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1. Full Text Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer
by Bayne, Lauren J and Beatty, Gregory L and Jhala, Nirag and Clark, Carolyn E and Rhim, Andrew D and Stanger, Ben Z and Vonderheide, Robert H
Cancer Cell, ISSN 1535-6108, 06/2012, Volume 21, Issue 6, pp. 822 - 835
Cancer-associated inflammation is thought to be a barrier to immune surveillance, particularly in pancreatic ductal adenocarcinoma (PDA). Gr-1 CD11b cells are... 
OVEREXPRESSION | MICROENVIRONMENT | ONCOLOGY | DUCTAL ADENOCARCINOMA | INTERLEUKIN-1-BETA | MICE | SUPPRESSOR-CELLS | INDUCTION | DIFFERENTIATION | MAMMARY CARCINOMAS | MOUSE MODELS | CELL BIOLOGY | Immunohistochemistry | Adenocarcinoma - pathology | CD8-Positive T-Lymphocytes - pathology | Pancreatic Neoplasms - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Humans | Carcinoma, Pancreatic Ductal - metabolism | Inflammation - metabolism | Adenocarcinoma - metabolism | RNA Interference | T-Lymphocytes - metabolism | Myeloid Cells - immunology | CD8-Positive T-Lymphocytes - metabolism | T-Lymphocytes - pathology | Carcinoma, Pancreatic Ductal - immunology | CD11b Antigen - immunology | Adenocarcinoma - immunology | Pancreatic Neoplasms - pathology | Receptors, Chemokine - metabolism | Mice, Transgenic | Inflammation - immunology | Receptors, Chemokine - immunology | Carcinoma, Pancreatic Ductal - pathology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Tumor Microenvironment - immunology | Models, Immunological | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Pancreatic Neoplasms - immunology | Cell Line, Tumor | Myeloid Cells - metabolism | T-Lymphocytes - immunology | Mice | CD11b Antigen - metabolism | Myeloid Cells - pathology | CD8-Positive T-Lymphocytes - immunology | Medical colleges | Analysis | Pancreatic cancer | Oncology, Experimental | Genetically modified organisms | Inflammation | Macrophage colony stimulating factor | Research | T cells | Tumors | Cancer | granulocyte-macrophage colony stimulating factor | myeloid cells | T lymphocyte | carcinoma | pancreas
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2. Full Text The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance
by Stachura, David L and Stachura, David L and Svoboda, Ondrej and Svoboda, Ondřej and Campbell, Clyde A and Campbell, Clyde A and Espín-Palazón, Raquel and Espín-Palazón, Raquel and Lau, Ryan P and Lau, Ryan P and Zon, Leonard I and Zon, Leonard I and Bartunek, Petr and Bartůněk, Petr and Traver, David and Traver, David
Blood, ISSN 0006-4971, 2013, Volume 122, Issue 24, pp. 3918 - 3928
Granulocyte colony-stimulating factor (Gcsf) drives the proliferation and differentiation of granulocytes, monocytes, and macrophages (mws) from hematopoietic... 
FACTOR-RECEPTOR | PROGENITOR CELLS | STEM-CELLS | DEFINITIVE HEMATOPOIESIS | GM-CSF | IN-VITRO DIFFERENTIATION | GROWTH-FACTOR | FACTOR GENES | HEMATOLOGY | G-CSF | EXPRESSION | Myelopoiesis - genetics | Embryo, Nonmammalian - metabolism | Embryo, Nonmammalian - embryology | Male | Receptors, Granulocyte Colony-Stimulating Factor - genetics | Zebrafish - embryology | Gene Knockdown Techniques | Granulocyte Colony-Stimulating Factor - genetics | In Situ Hybridization | Gene Expression Regulation, Developmental | Female | Receptors, Granulocyte Colony-Stimulating Factor - metabolism | Hematopoietic System - embryology | Granulocyte Colony-Stimulating Factor - metabolism | Animals, Genetically Modified | Zebrafish Proteins - metabolism | Hematopoiesis - genetics | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Zebrafish - genetics | Microscopy, Confocal | Animals | Hematopoietic System - metabolism | Ligands | Luminescent Proteins - genetics | Zebrafish Proteins - genetics | Luminescent Proteins - metabolism | Hematopoiesis and Stem Cells
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3. Full Text Regulation of myeloid development and function by colony stimulating factors
by Barreda, Daniel R and Hanington, Patrick C and Belosevic, Miodrag
Developmental and Comparative Immunology, ISSN 0145-305X, 2004, Volume 28, Issue 5, pp. 509 - 554
The colony-stimulating factors (CSFs) are a group of cytokines central to the hematopoiesis of blood cells, the modulation of their functional responses, as... 
