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Journal of Biological Chemistry, ISSN 0021-9258, 04/2011, Volume 286, Issue 15, pp. 13460 - 13469
The anti-inflammatory effects of globular adiponectin (gAcrp) are mediated by IL-10/heme oxygenase 1 (HO-1)-dependent pathways. Although full-length (flAcrp)... 
RAT KUPFFER CELLS | OXIDATIVE STRESS | TERM TREATMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALCOHOLIC LIVER-DISEASE | FATTY LIVER | INJURY | ETHANOL | TNF-ALPHA | ALTERNATIVE ACTIVATION | PROGRESSION | Heme Oxygenase-1 - metabolism | Central Nervous System Depressants - adverse effects | Male | Central Nervous System Depressants - pharmacology | Signal Transduction - immunology | Ethanol - adverse effects | Myeloid Differentiation Factor 88 - immunology | Adiponectin - metabolism | Kupffer Cells - metabolism | Membrane Proteins - metabolism | Heme Oxygenase (Decyclizing) - metabolism | Cytokines - immunology | Cell Line | Adiponectin - pharmacology | Cytokines - metabolism | Immunity, Innate - drug effects | Gene Expression Regulation - immunology | Rats | Membrane Proteins - immunology | Toll-Like Receptor 4 - immunology | STAT6 Transcription Factor - metabolism | STAT6 Transcription Factor - immunology | Rats, Sprague-Dawley | Toll-Like Receptor 4 - metabolism | Gene Expression Regulation - drug effects | Immunity, Innate - immunology | Ethanol - pharmacology | Animals | Signal Transduction - drug effects | Heme Oxygenase-1 - immunology | Lipopolysaccharides - pharmacology | Heme Oxygenase (Decyclizing) - immunology | Mice | Adiponectin - immunology | Myeloid Differentiation Factor 88 - metabolism | Kupffer Cells - immunology | Gene Regulation | Gene Expression | Liver Injury | Signal Transduction | Innate Immunity | Alcohol | AMP-activated Kinase (AMPK) | Interferon | mRNA | Chemokines | Macrophage
Journal Article
Journal of Molecular Cell Biology, ISSN 1674-2788, 04/2016, Volume 8, Issue 2, pp. 93 - 100
Adiponectin is an adipocyte-specific factor, first described in 1995. Over the past two decades, numerous studies have elucidated the physiological functions... 
metabolic syndrome | adiponectin | diabetes | obesity | Animals | Adiponectin - chemistry | Humans | Cells - metabolism | Models, Molecular | Receptors, Adiponectin - metabolism | Adiponectin - metabolism | Reviews
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 503, Issue 7477, pp. 493 - 499
Adiponectin secreted from adipocytes binds to adiponectin receptors AdipoR1 and AdipoR2, and exerts antidiabetic effects via activation of AMPK and PPAR-alpha... 
CRUCIAL ROLE | SKELETAL-MUSCLE | ACTIVATED PROTEIN-KINASE | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | MECHANISMS | ADIPONECTIN LEVELS | EXPRESSION | Liver - pathology | Obesity - drug therapy | Longevity - drug effects | Adipose Tissue, White - metabolism | Receptors, Adiponectin - metabolism | Diabetes Mellitus, Type 2 - metabolism | Muscle Fibers, Skeletal - drug effects | Obesity - genetics | Glucose Intolerance - drug therapy | Liver - drug effects | Piperidines - pharmacology | Inflammation - drug therapy | Adenylate Kinase - metabolism | Diet, High-Fat | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Receptors, Adiponectin - agonists | Adiponectin - metabolism | Drug Evaluation, Preclinical | Diabetes Mellitus, Type 2 - complications | Adipose Tissue, White - pathology | Adiponectin - pharmacology | Dyslipidemias - drug therapy | Piperidines - administration & dosage | Administration, Oral | Obesity - complications | Piperidines - metabolism | Liver - metabolism | Diabetes Mellitus, Type 2 - prevention & control | Insulin Resistance | Obesity - physiopathology | Transcription Factors - biosynthesis | Mitochondria - metabolism | Mitochondria - drug effects | Enzyme Activation - drug effects | Triglycerides - metabolism | Small Molecule Libraries - chemistry | Receptors, Adiponectin - deficiency | Animals | Signal Transduction - drug effects | Piperidines - therapeutic use | Muscle Fibers, Skeletal - cytology | Mice | Oxidative Stress - drug effects | PPAR alpha - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Adipose Tissue, White - drug effects | Receptors, Adiponectin - genetics | Muscles - cytology | Obesity | Insulin resistance | Muscular system | Kinases | Rodents
Journal Article
Journal Article