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The Journal of immunology (1950), ISSN 1550-6606, 2014, Volume 193, Issue 2, pp. 961 - 969
...) cell ligand a-galactosylceramide (alpha-GalCer) holds great promise in cancer therapy, although several concerns limit its use in clinics, including the uncontrolled response it promotes when delivered in a nonvectorized form... 
IMMUNITY | ACTIVATION | CANCER-PATIENTS | VIVO | KRN7000 | KILLER T-CELLS | CYTOKINE BIAS | ANTIGEN PRESENTATION | ANERGY | IMMUNOLOGY | TLR LIGANDS | Antigens, CD - immunology | Nanoparticles - chemistry | Minor Histocompatibility Antigens | Antibodies - chemistry | Dendritic Cells - immunology | Lectins, C-Type - immunology | Male | Galactosylceramides - administration & dosage | Neoplasms, Experimental - pathology | Lymphocyte Activation - immunology | T-Lymphocytes - metabolism | Natural Killer T-Cells - metabolism | Neoplasms, Experimental - immunology | Antibodies - immunology | CD8-Positive T-Lymphocytes - metabolism | Dendritic Cells - metabolism | T-Lymphocytes, Cytotoxic - immunology | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Mice, Transgenic | Receptors, Antigen, T-Cell, gamma-delta - immunology | Antigen Presentation - immunology | Galactosylceramides - chemistry | Receptors, Cell Surface - immunology | CD8 Antigens - immunology | Mice, Knockout | CD8 Antigens - metabolism | Animals | Galactosylceramides - immunology | T-Lymphocytes, Cytotoxic - metabolism | Cell Line, Tumor | T-Lymphocytes - immunology | Mice | Nanoparticles - administration & dosage | CD8-Positive T-Lymphocytes - immunology | Drug Delivery Systems - methods | Natural Killer T-Cells - immunology | Tumor Burden - immunology | Nanoparticles/administration & dosage | Receptors, Cell Surface/immunology | Neoplasms, Experimental/therapy | CD8 Antigens/metabolism | Dendritic Cells/metabolism | Innate immunity | Galactosylceramides/immunology | Antigen Presentation/immunology | Natural Killer T-Cells/metabolism | Receptors, Antigen, T-Cell, gamma-delta/metabolism | Life Sciences | Galactosylceramides/chemistry | Lectins, C-Type/immunology | CD8-Positive T-Lymphocytes/immunology | Antigens, CD/immunology | Immunology | Antibodies/chemistry | Antibodies/immunology | T-Lymphocytes, Cytotoxic/metabolism | T-Lymphocytes/metabolism | Drug Delivery Systems/methods | T-Lymphocytes/immunology | CD8-Positive T-Lymphocytes/metabolism | Galactosylceramides/administration & dosage | Natural Killer T-Cells/immunology | Receptors, Antigen, T-Cell, gamma-delta/immunology | CD8 Antigens/immunology | Tumor Burden/immunology | Neoplasms, Experimental/immunology | Lymphocyte Activation/immunology | Nanoparticles/chemistry | Dendritic Cells/immunology | T-Lymphocytes, Cytotoxic/immunology | Neoplasms, Experimental/pathology
Journal Article
Journal Article
The International journal of biological markers, ISSN 0393-6155, 1986
Journal
Cancer research (Chicago, Ill.), ISSN 0008-5472, 06/2010, Volume 70, Issue 11, pp. 4335 - 4345
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 02/2013, Volume 123, Issue 2, pp. 844 - 854
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 43, pp. 17253 - 17258
.... Specifically, the role of cell shape has not been explored, even though it has been observed that macrophages adopt different geometries in vivo... 
