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Nature, ISSN 0028-0836, 03/2018, Volume 555, Issue 7695, pp. 269 - 273
Dopamine is a neurotransmitter that has been implicated in processes as diverse as reward, addiction, control of coordinated movement, metabolism and hormonal... 
LIGANDS | CLONING | CRYSTAL-STRUCTURE | PHARMACOLOGY | MULTIDISCIPLINARY SCIENCES | CHARGES | RHODOPSIN | MODEL | BETA-ADRENERGIC RECEPTOR | DISCOVERY | AGONIST | Receptors, Dopamine D4 - chemistry | Humans | Receptors, Dopamine D3 - chemistry | Receptors, Dopamine D3 - metabolism | Mutant Proteins - genetics | Models, Molecular | Crystallography, X-Ray | Mutant Proteins - metabolism | Risperidone - chemistry | Receptors, Dopamine D2 - metabolism | Receptors, Dopamine D2 - genetics | Antipsychotic Agents - chemistry | Mutant Proteins - chemistry | Drug Design | Hydrophobic and Hydrophilic Interactions | Receptors, Dopamine D2 - chemistry | Antipsychotic Agents - metabolism | Ligands | Receptors, Dopamine D4 - metabolism | Risperidone - metabolism | Kinetics | Mutation | Binding Sites | Pharmacology, Experimental | Drug interactions | Physiological aspects | Research | Risperidone | Structure | Dopamine receptors | Drugs | Attention deficit disorder | Neuroleptics | Parkinson's disease | Molecular structure | Mental disorders | Parkinsons disease | Schizophrenia | Mental depression | Proteins | Psychotropic drugs | Receptors | Vomiting | Reinforcement | Dopamine D2 receptors | Movement disorders | Crystal structure | Dopamine | Neurodegenerative diseases | Secretion | Attention deficit hyperactivity disorder | Nausea | Metabolism | Side effects | Addiction | Structure-function relationships
Journal Article
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2016, Volume 113, Issue 50, pp. E8178 - E8186
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 11/2015, Volume 20, Issue 11, pp. 1373 - 1385
Hetero-oligomers of G-protein-coupled receptors have become the subject of intense investigation, because their purported potential to manifest signaling and... 
RAT STRIATUM | PSYCHIATRY | BASAL GANGLIA | COMPARTMENTAL ORGANIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHOLIPASE-C | BAC TRANSGENIC MICE | NEUROSCIENCES | NUCLEUS-ACCUMBENS | GENE-EXPRESSION | MEDIUM SPINY NEURONS | PHOSPHOINOSITIDE HYDROLYSIS | ADENYLATE-CYCLASE | Humans | Nucleus Accumbens - metabolism | Motor Activity - drug effects | Male | Receptors, Dopamine D2 - metabolism | Corpus Striatum - metabolism | Receptors, Dopamine D1 - metabolism | Protein Multimerization - physiology | HEK293 Cells | Phosphorylation - drug effects | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Protein Structure, Tertiary | Dopamine Agonists - pharmacology | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Mice, Inbred C57BL | Grooming - drug effects | Models, Molecular | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - analogs & derivatives | Receptors, Dopamine D2 - genetics | Mice, Knockout | Motor Activity - genetics | Animals | Dopamine Antagonists - pharmacology | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology | Corpus Striatum - drug effects | Luminescent Proteins - genetics | Mice | Nucleus Accumbens - drug effects | Protein Multimerization - drug effects | Luminescent Proteins - metabolism | Receptors, Dopamine D1 - genetics | Oligomers | Depression, Mental | Schizophrenia | Physiological aspects | Research | Risk factors | Dopamine receptors | BRET | striatum | Gαq | hetero-oligomer | proximity ligation assay | biased agonism | dopamine
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Journal Article
Journal Article