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Journal Article
The Journal of Immunology, ISSN 0022-1767, 08/2007, Volume 179, Issue 3, pp. 1634 - 1647
1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) can modulate immune responses, but whether it directly affects B cell function is unknown. Patients with systemic... 
Immunologic Factors - deficiency | Apoptosis - drug effects | Humans | Middle Aged | Calcitriol - physiology | Apoptosis - genetics | Male | Receptors, Calcitriol - genetics | Plasma Cells - pathology | Receptors, Calcitriol - biosynthesis | Plasma Cells - drug effects | Cell Differentiation - genetics | Calcitriol - deficiency | Lupus Erythematosus, Systemic - drug therapy | Lupus Erythematosus, Systemic - immunology | Adult | Female | Growth Inhibitors - genetics | Steroid Hydroxylases - genetics | B-Lymphocytes - cytology | B-Lymphocytes - enzymology | Immunologic Factors - physiology | Cells, Cultured | Vitamin D3 24-Hydroxylase | Down-Regulation - drug effects | Down-Regulation - genetics | Vitamin D - blood | Gene Expression Regulation - drug effects | B-Lymphocytes - drug effects | Cell Differentiation - immunology | Apoptosis - immunology | B-Lymphocytes - immunology | Vitamin D - antagonists & inhibitors | Cell Differentiation - drug effects | Down-Regulation - immunology | Lymphocyte Activation - drug effects | ADP-ribosyl Cyclase 1 - biosynthesis | Calcitriol - pharmacology | Adolescent | Growth Inhibitors - physiology | Vitamin D - analogs & derivatives | Aged | Lupus Erythematosus, Systemic - pathology | Steroid Hydroxylases - biosynthesis | Immunologic Factors - pharmacology | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2006, Volume 103, Issue 31, pp. 11736 - 11741
We have demonstrated that cytokine thymic stromal lymphopoietin (TSLP), whose expression is rapidly induced upon keratinocyteselective ablation of retinoid X... 
T lymphocytes | Receptors | Ethanol | Vitamin D | Cytokines | Cholecalciferols | Keratinocytes | Skin | Mast cells | Inflammation | Retinoic acid receptor | Retinoid X receptor | Retinoic acid | Vitamin D receptor | retinoid X receptor | ALLERGIC INFLAMMATION | CELLS | MULTIDISCIPLINARY SCIENCES | skin | NUCLEAR RECEPTOR SUPERFAMILY | retinoic acid receptor | retinoic acid | GENE | ASTHMA | ABLATION | vitamin D receptor | 1,25-DIHYDROXYVITAMIN D-3 | MICE | ASSOCIATION | Skin - cytology | Retinoid X Receptor alpha - metabolism | Calcium - metabolism | Dermatologic Agents - administration & dosage | Humans | Calcitriol - adverse effects | Dermatologic Agents - adverse effects | Receptors, Calcitriol - genetics | Receptors, Retinoic Acid - genetics | Calcitriol - administration & dosage | Calcitriol - analogs & derivatives | Dermatitis, Atopic - chemically induced | Vitamins - immunology | Receptors, Retinoic Acid - agonists | Dermatitis, Atopic - immunology | Female | Cytokines - genetics | Dimerization | Skin - pathology | Cytokines - immunology | Retinoid X Receptor beta - metabolism | Vitamins - chemistry | Cells, Cultured | Retinoid X Receptor beta - genetics | Mice, Transgenic | Receptors, Retinoic Acid - metabolism | Keratinocytes - cytology | Receptors, Calcitriol - metabolism | Keratinocytes - immunology | Mice, Knockout | Retinoid X Receptor alpha - agonists | Vitamins - adverse effects | Animals | Retinoid X Receptor alpha - genetics | Mice | Dermatologic Agents - immunology | Administration, Topical | Retinoids - immunology | Skin - drug effects | Vitamins - administration & dosage | Calcitriol - immunology | Retinoid X Receptor beta - agonists | Physiological aspects | Causes of | Vitamin D3 | Atopic dermatitis | Tretinoin | Lymphocyte receptors | Genotype & phenotype | Molecular biology | Dermatitis | Index Medicus | Dermatitis, Atopic | Calcium | Calcitriol | Retinoid X Receptor alpha | Retinoids | Life Sciences | Retinoid X Receptor beta | Receptors, Retinoic Acid | Biochemistry, Molecular Biology | Vitamins | Dermatologic Agents | Receptors, Calcitriol | Biological Sciences
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2013, Volume 123, Issue 11, pp. 4579 - 4594
The TGF-beta superfamily comprises pleiotropic cytokines that regulate SMAD and non-SMAD signaling. TGF-beta-SMAD signal transd.uction is known to be involved... 
