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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2018, Volume 26, Issue 13, pp. 3773 - 3784
Journal Article
Journal Article
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 06/2011, Volume 57, Issue 6, pp. 639 - 647
Effects of ranolazine alone and in the presence of phenylephrine (PE) or isoproterenol (ISO) on hemodynamics, coronary blood flow and heart rate (HR) in the... 
conscious dogs | ranolazine | antiadrenergic effect | coronary blood flow | hemodynamics | LATE SODIUM CURRENT | CARDIAC & CARDIOVASCULAR SYSTEMS | ANTIANGINAL AGENT | ISCHEMIA | RANDOMIZED CONTROLLED-TRIAL | ACUTE-CORONARY-SYNDROME | INHIBITION | ANGINA | THROMBOLYSIS | PHARMACOLOGY & PHARMACY | Acetanilides - metabolism | Piperazines - administration & dosage | Isoproterenol - toxicity | Adrenergic Antagonists - metabolism | Acetanilides - administration & dosage | Isoproterenol - administration & dosage | Hypertension - drug therapy | Piperazines - metabolism | Vasoconstrictor Agents - toxicity | Ganglionic Blockers - pharmacology | Phenylephrine - administration & dosage | Ranolazine | Dose-Response Relationship, Drug | Heart Rate - drug effects | Hexamethonium - pharmacology | Hypotension - drug therapy | Adrenergic Antagonists - therapeutic use | Hypertension - chemically induced | Acetanilides - therapeutic use | Piperazines - blood | Receptors, Adrenergic, beta - metabolism | Receptors, Adrenergic, alpha - metabolism | Receptors, Adrenergic, beta - chemistry | Vasoconstrictor Agents - administration & dosage | Guinea Pigs | Phenylephrine - toxicity | Adrenergic Antagonists - administration & dosage | Rats | Piperazines - therapeutic use | Receptors, Adrenergic, alpha - chemistry | Autonomic Agents - therapeutic use | Hypotension - chemically induced | Autonomic Agents - administration & dosage | Animals | Vasodilator Agents - toxicity | Adrenergic Antagonists - blood | Dogs | Acetanilides - blood | Hemodynamics - drug effects | Coronary Circulation - drug effects | Kinetics | Vasodilator Agents - administration & dosage
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2013, Volume 169, Issue 3, pp. 528 - 538
PDE3 and/or PDE4 control ventricular effects of catecholamines in several species but their relative effects in failing human ventricle are unknown. We... 
inotropism and lusitropism | human heart failure | and β | metoprolol | adrenoceptors | phosphodiesterases 3 and 4 | noradrenaline and adrenaline | Adrenergic beta-1 Receptor Antagonists - adverse effects | Heart Failure - surgery | Cyclic Nucleotide Phosphodiesterases, Type 3 - chemistry | Norepinephrine - pharmacology | Adrenergic alpha-Agonists - chemistry | Phosphodiesterase 3 Inhibitors - pharmacology | Humans | Middle Aged | Adrenergic beta-1 Receptor Antagonists - pharmacology | Heart Failure - physiopathology | Myocardial Contraction - drug effects | Receptors, Adrenergic, beta-1 - chemistry | Adrenergic beta-1 Receptor Antagonists - therapeutic use | Adrenergic beta-Agonists - chemistry | Epinephrine - agonists | Receptors, Adrenergic, beta-2 - chemistry | Cardiotonic Agents - therapeutic use | Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 4 - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 4 - chemistry | Adrenergic beta-2 Receptor Antagonists - pharmacology | Adrenergic beta-Agonists - pharmacology | Heart Transplantation | Metoprolol - therapeutic use | Receptors, Adrenergic, beta-1 - metabolism | Drug Resistance - drug effects | Heart Failure - metabolism | Anti-Arrhythmia Agents - therapeutic use | Cardiotonic Agents - pharmacology | Metoprolol - adverse effects | Norepinephrine - agonists | Phosphodiesterase 4 Inhibitors - pharmacology | Receptors, Adrenergic, beta-2 - metabolism | Heart Failure - drug therapy | Heart Ventricles - physiopathology | Anti-Arrhythmia Agents - adverse effects | Adrenergic alpha-Agonists - pharmacology | Heart Ventricles - metabolism | In Vitro Techniques | Epinephrine - pharmacology | Heart Ventricles - drug effects | Research Paper with | β1 and β2 adrenoceptors
Journal Article
Journal Article
Endocrinology, ISSN 0013-7227, 09/2013, Volume 154, Issue 9, pp. 3240 - 3250
The process involved in relocation of the coactivator, transducer of regulated cAMP-regulated element-binding protein (TORC) to the cytoplasm, unlike its... 
