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Chemical Communications, ISSN 1359-7345, 04/2011, Volume 47, Issue 13, pp. 3981 - 3982
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 09/2019, Volume 859, p. 172499
The leading causes of death in breast cancer patients are disease recurrence and metastasis. Growing evidence has suggested that metastasis possibly originates... 
l-Stepholidine | Breast cancer metastasis | Dopamine D1 receptor agonist | Cancer stem-like cell | Fenoldopam
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 07/2013, Volume 249, pp. 109 - 115
It is considered that functional deficiency of the NMDA receptors in the prefrontal cortex (PFC) is one of the causes of the cognitive impairment observed in... 
Spatial working memory | CANTAB | Schizophrenia | Marmoset | Ketamine | Dopamine receptor D1 | BATTERY | NEUROTRANSMISSION | COGNITION | NEUROSCIENCES | PREFRONTAL CORTEX | 1ST-EPISODE SCHIZOPHRENIA | MODELS | BEHAVIORAL SCIENCES | RECEPTORS | DEFICITS | MODULATION | METHYL-D-ASPARTATE | Phenols | Memory | Analysis
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 03/2013, Volume 24, Issue 5-6, pp. 278 - 284
A divergent and scalable asymmetric synthesis of the dopamine D1 agonists, A-86929, and dihydrexidine with high diastereo- and enantioselectivity was... 
EFFICACY | CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | SCHIZOPHRENIA | ALDEHYDES | D-1 RECEPTOR AGONIST | CHEMISTRY, INORGANIC & NUCLEAR | ABT-431 | POTENT | FULL AGONIST | DIACETYL PRODRUG | PARKINSONS-DISEASE | CONJUGATE ADDITION | Synthesis | Organic compounds
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 09/2010, Volume 18, Issue 18, pp. 6763 - 6770
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 2011, Volume 22, Issue 7, pp. 775 - 779
A concise asymmetric synthesis of first, high affinity domaine D1 full agonist, dihydrexidine has been accomplished via catalytic enantioselective... 
D-1 RECEPTOR | POTENT | PRODRUG | RECEPTOR AGONISTS | CHEMISTRY, PHYSICAL | DAR-0100 | A-86929 | CONJUGATE ADDITION
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2015, Volume 172, Issue 4, pp. 1124 - 1135
Rotigotine acts as a dopamine receptor agonist with high affinity for the dopamine D2, D3, D4 and D5 receptors but with a low affinity for the dopamine D1... 
Cell Line | Dopamine Agonists - pharmacology | Receptors, Dopamine - metabolism | Tetrahydronaphthalenes - pharmacology | Humans | Thiophenes - pharmacology | Radioligand Assay | Phenols | Dopamine receptors | Dopamine | Parkinsons disease | Research Papers
Journal Article
Journal Article
Brain Research, ISSN 0006-8993, 05/2019, Volume 1711, pp. 120 - 129
We investigated the mechanisms by which the dopamine D1 receptor alleviates morphine-exposure-induced cognitive impairments. Rats were intraperitoneally... 
Learning and memory | Dopamine D1 receptor | Morphine exposure | TLR4 | PAG | PKA | ACTIVATION | LONG-TERM-MEMORY | ACQUISITION | MORRIS WATER MAZE | NEUROSCIENCES | TRAUMATIC BRAIN-INJURY | TOLL-LIKE RECEPTORS | DEFICITS | EXPRESSION | CAMP | Immunohistochemistry | Dopamine | Memory | Analysis | Phenols | Morphine | Protein kinases
Journal Article
Journal Article
ACS medicinal chemistry letters, ISSN 1948-5875, 05/2019, Volume 10, Issue 5, pp. 792 - 799
Noncatechol heterocycles have recently been discovered as potent and selective G protein biased dopamine 1 receptor (D1R) agonists with superior... 
DRUG | dopamine 1 receptor | CHEMISTRY, MEDICINAL | LIGANDS | MEMORY | beta-arrestin | noncatechol | biased agonism | cAMP | functional selectivity | DISCOVERY
Journal Article
Journal Article