X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (45723) 45723
Book Review (14189) 14189
Publication (5822) 5822
Book Chapter (492) 492
Book / eBook (318) 318
Conference Proceeding (148) 148
Dissertation (53) 53
Reference (16) 16
Magazine Article (8) 8
Newsletter (7) 7
Data Set (5) 5
Government Document (2) 2
Newspaper Article (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (40649) 40649
humans (27985) 27985
animals (26752) 26752
mice (11524) 11524
cell biology (8623) 8623
male (8420) 8420
female (7909) 7909
signal transduction (7648) 7648
expression (7168) 7168
biochemistry & molecular biology (6741) 6741
cells, cultured (6590) 6590
rats (6462) 6462
oncology (6123) 6123
cancer (5232) 5232
proteins (4930) 4930
research (4852) 4852
pharmacology & pharmacy (4698) 4698
inflammation (4529) 4529
gene expression (4510) 4510
receptor (4220) 4220
apoptosis (4158) 4158
physiological aspects (4063) 4063
article (4060) 4060
activation (3978) 3978
phosphorylation (3808) 3808
immunology (3724) 3724
signal transduction - drug effects (3723) 3723
neurosciences (3674) 3674
cell line, tumor (3644) 3644
cells (3643) 3643
analysis (3621) 3621
receptors (3601) 3601
gene-expression (3442) 3442
physiology (3396) 3396
rodents (3319) 3319
endocrinology & metabolism (3218) 3218
cell line (3208) 3208
health aspects (3134) 3134
angiogenesis (3066) 3066
research article (3038) 3038
cytokines (3030) 3030
multidisciplinary sciences (3001) 3001
kinases (2996) 2996
in-vitro (2828) 2828
cell proliferation (2729) 2729
medicine (2709) 2709
in-vivo (2563) 2563
mice, inbred c57bl (2516) 2516
medicine, research & experimental (2442) 2442
cell proliferation - drug effects (2381) 2381
proliferation (2376) 2376
signal transduction - physiology (2371) 2371
abridged index medicus (2362) 2362
care and treatment (2348) 2348
disease models, animal (2325) 2325
fibroblasts (2315) 2315
genetic aspects (2285) 2285
rats, sprague-dawley (2240) 2240
stem cells (2198) 2198
tumors (2198) 2198
ligands (2181) 2181
growth (2171) 2171
biology (2130) 2130
nf-kappa-b (2130) 2130
adult (2069) 2069
inhibition (2058) 2058
dose-response relationship, drug (2056) 2056
differentiation (2053) 2053
middle aged (2024) 2024
science (2010) 2010
review (1999) 1999
rna, messenger - metabolism (1993) 1993
development and progression (1966) 1966
immunohistochemistry (1964) 1964
growth factors (1910) 1910
fibrosis (1861) 1861
metastasis (1847) 1847
growth-factor (1832) 1832
mice, knockout (1829) 1829
enzyme inhibitors - pharmacology (1779) 1779
medicine & public health (1757) 1757
blotting, western (1717) 1717
antineoplastic agents - pharmacology (1688) 1688
breast cancer (1671) 1671
apoptosis - drug effects (1668) 1668
growth-factor receptor (1661) 1661
fibroblasts - metabolism (1655) 1655
reverse transcriptase polymerase chain reaction (1651) 1651
endothelial growth-factor (1636) 1636
up-regulation (1622) 1622
biochemistry (1599) 1599
mutation (1575) 1575
time factors (1573) 1573
gene expression regulation (1530) 1530
cell differentiation (1492) 1492
models, biological (1458) 1458
pathology (1450) 1450
aged (1447) 1447
biomedicine (1444) 1444
vascular endothelial growth factor (1435) 1435
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (236) 236
UofT at Mississauga - Stacks (13) 13
Online Resources - Online (11) 11
Collection Dvlpm't (Acquisitions) - Closed Orders (10) 10
UTL at Downsview - May be requested (8) 8
Collection Dvlpm't (Acquisitions) - Vendor file (6) 6
UofT at Scarborough - Stacks (6) 6
Chemistry (A D Allen) - Stacks (1) 1
Dentistry (Harry R Abbott) - Stacks (1) 1
Engineering & Comp. Sci. - Stacks (1) 1
Providence Healthcare - Reference (1) 1
Providence Healthcare - Stacks (1) 1
St. Michael's Hospital - Stacks (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
Toronto East General Hospital - Stacks (1) 1
Trinity College (John W Graham) - Storage (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (46212) 46212
Japanese (22) 22
German (21) 21
Spanish (21) 21
Chinese (20) 20
French (18) 18
Hungarian (4) 4
Korean (4) 4
Russian (3) 3
Italian (2) 2
Turkish (2) 2
Arabic (1) 1
Hebrew (1) 1
Polish (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 01/2005, Volume 25, Issue 1, pp. 71 - 76
OBJECTIVE—Low-molecular-weight heparin (LMWH) exerts antitumor activity in clinical trials. The K5 polysaccharide from Escherichia coli has the same structure... 
