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1. Full Text Effective Targeting of Multiple B-Cell Maturation Antigen–Expressing Hematological Malignances by Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor T Cells
by Friedman, Kevin M and Garrett, Tracy E and Evans, John W and Horton, Holly M and Latimer, Howard J and Seidel, Stacie L and Horvath, Christopher J and Morgan, Richard A
Human gene therapy, ISSN 1043-0342, 05/2018, Volume 29, Issue 5, pp. 585 - 601
Research Articles | gene therapy | multiple myeloma | BCMA | CAR | adoptive cell therapy | immunotherapy | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Hematologic Neoplasms - therapy | Humans | Hematologic Neoplasms - pathology | Tumor Necrosis Factor Receptor Superfamily, Member 9 - genetics | Multiple Myeloma - therapy | CD3 Complex - genetics | T-Lymphocytes - drug effects | Lentivirus - genetics | Gene Expression Regulation, Neoplastic - drug effects | Cytotoxicity, Immunologic - drug effects | B-Cell Maturation Antigen - antagonists & inhibitors | B-Cell Maturation Antigen - immunology | Immunotherapy, Adoptive | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | Xenograft Model Antitumor Assays | Receptors, Chimeric Antigen - therapeutic use | Multiple Myeloma - pathology | Animals | Receptors, Chimeric Antigen - immunology | CD3 Complex - immunology | Cell Line, Tumor | T-Lymphocytes - immunology | Hematologic Neoplasms - genetics | Mice | Hematologic Neoplasms - immunology | Multiple Myeloma - genetics | Biotechnology | Animal models | Intravenous administration | Leukemia | Multiple myeloma | Lymphocytes T | Receptors | Lymphocytes | Peripheral blood | Antigens | Chronic lymphatic leukemia | CD137 antigen | Hematology | Maturation | Tumor cells | Therapeutic applications | Pharmacology | Tumor cell lines | Lymphatic leukemia | Lymphoma | Molecular chains | Burkitt's lymphoma | Chimeric antigen receptors | Lymphocytes B | Mantle cell lymphoma | Plasma cells | Tumors | Index Medicus
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2. Janeway's immunobiology
by Murphy, Kenneth and Weaver, Casey
2017, 9th edition., ISBN 9780815345053, xx, 904 pages
Physiopathologie | Système immunitaire | Physiologie | Pathophysiology | Immunotherapy | Physiology | Immunothérapie | Immunity | Immunité | Immune system
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3. Full Text Cracking the BAFF code
by Schneider, Pascal and Mackay, Fabienne
Nature reviews. Immunology, ISSN 1474-1733, 07/2009, Volume 9, Issue 7, pp. 491 - 502
Life Sciences & Biomedicine | Immunology | Science & Technology | B-Cell Maturation Antigen - immunology | Tumor Necrosis Factor Ligand Superfamily Member 13 - immunology | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - immunology | Humans | Toll-Like Receptors - immunology | Tumor Necrosis Factor Ligand Superfamily Member 13 - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Transmembrane Activator and CAML Interactor Protein - metabolism | Signal Transduction - immunology | Lymphocyte Activation - immunology | Animals | B-Cell Activating Factor - metabolism | B-Cell Maturation Antigen - metabolism | B-Lymphocyte Subsets - metabolism | Autoimmunity - immunology | Immune Tolerance - immunology | B-Cell Activating Factor - immunology | B-Lymphocyte Subsets - immunology | Ligands | Toll-Like Receptors - metabolism | Transmembrane Activator and CAML Interactor Protein - immunology | Autoimmunity | Physiological aspects | B cells | Research | Tumor necrosis factor | Risk factors | Index Medicus
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4. Full Text A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens
by Sindhava, Vishal J and Oropallo, Michael A and Moody, Krishna and Naradikian, Martin and Higdon, Lauren E and Zhou, Lin and Myles, Arpita and Green, Nathaniel and Nündel, Kerstin and Stohl, William and Schmidt, Amanda M and Cao, Wei and Dorta-Estremera, Stephanie and Kambayashi, Taku and Marshak-Rothstein, Ann and Cancro, Michael P
The Journal of clinical investigation, ISSN 0021-9738, 05/2017, Volume 127, Issue 5, pp. 1651 - 1663
