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Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 06/2006, Volume 176, Issue 11, pp. 6752 - 6761
Tryptophan catabolism is a tolerogenic effector system in regulatory T cell function, yet the general mechanisms whereby tryptophan catabolism affects T cell... 
IMMUNE-RESPONSE | INHIBITION | DENDRITIC CELLS | NONOBESE DIABETIC MICE | TRANSCRIPTION FACTOR FOXP3 | INDOLEAMINE 2,3-DIOXYGENASE | IN-VIVO | PERIPHERAL TOLERANCE | PROLIFERATION | IMMUNOLOGY | ANTIGEN | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | CD8-Positive T-Lymphocytes - pathology | Coculture Techniques | Protein-Serine-Threonine Kinases | Receptors, Antigen, T-Cell - antagonists & inhibitors | Tryptophan - metabolism | Interleukin-10 - physiology | Receptors, Antigen, T-Cell - biosynthesis | T-Lymphocytes, Regulatory - immunology | Forkhead Transcription Factors - metabolism | CD8-Positive T-Lymphocytes - metabolism | Female | Mice, Inbred DBA | Kynurenine - metabolism | Forkhead Transcription Factors - biosynthesis | Receptors, Interleukin-2 - biosynthesis | Kynurenine - pharmacology | Cells, Cultured | Transforming Growth Factor beta - physiology | Receptors, Interleukin-2 - metabolism | Immunophenotyping | Mice, Transgenic | Mice, SCID | Antigens, Differentiation - physiology | Mice, Knockout | CTLA-4 Antigen | Membrane Proteins - biosynthesis | Animals | T-Lymphocyte Subsets - pathology | Membrane Proteins - antagonists & inhibitors | Down-Regulation - immunology | T-Lymphocyte Subsets - metabolism | Protein Kinases - physiology | Resting Phase, Cell Cycle - immunology | Tryptophan - physiology | Mice, Inbred NOD | Mice | CD8-Positive T-Lymphocytes - immunology | Antigens, CD
Journal Article
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 01/2004, Volume 172, Issue 1, pp. 104 - 113
Chimeric receptors that include CD28 signaling in series with TCRzeta in the same receptor have been demonstrated to activate prestimulated human primary T... 
RESPONSES | 4-1BB LIGAND | CYTOKINE PRODUCTION | IN-VIVO | FACTOR-KAPPA-B | MOLECULAR-CLONING | ANTITUMOR IMMUNITY | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | ICOS | EXPRESSION | Mutagenesis, Insertional - methods | Humans | Interphase - immunology | Receptors, Tumor Necrosis Factor - physiology | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | CD28 Antigens - genetics | Membrane Proteins - physiology | CD28 Antigens - physiology | Receptors, Nerve Growth Factor - biosynthesis | Receptors, Antigen, T-Cell - metabolism | Membrane Proteins - genetics | Signal Transduction - genetics | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Receptors, Antigen, T-Cell - physiology | Intracellular Fluid - enzymology | Membrane Proteins - biosynthesis | Tyrosine - metabolism | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Mice | Receptors, Antigen, T-Cell - genetics | Antigens, Differentiation, T-Lymphocyte - biosynthesis | Antigens, CD | Inducible T-Cell Co-Stimulator Protein | T-Lymphocyte Subsets - immunology | Phosphorylation | Recombinant Fusion Proteins - physiology | Receptors, Nerve Growth Factor - physiology | Phosphatidylinositol 3-Kinases - metabolism | Receptors, OX40 | Tumor Necrosis Factor Receptor Superfamily, Member 9 | Receptors, Antigen, T-Cell - biosynthesis | Signal Transduction - immunology | Transfection | Antigens, Differentiation, T-Lymphocyte - physiology | Membrane Proteins - metabolism | Cytotoxicity Tests, Immunologic - methods | Intracellular Fluid - metabolism | Receptors, Tumor Necrosis Factor - genetics | Recombinant Fusion Proteins - biosynthesis | Cells, Cultured | Receptors, Nerve Growth Factor - genetics | Animals | T-Lymphocyte Subsets - enzymology | T-Lymphocyte Subsets - metabolism | Antigens, Differentiation, T-Lymphocyte - genetics | CD28 Antigens - biosynthesis | Receptors, Tumor Necrosis Factor - biosynthesis | Cytokines - biosynthesis
Journal Article
Cancer Research, ISSN 0008-5472, 08/2004, Volume 64, Issue 16, pp. 5839 - 5849
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2009, Volume 183, Issue 9, pp. 5563 - 5574
To generate chimeric Ag receptors (CARs) for the adoptive immunotherapy of cancer patients with ErbB2-expressing tumors, a single-chain Ab derived from the... 