MEDICINE, RESEARCH & EXPERIMENTAL | GROWTH-FACTOR-BETA | TGF-BETA | UNILATERAL URETERAL OBSTRUCTION | RENIN-ANGIOTENSIN SYSTEM | INTERSTITIAL FIBROSIS | TUBULOINTERSTITIAL FIBROSIS | 1,25-DIHYDROXYVITAMIN D-3 | MICE LACKING SMAD3 | EXPERIMENTAL GLOMERULONEPHRITIS | NUCLEAR RECEPTOR | Kidney - pathology | Humans | Ureteral Obstruction - metabolism | RNA, Messenger - metabolism | Receptors, Calcitriol - genetics | Gene Knockdown Techniques | Calcitriol - analogs & derivatives | Kidney - metabolism | HEK293 Cells | Lactams - pharmacology | Ureteral Obstruction - genetics | Calcitriol - metabolism | Receptors, Calcitriol - antagonists & inhibitors | Promoter Regions, Genetic | Kidney - drug effects | Mice, Inbred C57BL | RNA, Messenger - genetics | Models, Molecular | Receptors, Calcitriol - metabolism | Drug Discovery | Animals | Signal Transduction - drug effects | Calcitriol - pharmacology | Ureteral Obstruction - pathology | Fibrosis | Ligands | Mice | Smad Proteins - metabolism | Transforming Growth Factor beta - metabolism | Care and treatment | Usage | Vitamin D | Physiological aspects | Calcifediol | Genetic aspects | Research | Alfacalcidol | Transforming growth factors | Health aspects | Kidneys | Gene expression | Experiments | Proteins | Studies | Signal transduction | Acids | Metabolites | Rodents | Collagen | Genetic engineering | Laboratory animals | Crystal structure | Index Medicus | Abridged Index Medicus
Journal Article
Science, ISSN 0036-8075, 3/2013, Volume 339, Issue 6126, pp. 1448 - 1453
Type I interferons (IFN-α and IFN-β) are important for protection against many viral infections, whereas type II interferon (IFN-γ) is essential for host... 
Monocytes | Messenger RNA | Tuberculosis | Mycobacterium tuberculosis | Antimicrobials | REPORTS | Leprosy | Infections | Skin | Lesions | Gene expression | LISTERIA-MONOCYTOGENES | ACTIVATION | PROFILES | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | HUMAN TUBERCULOSIS | IL-1-BETA | INDUCTION | DEPENDENT ANTIMICROBIAL PATHWAY | SARCOIDOSIS | LEPROSY | Up-Regulation | Interferon-beta - immunology | Humans | Transcriptome | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | Monocytes - metabolism | Monocytes - immunology | Interferon-gamma - metabolism | Antimicrobial Cationic Peptides - metabolism | RNA, Messenger - metabolism | Receptors, Calcitriol - genetics | Mycobacterium leprae - immunology | Interferon-beta - genetics | Interleukin-10 - metabolism | beta-Defensins - metabolism | Interferon-gamma - genetics | Antimicrobial Cationic Peptides - genetics | Leprosy, Lepromatous - genetics | Mycobacterium leprae - physiology | Leprosy, Tuberculoid - immunology | beta-Defensins - genetics | Leprosy, Lepromatous - immunology | RNA, Messenger - genetics | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Microbial Viability | Receptors, Calcitriol - metabolism | Leprosy, Tuberculoid - genetics | Tuberculosis - immunology | Leprosy, Lepromatous - metabolism | Interferon-beta - metabolism | Tuberculosis - genetics | Leprosy, Tuberculoid - metabolism | Interferon-gamma - immunology | Interleukin-10 - genetics | Interleukins | Physiological aspects | Host-parasite relationships | Anti-infective agents | Interferon | Genetic aspects | Health aspects | Antimicrobial agents | Pathogenesis | Index Medicus | Genes | Bacteria | Human behavior | Antiinfectives and antibacterials | Digital signatures
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2016, Volume 291, Issue 3, pp. 1514 - 1528
Muscle weakness and myopathy are observed in vitamin D deficiency and chronic renal failure, where concentrations of the active vitamin D3 metabolite,... 
