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Journal Article
Biological Psychiatry, ISSN 0006-3223, 2009, Volume 66, Issue 7, pp. 681 - 685
Journal Article
Biological Psychiatry, ISSN 0006-3223, 12/2017, Volume 82, Issue 12, pp. 866 - 874
Medication and psychotherapy treatments for posttraumatic stress disorder (PTSD) provide insufficient benefit for many patients. Substantial preclinical and... 
Clinical trial | Child abuse | Pharmacogenetics | Adrenocorticotropic hormone | Dexamethasone | DEPRESSION | PLACEBO | NOREPINEPHRINE | ANXIETY | PSYCHIATRY | NEUROSCIENCES | MESSENGER-RNA LEVELS | PTSD | FEAR | HORMONE | LOCUS-COERULEUS | SYSTEMS | Genetic Predisposition to Disease | Receptors, Corticotropin-Releasing Hormone - metabolism | Double-Blind Method | Stress Disorders, Post-Traumatic - metabolism | Humans | Kaplan-Meier Estimate | Receptors, Corticotropin-Releasing Hormone - genetics | Adult Survivors of Child Abuse | Oxadiazoles - therapeutic use | Psychotropic Drugs - therapeutic use | Psychotropic Drugs - adverse effects | Oxadiazoles - adverse effects | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Stress Disorders, Post-Traumatic - drug therapy | Treatment Failure | Adult | Azabicyclo Compounds - therapeutic use | Female | Polymorphism, Single Nucleotide | Stress Disorders, Post-Traumatic - genetics | Azabicyclo Compounds - adverse effects | Corticotropin releasing hormone | Medical research | Corticosteroids | Post-traumatic stress disorder | Medicine, Experimental | ACTH | Psychiatric services | Genetic polymorphisms | Index Medicus | Depressive Disorders | Antiadrenergic Agents | Multiple Traumatic Events | Neuroendocrinology | Comorbidity | Followup Study | Americans | Survivors | Neuropeptides | Reexperiencing | Genetic Markers | Neuroendocrine Testing | PTSD (DSM-IV) | Child Abuse | Randomized Clinical Trial | Treatment Effectiveness | Biochemical Markers | Psychopharmacology | Arousal | Adults | Females | Negative Therapeutic Reaction | Combat Exposure | Avoidance
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 05/2017, Volume 22, Issue 5, pp. 733 - 744
Journal Article
Biological Psychiatry, ISSN 0006-3223, 01/2018, Volume 83, Issue 2, pp. 137 - 147
Journal Article
Biological Psychiatry, ISSN 0006-3223, 10/2017, Volume 82, Issue 7, pp. 500 - 510
Corticotropin-releasing factor (CRF) mediates anxiogenic responses by activating CRF type 1 (CRF ) receptors in limbic brain regions. Anxiety is further... 
Central amygdala (CeA) | Excitatory | Anxiety | Endocannabinoid | Glutamate | CRF1 | ENDOGENOUS CANNABINOIDS | CENTRAL NUCLEUS | PSYCHIATRY | ALCOHOL-PREFERRING RATS | ENDOCANNABINOID SYSTEM | CB1 CANNABINOID RECEPTOR | NEUROSCIENCES | GLUTAMATERGIC NEUROTRANSMISSION | ANXIETY-RELATED BEHAVIOR | DEPOLARIZATION-INDUCED SUPPRESSION | RECEPTOR SIGNAL-TRANSDUCTION | CENTRAL-NERVOUS-SYSTEM | Amygdala - drug effects | Receptors, Corticotropin-Releasing Hormone - metabolism | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Anxiety - drug therapy | Excitatory Postsynaptic Potentials - drug effects | Piperidines - pharmacology | Rats, Mutant Strains | Exploratory Behavior - drug effects | Cannabinoids - metabolism | Excitatory Postsynaptic Potentials - genetics | Disease Models, Animal | Amidohydrolases - metabolism | Gene Expression Regulation - genetics | Amygdala - metabolism | Enzyme Inhibitors - pharmacology | Neurotransmitter Agents - metabolism | Rats | Amidohydrolases - antagonists & inhibitors | Pyrimidines - pharmacology | Maze Learning - drug effects | Corticotropin-Releasing Hormone - metabolism | Anxiety - pathology | Gene Expression Regulation - drug effects | Patch-Clamp Techniques | Animals | Pyridines - pharmacology | Corticotropin releasing hormone | Enzymes | ACTH | Hydrolases | Genetic aspects | Fatty acids | Neurophysiology | Stress (Psychology) | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2017, Volume 214, Issue 7, pp. 1877 - 1888
Journal Article
Nature Neuroscience, ISSN 1097-6256, 10/2003, Volume 6, Issue 10, pp. 1100 - 1107
Corticotropin-releasing hormone (CRH) is centrally involved in coordinating responses to a variety of stress-associated stimuli. Recent clinical data implicate... 
REDUCED ANXIETY | NERVOUS-SYSTEM | MATERNAL-CARE | PARAVENTRICULAR NUCLEUS | ANTAGONIST R121919 | MESSENGER-RNA EXPRESSION | MICE DEFICIENT | ELEVATED PLUS-MAZE | CHRONIC INFUSION | NEUROSCIENCES | MINERALOCORTICOID RECEPTOR | Receptors, Mineralocorticoid - genetics | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Limbic System - metabolism | RNA, Messenger - metabolism | Receptors, Corticotropin-Releasing Hormone - deficiency | Adaptation, Physiological - genetics | Stress, Physiological - metabolism | Limbic System - physiopathology | Anxiety Disorders - metabolism | Neural Pathways - physiopathology | Prosencephalon - metabolism | Hypothalamo-Hypophyseal System - physiopathology | Prosencephalon - physiopathology | Pituitary-Adrenal System - physiopathology | Pituitary-Adrenal System - metabolism | Stress, Physiological - genetics | Behavior, Animal - physiology | Stress, Physiological - physiopathology | Mutation - genetics | Corticotropin-Releasing Hormone - metabolism | Hypothalamo-Hypophyseal System - metabolism | Mice, Knockout | Animals | Neural Pathways - metabolism | Anxiety Disorders - genetics | Mice | Anxiety Disorders - physiopathology | Psychological aspects | Hormone receptors | Human acts | Physiological aspects | Research | Diagnosis | Stress (Psychology) | Human behavior | Risk factors | Index Medicus
Journal Article