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1. Full Text Atrial Natriuretic Peptide Frameshift Mutation in Familial Atrial Fibrillation
by Hodgson-Zingman, Denice M and Karst, Margaret L and Zingman, Leonid V and Heublein, Denise M and Darbar, Dawood and Herron, Kathleen J and Ballew, Jeffrey D and de Andrade, Mariza and Burnett, John C and Olson, Timothy M
The New England Journal of Medicine, ISSN 0028-4793, 07/2008, Volume 359, Issue 2, pp. 158 - 165
In a family with hereditary atrial fibrillation, linkage analysis and candidate-gene sequencing identified a frameshift mutation in the atrial natriuretic... 
SHATTUCK-LECTURE | OF-FUNCTION MUTATION | MEDICINE, GENERAL & INTERNAL | RISK | RECEPTORS | HEART-FAILURE | European Continental Ancestry Group - genetics | Frameshift Mutation | Atrial Natriuretic Factor - metabolism | Signal Transduction | Humans | Middle Aged | Male | Chromosome Mapping | Atrial Fibrillation - genetics | Atrial Fibrillation - physiopathology | Action Potentials | Atrial Fibrillation - metabolism | Animals | Chromosomes, Human, Pair 1 | DNA Mutational Analysis | Guanosine Monophosphate - metabolism | Pedigree | Atrial Natriuretic Factor - genetics | Adult | Female | Care and treatment | Usage | Atrial fibrillation | Analysis | Radioimmunoassay | Development and progression | Genetic aspects | Mutation (Biology)
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2. Full Text Atrial Natriuretic Peptide　― Old But New Therapeutic in Cardiovascular Diseases
by Ichiki, Tomoko and Burnett Jr, John C
Circulation Journal, ISSN 1346-9843, 2017, Volume 81, Issue 7, pp. 913 - 919
With the discovery of atrial natriuretic peptide (ANP), the heart as an endocrine organ was established. Basic science revealed that ANP, through the... 
Cardiorenal biology | cGMP | Atrial natriuretic peptide | CARDIAC & CARDIOVASCULAR SYSTEMS | GENERAL COMMUNITY | INSULIN-DEGRADING ENZYME | SPONTANEOUSLY HYPERTENSIVE-RATS | BLOOD-PRESSURE | CARDIAC FIBROBLASTS | IN-VITRO | DECOMPENSATED HEART-FAILURE | SERINE-PROTEASE | GENETIC VARIANT | CORIN | Atrial Natriuretic Factor - metabolism | Protein Engineering - methods | Humans | Heart Failure - genetics | Heart Failure - metabolism | Neprilysin - metabolism | Receptors, Guanylate Cyclase-Coupled - metabolism | Heart Failure - drug therapy | Genetic Variation | Proteolysis - drug effects | Atrial Natriuretic Factor - therapeutic use | Atrial Natriuretic Factor - genetics | Drug Design | Neprilysin - antagonists & inhibitors | Neprilysin - genetics | Protease Inhibitors - therapeutic use | Receptors, Guanylate Cyclase-Coupled - genetics
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3. Full Text Atrial Natriuretic Peptide Genetic Variant rs5065 and Risk for Cardiovascular Disease in the General Community: A 9-Year Follow-Up Study
by Cannone, Valentina and Huntley, Brenda K and Olson, Timothy M and Heublein, Denise M and Scott, Christopher G and Bailey, Kent R and Redfield, Margaret M and Rodeheffer, Richard J and Burnett, John C
Hypertension, ISSN 0194-911X, 11/2013, Volume 62, Issue 5, pp. 860 - 865
We analyzed the phenotype associated with the atrial natriuretic peptide (ANP) genetic variant rs5065 in a random community-based sample. We also assessed and... 
natriuretic peptidesstroke | atrial natriuretic peptides | cardiovascular diseases | natriuretic peptides | POLYMORPHISMS | MOLECULAR VARIANT | RECEPTOR | PERIPHERAL VASCULAR DISEASE | HYPERTENSION | stroke | ASSOCIATION | ENDOTHELIAL PERMEABILITY | Genetic Predisposition to Disease | Permeability - drug effects | Second Messenger Systems - drug effects | Prevalence | Cardiovascular Diseases - metabolism | Follow-Up Studies | Endothelial Cells - metabolism | Gene Frequency | Humans | Genotype | Male | Risk | Cardiovascular Diseases - genetics | Receptors, Guanylate Cyclase-Coupled - metabolism | Cyclic GMP - metabolism | Atrial Natriuretic Factor - genetics | Second Messenger Systems - genetics | Alleles | Cardiovascular Diseases - epidemiology | Female | Polymorphism, Single Nucleotide | Atrial Natriuretic Factor - pharmacology | Endothelial Cells - drug effects
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4. Full Text Atrial natriuretic peptide and type 2 diabetes development - Biomarker and genotype association study
by Jujić, Amra and Nilsson, Peter M and Engström, Gunnar and Hedblad, Bo and Melander, Olle and Magnusson, Martin and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Kardiovaskulär forskning - epidemiologi and Lund University and Internmedicin - epidemiologi and EpiHealth: Epidemiology for Health and Internal Medicine - Epidemiology and Cardiovascular Research - Epidemiology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e89201
Background: We have recently shown that low plasma levels of mid-regional atrial natriuretic peptide (MR-ANP) predict development of diabetes and glucose... 
