Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (20293) 20293
Book Chapter (357) 357
Newsletter (200) 200
Dissertation (52) 52
Book / eBook (14) 14
Reference (9) 9
Publication (5) 5
Transcript (5) 5
Conference Proceeding (4) 4
Government Document (4) 4
Newspaper Article (4) 4
Book Review (3) 3
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (13436) 13436
science & technology (13175) 13175
life sciences & biomedicine (12264) 12264
male (9153) 9153
neurosciences (7765) 7765
neurosciences & neurology (7318) 7318
rats (7152) 7152
biological and medical sciences (6687) 6687
humans (6377) 6377
dopamine (5966) 5966
medical sciences (4598) 4598
pharmacology & pharmacy (4465) 4465
female (3302) 3302
rats, sprague-dawley (3042) 3042
pharmacology. drug treatments (3038) 3038
mice (3019) 3019
psychiatry (2999) 2999
dopamine agonists - pharmacology (2755) 2755
dopamine receptors (2689) 2689
receptors, dopamine d2 - metabolism (2659) 2659
fundamental and applied biological sciences. psychology (2584) 2584
dose-response relationship, drug (2569) 2569
neuropharmacology (2533) 2533
dopamine - metabolism (2315) 2315
receptors (2109) 2109
neurology (1972) 1972
psychology. psychoanalysis. psychiatry (1961) 1961
schizophrenia (1912) 1912
dopamine antagonists - pharmacology (1898) 1898
rodents (1714) 1714
rats, wistar (1646) 1646
motor activity - drug effects (1635) 1635
receptors, dopamine d2 - agonists (1615) 1615
biochemistry & molecular biology (1545) 1545
brain (1440) 1440
corpus striatum - metabolism (1437) 1437
benzazepines - pharmacology (1416) 1416
psychopharmacology (1373) 1373
nervous system (1366) 1366
neurons (1355) 1355
receptors, dopamine - drug effects (1350) 1350
research (1339) 1339
dopamine d2 receptors (1330) 1330
adult (1320) 1320
vertebrates: nervous system and sense organs (1312) 1312
behavior, animal - drug effects (1308) 1308
parkinson's disease (1305) 1305
brain - metabolism (1279) 1279
phenols (1274) 1274
receptors, dopamine d2 - drug effects (1235) 1235
biomedicine (1233) 1233
proteins (1180) 1180
quinpirole (1175) 1175
central nervous system (1173) 1173
receptors, dopamine d2 - physiology (1169) 1169
receptor (1157) 1157
clinical neurology (1146) 1146
analysis (1129) 1129
receptors, dopamine - metabolism (1128) 1128
physiological aspects (1121) 1121
receptors, dopamine d1 - metabolism (1110) 1110
neurotransmitters. neurotransmission. receptors (1105) 1105
corpus striatum - drug effects (1104) 1104
dopamine d2 receptor antagonists (1098) 1098
signal transduction (1083) 1083
ligands (1058) 1058
dopamine agents - pharmacology (1033) 1033
mice, inbred c57bl (1033) 1033
receptors, dopamine d2 - genetics (1001) 1001
brain - drug effects (994) 994
serotonin (993) 993
disease models, animal (983) 983
antipsychotic agents - pharmacology (974) 974
neurons - drug effects (946) 946
middle aged (942) 942
pharmacology (939) 939
in vitro techniques (938) 938
pharmacology/toxicology (929) 929
neuroscience (924) 924
mental disorders (921) 921
dopamine - physiology (914) 914
catecholaminergic system (899) 899
science & technology - other topics (895) 895
multidisciplinary sciences (889) 889
striatum (882) 882
time factors (875) 875
neurons - metabolism (872) 872
rats, inbred strains (870) 870
receptors, dopamine - physiology (867) 867
neostriatum (862) 862
apomorphine - pharmacology (859) 859
nucleus accumbens (849) 849
2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1h-3-benzazepine - pharmacology (844) 844
cell biology (839) 839
dopamine - pharmacology (835) 835
research article (823) 823
receptors, dopamine d2 (815) 815
quinpirole - pharmacology (809) 809
cocaine (804) 804
gene expression (783) 783
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (20848) 20848
Japanese (85) 85
Russian (62) 62
French (39) 39
Chinese (19) 19
German (17) 17
Polish (10) 10
Portuguese (9) 9
Spanish (6) 6
Korean (4) 4
Breton (2) 2
Dutch (2) 2
Hungarian (2) 2
Bulgarian (1) 1
Italian (1) 1
Persian (1) 1
Turkish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Structure–Functional Selectivity Relationship Studies of β‑Arrestin-Biased Dopamine D2 Receptor Agonists
by Chen, Xin and Sassano, Maria F and Zheng, Lianyou and Setola, Vincent and Chen, Meng and Bai, Xu and Frye, Stephen V and Wetsel, William C and Roth, Bryan L and Jin, Jian
Journal of medicinal chemistry, ISSN 0022-2623, 08/2012, Volume 55, Issue 16, pp. 7141 - 7153
