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Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7547, pp. 373 - 377
Journal Article
The Journal of Immunology, ISSN 0022-1767, 01/2007, Volume 178, Issue 1, pp. 320 - 329
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2012, Volume 130, Issue 7, pp. 1577 - 1589
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2011, Volume 29, Issue 18, pp. 2493 - 2498
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2016, Volume 22, Issue 8, pp. 1856 - 1864
In the context of chronic antigen exposure in chronic viral infections and cancer, T cells become exhausted/dysfunctional. These exhausted T cells exhibit... 
LUNG-CANCER | INHIBITORY CHECKPOINTS | ONCOLOGY | CHAIN CYTOKINES IL-2 | INDOLEAMINE 2,3-DIOXYGENASE | EFFECTOR FUNCTION | REGULATORY T | MELANOMA PATIENTS | CHRONIC VIRAL-INFECTION | TUMOR MICROENVIRONMENT | PD-1 EXPRESSION | Neoplasms - metabolism | Immunomodulation - drug effects | Epigenesis, Genetic | Humans | Antibodies, Monoclonal - therapeutic use | Immunomodulation - genetics | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | T-Lymphocytes - metabolism | Myeloid Cells - immunology | T-Lymphocytes - drug effects | Antineoplastic Agents - pharmacology | Costimulatory and Inhibitory T-Cell Receptors - antagonists & inhibitors | Tumor Microenvironment - drug effects | Antigen-Presenting Cells - metabolism | Cytokines - metabolism | Antibodies, Monoclonal - pharmacology | Antigen-Presenting Cells - drug effects | Gene Expression Regulation | CTLA-4 Antigen - metabolism | Programmed Cell Death 1 Receptor - metabolism | Antigen-Presenting Cells - immunology | Neoplasms - drug therapy | Tumor Microenvironment - immunology | Animals | Signal Transduction - drug effects | Neoplasms - immunology | Costimulatory and Inhibitory T-Cell Receptors - metabolism | Myeloid Cells - metabolism | T-Lymphocytes - immunology | CTLA-4 Antigen - antagonists & inhibitors | Immunologic Factors - metabolism | Neoplasms - pathology
Journal Article
Immunity, ISSN 1074-7613, 10/2009, Volume 31, Issue 4, pp. 632 - 642
Cytolytic granules mediate killing of virus-infected cells by cytotoxic T lymphocytes. We show here that the granules can take long or short paths to the... 
MOLIMMUNO | CELLIMMUNO | TARGET-CELL | SUPRAMOLECULAR ACTIVATION CLUSTERS | RING JUNCTION | EFFECTOR FUNCTIONS | MICROTUBULE-ORGANIZING CENTER | CLASS-I | IMMUNOLOGY | IMMUNOLOGICAL SYNAPSE | EX-VIVO | POLARIZATION | LYMPHOCYTES-T | Calcium - metabolism | Humans | Calcium - immunology | Microtubule-Organizing Center - drug effects | Immunological Synapses - metabolism | Receptors, Antigen, T-Cell - drug effects | Signal Transduction - immunology | T-Lymphocytes, Cytotoxic - drug effects | Microtubules - metabolism | Microtubules - drug effects | Cytoplasmic Granules - metabolism | Calcium Signaling - immunology | Receptors, Antigen, T-Cell - immunology | Biological Transport - drug effects | Cell Polarity - drug effects | Cytotoxicity, Immunologic - drug effects | Ionophores - pharmacology | Microtubule-Organizing Center - metabolism | T-Lymphocytes, Cytotoxic - immunology | Cell Line | Cell Polarity - immunology | Receptors, Antigen, T-Cell - metabolism | Cytoplasmic Granules - drug effects | Microtubules - immunology | Biological Transport - immunology | Cell Degranulation - immunology | Immunological Synapses - drug effects | Microtubule-Organizing Center - immunology | Signal Transduction - drug effects | T-Lymphocytes, Cytotoxic - metabolism | Calcium Signaling - drug effects | Immunological Synapses - immunology | Ionomycin - pharmacology | Cytotoxicity, Immunologic - immunology | Cytoplasmic Granules - immunology | T-Lymphocytes, Cytotoxic - cytology | Cell Degranulation - drug effects | T cells | Ligands | T cell receptors | Peptides | Efficiency
Journal Article
BLOOD, ISSN 0006-4971, 11/2011, Volume 118, Issue 18, pp. 4853 - 4862
Journal Article
Journal Article