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Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 718 - 728
Mouse conventional dendritic cells (cDCs) can be classified into two functionally distinct lineages: the CD8 alpha(+) (CD103(+)) cDC1 lineage, and the CD11b(+)... 
CLASSICAL DENDRITIC CELLS | HOMEOSTASIS | LYMPHOID-TISSUE | HEMATOPOIETIC STEM-CELLS | MOUSE | DYNAMICS | RECEPTOR | TRANSCRIPTION-FACTOR | IMMUNOLOGY | COMMITTED PROGENITORS | EXPRESSION | Antigens, CD - immunology | Stem Cells - immunology | Oligonucleotide Array Sequence Analysis | Dendritic Cells - immunology | Antigens, Ly - genetics | Transcriptome - immunology | Stem Cells - metabolism | Antigens, CD - metabolism | Lectins - metabolism | Flow Cytometry | Single-Cell Analysis - methods | Bone Marrow Cells - immunology | Integrin alpha Chains - immunology | Antigens, Ly - metabolism | Cell Lineage - genetics | Dendritic Cells - metabolism | Microscopy, Electron, Scanning | CD11b Antigen - immunology | Lectins - immunology | Mice, Inbred C57BL | Cells, Cultured | Receptors, Cell Surface - metabolism | Mice, Transgenic | Integrin alpha Chains - metabolism | Transcriptome - genetics | Receptors, Cell Surface - immunology | CD8 Antigens - immunology | CD8 Antigens - metabolism | Animals | Antigens, Ly - immunology | Dendritic Cells - ultrastructure | Lectins - genetics | CD11b Antigen - metabolism | Bone Marrow Cells - metabolism | Cell Lineage - immunology | Cluster Analysis | Receptors, Cell Surface - genetics | Medical research | Immune response | Dendritic cells | Cell development (Biology) | Bone marrow | Medicine, Experimental | Genetic aspects | Research | Properties | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 43, pp. 17253 - 17258
Phenotypic polarization of macrophages is regulated by a milieu of cues in the local tissue microenvironment. Although much is known about how soluble factors... 
Phenotypes | Cell growth | Cytokines | Stem cells | Cell lines | Actins | Physiological regulation | Macrophages | Endothelial cells | Cells | FIBER | MATRIX | ACTIVATION | ACTIN | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DIFFERENTIATION | SCAFFOLDS | CULTURE | MESENCHYMAL STEM-CELLS | Mannose-Binding Lectins - metabolism | Arginase - metabolism | Lectins, C-Type - immunology | Cell Shape - immunology | Myosin-Light-Chain Kinase - antagonists & inhibitors | Cytochalasin D - pharmacology | Lectins, C-Type - metabolism | Arginase - immunology | Interleukin-4 - pharmacology | Flow Cytometry | Doxorubicin - analogs & derivatives | Inflammation Mediators - metabolism | Female | Immunophenotyping - methods | Cell Polarity - drug effects | Doxorubicin - metabolism | Macrophages - immunology | Cytokines - immunology | Amides - pharmacology | Biomarkers - metabolism | Inflammation Mediators - immunology | Cell Polarity - immunology | Cytokines - metabolism | Myosin-Light-Chain Kinase - metabolism | Mice, Inbred C57BL | Biomarkers - analysis | Cells, Cultured | Receptors, Cell Surface - metabolism | Macrophages - cytology | Interleukin-13 - pharmacology | Receptors, Cell Surface - immunology | Azepines - pharmacology | Cell Shape - drug effects | Macrophages - metabolism | Animals | Mannose-Binding Lectins - immunology | Lipopolysaccharides - pharmacology | Mice | Pyridines - pharmacology | Doxorubicin - immunology | Interferon-gamma - pharmacology | Microscopy, Fluorescence | Physiological aspects | Microbial genetics | Phenotype | Genetic aspects | Research | Geometry | Genotype & phenotype | Morphology | Index Medicus | Biological Sciences | Physical Sciences
Journal Article
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 17, pp. 8880 - 8896
Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family, which includes dengue, West Nile, yellow fever, and Japanese encephalitis viruses, that... 