Cricetulus | Humans | Arrestins - genetics | Male | Piperazines - chemistry | Quinolones - pharmacology | Structure-Activity Relationship | Aripiprazole | Receptors, Dopamine D2 - metabolism | Arrestins - metabolism | Antipsychotic Agents - chemical synthesis | Hyperkinesis - drug therapy | Phencyclidine | Quinolones - chemistry | Quinolones - chemical synthesis | HEK293 Cells | Female | Hyperkinesis - chemically induced | Radioligand Assay | CHO Cells | Cricetinae | Receptors, Dopamine D2 - agonists | Piperazines - pharmacology | Mice, Knockout | Animals | Antipsychotic Agents - chemistry | Cyclic AMP - biosynthesis | beta-Arrestins | Ligands | Piperazines - chemical synthesis | Mice | Antipsychotic Agents - pharmacology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Functionally Selective Dopamine D2, D3 Receptor Partial Agonists
by Möller, Dorothee and Kling, Ralf C and Skultety, Marika and Leuner, Kristina and Hübner, Harald and Gmeiner, Peter
Journal of medicinal chemistry, ISSN 0022-2623, 06/2014, Volume 57, Issue 11, pp. 4861 - 4875
Cricetulus | Pyrazoles - chemical synthesis | Stereoisomerism | Humans | Piperazines - chemistry | Structure-Activity Relationship | Arrestins - metabolism | Antipsychotic Agents - chemical synthesis | Pyrazoles - chemistry | Swine | HEK293 Cells | Radioligand Assay | CHO Cells | Pyrazoles - pharmacology | Drug Partial Agonism | Receptors, Dopamine D2 - agonists | Heterocyclic Compounds, 2-Ring - chemistry | Oximes - chemical synthesis | Piperazines - pharmacology | Heterocyclic Compounds, 2-Ring - pharmacology | Oximes - chemistry | Receptors, Dopamine D3 - agonists | Animals | Antipsychotic Agents - chemistry | beta-Arrestin 2 | beta-Arrestins | Oximes - pharmacology | Piperazines - chemical synthesis | Mice | Molecular Docking Simulation | Antipsychotic Agents - pharmacology | GTP-Binding Protein alpha Subunits, Gi-Go - metabolism | Heterocyclic Compounds, 2-Ring - chemical synthesis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Brain region binding of the D2/3 agonist [11C]‐(+)‐PHNO and the D2/3 antagonist [11C]raclopride in healthy humans
by Graff‐Guerrero, Ariel and Willeit, Matthaeus and Ginovart, Nathalie and Mamo, David and Mizrahi, Romina and Rusjan, Pablo and Vitcu, Irina and Seeman, Philip and Wilson, Alan A and Kapur, Shitij
Human brain mapping, ISSN 1065-9471, 04/2008, Volume 29, Issue 4, pp. 400 - 410
substantia nigra | PET Scan | putamen | ventral striatum | caudate | positron emission tomography | dopamine | globus pallidus | HRRT | Caudate | Dopamine | Substantia nigra | Globus pallidus | Ventral striatum | Positron emission tomography | Putamen | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Radiodiagnosis. Nmr imagery. Nmr spectrometry | Investigative techniques, diagnostic techniques (general aspects) | Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation | Biological and medical sciences | Nervous system | Medical sciences | Raclopride - pharmacokinetics | Dopamine Antagonists - pharmacokinetics | Humans | Raclopride - metabolism | Male | Substantia Nigra - metabolism | Receptors, Dopamine D2 - metabolism | Corpus Striatum - metabolism | Globus Pallidus - diagnostic imaging | Tissue Distribution | Oxazines - pharmacokinetics | Globus Pallidus - metabolism | Oxazines - metabolism | Time Factors | Dopamine Antagonists - metabolism | Adult | Female | Neostriatum - metabolism | Dopamine Agonists - metabolism | Dopamine - metabolism | Binding, Competitive - physiology | Receptors, Dopamine D2 - agonists | Dopamine Agonists - pharmacokinetics | Brain Mapping - methods | Positron-Emission Tomography - methods | Binding, Competitive - drug effects | Substantia Nigra - diagnostic imaging | Neostriatum - diagnostic imaging | Corpus Striatum - diagnostic imaging | Dopamine D2 Receptor Antagonists | Carbon Radioisotopes | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text On the existence of a possible A2A-D2-β- arrestin2 complex: A2A agonist modulation of D2 agonist-induced β-arrestin2 recruitment
by Borroto-Escuela, Dasiel O and Romero-Fernandez, Wilber and Tarakanov, Alexander O and Ciruela, Francisco and Agnati, Luigi F and Fuxe, Kjell
Journal of molecular biology, ISSN 0022-2836, 03/2011, Volume 406, Issue 5, pp. 687 - 699
