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Molecular cell, ISSN 1097-2765, 2010, Volume 40, Issue 1, pp. 63 - 74
.... The ATM-TRAF6-cIAP1 module stimulates TAB2-dependent TAK1 phosphorylation. Both nuclear PARP-1- and cytoplasmic ATM-driven signaling branches converge... 
MOLECULAR-MECHANISM | POLY(ADP-RIBOSYL)ATION | GENOTOXIC STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | DOUBLE-STRAND BREAKS | POLYUBIQUITIN CHAINS | ATM | BINDING | NEMO | PROTEIN-KINASES | CELL BIOLOGY | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Calcium - metabolism | Inhibitor of Apoptosis Proteins - genetics | Humans | Ubiquitin - metabolism | NF-kappa B - metabolism | DNA Breaks, Double-Stranded | Cell Nucleus - enzymology | DNA-Binding Proteins - metabolism | Cytosol - enzymology | Ubiquitination | Transfection | I-kappa B Kinase - metabolism | RNA Interference | Time Factors | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Inhibitor of Apoptosis Proteins - metabolism | TNF Receptor-Associated Factor 6 - genetics | Protein-Serine-Threonine Kinases - metabolism | Recombinant Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Signal Transduction | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | MAP Kinase Kinase Kinases - metabolism | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Hep G2 Cells | Protein Transport | Ubiquitin-Protein Ligases | Poly(ADP-ribose) Polymerases - metabolism | NF-kappa B - genetics | Ubiquitin-Conjugating Enzymes - metabolism | TNF Receptor-Associated Factor 6 - metabolism | Protein Binding | DNA Damage | HeLa Cells | Mutation | Poly (ADP-Ribose) Polymerase-1 | Adaptor Proteins, Signal Transducing - metabolism
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 485, Issue 7396, pp. 123 - 127
Journal Article
Oncogene, ISSN 0950-9232, 06/2016, Volume 35, Issue 26, pp. 3465 - 3475
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2012, Volume 287, Issue 36, pp. 30436 - 30443
An important feature of the adaptive immune response is its remarkable capacity to regulate the duration of inflammatory responses, and effector T cells have... 
SURVIVAL | INTERLEUKIN-27 | BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | P27(KIP1) | Cell Nucleus - immunology | Forkhead Transcription Factors - immunology | 14-3-3 Proteins - immunology | Humans | Cytoplasm - metabolism | CD4-Positive T-Lymphocytes - immunology | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Cell Nucleus - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Forkhead Transcription Factors - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Receptors, Antigen, T-Cell - immunology | Cytoplasm - genetics | Cytokines - genetics | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | 14-3-3 Proteins - genetics | Cytokines - immunology | Cyclin-Dependent Kinase Inhibitor p27 - immunology | Cytokines - metabolism | Receptors, Antigen, T-Cell - metabolism | Gene Expression Regulation - immunology | Jurkat Cells | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Forkhead Transcription Factors - genetics | Mice, Knockout | 14-3-3 Proteins - metabolism | Animals | Cell Nucleus - genetics | Cyclin-Dependent Kinase Inhibitor p21 - immunology | Cytoplasm - immunology | Active Transport, Cell Nucleus - immunology | Forkhead Box Protein O1 | Mice | Receptors, Antigen, T-Cell - genetics | STAT3 Transcription Factor - immunology | Forkhead Box Protein O3 | Lymphocyte Activation - physiology | Cyclin-Dependent Kinase Inhibitor p27 - genetics | FoxO | Immunology | T Cell | Interleukin | Cytokine | STAT3 | Cellular Immune Response
Journal Article
PLoS biology, ISSN 1545-7885, 2007, Volume 5, Issue 2, pp. e34 - 0189
The mammalian circadian timing system consists of a master pacemaker in neurons of the suprachiasmatic nucleus (SCN) and clocks of a similar molecular makeup... 