Signal transduction | Function | GM-CSF | Multi-CSF/IL-3 | Colony-stimulating factors | Proliferation | Differentiation | M-CSF/CSF-1 | G-CSF | Hemopoiesis/hematopoiesis | Y-PSEUDOAUTOSOMAL REGION | FMS PROTO-ONCOGENE | differentiation | hemopoiesis/hematopoiesis | proliferation | signal transduction | HUMAN-ENDOTHELIAL CELLS | SEVERE CONGENITAL NEUTROPENIA | BONE-MARROW-CELLS | COMMON BETA-SUBUNIT | IMMUNOLOGY | HEMATOPOIETIC GROWTH-FACTORS | TUMOR-NECROSIS-FACTOR | FISHERIES | ZOOLOGY | function | MONOCYTE-DERIVED MACROPHAGES | GM-CSF RECEPTOR | multi-CSF/IL-3 | colony-stimulating factors | Granulocyte Colony-Stimulating Factor - physiology | Myelopoiesis - physiology | Signal Transduction | Humans | Receptors, Interleukin-3 - genetics | Receptor, Macrophage Colony-Stimulating Factor - genetics | Receptors, Granulocyte Colony-Stimulating Factor - genetics | Granulocyte-Macrophage Colony-Stimulating Factor - physiology | Colony-Stimulating Factors - genetics | Interleukin-3 - genetics | Receptors, Granulocyte Colony-Stimulating Factor - physiology | Granulocyte Colony-Stimulating Factor - genetics | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Animals | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - physiology | Receptor, Macrophage Colony-Stimulating Factor - physiology | Colony-Stimulating Factors - physiology | Macrophage Colony-Stimulating Factor - genetics | Macrophage Colony-Stimulating Factor - physiology | Interleukin-3 - physiology | Receptors, Interleukin-3 - physiology
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4. Full Text Zebrafish granulocyte colony-stimulating factor receptor signaling promotes myelopoiesis and myeloid cell migration
by Liongue, Clifford and Hall, Chris J and O'Connell, Bree A and Crosier, Phil and Ward, Alister C
Blood, ISSN 0006-4971, 03/2009, Volume 113, Issue 11, pp. 2535 - 2546
Granulocyte colony-stimulating factor receptor (GCSFR) signaling participates in the production of neutrophilic granulocytes during normal hematopoietic... 