Mitochondrial Dynamics | Phosphorylation | MicroRNAs - antagonists & inhibitors | Humans | Mitochondria, Muscle - metabolism | MicroRNAs - metabolism | Muscle, Skeletal - metabolism | Gene Expression Profiling | Green Fluorescent Proteins - genetics | Muscle, Skeletal - cytology | Receptors, Calcitriol - genetics | Recombinant Fusion Proteins - metabolism | Calcitriol - analogs & derivatives | RNA Interference | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Pyruvate Dehydrogenase (Lipoamide)-Phosphatase - metabolism | Calcitriol - metabolism | MicroRNAs - agonists | Protein-Serine-Threonine Kinases - metabolism | Receptors, Calcitriol - antagonists & inhibitors | Green Fluorescent Proteins - metabolism | Muscle, Skeletal - enzymology | Mitochondria, Muscle - enzymology | Signal Transduction | Cells, Cultured | Gene Expression Regulation | Oxidative Phosphorylation | Protein-Serine-Threonine Kinases - genetics | Receptors, Calcitriol - metabolism | GTP Phosphohydrolases - metabolism | GTP Phosphohydrolases - genetics | Receptors, Calcitriol - agonists | Protein Processing, Post-Translational | Pyruvate Dehydrogenase (Lipoamide)-Phosphatase - genetics | Index Medicus | Gene Regulation | 1,25-dihydroxyvitamin D3 | RNA-seq | WTSS | oxygen consumption | mitochondria | vitamin D | cell signaling | skeletal muscle | gene expression
Journal Article
Science, ISSN 0036-8075, 3/2006, Volume 311, Issue 5768, pp. 1770 - 1773
Journal Article
Reproduction, ISSN 1470-1626, 2017, Volume 154, Issue 6, pp. 735 - 744
We assessed the response of primary cultures of placental villous mononucleated trophoblasts and multinucleated syncytiotrophoblast to calcitriol, the most... 
IN-VITRO | REPRODUCTIVE BIOLOGY | 25-HYDROXYVITAMIN D-1-ALPHA-HYDROXYLASE | CHARCOAL TREATMENT | CULTURED HUMAN TROPHOBLASTS | PREECLAMPTIC PREGNANCIES | D DEFICIENCY | VITAMIN-D-RECEPTOR | PRETERM BIRTH | DEVELOPMENTAL BIOLOGY | HUMAN SYNCYTIOTROPHOBLASTS | HOUSEKEEPING GENES | Antigens, CD - immunology | Vitamin D3 24-Hydroxylase - genetics | Humans | Transcriptome | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | NF-kappa B - metabolism | Antigens, CD - genetics | Receptors, Calcitriol - genetics | Antigens, CD - metabolism | Lipopolysaccharide Receptors - metabolism | Trophoblasts - drug effects | Transfection | RNA Interference | Time Factors | Female | Calcitriol - metabolism | Low Density Lipoprotein Receptor-Related Protein-2 - genetics | Interleukin-8 - metabolism | Interleukin-6 - metabolism | Vitamin D3 24-Hydroxylase - metabolism | Trophoblasts - metabolism | Immunity, Innate - drug effects | Cells, Cultured | Gene Expression Regulation | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Receptors, Cell Surface - metabolism | Lipopolysaccharide Receptors - immunology | Low Density Lipoprotein Receptor-Related Protein-2 - metabolism | Receptors, Calcitriol - metabolism | Pregnancy | Trophoblasts - immunology | Calcitriol - pharmacology | Lipopolysaccharides - pharmacology | Lipopolysaccharide Receptors - genetics | Primary Cell Culture | Receptors, Cell Surface - genetics | Index Medicus
Journal Article
Hypertension, ISSN 0194-911X, 12/2014, Volume 64, Issue 6, pp. 1290 - 1298
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 01/2012, Volume 26, Issue 1, pp. 37 - 51
Journal Article