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NATURE, ISSN 0028-0836, 01/2011, Volume 469, Issue 7329, pp. 241 - 244
beta-adrenergic receptors (beta ARs) are G-protein-coupled receptors (GPCRs) that activate intracellular G proteins upon binding catecholamine agonist ligands... 
CRYSTALLIZATION | AMINO-ACID | ACTIVATION | LIGAND-BINDING | BETA-ADRENERGIC-RECEPTORS | PROTEIN-COUPLED RECEPTOR | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | CRYSTALLOGRAPHY | HIGH-AFFINITY BINDING | BETA-ADRENERGIC RECEPTOR | Dobutamine - metabolism | Hydroxyquinolines - chemistry | Catecholamines - metabolism | Albuterol - pharmacology | Amphetamines - pharmacology | Adrenergic beta-1 Receptor Antagonists - pharmacology | Crystallography, X-Ray | Adrenergic beta-1 Receptor Agonists - chemistry | Structure-Activity Relationship | Receptors, Adrenergic, beta-1 - chemistry | Adrenergic beta-1 Receptor Agonists - pharmacology | Turkeys | Adrenergic beta-1 Receptor Antagonists - chemistry | Drug Design | Adrenergic beta-1 Receptor Antagonists - metabolism | Dobutamine - chemistry | Isoproterenol - chemistry | Binding Sites | Hydroxyquinolines - pharmacology | Amphetamines - chemistry | Drug Partial Agonism | Albuterol - metabolism | Hydroxyquinolines - metabolism | Isoproterenol - metabolism | Models, Molecular | Receptors, Adrenergic, beta-1 - metabolism | Serine - chemistry | Serine - metabolism | Dobutamine - pharmacology | Animals | Hydrogen Bonding | Amphetamines - metabolism | Isoproterenol - pharmacology | Protein Stability - drug effects | Albuterol - chemistry | Ligands | Protein Conformation | Adrenergic beta-1 Receptor Agonists - metabolism
Journal Article
Structure, ISSN 0969-2126, 05/2012, Volume 20, Issue 5, pp. 841 - 849
Journal Article
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 05/2015, Volume 55, Issue 5, pp. 1045 - 1061
Journal Article
FASEB Journal, ISSN 0892-6638, 01/2015, Volume 29, Issue 1, pp. 286 - 299
Journal Article
Journal of applied physiology (Bethesda, Md. : 1985), ISSN 8750-7587, 08/2017, Volume 123, Issue 2, pp. 337 - 343
Journal Article
Nature Communications, ISSN 2041-1723, 04/2017, Volume 8, Issue 1, p. 14780
Journal Article
Europace, ISSN 1099-5129, 07/2017, Volume 19, Issue 7, pp. 1211 - 1219
Postural tachycardia syndrome (POTS), a common and debilitating cardiovascular disorder, is characterized by an exaggerated heart rate increase during... 
Autoimmunity | Adrenergic receptors | Postural tachycardia syndrome | Allosteric activation | Vasovagal syncope | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | SYNCOPE | INAPPROPRIATE SINUS TACHYCARDIA | ORTHOSTATIC INTOLERANCE | NITROGLYCERIN | HYPOTENSION | CONSENSUS STATEMENT | Receptors, Adrenergic, alpha-1 - metabolism | Cricetulus | Immunoglobulin G - blood | Autoantibodies - blood | Humans | Male | Receptors, Adrenergic, beta-2 - immunology | Receptors, Adrenergic, beta-2 - drug effects | Adrenergic beta-1 Receptor Agonists - pharmacology | Case-Control Studies | Adrenergic alpha-1 Receptor Agonists - pharmacology | Adrenergic beta-2 Receptor Agonists - pharmacology | Receptors, Adrenergic, alpha-1 - immunology | Dose-Response Relationship, Drug | Young Adult | Transfection | Receptors, Adrenergic, beta-1 - immunology | Adult | Female | Receptors, Adrenergic, beta-1 - drug effects | CHO Cells | Postural Orthostatic Tachycardia Syndrome - immunology | Receptors, Adrenergic, alpha-1 - drug effects | Receptors, Adrenergic, beta-2 - genetics | Rats | Receptors, Adrenergic, beta-1 - metabolism | Abdominal Muscles - blood supply | Arterioles - drug effects | Vasoconstriction - drug effects | Postural Orthostatic Tachycardia Syndrome - blood | Receptors, Adrenergic, beta-2 - metabolism | Animals | Arterioles - metabolism | Postural Orthostatic Tachycardia Syndrome - diagnosis | Receptors, Adrenergic, alpha-1 - genetics | Adolescent | Receptors, Adrenergic, beta-1 - genetics | In Vitro Techniques | Clinical Research | Editor's Choice | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Immunologi inom det medicinska området | Immunology in the medical area
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0180319
The beta-1 adrenergic receptor (ADRB1) is a promising therapeutic target intrinsically involved in the cognitive deficits and pathological features associated... 
7-TRANSMEMBRANE RECEPTORS | ACTIVATION | INHIBITION | INTERFERON-GAMMA | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | FUNCTIONAL SELECTIVITY | NECROSIS-FACTOR-ALPHA | MICE | B-MEDIATED TRANSCRIPTION | Phenyl Ethers - pharmacokinetics | Cricetulus | Models, Chemical | Humans | Crystallography, X-Ray | Male | Adrenergic beta-1 Receptor Agonists - chemistry | Structure-Activity Relationship | Receptors, Adrenergic, beta-1 - chemistry | Propanolamines - pharmacokinetics | Brain - metabolism | Neurocognitive Disorders - drug therapy | Phenyl Ethers - chemistry | Propanolamines - therapeutic use | Adrenergic beta-1 Receptor Agonists - pharmacokinetics | Molecular Structure | Neurocognitive Disorders - metabolism | CHO Cells | Adrenergic beta-1 Receptor Agonists - therapeutic use | Cricetinae | Magnetic Resonance Spectroscopy | Mice, Inbred C57BL | Cells, Cultured | Alzheimer Disease - drug therapy | Models, Molecular | Receptors, Adrenergic, beta-1 - metabolism | Permeability | Drug Discovery | Rats, Sprague-Dawley | Animals | Phenyl Ethers - therapeutic use | Propanolamines - chemistry | Alzheimer Disease - metabolism | Cell Line, Tumor | Protein Binding | GTP-Binding Proteins - metabolism | Epinephrine | Care and treatment | Receptors | Usage | Cellular signal transduction | Research | Alzheimer's disease | Health aspects | Neuroprotection | Brain | Disorders | Cognitive ability | Cognition | Arrestin | Isoproterenol | Kinases | Neuromodulation | Modulators | Recruitment | Lipopolysaccharides | Signal transduction | Rodents | Tumor necrosis factor-TNF | Neurodegenerative diseases | Pharmacology | Inflammation | b-Arrestin | Pathology | Tumor necrosis factor | Adrenergic receptors | Transduction | In vitro methods and tests
Journal Article