EX-VIVO EXPANSION | BREAST-CANCER | METASTATIC MELANOMA | 4-1BB LIGAND | CYTOTOXIC LYMPHOCYTES | IN-VIVO | EFFECTOR FUNCTION | MONOCLONAL-ANTIBODY | GENE-THERAPY | IMMUNOLOGY | ADOPTIVE CELL TRANSFER | Mammary Neoplasms, Experimental - immunology | T-Lymphocyte Subsets - immunology | Receptor, ErbB-2 - genetics | Antineoplastic Agents - chemical synthesis | Coculture Techniques | Humans | Recombinant Fusion Proteins - therapeutic use | Receptors, Antigen, T-Cell - therapeutic use | Cell Survival - genetics | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Receptors, Antigen, T-Cell - biosynthesis | Antibodies, Monoclonal, Humanized | Signal Transduction - immunology | Mammary Neoplasms, Experimental - pathology | Receptor, ErbB-2 - immunology | Tumor Cells, Cultured | Cell Line | Immunotherapy, Adoptive - methods | Receptor, ErbB-2 - biosynthesis | Transduction, Genetic | Gene Expression Regulation, Neoplastic - immunology | Recombinant Fusion Proteins - chemical synthesis | Protein Structure, Tertiary - genetics | Signal Transduction - genetics | Cell Survival - immunology | Mice, SCID | T-Lymphocyte Subsets - transplantation | Mammary Neoplasms, Experimental - therapy | Antibodies, Monoclonal - genetics | Animals | T-Lymphocyte Subsets - metabolism | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Mice | Receptors, Antigen, T-Cell - genetics | Trastuzumab
Journal Article
Science Translational Medicine, ISSN 1946-6234, 11/2014, Volume 6, Issue 261, pp. 261ra151 - 261ra151
Translating the recent success of chimeric antigen receptor (CAR) T cell therapy for hematological malignancies to solid tumors will necessitate overcoming... 
MEDICINE, RESEARCH & EXPERIMENTAL | LOCALIZATION | OVEREXPRESSION | CHIMERIC ANTIGEN RECEPTORS | ADENOCARCINOMAS | HIGH-AFFINITY | MONOCLONAL-ANTIBODY | ANTITUMOR-ACTIVITY | EXPRESSION | CANCER | LYMPHOCYTES | CELL BIOLOGY | Mesothelioma - immunology | Pleural Neoplasms - genetics | Cell Proliferation | Mesothelioma - pathology | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Receptors, Antigen, T-Cell - biosynthesis | CD4-Positive T-Lymphocytes - immunology | Pleural Neoplasms - metabolism | Time Factors | HEK293 Cells | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Receptors, Antigen, T-Cell - immunology | Cell Differentiation | Pleural Neoplasms - pathology | Lung Neoplasms - genetics | Immunotherapy, Adoptive - methods | Mesothelioma - therapy | Pleural Neoplasms - immunology | Transduction, Genetic | Lymphocyte Activation | CD4-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - transplantation | Lung Neoplasms - therapy | Mesothelioma - genetics | Mice, SCID | Pleural Neoplasms - therapy | GPI-Linked Proteins - metabolism | Xenograft Model Antitumor Assays | Lung Neoplasms - immunology | Animals | Mesothelioma - metabolism | CD4-Positive T-Lymphocytes - transplantation | Cell Line, Tumor | Mice, Inbred NOD | Receptors, Antigen, T-Cell - genetics | Chimerism | Cytotoxicity, Immunologic | Genetic Therapy - methods | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 06/2001, Volume 61, Issue 12, pp. 4766 - 4772
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