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Structure, ISSN 0969-2126, 2010, Volume 18, Issue 10, pp. 1332 - 1341
Regulation of nuclear receptor (NR) activity is driven by alterations in the conformational dynamics of the receptor upon ligand binding. Previously, we... 
ENSEMBLE MODEL | MODULATORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | D 25-HYDROXYLASE | IDENTIFICATION | MASS-SPECTROMETRY | NUCLEAR RECEPTOR | HORMONE RECEPTORS | CELL BIOLOGY | BIOPHYSICS | DEUTERIUM-EXCHANGE | LIGAND | HYDROGEN-EXCHANGE | Luciferases - metabolism | Hydroxycholecalciferols - metabolism | Humans | Protein Multimerization | Transcriptional Activation - drug effects | Molecular Sequence Data | Crystallography, X-Ray | Hydrogen - chemistry | Luciferases - genetics | Calcitriol - analogs & derivatives | Transfection | Mass Spectrometry | HEK293 Cells | Calcitriol - metabolism | Retinoid X Receptors - metabolism | Hydrogen - metabolism | Binding, Competitive | Amino Acid Sequence | Deuterium - metabolism | Hydroxycholecalciferols - agonists | Deuterium - chemistry | Models, Molecular | Receptors, Calcitriol - chemistry | Calcitriol - chemistry | Retinoid X Receptors - chemistry | Receptors, Calcitriol - metabolism | Calcitriol - agonists | Deuterium Exchange Measurement - methods | Hydroxycholecalciferols - chemistry | Receptors, Calcitriol - agonists | Retinoid X Receptors - agonists | Calcitriol - pharmacology | Protein Conformation | Vitamin D - analogs & derivatives | Kinetics | Calcifediol | Alfacalcidol | Vitamin D | Structure | Crystals | Estrogen | Deuterium | Binding | Receptors | Dynamics | Ligands | Dimers | Vitamins | Crystal structure | Index Medicus
Journal Article
Journal Article
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 07/2017, Volume 171, pp. 75 - 79
Journal Article
Journal Article
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, ISSN 0960-0760, 07/2017, Volume 171, pp. 144 - 154
As a continuation of our efforts directed to the structure-activity relationship studies of vitamin D compounds, we present in this paper the synthesis of new... 
Secosteroids | D-seco vitamin D | MECHANISM | Vitamin D receptor | BIOCHEMISTRY & MOLECULAR BIOLOGY | VITAMIN-D-RECEPTOR | Vitamin D analogues | NUCLEAR RECEPTOR | 19-Norvitamin D | LIGANDS | ENDOCRINOLOGY & METABOLISM | 1,25-DIHYDROXYVITAMIN-D | Cellular differentiation | Transcriptional activity | Vitamin D3 24-Hydroxylase - genetics | Stereoisomerism | Weaning | Humans | Molecular Conformation | Vitamin D Deficiency - drug therapy | Male | Structure-Activity Relationship | Calcitriol - therapeutic use | Gastrointestinal Agents - chemistry | Receptors, Calcitriol - genetics | Calcitriol - analogs & derivatives | Drug Design | Vitamin D3 24-Hydroxylase - chemistry | Calcitriol - metabolism | Bone Density Conservation Agents - metabolism | Binding Sites | Vitamin D3 24-Hydroxylase - metabolism | Bone Density Conservation Agents - chemistry | Recombinant Proteins - metabolism | Bone Density Conservation Agents - therapeutic use | Models, Molecular | Recombinant Proteins - chemistry | Calcitriol - chemistry | Receptors, Calcitriol - metabolism | Rats, Sprague-Dawley | Bone Density Conservation Agents - pharmacology | Gastrointestinal Agents - pharmacology | Animals | Cell Differentiation - drug effects | Receptors, Calcitriol - agonists | Calcitriol - pharmacology | Gastrointestinal Agents - therapeutic use | HL-60 Cells | Genes, Reporter - drug effects | Ligands | Molecular Docking Simulation | Gastrointestinal Agents - metabolism
Journal Article
Biochemistry, ISSN 0006-2960, 12/2011, Volume 50, Issue 51, pp. 11025 - 11033
Journal Article
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 05/2011, Volume 18, Issue 5, pp. 556 - 563
Journal Article
Journal Article