Phenotypes | Cell growth | Cytokines | Stem cells | Cell lines | Actins | Physiological regulation | Macrophages | Endothelial cells | Cells | FIBER | MATRIX | ACTIVATION | ACTIN | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DIFFERENTIATION | SCAFFOLDS | CULTURE | MESENCHYMAL STEM-CELLS | Mannose-Binding Lectins - metabolism | Arginase - metabolism | Lectins, C-Type - immunology | Cell Shape - immunology | Myosin-Light-Chain Kinase - antagonists & inhibitors | Cytochalasin D - pharmacology | Lectins, C-Type - metabolism | Arginase - immunology | Interleukin-4 - pharmacology | Flow Cytometry | Doxorubicin - analogs & derivatives | Inflammation Mediators - metabolism | Female | Immunophenotyping - methods | Cell Polarity - drug effects | Doxorubicin - metabolism | Macrophages - immunology | Cytokines - immunology | Amides - pharmacology | Biomarkers - metabolism | Inflammation Mediators - immunology | Cell Polarity - immunology | Cytokines - metabolism | Myosin-Light-Chain Kinase - metabolism | Mice, Inbred C57BL | Biomarkers - analysis | Cells, Cultured | Receptors, Cell Surface - metabolism | Macrophages - cytology | Interleukin-13 - pharmacology | Receptors, Cell Surface - immunology | Azepines - pharmacology | Cell Shape - drug effects | Macrophages - metabolism | Animals | Mannose-Binding Lectins - immunology | Lipopolysaccharides - pharmacology | Mice | Pyridines - pharmacology | Doxorubicin - immunology | Interferon-gamma - pharmacology | Microscopy, Fluorescence | Physiological aspects | Microbial genetics | Phenotype | Genetic aspects | Research | Biological Sciences | Physical Sciences
Journal Article
European journal of immunology, ISSN 0014-2980, 04/2016, Volume 46, Issue 4, pp. 929 - 940
.... In addition, we unexpectedly found increased surface expression of HLA‐E in human and Qa‐1 in mouse tumor cells exposed to combined oxygen and glucose deprivation. The induced Qa... 
MHC class I | Antigen presentation | Qa‐1 | Microenvironmental stress | Glucose deprivation hypoxia | HLA‐E | Qa-1 | HLA-E | HLA CLASS-I | PROTEIN | CD94/NKG2A | IMMUNOLOGY | HYPOXIA | CANCER | PEPTIDE | MHC CLASS-I | METABOLISM | GLUCOSE | CHAIN-RELATED MOLECULE | Cell Hypoxia - physiology | Humans | Mice, Inbred C57BL | Histocompatibility Antigens Class I - immunology | Histocompatibility Antigens Class I - genetics | Antigen Presentation - immunology | Mice, Knockout | NK Cell Lectin-Like Receptor Subfamily D - immunology | Tumor Microenvironment - immunology | Glucose - deficiency | NK Cell Lectin-Like Receptor Subfamily C - immunology | Animals | Neoplasms - immunology | Cell Line, Tumor | Killer Cells, Natural - immunology | Histocompatibility Antigens Class I - biosynthesis | Mice | CD8-Positive T-Lymphocytes - immunology | Stress, Physiological - immunology | Tumor Escape - immunology | Histocompatibility antigens | Glucose | T cells | Analysis | Dextrose | HLA histocompatibility antigens | Stresses | Antigens | Deprivation | Peptides | Tumor cells | CD8 antigen | Antigen processing | Lymphocytes T | T cell receptors | Exposure | Cell recognition | Major histocompatibility complex | Lymphocytes | Hypoxia | Histocompatibility antigen HLA | Solid tumors | Recognition | Tumors
Journal Article
Cancer immunology, immunotherapy, ISSN 1432-0851, 2005, Volume 55, Issue 7, pp. 808 - 818
...). TMV showed the presence of several surface determinants of tumour cells, e.g. HLA class I, CD29, CD44v7/8, CD51, chemokine receptors (CCR6, CX3CR1... 