TRANSCRIPTION FACTORS | PROGENITOR CELLS | ACTIVATION | HEMATOPOIESIS | BONE-MARROW | TRANSGENIC FISH | G-CSF RECEPTOR | EXPRESSION PATTERN | HEMATOLOGY | FACTOR GENE | BLOOD | Amino Acid Sequence | Myeloid Progenitor Cells - metabolism | Animals, Genetically Modified | Myeloid Cells - physiology | Myelopoiesis - genetics | Molecular Sequence Data | Hematopoiesis - genetics | Receptors, Granulocyte Colony-Stimulating Factor - genetics | Signal Transduction - genetics | Phylogeny | Zebrafish - embryology | Cell Movement - genetics | Receptors, Granulocyte Colony-Stimulating Factor - physiology | Zebrafish - genetics | Sequence Homology, Amino Acid | Animals | Myeloid Progenitor Cells - physiology | Gene Expression Regulation, Developmental | Embryo, Nonmammalian | Myeloid Cells - metabolism | Zebrafish - physiology | Receptors, Granulocyte Colony-Stimulating Factor - metabolism
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5. Full Text Granulocyte colony-stimulating factor receptor: Stimulating granulopoiesis and much more
by Liongue, Clifford and Wright, Craig and Russell, Aaron P and Ward, Alister C
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 2009, Volume 41, Issue 12, pp. 2372 - 2375
The granulocyte colony-stimulating factor receptor (G-CSFR) plays an important role in the production, survival and activation of neutrophilic granulocytes... 
Signaling | Hematopoiesis | G-CSF | Cytokine receptor | BIOCHEMISTRY & MOLECULAR BIOLOGY | RATS | PROLIFERATION | CELL BIOLOGY | PATHWAY | CELL-MIGRATION | GROWTH | DISEASE | CARCINOMAS | EXPRESSION | Myeloid Cells - cytology | Neoplasms - metabolism | Cell Survival | Humans | Liver - metabolism | Receptors, Granulocyte Colony-Stimulating Factor - genetics | Recombinant Proteins | Granulocyte Colony-Stimulating Factor - therapeutic use | Mutation - genetics | Neurogenesis | Neutropenia - congenital | Neoplasms - therapy | Animals | Myeloid Cells - immunology | Neoplasms - immunology | Bone Marrow Transplantation | Myeloid Cells - metabolism | Hematopoietic Stem Cell Mobilization | Receptors, Granulocyte Colony-Stimulating Factor - metabolism | Muscles - metabolism | Receptors, Granulocyte Colony-Stimulating Factor - immunology | Cell Movement | Neutropenia - immunology | Medical colleges | Granulocyte colony-stimulating factor | Ponds | Leukemia | Development and progression | Macrophage colony stimulating factor | Peptide hormones | Growth factors | Hematopoietic stem cells
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6. Full Text Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms
by Vainchenker, William and Kralovics, Robert
Blood, ISSN 0006-4971, 02/2017, Volume 129, Issue 6, pp. 667 - 679
The genetic landscape of classicalmyelopro-liferative neoplasm (MPN) is in large part elucidated. The MPN-restricted driver mutations, including those in JAK2,... 
POLYCYTHEMIA-VERA | ACTIVATING MUTATION | CLONAL HEMATOPOIESIS | ACQUIRED UNIPARENTAL DISOMY | JAK2 V617F MUTATION | ACUTE MYELOID-LEUKEMIA | ESSENTIAL THROMBOCYTHEMIA | HEMATOLOGY | CHRONIC MYELOMONOCYTIC LEUKEMIA | THROMBOPOIETIN RECEPTOR | DISEASE PROGRESSION | Thrombocythemia, Essential - physiopathology | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | STAT Transcription Factors - metabolism | Polycythemia Vera - genetics | Receptors, Granulocyte Colony-Stimulating Factor - genetics | Thrombocythemia, Essential - genetics | Calreticulin - genetics | Receptors, Erythropoietin - genetics | DNA (Cytosine-5-)-Methyltransferases - metabolism | DNA-Binding Proteins - metabolism | Polycythemia Vera - metabolism | Janus Kinase 2 - metabolism | Calreticulin - metabolism | Receptors, Granulocyte Colony-Stimulating Factor - metabolism | Polycythemia Vera - physiopathology | Primary Myelofibrosis - metabolism | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Primary Myelofibrosis - physiopathology | Janus Kinase 2 - genetics | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Receptors, Thrombopoietin - metabolism | Disease Progression | DNA (Cytosine-5-)-Methyltransferases - genetics | Receptors, Thrombopoietin - genetics | Primary Myelofibrosis - genetics | STAT Transcription Factors - genetics | Mutation | Receptors, Erythropoietin - metabolism | Thrombocythemia, Essential - metabolism
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7. Full Text Role of stem cell factor and granulocyte colony‐stimulating factor in remodeling during liver regeneration
by Meng, Fanyin and Francis, Heather and Glaser, Shannon and Han, Yuyan and DeMorrow, Sharon and Stokes, Allison and Staloch, Dustin and Venter, Julie and White, Melanie and Ueno, Yoshiyuki and Reid, Lola M and Alpini, Gianfranco
Hepatology, ISSN 0270-9139, 01/2012, Volume 55, Issue 1, pp. 209 - 221
Functional pluripotent characteristics have been observed in specific subpopulations of hepatic cells that express some of the known cholangiocyte markers.... 