PROSPECTIVE MALMO DIET | METABOLIC SYNDROME | RISK-FACTORS | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | RECEPTOR | ANGIOTENSIN-II | GENETIC VARIANT | BLOOD-PRESSURE | HYPERTENSIVE PATIENTS | Body Mass Index | Age Factors | Diabetes Mellitus, Type 2 - genetics | Humans | Proportional Hazards Models | Genotype | Male | Diabetes Mellitus, Type 2 - metabolism | Sweden - epidemiology | Atrial Natriuretic Factor - blood | Diabetes Mellitus, Type 2 - epidemiology | Regression Analysis | Atrial Natriuretic Factor - genetics | Sex Factors | Polymorphism, Single Nucleotide - genetics | Female | Type 2 diabetes | Analysis | Oncology, Experimental | Development and progression | Genetic aspects | Research | Single nucleotide polymorphisms | Glucose | Risk factors | Dextrose | Natriuretic peptides | Cancer | Plasma | Peptides | Regional development | Cardiovascular disease | Emergency medical care | Atrial natriuretic peptide | Single-nucleotide polymorphism | Gene polymorphism | Etiology | Rodents | Population | Physiology | Bioindicators | Public health | Heart failure | Hypertension | Fasting | Diabetes mellitus | Health risks | Regression analysis | Risk analysis | Loci | Studies | Hospitals | Body mass | Biomarkers | Insulin resistance | Plasma levels | Diabetes | Polymorphism | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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5. Full Text Granulosa Cell Ligand NPPC and Its Receptor NPR2 Maintain Meiotic Arrest in Mouse Oocytes
by Meijia Zhang and You-Qiang Su and Koji Sugiura and Guoliang Xia and John J. Eppig
Science, ISSN 0036-8075, 10/2010, Volume 330, Issue 6002, pp. 366 - 369
Granulosa cells of mammalian Graafian follicles maintain oocytes in meiotic arrest, which prevents their precocious maturation. We show that mouse mural... 
Receptors | Messenger RNA | Germ cells | Murals | Somatic cells | REPORTS | Granulosa cells | Meiosis | Ovaries | Follicles | Oocytes | NATRIURETIC-PEPTIDE | VITRO | OVARY | CYCLIC-GMP | FOLLICLES | MULTIDISCIPLINARY SCIENCES | CUMULUS CELLS | GPR3 | MATURATION | BMP15 | Protein Precursors - genetics | Signal Transduction | Receptors, Atrial Natriuretic Factor - metabolism | RNA, Messenger - genetics | RNA, Messenger - metabolism | Granulosa Cells - metabolism | Protein Precursors - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Animals | Oocytes - physiology | Cyclic GMP - metabolism | Natriuretic Peptide, C-Type - metabolism | Cumulus Cells - metabolism | Models, Biological | Receptors, Atrial Natriuretic Factor - genetics | Female | Ligands | Natriuretic Peptide, C-Type - genetics | Mice | Mutation | Ovarian Follicle - cytology | Cyclic AMP - metabolism | Research | Properties | Ligands (Biochemistry) | Cell division | Animal reproduction | Biochemistry | Peptides | Rodents
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6. Full Text Heterozygous Mutations in Natriuretic Peptide Receptor‐B (NPR2) Gene as a Cause of Short Stature
by Wang, Sophie R and Jacobsen, Christina M and Carmichael, Heather and Edmund, Aaron B and Robinson, Jerid W and Olney, Robert C and Miller, Timothy C and Moon, Jennifer E and Mericq, Veronica and Potter, Lincoln R and Warman, Matthew L and Hirschhorn, Joel N and Dauber, Andrew
Human Mutation, ISSN 1059-7794, 04/2015, Volume 36, Issue 4, pp. 474 - 481
ABSTRACT Based on the observation of reduced stature in relatives of patients with acromesomelic dysplasia, Maroteaux type (AMDM), caused by homozygous or... 