Monocytes | Biomedicine | Immunology | Transfer | Oncology | Cancer Research | mRNA | CCR6 | Tumour-derived microvesicles | CANCER-CELLS | SURVIVAL | monocytes | APOPTOSIS | ACTIVATION | PHAGOCYTOSIS | ADHESION MOLECULES | IMMUNOLOGY | transfer | PLATELET MICROPARTICLES | PLASMA | ONCOLOGY | MEMBRANE-VESICLES | ENDOTHELIAL MICROPARTICLES | tumour-derived microvesicles | RNA, Messenger - immunology | Adenocarcinoma - ultrastructure | Tetradecanoylphorbol Acetate - pharmacology | Humans | Neoplasm Proteins - immunology | RNA, Messenger - analysis | Cell Line, Tumor - drug effects | Gene Expression Profiling | Monocytes - immunology | Membrane Proteins - analysis | Basigin - genetics | Basigin - immunology | Antigens, Neoplasm - analysis | Neoplasm Proteins - genetics | Receptors, Chemokine | Receptors, Cytokine - genetics | Antigens, Neoplasm - immunology | Cell Survival | Adenocarcinoma - immunology | RNA, Messenger - genetics | HLA Antigens - immunology | Pancreatic Neoplasms - ultrastructure | Immunophenotyping | Membrane Proteins - immunology | Cell Membrane - ultrastructure | Neoplasms - ultrastructure | Chemotaxis | Hyaluronan Receptors - genetics | Particle Size | Cell Line, Tumor - ultrastructure | Lung Neoplasms - immunology | Colorectal Neoplasms - immunology | Neoplasms - immunology | Cell Line, Tumor - immunology | Pancreatic Neoplasms - immunology | Colorectal Neoplasms - ultrastructure | Lung Neoplasms - ultrastructure | Neoplasm Proteins - analysis | Receptors, Cytokine - immunology | Cell Membrane - immunology | Genes, MHC Class I | Hyaluronan Receptors - immunology | Apoptosis | Growth factors | Messenger RNA | Tumors
Journal Article
PloS one, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e78508
CD4(+) T cells are essential to pathogenesis of ocular surface disease in dry eye... 
MIGRATION | RESPONSES | CYTOKINES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISTINCT | SUBSETS | PREVALENCE | EXPRESSION | LINEAGE | TH17 CELLS | Receptors, CCR6 - immunology | Th1 Cells - pathology | Matrix Metalloproteinases - genetics | Lymph Nodes - pathology | Cornea - immunology | Interleukin-17 - immunology | Adoptive Transfer | Th1 Cells - immunology | Xerophthalmia - genetics | Goblet Cells - immunology | Conjunctiva - pathology | Matrix Metalloproteinases - immunology | Scopolamine Hydrobromide | Female | Cornea - pathology | Interferon-gamma - genetics | Receptors, CXCR3 - deficiency | Disease Models, Animal | Th17 Cells - pathology | Xerophthalmia - pathology | Conjunctiva - immunology | Interleukin-17 - genetics | Epithelial Cells - pathology | Receptors, CCR6 - deficiency | Lymph Nodes - immunology | Mice, Knockout | Animals | Epithelial Cells - immunology | Interferon-gamma - immunology | Receptors, CXCR3 - genetics | Receptors, CCR6 - genetics | Receptors, CXCR3 - immunology | Th17 Cells - immunology | Mice | Goblet Cells - pathology | Xerophthalmia - chemically induced | Xerophthalmia - immunology | Cell Movement | Animal models | Cornea | Pathogenesis | Epithelial cells | Helper cells | Lymphocytes T | Matrix metalloproteinase | Cell surface | Lymph nodes | Eye | Receptors | Lymphocytes | Rodents | Animal tissues | Metalloproteinase | Localization | Immune system | Lymphatic system | Immune response | Psoriasis | Cytokines | Desiccants | Therapeutic applications | Inflammation | T cell receptors | CXCR3 protein | Conjunctiva | Chemokine receptors | CCR6 protein | Crohns disease | CD4 antigen | Medicine | γ-Interferon | Ligands | Eye diseases | Infiltration | Cell migration | Chemokines
Journal Article
PloS one, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e24776
.... First, we determined the cytokine pattern induced by 21 Bifidobacterium strains in peripheral blood mononuclear cells (PBMCs... 