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Toll-Like Receptor 9 - genetics | Male | T-Box Domain Proteins - immunology | G1 Phase Cell Cycle Checkpoints - immunology | MAP Kinase Signaling System - immunology | Toll-Like Receptor 9 - immunology | Cell Differentiation - genetics | Interleukins - genetics | MAP Kinase Signaling System - genetics | Interleukins - immunology | B-Cell Activating Factor - immunology | Female | CD40 Antigens - genetics | Interferon-gamma - genetics | Cell Line | DNA - immunology | p38 Mitogen-Activated Protein Kinases - genetics | p38 Mitogen-Activated Protein Kinases - immunology | T-Box Domain Proteins - genetics | G1 Phase Cell Cycle Checkpoints - genetics | Receptors, Antigen, B-Cell - immunology | Mice, Knockout | Cell Differentiation - immunology | Animals | B-Lymphocytes - immunology | B-Cell Activating Factor - genetics | Interferon-gamma - immunology | Antigens - immunology | Receptors, Antigen, B-Cell - genetics | Mice | CD40 Antigens - immunology | Antigens | DNA | Cytokine receptors | TLR9 | Cellular signal transduction | Research | B cells | CD27 antigen | CD40 antigen | Laboratories | B-cell receptor | Kinases | Genotype & phenotype | Mitochondria | Cell activation | Lymphocytes | Cell cycle | Interleukin 21 | Toll-like receptors | Deoxyribonucleic acid--DNA | Immunization | Cell survival | Cytokines | Cell division | T cell receptors | Survival | TLR9 protein | Immune response (humoral) | Medicine | Lymphocytes B | BLyS protein | Ligands | Interferon | Regulation | Autoimmune diseases | Apoptosis | Index Medicus | Abridged Index Medicus
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5. Full Text B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma
by Cohen, Adam D and Cohen, Adam D and Garfall, Alfred L and Garfall, Alfred L and Stadtmauer, Edward A and Stadtmauer, Edward A and Melenhorst, J. Joseph and Melenhorst, J Joseph and Lacey, Simon F and Lacey, Simon F and Lancaster, Eric and Lancaster, Eric and Vogl, Dan T and Vogl, Dan T and Weiss, Brendan M and Weiss, Brendan M and Dengel, Karen and Dengel, Karen and Nelson, Annemarie and Nelson, Annemarie and Plesa, Gabriela and Plesa, Gabriela and Chen, Fang and Chen, Fang and Davis, Megan M and Davis, Megan M and Hwang, Wei-Ting and Hwang, Wei-Ting and Young, Regina M and Young, Regina M and Brogdon, Jennifer L and Brogdon, Jennifer L and Isaacs, Randi and Isaacs, Randi and Pruteanu-Malinici, Iulian and Pruteanu-Malinici, Iulian and Siegel, Don L and Siegel, Don L and Levine, Bruce L and Levine, Bruce L and June, Carl H and June, Carl H and Milone, Michael C and Milone, Michael C
The Journal of clinical investigation, ISSN 0021-9738, 03/2019, Volume 129, Issue 6, pp. 2210 - 2221
Cancer immunotherapy | Oncology | Clinical Trials | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cyclophosphamide - administration & dosage | Multiple Myeloma - mortality | Humans | Middle Aged | Neoplasm Proteins - immunology | Male | Multiple Myeloma - immunology | Lymphocyte Depletion | Cyclophosphamide - adverse effects | T-Lymphocytes - transplantation | Multiple Myeloma - therapy | Adult | Female | T-Lymphocytes - pathology | Neoplasm Proteins - genetics | B-Cell Maturation Antigen - immunology | Autografts | Transduction, Genetic | Immunotherapy, Adoptive | Survival Rate | Disease-Free Survival | Receptors, Chimeric Antigen - immunology | Receptors, Chimeric Antigen - genetics | T-Lymphocytes - immunology | Aged | Multiple Myeloma - genetics | Antigens | Chemotherapy | Cyclophosphamide | Pharmaceutical industry | T cells | Cancer | Index Medicus | Abridged Index Medicus
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6. Full Text Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell
by Ruella, Marco and Xu, Jun and Barrett, David M and Fraietta, Joseph A and Reich, Tyler J and Ambrose, David E and Klichinsky, Michael and Shestova, Olga and Patel, Prachi R and Kulikovskaya, Irina and Nazimuddin, Farzana and Bhoj, Vijay G and Orlando, Elena J and Fry, Terry J and Bitter, Hans and Maude, Shannon L and Levine, Bruce L and Nobles, Christopher L and Bushman, Frederic D and Young, Regina M and Scholler, John and Gill, Saar I and June, Carl H and Grupp, Stephan A and Lacey, Simon F and Melenhorst, J. Joseph
Nature medicine, ISSN 1078-8956, 10/2018, Volume 24, Issue 10, pp. 1499 - 1503
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Leukemia - pathology | Humans | Receptors, Antigen, T-Cell - therapeutic use | Leukemia - drug therapy | Receptors, Chimeric Antigen | Male | Drug Resistance, Neoplasm - immunology | Cell- and Tissue-Based Therapy | Epitopes - immunology | Young Adult | B-Lymphocytes - immunology | Leukemia - immunology | Antigens, CD19 - therapeutic use | Adult | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Antigens, CD19 - immunology | Case studies | Complications and side effects | Antigen receptors, T cell | Chemotherapy | Receptors | Relapse | Leukemia | T cells | Health aspects | Cancer | Chimeric antigen receptors | Infusion | CD19 antigen | Lymphocytes B | Lymphocytes | CAR gene | Masking | Lymphocytes T | Index Medicus