natriuretic peptide receptor‐B | ISS | short stature | NPR2 | Short stature | Natriuretic peptide receptor-B | TRANSLOCATION | CNP | natriuretic peptide receptor-B | OVEREXPRESSION | OVERGROWTH | GROWTH | GENETICS & HEREDITY | MICE | DWARFISM | GUANYLYL CYCLASE-B | Genetic Association Studies | Receptors, Atrial Natriuretic Factor - metabolism | Gene Frequency | Humans | Child, Preschool | Male | Dwarfism - diagnosis | Sequence Analysis, DNA | Genetic Variation | Dwarfism - genetics | Phenotype | Pedigree | Alleles | Receptors, Atrial Natriuretic Factor - genetics | Female | Heterozygote | Mutation | Child | Dysplasia | Molecular genetics | Analysis | Genes | Genetic aspects | Stature, Short | Natriuretic peptides | Genetic disorders | Peptides | Growth disorders
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7. Full Text Natriuretic peptides enhance the oxidative capacity of human skeletal muscle
by Engeli, Stefan and Birkenfeld, Andreas L and Badin, Pierre-Marie and Bourlier, Virginie and Louche, Katie and Viguerie, Nathalie and Thalamas, Claire and Montastier, Emilie and Larrouy, Dominique and Harant, Isabelle and De Glisezinski, Isabelle and Lieske, Stefanie and Reinke, Julia and Beckmann, Bibiana and Langin, Dominique and Jordan, Jens and Moro, Cedric
Journal of Clinical Investigation, ISSN 0021-9738, 12/2012, Volume 122, Issue 12, pp. 4675 - 4679
Cardiac natriuretic peptides (NP) are major activators of human fat cell lipolysis and have recently been shown to control brown fat thermogenesis. Here, we... 
MEDICINE, RESEARCH & EXPERIMENTAL | OBESITY | LIPOLYSIS | PGC-1 COACTIVATORS | RESTING METABOLIC-RATE | ENERGY-METABOLISM | HUMAN ADIPOCYTES | Adaptation, Physiological | Up-Regulation | Humans | Mitochondria, Muscle - metabolism | Male | Muscle, Skeletal - metabolism | Muscle Fibers, Skeletal - metabolism | Natriuretic Peptide, Brain - physiology | Atrial Natriuretic Factor - physiology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Adult | Obesity | Oxidation-Reduction | Signal Transduction | Receptors, Atrial Natriuretic Factor - metabolism | Heat-Shock Proteins - metabolism | Cells, Cultured | Gene Expression Regulation | Oxidative Phosphorylation | Oxygen Consumption | Lipid Metabolism | Genes, Mitochondrial | Transcription Factors - metabolism | Receptors, Atrial Natriuretic Factor - genetics | Primary Cell Culture | Physiological aspects | Muscles | Oxidative stress | Exercise | Research | Natriuretic peptides | Brief Report
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8. Full Text Medulloblastoma Comprises Four Distinct Molecular Variants
by Paul A. Northcott and Andrey Korshunov and Hendrik Witt and Thomas Hielscher and Charles G. Eberhart and Stephen Mack and Eric Bouffet and Steven C. Clifford and Cynthia E. Hawkins and Pim French and James T. Rutka and Stefan Pfister and Michael D. Taylor
Journal of Clinical Oncology, ISSN 0732-183X, 04/2011, Volume 29, Issue 11, pp. 1408 - 1414
Purpose Recent genomic approaches have suggested the existence of multiple distinct subtypes of medulloblastoma. We studied a large cohort of medulloblastomas... 