Angiogenesis | Integrin | Heparin | FGF | Endothelium | endothelium | PROTEOGLYCANS | angiogenesis | CANCER | heparin | CAPSULAR POLYSACCHARIDE | ALPHA(V)BETA | ANGIOGENESIS INHIBITORS | BIOLOGICAL-ACTIVITY | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | integrin | RECEPTORS | HEMATOLOGY | BINDING | Neovascularization, Physiologic - drug effects | Bacterial Capsules | Cricetulus | Heparin, Low-Molecular-Weight - genetics | Fibroblast Growth Factors - analogs & derivatives | Heparan Sulfate Proteoglycans - deficiency | Polysaccharides, Bacterial - biosynthesis | Integrin alphaVbeta3 - metabolism | Fibroblast Growth Factors - metabolism | Polysaccharides, Bacterial - genetics | CHO Cells - metabolism | Cattle | Chorioallantoic Membrane - drug effects | Fibroblast Growth Factor 2 - metabolism | CHO Cells - chemistry | Heparin, Low-Molecular-Weight - chemical synthesis | Endothelial Cells - chemistry | Genetic Engineering - methods | Cell Line | Angiogenesis Inhibitors - genetics | Cricetinae | Heparin, Low-Molecular-Weight - biosynthesis | Endothelial Cells - metabolism | Fibroblast Growth Factor 2 - analogs & derivatives | Escherichia coli - chemistry | Chick Embryo | Fibroblast Growth Factor 2 - antagonists & inhibitors | Animals | Angiogenesis Inhibitors - biosynthesis | Cell Adhesion - physiology | Escherichia coli - genetics | Heparan Sulfate Proteoglycans - metabolism | Cell Proliferation - drug effects | Mice | Heparan Sulfate Proteoglycans - analogs & derivatives | Index Medicus
Journal Article
Cancer Discovery, ISSN 2159-8274, 12/2012, Volume 2, Issue 12, pp. 1118 - 1133
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2013, Volume 19, Issue 13, pp. 3693 - 3702
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2011, Volume 54, Issue 20, pp. 7066 - 7083
Journal Article
Oncogene, ISSN 0950-9232, 06/2013, Volume 32, Issue 25, pp. 3059 - 3070
Fibroblast growth factor receptors (FGFRs) can act as driving oncoproteins in certain cancers, making them attractive drug targets. Here we have characterized... 