CYTOKINES | HUMAN DENDRITIC CELLS | T(H)17 CELLS | MULTIDISCIPLINARY SCIENCES | LACTIC-ACID BACTERIA | IN-VIVO | REGULATORY T-CELLS | PROINFLAMMATORY IL-17(+) | INDUCTION | SURFACE-MARKERS | INTESTINAL BACTERIA | Bifidobacterium - immunology | Tumor Necrosis Factor-alpha - metabolism | Leukocytes, Mononuclear - metabolism | T-Lymphocytes, Regulatory - metabolism | Species Specificity | Dendritic Cells - immunology | Humans | Interleukin-17 - immunology | Monocytes - metabolism | Monocytes - immunology | Th2 Cells - immunology | Interferon-gamma - metabolism | Th1 Cells - immunology | Host-Pathogen Interactions - immunology | T-Lymphocytes, Regulatory - immunology | Th2 Cells - microbiology | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Flow Cytometry | Th17 Cells - metabolism | Leukocytes, Mononuclear - immunology | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Bifidobacterium - physiology | Dendritic Cells - metabolism | Leukocytes, Mononuclear - microbiology | Cytokines - immunology | Monocytes - microbiology | T-Lymphocytes, Regulatory - microbiology | CD4-Positive T-Lymphocytes - microbiology | Cytokines - metabolism | Bifidobacterium - classification | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Th2 Cells - metabolism | Interleukin-17 - metabolism | Th1 Cells - microbiology | Interferon-gamma - immunology | Dendritic Cells - microbiology | Th17 Cells - immunology | Interleukin-10 - immunology | Th17 Cells - microbiology | Bacteria | Dendritic cells | T cells | Tumor necrosis factor | Analysis | Dairy products | Genomics | Mucosa | Helper cells | Leukocytes (mononuclear) | Biochemistry | Lymphocytes T | Inductors | Cell activation | Microorganisms | Immunology | Lymphocytes | Plasticity | Peripheral blood mononuclear cells | Strains (organisms) | Immune system | Antigens | Automation | Immune response | Cytokines | Interleukin 12 | T cell receptors | Tumor necrosis factor-α | Metabolism | Immunological tolerance | Interleukin 17 | CD4 antigen | Inflammatory bowel disease | Probiotics | γ-Interferon | Interleukin 10 | Proteomics | Plastic properties | Differentiation
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2010, Volume 107, Issue 43, pp. 18587 - 18592
Surface Ig (sIg) of follicular lymphoma (FL) is vital for tumor cell survival. We found previously that the Ig in FL is unusual, because the variable region genes carry sequence motifs for N-glycan addition... 
Molecules | Receptors | Polysaccharides | Dendritic cells | B lymphocytes | Lectins | Follicular lymphoma | Macrophages | Blood | Tumors | B cell | Immunoglobulin | B-cell receptor | B-cell lymphoma | SURVIVAL | immunoglobulin | IMMUNOGLOBULIN VARIABLE REGION | MULTIDISCIPLINARY SCIENCES | B-CELLS | C-TYPE LECTINS | MANNOSE RECEPTOR | GENE | DC-SIGN | CARBOHYDRATE-RECOGNITION | IN-VIVO | TUMOR-ASSOCIATED MACROPHAGES | Cell Adhesion Molecules - genetics | Mannose-Binding Lectin - immunology | Humans | Cell Adhesion Molecules - antagonists & inhibitors | Lectins, C-Type - immunology | Cell Adhesion Molecules - immunology | Receptors, Antigen, B-Cell - metabolism | Lectins, C-Type - genetics | Receptors, Cell Surface - antagonists & inhibitors | Immunoglobulin M - chemistry | Gene Knockdown Techniques | Immunoglobulin M - metabolism | Signal Transduction - immunology | Single-Chain Antibodies - metabolism | Lymphoma, Follicular - genetics | Receptors, Antigen, B-Cell - chemistry | Lymphoma, Follicular - etiology | Mannose - chemistry | Somatic Hypermutation, Immunoglobulin | Lectins - immunology | Glycosylation | Immunity, Innate | Receptors, Cell Surface - immunology | Models, Immunological | B-Lymphocytes - immunology | Mannose-Binding Lectins - immunology | Lymphoma, Follicular - immunology | Receptors, Antigen, B-Cell - genetics | In Vitro Techniques | Lectins, C-Type - antagonists & inhibitors | Single-Chain Antibodies - chemistry | Receptors, Cell Surface - genetics | Immunoglobulins | Development and progression | Lymphomas | Observations | Properties | Immunoglobulin M | Calcium (intracellular) | Cell survival | Tumor cells | Variable region | Intracellular signalling | Mannose | N-glycans | Lymphoma | Mannose receptors | DC-SIGN protein | double prime B-cell receptor | Lymphocytes B | Mannose-binding lectin | Mutation | Probes | Immune system | Biological Sciences
Journal Article