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Journal Article
The Lancet, ISSN 0140-6736, 2006, Volume 368, Issue 9548, pp. 1696 - 1705
Glucagon-like peptide 1 (GLP-1) is a gut-derived incretin hormone that stimulates insulin and suppresses glucagon secretion, inhibits gastric emptying, and... 
MEDICINE, GENERAL & INTERNAL | IN-VITRO | METFORMIN-TREATED PATIENTS | HEALTHY-SUBJECTS | 2ND-PHASE INSULIN-SECRETION | IMPROVES GLYCEMIC CONTROL | BETA-CELL APOPTOSIS | IV INHIBITOR | 7-36 AMIDE | IMPROVED GLUCOSE-TOLERANCE | EXENATIDE SYNTHETIC EXENDIN-4 | Triazoles - administration & dosage | Triazoles - adverse effects | Glucagon-Like Peptide 1 - administration & dosage | Humans | Pyrazines - administration & dosage | Glucagon-Like Peptide 1 - biosynthesis | Dipeptidyl Peptidase 4 | Glucagon-Like Peptide 1 - physiology | Pyrazines - therapeutic use | Adenosine Deaminase Inhibitors | Peptides - administration & dosage | Hypoglycemic Agents - administration & dosage | Adamantane - therapeutic use | Pyrrolidines | Venoms - administration & dosage | Nitriles | Sitagliptin Phosphate | Adamantane - administration & dosage | Adamantane - adverse effects | Adamantane - analogs & derivatives | Triazoles - therapeutic use | Glucagon-Like Peptide 1 - classification | Hypoglycemic Agents - therapeutic use | Receptors, Glucagon - agonists | Drug Administration Schedule | Glucagon-Like Peptide 1 - analogs & derivatives | Venoms - adverse effects | Glycoproteins - antagonists & inhibitors | Clinical Trials as Topic | Glucagon-Like Peptide-1 Receptor | Dipeptidyl-Peptidase IV Inhibitors | Pyrazines - adverse effects | Venoms - therapeutic use | Diabetes Mellitus, Type 2 - drug therapy | Glucagon-Like Peptide 1 - adverse effects | Hypoglycemic Agents - adverse effects | Liraglutide | Peptides - adverse effects | Peptides - therapeutic use | Glucagon-Like Peptide 1 - therapeutic use | Type 2 diabetes | Care and treatment | Diagnosis | Glucagon | Analysis | Dosage and administration | Research | Protease inhibitors | Drug therapy | Proteins | Diabetes | Kinases | Insulin | Rodents
Journal Article
Journal Article
Journal Article
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 05/2011, Volume 13, Issue 5, pp. 394 - 407
Incretin‐based therapies, such as the injectable glucagon‐like peptide‐1 (GLP‐1) receptor agonists and orally administered dipeptidyl peptidase‐4 (DPP‐4)... 
albiglutide | GLP‐1 analogue | CJC‐1134‐PC | GLP‐1 receptor agonists | antidiabetic drug | type 2 diabetes mellitus | LY2189265 | taspoglutide | exenatide once weekly | incretin therapy | Incretin therapy | Exenatide once weekly | Antidiabetic drug | GLP-1 receptor agonists | GLP-1 analogue | Taspoglutide | CJC-1134-PC | Albiglutide | Type 2 diabetes mellitus | HUMAN GLP-1 ANALOG | INSULIN-SECRETION | OPEN-LABEL | INADEQUATE GLYCEMIC CONTROL | TWICE-DAILY EXENATIDE | BODY-WEIGHT | BETA-CELL-FUNCTION | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | ACUTE-PANCREATITIS | TYPE-2 DIABETES-MELLITUS | Glucagon-Like Peptide 1 - administration & dosage | Recombinant Fusion Proteins - pharmacology | Glycated Hemoglobin A - metabolism | Humans | Glycated Hemoglobin A - drug effects | Male | Immunoglobulin Fc Fragments - administration & dosage | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Hyperglycemia - drug therapy | Peptides - administration & dosage | Hypoglycemic Agents - administration & dosage | Venoms - administration & dosage | Female | Glucagon-Like Peptides - analogs & derivatives | Recombinant Fusion Proteins - administration & dosage | Receptors, Glucagon - agonists | Glucagon-Like Peptide 1 - analogs & derivatives | Glucagon-Like Peptide 1 - pharmacology | Biomarkers - blood | Dipeptidyl-Peptidase IV Inhibitors - administration & dosage | Hypoglycemic Agents - pharmacology | Peptides - pharmacology | Glucagon-Like Peptide-1 Receptor | Immunoglobulin Fc Fragments - pharmacology | Venoms - pharmacology | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Liraglutide | Type 2 diabetes | Antigen-antibody reactions | Hyperglycemia | Peptides | Heterocyclic compounds | Glycosylated hemoglobin | Hypoglycemic agents | Glucose | Dextrose
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2016, Volume 55, Issue 40, pp. 12475 - 12478
Glucagon‐like peptide‐1 (GLP‐1) receptor (GLP‐1R), glucagon (GCG) receptor (GCGR), and glucose‐dependent insulinotropic polypeptide (GIP, also known as gastric... 
peptides | protein engineering | antibodies | obesity | dual agonists | DESIGN | RODENTS | SAFETY | OXYNTOMODULIN | CHEMISTRY, MULTIDISCIPLINARY | METABOLISM | GLP-1 ANALOG | BINDING | Antibodies - metabolism | Recombinant Fusion Proteins - pharmacology | Humans | Peptides - genetics | Body Weight - drug effects | Half-Life | Receptors, Gastrointestinal Hormone - agonists | Glucagon - agonists | Immunoglobulin Light Chains - genetics | Glucagon-Like Peptide 1 - immunology | Peptides - metabolism | Glucagon - immunology | Glucagon-Like Peptide 1 - agonists | HEK293 Cells | Protein Engineering | Antibodies - immunology | Female | Immunoglobulin Heavy Chains - immunology | Immunoglobulin Light Chains - immunology | Recombinant Fusion Proteins - biosynthesis | Peptides - chemistry | Rats | Receptors, Gastrointestinal Hormone - immunology | Rats, Sprague-Dawley | Immunoglobulin Light Chains - metabolism | Animals | Recombinant Fusion Proteins - pharmacokinetics | Immunoglobulin Heavy Chains - metabolism | Antibodies - genetics | Mice, Obese | Mice | Immunoglobulin Heavy Chains - genetics | Proteins | Viral antibodies | Chorionic gonadotropin | Glucagon | Antibodies | Glucose | Cholecystokinin | Dextrose | Rodents | Polypeptides | Peptides | Body weight | Chains | GIP protein | Receptors | N-Terminus | Weight reduction | Glucagon-like peptide 1 | Half life
Journal Article