MEDIATED GENE-EXPRESSION | ACTIVATED PROTEIN-KINASE | SENSITIVE COINCIDENCE DETECTOR | SALT-INDUCIBLE KINASE | ENDOCRINOLOGY & METABOLISM | MELATONIN SYNTHESIS | CREB COACTIVATOR TORC2 | TRANSCRIPTIONAL COACTIVATOR | ARYLALKYLAMINE-N-ACETYLTRANSFERASE | CAMP | HORMONE TRANSCRIPTION | TOR Serine-Threonine Kinases - metabolism | Pineal Gland - metabolism | Adrenergic Agonists - pharmacology | Cytoplasm - metabolism | Male | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | Neuroendocrine Cells - cytology | Cell Nucleus - metabolism | Protein Processing, Post-Translational - drug effects | Isoenzymes - metabolism | Neuroendocrine Cells - metabolism | Biological Transport - drug effects | Phosphorylation - drug effects | Pineal Gland - cytology | Receptors, Adrenergic, beta - metabolism | Receptors, Adrenergic, alpha - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Receptors, Adrenergic, beta - chemistry | Protein Phosphatase 2 - antagonists & inhibitors | Nerve Tissue Proteins - agonists | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Receptors, Adrenergic, alpha - chemistry | Pineal Gland - drug effects | Rats, Sprague-Dawley | Adrenergic Antagonists - pharmacology | Nerve Tissue Proteins - metabolism | Animals | Norepinephrine - metabolism | Protein Phosphatase 2 - metabolism | Cell Nucleus - drug effects | Cytoplasm - drug effects | Neuroendocrine Cells - drug effects | Isoenzymes - antagonists & inhibitors
Journal Article
Journal Article
Cell Communication and Adhesion, ISSN 1541-9061, 08/2011, Volume 18, Issue 4, pp. 57 - 65
Journal Article
Journal Article
Journal Article
Molecular pharmacology, ISSN 0026-895X, 05/2016, Volume 89, Issue 5, pp. 541 - 551
N-methyl-d-aspartate receptors (NMDARs) are glutamate-gated ion channels that play key roles in brain physiology and pathology. Because numerous pathologic... 
Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Membrane Transport Modulators - chemistry | Expert Systems | Humans | Molecular Conformation | Imidazoles - chemistry | Receptors, N-Methyl-D-Aspartate - metabolism | Pyrimidines - metabolism | Piperidines - pharmacology | Oxadiazoles - pharmacology | Receptors, N-Methyl-D-Aspartate - chemistry | Binding Sites | Imidazoles - metabolism | Protein Subunits - genetics | Piperidines - metabolism | Computational Biology | Models, Molecular | Imidazoles - pharmacology | Pyrimidines - pharmacology | Recombinant Fusion Proteins - chemistry | Pyridazines - chemistry | Adrenergic alpha-Antagonists - metabolism | Ligands | Molecular Docking Simulation | Protein Subunits - antagonists & inhibitors | Mutation | Oxadiazoles - metabolism | Drugs, Investigational - pharmacology | Xenopus Proteins - genetics | Adrenergic alpha-Antagonists - pharmacology | Drugs, Investigational - metabolism | Pyridazines - pharmacology | Recombinant Fusion Proteins - metabolism | Protein Subunits - metabolism | Pyrimidines - chemistry | Receptors, N-Methyl-D-Aspartate - genetics | Xenopus Proteins - chemistry | Drugs, Investigational - chemistry | Membrane Transport Modulators - pharmacology | Pyridazines - metabolism | Protein Interaction Domains and Motifs | Oxadiazoles - chemistry | Allosteric Regulation - drug effects | Piperidines - chemistry | Adrenergic alpha-Antagonists - chemistry | Xenopus Proteins - antagonists & inhibitors | Membrane Transport Modulators - metabolism | Animals | Xenopus Proteins - metabolism | Protein Subunits - chemistry | Amino Acid Substitution | Index Medicus
Journal Article