SURVIVAL | PREDICTS | DISEASE RISK | ONCOLOGY | BETA-CATENIN STATUS | MYC | CHILDHOOD MEDULLOBLASTOMA | GENE-EXPRESSION | CANCER | STRATIFICATION | CHEMOTHERAPY | Immunohistochemistry | Kv1.1 Potassium Channel - genetics | Prognosis | Signal Transduction | Membrane Proteins - genetics | Genomics | Humans | Intercellular Signaling Peptides and Proteins - genetics | Survival Rate | Gene Expression Profiling | Cerebellar Neoplasms - genetics | Disease Progression | beta Catenin - genetics | Analysis of Variance | DNA Mutational Analysis | Medulloblastoma - pathology | Receptors, Atrial Natriuretic Factor - genetics | Transcription, Genetic | Software | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Child | Principal Component Analysis | Pedi4 | ORIGINAL REPORTS | Neur1
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9. Full Text Molecular Biology of the Natriuretic Peptide System: Implications for Physiology and Hypertension
by Gardner, David G and Chen, Songcang and Glenn, Denis J and Grigsby, Chris L
Hypertension, ISSN 0194-911X, 03/2007, Volume 49, Issue 3, pp. 419 - 426
CARDIAC TRANSCRIPTION FACTORS | BLOOD-VOLUME EXPANSION | MEDULLARY COLLECTING DUCT | ACTIVATED PROTEIN-KINASE | SALT-SENSITIVE HYPERTENSION | PRESSURE-INDEPENDENT ENHANCEMENT | PERIPHERAL VASCULAR DISEASE | GUANYLYL CYCLASE-A | SIGNAL-REGULATED KINASE | MICE LACKING | BNP GENE-TRANSCRIPTION | Atrial Natriuretic Factor - physiology | Natriuretic Peptide, Brain - genetics | Natriuretic Peptides - physiology | Atrial Natriuretic Factor - genetics | Humans | Gene Expression Regulation | Receptors, Atrial Natriuretic Factor - genetics | Transcription, Genetic | Natriuretic Peptide, Brain - physiology | Hypertension - physiopathology | Natriuretic Peptides - genetics | Receptors, Atrial Natriuretic Factor - physiology
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10. Full Text Is atrial natriuretic peptide (ANP) and natriuretic peptide receptor-a (NPR-A) expression in human placenta and decidua normal?
by Tan, Hongchuan and Lin, Liang and Huang, Liping and Yu, Yanhong
Medical Science Monitor, ISSN 1234-1010, 2019, Volume 25, pp. 2868 - 2878
Background: Atrial natriuretic peptide (ANP) is a cardiac hormone that regulates blood pressure and the salt-water balance in the blood. It acts through... 
Pre-Eclampsia | Trophoblasts | Placenta | Decidua | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | PREECLAMPSIA | PREGNANCY | PATHOGENESIS | INVASION | INHIBITION | GROWTH | SUPPRESSES | Immunohistochemistry | Pre-Eclampsia - genetics | Receptors, Atrial Natriuretic Factor - biosynthesis | Cell Line | Atrial Natriuretic Factor - biosynthesis | Atrial Natriuretic Factor - metabolism | Decidua - cytology | Receptors, Atrial Natriuretic Factor - metabolism | Humans | Cell Proliferation - physiology | Gene Expression Profiling - methods | Pre-Eclampsia - pathology | Pregnancy Trimester, First | Blotting, Western | Decidua - metabolism | Placenta - metabolism | Pregnancy | Young Adult | Placenta - cytology | Atrial Natriuretic Factor - genetics | Receptors, Atrial Natriuretic Factor - genetics | Adult | Female | Apoptosis - physiology
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11. Full Text Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A
by Holtwick, Rita and Van Eickels, Martin and Skryabin, Boris V and Baba, Hideo A and Bubikat, Alexander and Begrow, Frank and Schneider, Michael D and Garbers, David L and Kuhn, Michaela
Journal of Clinical Investigation, ISSN 0021-9738, 2003, Volume 111, Issue 9, pp. 1399 - 1407
  Cardiac hypertrophy is a common and often lethal complication of arterial hypertension. Atrial natriuretic peptide (ANP) has been postulated to exert local... 
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12. Full Text Heterozygous Mutations in Natriuretic Peptide Receptor-B (NPR2) Gene as a Cause of Short Stature in Patients Initially Classified as Idiopathic Short Stature
by Vasques, Gabriela A and Amano, Naoko and Docko, Ana J and Funari, Mariana F. A and Quedas, Elisangela P. S and Nishi, Mirian Y and Arnhold, Ivo J. P and Hasegawa, Tomonobu and Jorge, Alexander A. L
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 10/2013, Volume 98, Issue 10, pp. E1636 - E1644
Context: Based on the stature observed in relatives of patients with acromesomelic dysplasia, type Maroteaux, homozygous for mutations in natriuretic peptide... 
VELOCITY | ACROMESOMELIC DYSPLASIA | SECRETAGOGUE RECEPTOR | ENDOCRINOLOGY & METABOLISM | FIBROBLAST-GROWTH-FACTOR | BIRTH | DWARFISM | SHORT CHILDREN | FAMILY | Dwarfism - genetics | Humans | Receptors, Atrial Natriuretic Factor - genetics | Female | Heterozygote | Male | Mutation | Child | Body Height - genetics
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13. Full Text Association of Atrial Natriuretic Peptide and Type A Natriuretic Peptide Receptor Gene Polymorphisms With Left Ventricular Mass in Human Essential Hypertension
by Rubattu, Speranza and Bigatti, Giada and Evangelista, Anna and Lanzani, Chiara and Stanzione, Rosita and Zagato, Laura and Manunta, Paolo and Marchitti, Simona and Venturelli, Vanessa and Bianchi, Giuseppe and Volpe, Massimo and Stella, Paola
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2006, Volume 48, Issue 3, pp. 499 - 505
Association of Atrial Natriuretic Peptide and Type A Natriuretic Peptide Receptor Gene Polymorphisms With Left Ventricular Mass in Human Essential Hypertension... 