tyrosine kinase inhibitors | ERK1/2 | FGFR | PKB | acquired resistance | MULTIPLE-MYELOMA | BLADDER-CANCER | PHOSPHORYLATION | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | STOMACH-CANCER | LINES | CELL BIOLOGY | C/EBP-ALPHA | AMPLIFICATION | GENE | ONCOLOGY | GASTRIC-CANCER | GENETICS & HEREDITY | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Humans | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Receptor, Fibroblast Growth Factor, Type 3 - antagonists & inhibitors | Multiple Myeloma - drug therapy | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Receptor, Fibroblast Growth Factor, Type 2 - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Pyrazoles - pharmacology | Receptor, Fibroblast Growth Factor, Type 3 - genetics | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Pyrimidines - pharmacology | Stomach Neoplasms - drug therapy | Urinary Bladder Neoplasms - drug therapy | Receptor Protein-Tyrosine Kinases - drug effects | Breast Neoplasms - drug therapy | Piperazines - pharmacology | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | Signal Transduction - drug effects | Receptors, Fibroblast Growth Factor - metabolism | Cell Line, Tumor | Mutation | Multiple Myeloma - genetics | Gene mutations | Analysis | Physiological aspects | Genetic aspects | Fibroblast growth factors | Research | Health aspects | Fibroblast growth factor receptors | Proteins | Signal transduction | Inhibitor drugs | Gene expression | Cancer | Index Medicus
Journal Article
Hepatology, ISSN 0270-9139, 04/2014, Volume 59, Issue 4, pp. 1427 - 1434
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 04/2013, Volume 28, Issue 4, pp. 899 - 911
Fibroblast growth factor 23 (FGF23) is a circulating factor secreted by osteocytes that is essential for phosphate homeostasis. In kidney proximal tubular... 
TARGETED THERAPY | FIBROBLAST GROWTH FACTOR RECEPTOR | PHOSPHATE HOMEOSTASIS | HYPOPHOSPHATEMIC RICKETS | FGF23 | phosphate homeostasis | targeted therapy | hypophosphatemic rickets | fibroblast growth factor receptor | KLOTHO | VITAMIN-D METABOLISM | X-LINKED HYPOPHOSPHATEMIA | DMP1 | PATHOGENIC ROLE | HYP MICE | ENDOCRINOLOGY & METABOLISM | MINERAL METABOLISM | BONE | EXPRESSION | Growth Plate - pathology | Femur - pathology | Rickets, Hypophosphatemic - pathology | Extracellular Matrix Proteins - deficiency | Body Weight - drug effects | Vitamin D - biosynthesis | Fibroblast Growth Factors - metabolism | Kidney - metabolism | Growth Plate - drug effects | Rickets, Hypophosphatemic - metabolism | Homeostasis - drug effects | Minerals - metabolism | Extracellular Matrix Proteins - metabolism | Tail - anatomy & histology | Kidney - drug effects | Bone Development - drug effects | Mice, Inbred C57BL | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Phenylurea Compounds - therapeutic use | Femur - drug effects | Ions | Rickets, Hypophosphatemic - drug therapy | Pyrimidines - pharmacology | Animals | Signal Transduction - drug effects | Pyrimidines - therapeutic use | Receptors, Fibroblast Growth Factor - metabolism | Vitamin D - analogs & derivatives | Phenylurea Compounds - pharmacology | Phosphates | Rickets | Vitamin D | Heterocyclic compounds | Analysis | Calcifediol | Fibroblast growth factors | Alfacalcidol | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 01/2013, Volume 73, Issue 4, pp. 1298 - 1307
Fibroblast growth factor (FGF) receptor (FGFR) substrate 2 (FRS2) is an adaptor protein that plays a critical role in FGFR signaling. FRS2 is located on... 