RAT-LIVER | REVEALS PERSISTENT | SUPRACHIASMATIC NUCLEUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEAT-SHOCK RESPONSE | MOUSE | BIOLOGY | GENE-EXPRESSION | TIME | PERIPHERAL-TISSUES | BINDING | INDIVIDUAL FIBROBLASTS | Male | Biological Clocks - drug effects | DNA-Binding Proteins - metabolism | Hepatocytes - cytology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Liver - drug effects | Cell Cycle Proteins - genetics | Nuclear Proteins - genetics | Hepatocytes - drug effects | Hepatocytes - physiology | Nuclear Receptor Subfamily 1, Group D, Member 1 | ARNTL Transcription Factors | Basic Helix-Loop-Helix Transcription Factors - genetics | Cell Cycle Proteins - metabolism | Circadian Rhythm - genetics | Mice, Transgenic | Nuclear Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Period Circadian Proteins | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Animals | Biological Clocks - genetics | Chronobiology Phenomena | Liver - physiology | Protein Array Analysis | Doxycycline - pharmacology | Anti-Bacterial Agents - pharmacology | Liver - cytology | Mice | Circadian Rhythm - drug effects | Receptors, Cytoplasmic and Nuclear - metabolism | Circadian rhythm | Kinases | Experiments | Liver | Binding sites | Neuroscience | Molecular Biology | Computational Biology | Genetics and Genomics | Mus (Mouse) | Biochemistry | Physiology | Mammals | Cell Biology
Journal Article
Journal Article
The Journal of cell biology, ISSN 1540-8140, 2009, Volume 185, Issue 7, pp. 1167 - 1180
.... Moreover, in the absence of hRio2, final cytoplasmic 40S maturation is blocked because the recycling of several trans-acting factors and cytoplasmic 18S-E precursor ribosomal RNA (rRNA [pre-rRNA... 
Yeasts | Transactivators | Cell nucleus | Cell lines | Stem cells | Ribosomes | HeLa cells | Protein precursors | Cytoplasm | Perceptual localization | YEAST | RIBONUCLEOPROTEIN COMPLEXES | PROTEIN | RNA | BIOGENESIS | PROTEOMIC CHARACTERIZATION | IN-VIVO | PRE-RIBOSOMES | NUCLEAR EXPORT RECEPTOR | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | RNA-Binding Proteins - genetics | ran GTP-Binding Protein - genetics | Humans | Molecular Sequence Data | Cytoplasm - metabolism | Recombinant Fusion Proteins - metabolism | RNA Interference | Trans-Activators - genetics | Cell Cycle Proteins - genetics | RNA Precursors - metabolism | Nuclear Proteins - genetics | Genes, Reporter | Protein-Serine-Threonine Kinases - metabolism | Ribosome Subunits, Small, Eukaryotic - genetics | Amino Acid Sequence | Protein Precursors - genetics | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | RNA Precursors - genetics | ran GTP-Binding Protein - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Protein Precursors - metabolism | Sequence Alignment | Animals | Karyopherins - metabolism | Karyopherins - genetics | Recombinant Fusion Proteins - genetics | Trans-Activators - metabolism | HeLa Cells | Ribosome Subunits, Small, Eukaryotic - metabolism | RNA-Binding Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Ribosomal RNA | Phosphotransferases | Life Sciences | Cellular Biology
Journal Article
The Journal of cell biology, ISSN 0021-9525, 4/2004, Volume 165, Issue 1, pp. 31 - 40
.... We have previously shown that the human decapping factors hDcp2 and hDcp1a are concentrated in specific cytoplasmic structures... 
RNA stability | Yeasts | Messenger RNA | HEK293 cells | RNA | Lymphocytes | Plasmids | Cell lines | Cells | Cytoplasm | FRET | Cell cycle | Green fluorescent protein | Transcriptional and translational inhibitors | cell cycle | DEAD BOX HELICASE | NUCLEAR-PROTEIN | green fluorescent protein | MAMMALIAN-CELLS | SACCHAROMYCES-CEREVISIAE | ENDONUCLEOLYTIC CLEAVAGE | CELL BIOLOGY | transcriptional and translational inhibitors | DECAPPING ENZYME | NONSENSE-MEDIATED DECAY | TERMINATION CODONS | SM-LIKE PROTEINS | Endoribonucleases - genetics | Humans | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Organelles - genetics | Organelles - ultrastructure | RNA Interference | Cytoplasmic Granules - metabolism | Membrane Proteins - metabolism | Protein Biosynthesis - genetics | Receptors, Chemokine - genetics | Proto-Oncogene Proteins - metabolism | Cell Line | DEAD-box RNA Helicases | Endoribonucleases - metabolism | Membrane Proteins - genetics | RNA, Messenger - genetics | Receptors, Chemokine - metabolism | Cell Compartmentation - genetics | Intracellular Signaling Peptides and Proteins | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | RNA Nucleotidyltransferases - metabolism | RNA Stability - genetics | Proteins - genetics | Proteins - metabolism | Cytoplasmic Granules - ultrastructure | RNA Nucleotidyltransferases - genetics | Cytoplasmic Granules - genetics | Protein Biosynthesis - drug effects | Receptors, CCR4 | Organelles - metabolism | Research | cell cycle; FRET; green fluorescent protein; transcriptional and translational inhibitors; RNA stability
Journal Article
Journal Article