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Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 8/2011, Volume 119, Issue 8, pp. 1142 - 1148
Background: The large and increasing number of chemicals released into the environment demands more efficient and cost-effective approaches for assessing... 
Chemical hazards | Receptors | Genomics | Environmental health | Agonists | Ligands | Cytotoxicity | Libraries | Environmental agencies | Research | Nuclear receptors | Chemical genomics | qHTS | Assay performance | Tox21 | assay performance | TOXICITY | ANTAGONISM | IDENTIFICATION | ESTROGEN-RECEPTOR | nuclear receptors | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | EVOLUTION | DISEASE | ASSAYS | SUPERFAMILY | HEALTH | chemical genomics | cytotoxicity | Peroxisome Proliferator-Activated Receptors - agonists | Cell Line | Retinoid X Receptor alpha - metabolism | Peroxisome Proliferator-Activated Receptors - antagonists & inhibitors | Humans | Orphan Nuclear Receptors - agonists | Receptors, Androgen - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Orphan Nuclear Receptors - metabolism | PPAR gamma - metabolism | Receptors, Thrombin - antagonists & inhibitors | Retinoid X Receptor alpha - agonists | Fragile X Mental Retardation Protein | Orphan Nuclear Receptors - antagonists & inhibitors | Retinoid X Receptor alpha - antagonists & inhibitors | PPAR gamma - antagonists & inhibitors | Receptors, Thrombin - agonists | Liver X Receptors | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Peroxisome Proliferator-Activated Receptors - metabolism | Receptors, Thrombin - metabolism | Estrogen Receptor alpha - metabolism | Environmental Pollutants - toxicity | Receptors, Cytoplasmic and Nuclear - metabolism | Environmental aspects | Physiological aspects | Cell receptors | Health aspects | Chemicals | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2013, Volume 145, Issue 3, pp. 574 - 582.e1
Journal Article
Nature Medicine, ISSN 1078-8956, 2015, Volume 21, Issue 2, pp. 159 - 165
Journal Article
Immunity, ISSN 1074-7613, 08/2009, Volume 31, Issue 2, pp. 245 - 258
Effective clearance of apoptotic cells by macrophages is essential for immune homeostasis. The transcriptional pathways that allow macrophages to sense and... 
MOLIMMUNO | CELLIMMUNO | SIGNALING PATHWAYS | IN-VITRO | PHAGOCYTOSIS | PHOSPHATIDYLSERINE RECEPTOR | LIPID-METABOLISM | MER TYROSINE KINASE | CHOLESTEROL EFFLUX | TAM RECEPTORS | IMMUNOLOGY | LIVER-X-RECEPTORS | MICE LACKING | Spleen - immunology | Receptor Protein-Tyrosine Kinases - immunology | Signal Transduction - immunology | Receptors, Cytoplasmic and Nuclear - immunology | DNA-Binding Proteins - agonists | Autoimmunity - immunology | Immune Tolerance - immunology | Liver X Receptors | c-Mer Tyrosine Kinase | Proto-Oncogene Proteins - immunology | Orphan Nuclear Receptors | Autoimmune Diseases - metabolism | Autoimmune Diseases - pathology | Macrophages - immunology | Proto-Oncogene Proteins - metabolism | DNA-Binding Proteins - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Autoimmune Diseases - immunology | Phagocytosis - immunology | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Spleen - cytology | Macrophages - cytology | DNA-Binding Proteins - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Mice, Knockout | Animals | Apoptosis - immunology | Spleen - metabolism | Mice | Tyrosine | Autoimmunity | Autoantibodies | Analysis | Development and progression | Macrophages | Apoptosis | Studies | Flow cytometry | Statistical analysis | Rodents | Software | Gene expression | Variance analysis | Cholesterol | Immune system | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2006, Volume 103, Issue 10, pp. 3920 - 3925
Obstruction of bile flow results in bacterial proliferation and mucosal injury in the small intestine that can lead to the translocation of bacteria across the... 
Edema | Receptors | Bile acids | Messenger RNA | RNA | Bacteria | Gene expression regulation | Epithelium | Ileum | Small intestine | Barrier | Biliary obstruction | Epithelial | ileum | FXR | OBSTRUCTIVE-JAUNDICE | bacteria | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | RENAL-FUNCTION | IDENTIFICATION | PROMOTES BACTERIAL TRANSLOCATION | epithelial barrier | RETICULOENDOTHELIAL FUNCTION | LIPID HOMEOSTASIS | EXPRESSION | biliary obstruction | Intestinal Mucosa - metabolism | Intestine, Small - pathology | Receptors, Cytoplasmic and Nuclear - deficiency | Humans | Transcription Factors - deficiency | Male | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | DNA-Binding Proteins - agonists | Steroid Hydroxylases - genetics | Intestine, Small - microbiology | Bile Acids and Salts - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Intestinal Mucosa - microbiology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Microscopy, Electron | Mice, Knockout | Gene Expression Regulation - drug effects | Isoxazoles - pharmacology | Transcription Factors - metabolism | Animals | Steroid Hydroxylases - deficiency | Cholestanetriol 26-Monooxygenase | Mice | Intestine, Small - metabolism | Transcription Factors - agonists | Intestinal Mucosa - pathology | Receptors, Cytoplasmic and Nuclear - metabolism | Research | Intestine, Small | Antibacterial agents | Bile acid metabolism | Pharmacology | Genes | Rodents | Bile | Index Medicus | Biological Sciences
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2007, Volume 28, Issue 1, pp. 91 - 106
Journal Article
Nature, ISSN 0028-0836, 01/2007, Volume 445, Issue 7124, pp. 219 - 223
The liver has a central role in glucose homeostasis, as it has the distinctive ability to produce and consume glucose. On feeding, glucose influx triggers gene... 
HOMEOSTASIS | METABOLISM | LIPOGENESIS | MULTIDISCIPLINARY SCIENCES | ELEMENT-BINDING PROTEIN-1C | LIVER | TRANSCRIPTION | ALPHA | X-RECEPTOR | MICE | DEFICIENCY | Transcription, Genetic - drug effects | Humans | DNA-Binding Proteins - metabolism | DNA-Binding Proteins - agonists | Liver - drug effects | Liver X Receptors | Receptors, Cytoplasmic and Nuclear - chemistry | Response Elements - genetics | Orphan Nuclear Receptors | Fatty Acids - metabolism | Retinoid X Receptors - genetics | Retinoid X Receptors - metabolism | Fasting | Gene Expression Regulation - genetics | Liver - metabolism | Glucose-6-Phosphate - pharmacology | Retinoid X Receptors - chemistry | Glucose - pharmacology | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Cholesterol - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Gene Expression Regulation - drug effects | Animals | Lipid Metabolism - drug effects | Benzoates - pharmacology | Cell Line, Tumor | Glucose - metabolism | Ligands | Mice | Transcription, Genetic - genetics | Benzylamines - pharmacology | Glucose-6-Phosphate - metabolism | Homeostasis - genetics | Fatty Acids - biosynthesis | Receptors, Cytoplasmic and Nuclear - metabolism | Medical research | Glucose | Gene expression | Insulin | Liver | Binding sites | Index Medicus
Journal Article