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7. Full Text γδ T Cells Recognize a Microbial Encoded B Cell Antigen to Initiate a Rapid Antigen-Specific Interleukin-17 Response
by Zeng, Xun and Wei, Yu-Ling and Huang, Jun and Newell, Evan W and Yu, Hongxiang and Kidd, Brian A and Kuhns, Michael S and Waters, Ray W and Davis, Mark M and Weaver, Casey T and Chien, Yueh-hsiu
Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2012, Volume 37, Issue 3, pp. 524 - 534
Humans | Interleukin-17 - immunology | Male | Receptors, Antigen, T-Cell, gamma-delta - genetics | Flow Cytometry | T-Lymphocytes - metabolism | Algal Proteins - immunology | Base Sequence | Female | Phycoerythrin - metabolism | B-Lymphocytes - metabolism | Amino Acid Sequence | Phycoerythrin - immunology | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interleukin-17 - genetics | Mice, Transgenic | Receptors, Antigen, T-Cell, gamma-delta - immunology | Antigens - metabolism | Binding Sites - genetics | Protein Binding - immunology | Interleukin-17 - metabolism | Animals | B-Lymphocytes - immunology | Antigens - immunology | Mice, Inbred NOD | T-Lymphocytes - immunology | Mice | Kinetics | Algal Proteins - metabolism | Index Medicus
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8. Full Text Target antigen density governs the efficacy of anti-CD20-CD28-CD3 ζ chimeric antigen receptor-modified effector CD8+ T cells
by Watanabe, Keisuke and Terakura, Seitaro and Martens, Anton C and Van Meerten, Tom and Uchiyama, Susumu and Imai, Misa and Sakemura, Reona and Goto, Tatsunori and Hanajiri, Ryo and Imahashi, Nobuhiko and Shimada, Kazuyuki and Tomita, Akihiro and Kiyoi, Hitoshi and Nishida, Tetsuya and Naoe, Tomoki and Murata, Makoto
The Journal of immunology (1950), ISSN 0022-1767, 02/2015, Volume 194, Issue 3, pp. 911 - 920
Humans | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Intracellular Space | Lymphoma, B-Cell - genetics | CD28 Antigens - metabolism | T-Cell Antigen Receptor Specificity - genetics | T-Cell Antigen Receptor Specificity - immunology | Lymphoma, B-Cell - immunology | Antigens, Surface - metabolism | CD8-Positive T-Lymphocytes - metabolism | Gene Order | Leukemia, Lymphocytic, Chronic, B-Cell - immunology | Genes, Reporter | Lymphoma, B-Cell - drug therapy | Recombinant Proteins - metabolism | Antigens, CD20 - immunology | T-Lymphocyte Subsets | Gene Expression | Lymphoma, B-Cell - metabolism | Transduction, Genetic | Receptors, Antigen, T-Cell - metabolism | Signal Transduction | Lymphocyte Activation | Rituximab | Immunophenotyping | CD28 Antigens - immunology | Recombinant Proteins - genetics | Antigens, CD20 - metabolism | CD3 Complex - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | CD3 Complex - immunology | Cell Line, Tumor | Protein Binding | Receptors, Antigen, T-Cell - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | CD8-Positive T-Lymphocytes - immunology | Antigens, Surface - immunology | Cytokines - biosynthesis | Antibodies, Monoclonal, Murine-Derived - therapeutic use | Cytotoxicity, Immunologic | Index Medicus | Abridged Index Medicus
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9. Full Text Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor
by Kochenderfer, James N and Dudley, Mark E and Kassim, Sadik H and Somerville, Robert P. T and Carpenter, Robert O and Maryalice, Stetler-Stevenson and Yang, James C and Phan, Giao Q and Hughes, Marybeth S and Sherry, Richard M and Raffeld, Mark and Feldman, Steven and Lu, Lily and Li, Yong F and Ngo, Lien T and Goy, Andre and Feldman, Tatyana and Spaner, David E and Wang, Michael L and Chen, Clara C and Kranick, Sarah M and Nath, Avindra and Nathan, Debbie-Ann N and Morton, Kathleen E and Toomey, Mary Ann and Rosenberg, Steven A
Journal of clinical oncology, ISSN 0732-183X, 02/2015, Volume 33, Issue 6, pp. 540 - 549
Life Sciences & Biomedicine | Oncology | Science & Technology | Cyclophosphamide - administration & dosage | Immunotherapy, Adoptive - methods | Lymphoma, Large B-Cell, Diffuse - drug therapy | Humans | Lymphoma, B-Cell - therapy | Middle Aged | Male | Combined Modality Therapy | Vidarabine - analogs & derivatives | T-Lymphocytes - transplantation | Lymphoma, Large B-Cell, Diffuse - therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Lymphoma, B-Cell - immunology | Lymphoma, Large B-Cell, Diffuse - immunology | Adult | Female | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Aged | Vidarabine - administration & dosage | Transplantation Conditioning - methods | Antigens, CD19 - immunology | Lymphoma, B-Cell - drug therapy | Index Medicus | Hema17 | Hema8 | Hema16 | To6 | ORIGINAL REPORTS | Hema9
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