receptor-protein interaction | internalization | heteromerization | G-protein-coupled receptors | allosteric modulation | Cell Line | Humans | Protein Multimerization | Receptors, Dopamine D2 - agonists | Models, Molecular | Phenethylamines - metabolism | Adenosine A2 Receptor Agonists - metabolism | Receptor, Adenosine A2A - metabolism | Receptors, Dopamine D2 - metabolism | Arrestins - metabolism | beta-Arrestins | Adenosine - analogs & derivatives | Protein Structure, Quaternary | Adenosine - metabolism | Protein Binding | Index Medicus | Medicin och hälsovetenskap
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text New Dopamine D2 Receptor Agonist, [3H]MCL-536, for Detecting Dopamine D2high Receptors in Vivo
by Subburaju, Sivan and Sromek, Anna W and Seeman, Philip and Neumeyer, John L
ACS chemical neuroscience, ISSN 1948-7193, 06/2018, Volume 9, Issue 6, pp. 1283 - 1289
Dopamine D2high receptor | Parkinson's disease | schizophrenia | tritiated radioligand | aporphine | PET | Biochemistry & Molecular Biology | Neurosciences | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Neurosciences & Neurology | Chemistry, Medicinal | Science & Technology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor
by Free, R. Benjamin and Chun, Lani S and Moritz, Amy E and Miller, Brittney N and Doyle, Trevor B and Conroy, Jennie L and Padron, Adrian and Meade, Julie A and Xiao, Jingbo and Hu, Xin and Dulcey, Andrés E and Han, Yang and Duan, Lihua and Titus, Steve and Bryant-Genevier, Melanie and Barnaeva, Elena and Ferrer, Marc and Javitch, Jonathan A and Beuming, Thijs and Shi, Lei and Southall, Noel T and Marugan, Juan J and Sibley, David R
Molecular pharmacology, ISSN 0026-895X, 2014, Volume 86, Issue 1, pp. 96 - 105
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cell Line | Cricetulus | Humans | Structure-Activity Relationship | Receptors, Dopamine D2 - metabolism | Arrestins - metabolism | Arrestins - antagonists & inhibitors | Animals | Small Molecule Libraries | beta-Arrestins | HEK293 Cells | Signal Transduction - physiology | Cyclic AMP - metabolism | CHO Cells | GTP-Binding Proteins - metabolism | Protein Binding - physiology | Index Medicus | Accelerated Communication
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists
by Chen, Xin and McCorvy, John D and Fischer, Matthew G and Butler, Kyle V and Shen, Yudao and Roth, Bryan L and Jin, Jian
Journal of medicinal chemistry, ISSN 0022-2623, 12/2016, Volume 59, Issue 23, pp. 10601 - 10618
Dose-Response Relationship, Drug | Aripiprazole - pharmacology | Humans | Receptors, Dopamine D2 - agonists | HEK293 Cells | Aripiprazole - chemistry | Ligands | Aripiprazole - chemical synthesis | Molecular Structure | Structure-Activity Relationship | Drug Discovery | GTP-Binding Proteins - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Absorption, Biokinetics, and Metabolism of the Dopamine D2 Receptor Agonist Hordenine (N,N‑Dimethyltyramine) after Beer Consumption in Humans
by Sommer, Thomas and Göen, Thomas and Budnik, Nadja and Pischetsrieder, Monika
Journal of agricultural and food chemistry, ISSN 0021-8561, 02/2020, Volume 68, Issue 7, pp. 1998 - 2006
Beer - analysis | Tyramine - blood | Humans | Middle Aged | Dopamine Agonists - pharmacokinetics | Dopamine Agonists - urine | Male | Chromatography, High Pressure Liquid | Receptors, Dopamine D2 - metabolism | Tyramine - urine | Young Adult | Tandem Mass Spectrometry | Tyramine - pharmacokinetics | Receptors, Dopamine D2 - chemistry | Adult | Female | Tyramine - analogs & derivatives | Dopamine Agonists - blood | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text The role of ‘jackpot’ stimuli in maladaptive decision-making: dissociable effects of D1/D2 receptor agonists and antagonists
by Smith, Aaron P and Hofford, Rebecca S and Zentall, Thomas R and Beckmann, Joshua S
Psychopharmacology, ISSN 0033-3158, 5/2018, Volume 235, Issue 5, pp. 1427 - 1437
