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Nature, ISSN 0028-0836, 2013, Volume 503, Issue 7477, pp. 493 - 499
Adiponectin secreted from adipocytes binds to adiponectin receptors AdipoR1 and AdipoR2, and exerts antidiabetic effects via activation of AMPK and PPAR-alpha... 
CRUCIAL ROLE | SKELETAL-MUSCLE | ACTIVATED PROTEIN-KINASE | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | MECHANISMS | ADIPONECTIN LEVELS | EXPRESSION | Liver - pathology | Obesity - drug therapy | Longevity - drug effects | Adipose Tissue, White - metabolism | Receptors, Adiponectin - metabolism | Diabetes Mellitus, Type 2 - metabolism | Muscle Fibers, Skeletal - drug effects | Obesity - genetics | Glucose Intolerance - drug therapy | Liver - drug effects | Piperidines - pharmacology | Inflammation - drug therapy | Adenylate Kinase - metabolism | Diet, High-Fat | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Receptors, Adiponectin - agonists | Adiponectin - metabolism | Drug Evaluation, Preclinical | Diabetes Mellitus, Type 2 - complications | Adipose Tissue, White - pathology | Adiponectin - pharmacology | Dyslipidemias - drug therapy | Piperidines - administration & dosage | Administration, Oral | Obesity - complications | Piperidines - metabolism | Liver - metabolism | Diabetes Mellitus, Type 2 - prevention & control | Insulin Resistance | Obesity - physiopathology | Transcription Factors - biosynthesis | Mitochondria - metabolism | Mitochondria - drug effects | Enzyme Activation - drug effects | Triglycerides - metabolism | Small Molecule Libraries - chemistry | Receptors, Adiponectin - deficiency | Animals | Signal Transduction - drug effects | Piperidines - therapeutic use | Muscle Fibers, Skeletal - cytology | Mice | Oxidative Stress - drug effects | PPAR alpha - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Adipose Tissue, White - drug effects | Receptors, Adiponectin - genetics | Muscles - cytology | Obesity | Insulin resistance | Muscular system | Kinases | Rodents
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 44, pp. 15810 - 15815
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0199256
Journal Article
BMC Biotechnology, ISSN 1472-6750, 2011, Volume 11, Issue 1, pp. 90 - 90
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 01/2017, Volume 439, Issue C, pp. 273 - 285
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2007, Volume 569, Issue 1, pp. 155 - 162
Recently, the insulin-sensitizing adipokine adiponectin and the insulin resistance-inducing adipokine tumor necrosis factor-α (TNF-α) were reported to inhibit... 
Adipose tissue | β-adrenoceptor | Insulin resistance | Tumor necrosis factor-α | Catecholamine | Adiponectin receptor | 3T3-L1 adipocyte | Adiponectin | 3T3-L1 ADIPOCYTES | adiponectin | METABOLIC SYNDROME | ACTIVATED PROTEIN-KINASE | SYMPATHETIC-NERVOUS-SYSTEM | adipose tissue | ACETYL-COA CARBOXYLASE | beta-adrenoceptor | INDUCED INSULIN-RESISTANCE | tumor necrosis factor-alpha | SKELETAL-MUSCLE | catecholamine | FATTY-ACID OXIDATION | ADRENERGIC STIMULATION | adiponectin receptor | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | insulin resistance | Tumor Necrosis Factor-alpha - metabolism | Ethanolamines - pharmacology | Tumor Necrosis Factor-alpha - genetics | Multienzyme Complexes - metabolism | Adipocytes - cytology | Male | Adipocytes - drug effects | RNA, Messenger - metabolism | AMP-Activated Protein Kinases | Receptors, Adiponectin | Isoquinolines - pharmacology | Adiponectin - genetics | Adiponectin - metabolism | Protein-Serine-Threonine Kinases - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Fenoterol - pharmacology | Colforsin - pharmacology | Mice, Inbred C57BL | RNA, Messenger - genetics | Adrenergic beta-Agonists - pharmacology | Receptors, Cell Surface - metabolism | Adenylyl Cyclases - metabolism | 3T3-L1 Cells | Down-Regulation - drug effects | Enzyme Activation - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Sulfonamides - pharmacology | Blotting, Western | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Animals | Adipocytes - metabolism | Isoproterenol - pharmacology | Mice | Receptors, Cell Surface - genetics
Journal Article
Nature Reviews Endocrinology, ISSN 1759-5029, 01/2014, Volume 10, Issue 1, pp. 4 - 4
Journal Article
Pharmacological Research, ISSN 1043-6618, 05/2017, Volume 119, pp. 289 - 302
Journal Article