HUMAN DENDRITIC CELLS | DENGUE-VIRUS | REPLICATION | VIROLOGY | AEDES-ALBOPICTUS | ENCEPHALITIS-VIRUS | IMMUNE-RESPONSES | WEST-NILE-VIRUS | HEPARAN-SULFATE | AUTOPHAGY | I INTERFERON | Keratinocytes - virology | Membrane Glycoproteins - metabolism | Dendritic Cells - immunology | Humans | Flaviviridae - physiology | Virus Internalization | Interferon-Induced Helicase, IFIH1 | Lectins, C-Type - metabolism | Phagosomes - immunology | RNA Interference | Vero Cells | Myxovirus Resistance Proteins - biosynthesis | DEAD Box Protein 58 | Toll-Like Receptor 3 - immunology | Receptor Protein-Tyrosine Kinases - metabolism | Toll-Like Receptor 3 - metabolism | Cell Adhesion Molecules - metabolism | RNA, Small Interfering | Receptors, Cell Surface - genetics | Cell Adhesion Molecules - genetics | Ubiquitins - biosynthesis | Interferon-beta - immunology | Receptors, Virus - metabolism | Cercopithecus aethiops | Receptors, Virus - genetics | Lectins, C-Type - genetics | Insect Vectors - virology | Autophagy - immunology | Aedes - virology | Flaviviridae - immunology | Toll-Like Receptor 7 - immunology | HEK293 Cells | Toll-Like Receptor 3 - genetics | DEAD-box RNA Helicases - metabolism | Dendritic Cells - virology | Skin - virology | Flaviviridae Infections - immunology | Skin - immunology | Fibroblasts - virology | Proto-Oncogene Proteins - metabolism | Cells, Cultured | Interferon-beta - biosynthesis | Receptors, Cell Surface - metabolism | Proto-Oncogene Proteins - genetics | Hepatitis A Virus Cellular Receptor 1 | Flaviviridae Infections - virology | Membrane Glycoproteins - genetics | DEAD-box RNA Helicases - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Virus Replication | Cytokines - biosynthesis | Index Medicus | Life Sciences | Microbiology and Parasitology | Virology
Journal Article
Nature Cell Biology, ISSN 1465-7392, 10/2009, Volume 11, Issue 10, pp. 1254 - 1260
Brassinosteroid (BR) regulates gene expression and plant development through a receptor kinase-mediated signal transduction pathway. Despite the identification... 
TYROSINE PHOSPHORYLATION | GSK3 | PROTEIN-KINASE | BRI1 | BZR1 | MECHANISMS | ARABIDOPSIS | PLASMA-MEMBRANE | PLANT-GROWTH | FAMILY | CELL BIOLOGY | Genes, Plant | Recombinant Fusion Proteins - metabolism | Phytosterols - pharmacology | Cell Nucleus - metabolism | Plant Proteins - chemistry | Plants, Genetically Modified | Gene Expression Regulation, Plant | Plant Proteins - metabolism | Phosphorylation - drug effects | Nuclear Proteins - genetics | Steroids, Heterocyclic - metabolism | Steroids, Heterocyclic - pharmacology | Amino Acid Sequence | Glycogen Synthase Kinase 3 - chemistry | Glutathione Transferase - metabolism | Receptors, Cell Surface - metabolism | Brassinosteroids | Nuclear Proteins - metabolism | Signal Transduction - genetics | Binding Sites - genetics | Recombinant Fusion Proteins - chemistry | Glycogen Synthase Kinase 3 - metabolism | Nuclear Proteins - chemistry | Subcellular Fractions - metabolism | Cholestanols - pharmacology | Plant Proteins - genetics | Cell Nucleus - genetics | Glycogen Synthase Kinase 3 - genetics | Phytosterols - metabolism | Protein Binding | Signal Transduction - physiology | Mutation | Plant Growth Regulators - pharmacology | Receptors, Cell Surface - genetics | Development | Physiological aspects | Genetic aspects | Cellular signal transduction | Plants | Research | DNA binding proteins | Gene expression | Index Medicus
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 299 - 305
For most types of cancers, the cell at the origin of tumour initiation is still unknown. Here, we used mouse genetics to identify cells at the origin of basal... 
POPULATION | STEM-CELLS | SONIC HEDGEHOG | EPIDERMIS | HAIR FOLLICLE BULGE | KERATINOCYTES | CANCER | EXPRESSION | HUMAN HOMOLOG | MOUSE SKIN | CELL BIOLOGY | Epithelial Cells - metabolism | Cadherins - metabolism | Receptors, G-Protein-Coupled - metabolism | Skin - metabolism | Cell Count | Ear, External - pathology | Integrin beta4 - metabolism | Tail - pathology | Hair Follicle - pathology | Hedgehog Proteins - genetics | Neoplastic Stem Cells - metabolism | Kruppel-Like Transcription Factors - metabolism | Smoothened Receptor | Neoplastic Stem Cells - pathology | Cell Differentiation | Patched Receptors | Skin - pathology | Keratin-10 - metabolism | Epidermis - metabolism | Epidermis - pathology | RNA, Untranslated | Bacterial Proteins - genetics | Receptors, Cell Surface - metabolism | Epithelial Cells - pathology | Genes, Reporter - genetics | Mice, Transgenic | Carcinoma, Basal Cell - pathology | Mice, Inbred Strains | Clone Cells - metabolism | Keratin-14 - genetics | Carcinoma, Basal Cell - metabolism | Keratin-15 - metabolism | Keratin-19 - genetics | Proteins - genetics | Cell Lineage | Animals | Clone Cells - pathology | Proteins - metabolism | Models, Biological | Hair Follicle - metabolism | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Mice | Receptors, G-Protein-Coupled - genetics | Integrases - genetics | Keratin-15 - genetics | Luminescent Proteins - metabolism | Basal cell carcinoma | Stem cells | Genetic aspects | Cellular signal transduction | Research | Health aspects | Risk factors | Index Medicus
Journal Article
Journal Article