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British Journal of Cancer, ISSN 0007-0920, 03/2017, Volume 116, Issue 7, pp. 937 - 943
Background: Renal cell carcinoma (RCC) is one of the most lethal genitourinary cancers. The presence of androgen receptor (AR) in RCC has recently been shown... 
GPRC6A | GLUCOCORTICOID-RECEPTOR | ONCOLOGY | PATHWAY | PROSTATE-CANCER | RESISTANCE | EXPRESSION | PROGRESSION | Prostatic Neoplasms - metabolism | Prognosis | Apoptosis - drug effects | Humans | Receptors, Androgen - metabolism | Androgens - biosynthesis | Male | Kidney Neoplasms - metabolism | Immunoenzyme Techniques | Prostatic Neoplasms, Castration-Resistant - pathology | Testosterone - metabolism | Abiraterone Acetate - pharmacology | Female | Receptors, Androgen - chemistry | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Carcinoma, Renal Cell - drug therapy | Real-Time Polymerase Chain Reaction | Prostatic Neoplasms - drug therapy | Dihydrotestosterone - metabolism | Phenylthiohydantoin - pharmacology | Prostatic Neoplasms - pathology | Carcinoma, Renal Cell - pathology | RNA, Messenger - genetics | Prostatic Neoplasms, Castration-Resistant - drug therapy | Reverse Transcriptase Polymerase Chain Reaction | Prostatic Neoplasms, Castration-Resistant - metabolism | Blotting, Western | Phenylthiohydantoin - analogs & derivatives | Orchiectomy | Xenograft Model Antitumor Assays | Carcinoma, Renal Cell - metabolism | Animals | Receptors, Androgen - genetics | Mice, Nude | Kidney Neoplasms - pathology | Cell Proliferation - drug effects | Mice | Kidney Neoplasms - drug therapy | Index Medicus | renal cell carcinoma | androgen | androgen receptor | Molecular Diagnostics | intracrine | abiraterone acetate | enzalutamide
Journal Article
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2014, Volume 184, Issue 8, pp. 2163 - 2173
Journal Article
Cancer Research, ISSN 0008-5472, 05/2018, Volume 78, Issue 9, pp. 2205 - 2218
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 09/2014, Volume 143, pp. 19 - 28
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, pp. 35354 - 35354
Journal Article
Investigational New Drugs, ISSN 0167-6997, 10/2014, Volume 32, Issue 5, pp. 995 - 1004
Background: ASP9521 is a first-in-class orally available inhibitor of the enzyme 17 β-hydroxysteroid dehydrogenase type 5 (17 βHSD5; AKR1C3), catalysing the... 
Castration-resistant prostate cancer | Testosterone | Androgen deprivation therapy | Medicine & Public Health | Androgen synthesis | AKR1C3 | Oncology | Pharmacology/Toxicology | 17beta-hydroxysteroid dehydrogenase type 5 | ONCOLOGY | DEPRIVATION | GUIDELINES | RECEPTOR | PHARMACOLOGY & PHARMACY | DIHYDROTESTOSTERONE | Cell Count | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Prostatic Neoplasms, Castration-Resistant - pathology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Piperidines - pharmacology | Antineoplastic Agents - adverse effects | Dihydrotestosterone - blood | Indoles - pharmacology | Piperidines - pharmacokinetics | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Kallikreins - blood | Testosterone - blood | Androgen Antagonists - pharmacokinetics | Prostatic Neoplasms, Castration-Resistant - blood | Androgen Antagonists - pharmacology | Treatment Outcome | Prostatic Neoplasms, Castration-Resistant - drug therapy | Prostate-Specific Antigen - blood | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Indoles - adverse effects | Aldo-Keto Reductase Family 1 Member C3 | Piperidines - therapeutic use | Piperidines - adverse effects | Androgen Antagonists - therapeutic use | Indoles - pharmacokinetics | Indoles - therapeutic use | Aged | Androgen Antagonists - adverse effects | Complications and side effects | Care and treatment | Patient outcomes | Androgen suppression therapy | Research | Prostate cancer | Health aspects | Studies | Androgens | Analysis | Pharmacology | Metastasis | Cancer therapies | Index Medicus
Journal Article
Journal Article
Journal Article