Decision-making | Discounting | Neurosciences | Gambling | Biomedicine | Dopamine | Suboptimal choice | Rat | Pharmacology/Toxicology | Psychiatry | Pharmacology & Pharmacy | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cues | Receptors, Dopamine D1 - antagonists & inhibitors | Dopamine Agonists - pharmacology | Choice Behavior - drug effects | Receptors, Dopamine D2 - agonists | Decision Making - drug effects | Dopamine - pharmacology | Rats | Male | Rats, Sprague-Dawley | Dose-Response Relationship, Drug | Animals | Dopamine Antagonists - pharmacology | Receptors, Dopamine D1 - physiology | Risk-Taking | Choice Behavior - physiology | Receptors, Dopamine D2 - physiology | Decision Making - physiology | Reward | Physiological aspects | Methods | Dopamine receptors | Signaling | Decision making | Blackout | Reinforcement | Pharmacology | Risk taking | Dopamine D2 receptors | Risk factors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Differential effects of D1 and D2 dopamine agonists on memory, motivation, learning and response time in non‐human primates
by Marino, Robert A and Levy, Ron
The European journal of neuroscience, ISSN 0953-816X, 01/2019, Volume 49, Issue 2, pp. 199 - 214
CANTAB | attention | learning | reaching | memory | dopamine | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Memory - drug effects | Learning - drug effects | Receptors, Dopamine D2 - agonists | Male | Macaca mulatta | Psychomotor Performance - drug effects | Psychomotor Performance - physiology | Motivation - drug effects | Neuropsychological Tests | Learning - physiology | Phenanthridines - administration & dosage | Animals | Motivation - physiology | Benzimidazoles - administration & dosage | Receptors, Dopamine D1 - physiology | Dopamine Agonists - administration & dosage | Receptors, Dopamine D1 - agonists | Receptors, Dopamine D2 - physiology | Memory - physiology | Dopamine | Memory | Mental task performance | Cognitive ability | Associative learning | Prefrontal cortex | Motor task performance | Reaction time task | Latency | Dopamine D1 receptors | Motivation | Cognition & reasoning | Reversal learning | Information processing | Neostriatum | Agonists | Receptor mechanisms | Short term memory | Dopamine D2 receptors | Dopamine receptors | Spatial memory | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Dopamine D2 receptor radiotracers [11 C](+)-PHNO and [3 H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo
by McCormick, Patrick N and Kapur, Shitij and Seeman, Philip and Wilson, Alan A
Nuclear medicine and biology, ISSN 0969-8051, 2008, Volume 35, Issue 1, pp. 11 - 17
Radiology | Rats | Dopamine D2 receptor | [ 11C](+)-PHNO | [ 3H]raclopride | Positron emission tomography | Brain biodistribution | H]raclopride | C](+)-PHNO | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Dopamine Agonists - pharmacology | Receptors, Dopamine D2 - agonists | Raclopride - metabolism | Male | Tritium | Receptors, Dopamine D2 - metabolism | Rats, Sprague-Dawley | Oxazines - metabolism | Animals | Dopamine Antagonists - pharmacology | Dopamine D2 Receptor Antagonists | Carbon Radioisotopes | Schizophrenia | Phenols | Radioactive tracers | Explosives | Dopamine | Tracers (Biology) | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Dopamine (D2/3) receptor agonist positron emission tomography radiotracer [11C]‐(+)‐PHNO is a D3 receptor preferring agonist in vivo
by Narendran, Rajesh and Slifstein, Mark and Guillin, Olivier and Hwang, Yuying and Hwang, Dah‐Ren and Scher, Erica and Reeder, Stephanie and Rabiner, Eugenii and Laruelle, Marc
Synapse (New York, N.Y.), ISSN 0887-4476, 12/2006, Volume 60, Issue 7, pp. 485 - 495
D2/3‐agonist | dopamine (DA) | amphetamine | [11C]PHNO | [11C]raclopride | antagonist | PET | Amphetamine | Dopamine (DA) | agonist | C]PHNO | Antagonist | C]raclopride | Brain - diagnostic imaging | Species Specificity | Receptors, Dopamine D3 - metabolism | Raclopride - metabolism | Receptors, Dopamine D3 - drug effects | Male | Piperazines - metabolism | Positron-Emission Tomography | Receptors, Dopamine D2 - metabolism | Globus Pallidus - diagnostic imaging | Brain - metabolism | Dose-Response Relationship, Drug | Globus Pallidus - metabolism | Oxazines - metabolism | Time Factors | Dopamine Antagonists - metabolism | Receptors, Dopamine D2 - drug effects | Female | Raclopride - pharmacology | Dopamine Agonists - metabolism | Oxazines - pharmacology | Dopamine Agonists - pharmacology | Binding, Competitive - physiology | Down-Regulation - drug effects | Papio anubis | Piperazines - pharmacology | Binding, Competitive - drug effects | Brain - drug effects | Down-Regulation - physiology | Globus Pallidus - drug effects | Animals | Dopamine Antagonists - pharmacology | Brain Mapping | Carbon Radioisotopes | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights