journal Article
Hepatology, ISSN 0270-9139, 05/2013, Volume 57, Issue 5, pp. 1773 - 1783
Journal Article
Immunity, ISSN 1074-7613, 2011, Volume 35, Issue 6, pp. 908 - 918
Journal Article