CHOLANGIOCYTES | GROWTH-FACTOR-BETA | NECROSIS | EPITHELIAL-CELLS | EXPANSION | C-KIT | RECEPTOR | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Humans | Rats, Inbred F344 | Male | MicroRNAs - metabolism | Stem Cell Factor - genetics | Cytokines - physiology | Granulocyte Colony-Stimulating Factor - genetics | Hepatectomy | Hepatocytes - cytology | Receptors, Colony-Stimulating Factor - genetics | Receptors, Colony-Stimulating Factor - metabolism | Epithelial Cells - cytology | Bile Ducts, Intrahepatic - cytology | Granulocyte Colony-Stimulating Factor - metabolism | Hepatocytes - physiology | Bile Ducts, Intrahepatic - physiology | Pluripotent Stem Cells - cytology | Stem Cell Factor - metabolism | Pluripotent Stem Cells - physiology | Rats | Matrix Metalloproteinase 3 - metabolism | Liver Regeneration - physiology | Cell Division - physiology | Animals | Liver - physiology | Signal Transduction - physiology | Liver - cytology | Mice | Mice, Inbred BALB C | Transforming Growth Factor beta - metabolism | Cell Line, Transformed | Cytokines | Granulocytes | Rodents | Stem cells | TIMP-3 | Stem cell factor (SCF) | biliary remodeling | Granulocyte | partial hepatectomy (PH) | macrophage colony stimulating factor (GM-CSF) | Colony stimulating factors (CSFs) | liver regeneration | miR-181
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8. Full Text Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies
by Dwivedi, Pankaj and Greis, Kenneth D
Experimental Hematology, ISSN 0301-472X, 2016, Volume 46, pp. 9 - 20
Granulocyte colony-stimulating factor is a hematopoietic cytokine that stimulates neutrophil production and hematopoietic stem cell mobilization by initiating... 
Hematology, Oncology and Palliative Medicine | Advanced Basic Science | Genetic Predisposition to Disease | Signal Transduction | Neutropenia - metabolism | Receptors, Granulocyte Colony-Stimulating Factor - chemistry | Humans | Leukemia, Myeloid, Acute - metabolism | STAT Transcription Factors - metabolism | Janus Kinases - metabolism | Leukemia, Myeloid, Acute - etiology | Phosphatidylinositol 3-Kinases - metabolism | Receptors, Granulocyte Colony-Stimulating Factor - genetics | Cell Transformation, Neoplastic - metabolism | Neutropenia - congenital | Leukemia, Neutrophilic, Chronic - etiology | MAP Kinase Signaling System | Neutropenia - etiology | Animals | Cell Transformation, Neoplastic - genetics | Protein Interaction Domains and Motifs - genetics | Protein Binding | Leukemia, Neutrophilic, Chronic - metabolism | Mutation | Receptors, Granulocyte Colony-Stimulating Factor - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Medical colleges | Genetic disorders | Granulocyte colony-stimulating factor | Analysis | Leukemia | Macrophage colony stimulating factor | Hematopoietic stem cells | Neutropenia | intracellular truncation mutations |