HEART | STROKE | RESPONSES | CARDIAC & CARDIOVASCULAR SYSTEMS | CYCLIC-GMP | DETERMINANTS | CARDIAC-HYPERTROPHY | 5'-FLANKING REGION | MICE | GUANYLYL CYCLASE-A | EXPRESSION | Humans | Male | Atrial Natriuretic Factor - blood | Guanine | Genetic Variation | Hypertension - blood | Hypertrophy, Left Ventricular - genetics | Atrial Natriuretic Factor - genetics | Ventricular Remodeling - genetics | Adult | Female | Cytosine | Hypertension - genetics | Promoter Regions, Genetic | Natriuretic Peptide, Brain - genetics | Echocardiography | Introns | Thymine | Adenine | Hypertension - physiopathology | Polymorphism, Genetic | Homozygote | Phenotype | Alleles | Receptors, Atrial Natriuretic Factor - genetics | Guanylate Cyclase - genetics | Heterozygote | Hypertension - diagnostic imaging | Hypertension | Genetic aspects | Peptides | Gene mutations | Genes | Societies | Associations, institutions, etc | Genetic polymorphisms | Natriuretic peptides | Variables | Body mass index | Rodents | Mortality | Cardiomyocytes | Abbreviations | Variance analysis | Patients | Age
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14. Full Text Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
by Kool, Marcel and Korshunov, Aney and Remke, Marc and Jones, David T. W and Schlanstein, Maria and Northcott, Paul A and Cho, Yoon-Jae and Koster, Jan and Schouten-van Meeteren, Antoinette and van Vuurden, Dannis and Clifford, Steven C and Pietsch, Torsten and von Bueren, Ane O and Rutkowski, Stefan and McCabe, Martin and Collins, V. Peter and Bäcklund, Magnus L and Haberler, Christine and Bourdeaut, Franck and Delattre, Olivier and Doz, Francois and Ellison, David W and Gilbertson, Richard J and Pomeroy, Scott L and Taylor, Michael D and Lichter, Peter and Pfister, Stefan M
Acta neuropathologica, ISSN 0001-6322, 2012, Volume 123, Issue 4, pp. 473 - 484
Medulloblastoma is the most common malignant brain tumor in childhood. Molecular studies from several groups around the world demonstrated that medulloblastoma... 
Pathology | Neurosciences | Medicine & Public Health | Medulloblastoma | Pediatric brain tumor | Subgroups | Meta-analysis | PROFILES | SUBTYPES | DISTINCT | PATHOLOGY | NEUROSCIENCES | ADULT | CLINICAL NEUROLOGY | PEDIATRIC MEDULLOBLASTOMAS | BETA-CATENIN STATUS | CHILDHOOD MEDULLOBLASTOMA | Multivariate Analysis | Meta-Analysis as Topic | Age Distribution | Kv1.1 Potassium Channel - metabolism | Cerebellar Neoplasms - diagnosis | Humans | Transcriptome | Child, Preschool | Hedgehog Proteins - metabolism | Male | Gene Expression Profiling | Wnt Proteins - metabolism | Young Adult | Chromosomes, Human, Pair 3 | Wnt Proteins - genetics | Hedgehog Proteins - genetics | Microarray Analysis | Adult | Female | Retrospective Studies | Cerebellar Neoplasms - classification | Medulloblastoma - genetics | Child | Gene Expression Regulation, Neoplastic - physiology | Kv1.1 Potassium Channel - genetics | Receptors, Atrial Natriuretic Factor - metabolism | Medulloblastoma - diagnosis | International Cooperation | Cerebellar Neoplasms - genetics | Chromosomes, Human, Pair 17 | Adolescent | Chromosome Aberrations | Survival Analysis | Cytogenetics | Receptors, Atrial Natriuretic Factor - genetics | Medulloblastoma - classification | Cohort Studies | Immunohistochemistry | Demography | Wnt protein | Brain tumors | Data processing | Single-nucleotide polymorphism | Gene expression | Survival | Reviews | Hedgehog protein | DNA | Children | Original Paper
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