DEDIFFERENTIATED LIPOSARCOMA | GENE | ONCOLOGY | COPY-NUMBER | GROWTH | MDM2 | CLASSIFICATION | PLEOMORPHIC SARCOMA | EXPRESSION | CANCER | CELL-LINE | Immunohistochemistry | Receptor, Fibroblast Growth Factor, Type 4 - metabolism | Proto-Oncogene Proteins c-mdm2 - genetics | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Receptor, Fibroblast Growth Factor, Type 3 - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | Receptor, Fibroblast Growth Factor, Type 3 - metabolism | Arginine - analogs & derivatives | Liposarcoma - metabolism | Neoplasm Grading | RNA Interference | Receptors, Fibroblast Growth Factor - genetics | Female | Receptor, Fibroblast Growth Factor, Type 2 - antagonists & inhibitors | Membrane Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Fibroblast Growth Factor, Type 4 - genetics | Proto-Oncogene Proteins c-mdm2 - metabolism | Receptor, Fibroblast Growth Factor, Type 3 - genetics | Signal Transduction | Membrane Proteins - genetics | Liposarcoma - pathology | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Liposarcoma - genetics | Pyrimidines - pharmacology | Cyclin-Dependent Kinase 4 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Gene Amplification | Receptors, Fibroblast Growth Factor - metabolism | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Phenylurea Compounds - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Receptor, Fibroblast Growth Factor, Type 4 - antagonists & inhibitors | Receptor, Fibroblast Growth Factor, Type 2 - genetics | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 06/2008, Volume 68, Issue 12, pp. 4774 - 4782
Inhibition of tumor angiogenesis through blockade of the vascular endothelial growth factor (VEGF) signaling pathway is a novel treatment modality in oncology.... 
CELLS | POTENT | ONCOLOGY | CRYSTAL-STRUCTURE | VEGF | KINASE INHIBITORS | TYROSINE KINASES | TUMOR ANGIOGENESIS | SORAFENIB | CANCER | ENDOTHELIAL GROWTH-FACTOR | Endothelium, Vascular - cytology | Pericytes - drug effects | Apoptosis - drug effects | Humans | Pericytes - cytology | Rats, Inbred F344 | Indoles - chemical synthesis | Endothelium, Vascular - drug effects | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor Receptor-2 - immunology | Enzyme Inhibitors - chemical synthesis | Neoplasms, Experimental - pathology | Tissue Distribution | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Enzyme Inhibitors - pharmacokinetics | Female | Molecular Structure | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Signal Transduction | Pericytes - metabolism | Cells, Cultured | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Rats | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Enzyme Inhibitors - therapeutic use | Xenograft Model Antitumor Assays | Animals | Endothelium, Vascular - metabolism | Mice, Nude | Blood Coagulation Factors - antagonists & inhibitors | Receptors, Fibroblast Growth Factor - metabolism | Indoles - pharmacokinetics | Indoles - therapeutic use | Cell Proliferation - drug effects | Mice | Neoplasms, Experimental - metabolism | Neoplasms, Experimental - drug therapy | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 10/2017, Volume 32, Issue 4, pp. 474 - 489.e6
Journal Article
Gut, ISSN 0017-5749, 03/2017, Volume 66, Issue 3, pp. 530 - 540
ObjectiveSorafenib is effective in hepatocellular carcinoma (HCC), but patients ultimately present disease progression. Molecular mechanisms underlying... 
molecular genetics | stem cells | Hepatocellular carcinoma | molecular mechanisms | drug resistance | GROWTH-FACTOR RECEPTOR | CLASSIFICATION | ACTIVATION | INHIBITION | GASTROENTEROLOGY & HEPATOLOGY | MUTATION | Niacinamide - analogs & derivatives | Humans | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Fibroblast Growth Factors - genetics | Drug Resistance, Neoplasm | Male | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Fibroblast Growth Factors - metabolism | Carcinoma, Hepatocellular - drug therapy | Somatomedins - antagonists & inhibitors | Female | Liver Neoplasms - pathology | Spheroids, Cellular | Somatomedins - metabolism | Gene Expression | Signal Transduction | Liver Neoplasms - drug therapy | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Survival Rate | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Disease Progression | Xenograft Model Antitumor Assays | Animals | Receptors, Somatomedin - metabolism | Somatomedins - genetics | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Aged | Mice | Mice, Inbred BALB C | Fibroblast Growth Factors - antagonists & inhibitors | Receptors, Somatomedin - antagonists & inhibitors | Carcinoma, Hepatocellular - metabolism | Fibroblast growth factors | Hepatoma | Research | Insulin-like growth factor 1 | Index Medicus | Abridged Index Medicus | Liver cancer | Càncer de fetge | Antineoplastic agents | Medicaments antineoplàstics
Journal Article