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Journal of Clinical Investigation, ISSN 0021-9738, 09/2011, Volume 121, Issue 9, pp. 3564 - 3577
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2014, Volume 124, Issue 3, pp. 1187 - 1198
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 129, Issue 4, pp. 1102 - 1115
Background Sequestration of IgE to prevent its binding to high-affinity IgE receptor FcϵRI on basophils and mast cells is an effective therapy for allergic... 
Allergy and Immunology | Allergy | inhibitory receptor | IgE | humanized mice | therapeutic antibody | asthma | FcεRI | omalizumab | FcγRIIb | plasma cell | Fc gamma RIIb | Fc epsilon RI | MAST-CELLS | IMMUNOLOGY | PLASMA-CELLS | THERAPY | INHIBITION | ALLERGIC-ASTHMA | IN-VIVO | MONOCLONAL-ANTIBODIES | EPSILON-RI | AFFINITY RECEPTOR | IMMUNOGLOBULIN-E | Leukocytes, Mononuclear - metabolism | Immunoglobulin G - blood | Antibodies, Anti-Idiotypic - pharmacology | Humans | Immunoglobulin E - biosynthesis | Omalizumab | Antibody Affinity - immunology | Anti-Allergic Agents - pharmacology | Receptors, Antigen, B-Cell - metabolism | Receptors, IgG - antagonists & inhibitors | Antibodies, Monoclonal, Humanized - genetics | Receptors, IgG - metabolism | Lymphocyte Activation - immunology | Receptors, IgG - genetics | Immunoglobulin G - biosynthesis | Antibodies, Monoclonal, Humanized - blood | Antibodies, Monoclonal, Humanized - pharmacology | Leukocytes, Mononuclear - transplantation | Antibodies, Anti-Idiotypic - blood | Immunoglobulin E - metabolism | Mice, Inbred C57BL | Antibodies, Anti-Idiotypic - immunology | Receptors, IgE - antagonists & inhibitors | Receptors, Antigen, B-Cell - antagonists & inhibitors | Mice, SCID | Protein Binding - immunology | Mice, Knockout | B-Lymphocytes - drug effects | Animals | B-Lymphocytes - immunology | Immunoglobulin M - blood | Receptors, IgE - metabolism | Mice | Immunoglobulin Fc Fragments - genetics | Immunoglobulin M - biosynthesis
Journal Article
Clinical & Experimental Allergy, ISSN 0954-7894, 05/2014, Volume 44, Issue 5, pp. 701 - 712
Summary Background Chronic rhinosinusitis with nasal polyps is generally characterized by local Th2 inflammation and is categorized into two subtypes in Japan:... 
sinusitis | eosinophil | nasal polyp | class switch | IgE | Class switch | Nasal polyp | Eosinophil | Sinusitis | BRONCHIAL BIOPSIES | INDUCED CYTIDINE DEAMINASE | IL-5 MESSENGER-RNA | HUMAN B-CELLS | ALLERGIC RHINITIS | IMMUNOLOGY | NONATOPIC ASTHMA | HEAVY-CHAIN | RECEPTOR REVISION | ALLERGY | POSITION PAPER | EXPRESSION | Nasal Polyps - etiology | Homeodomain Proteins - metabolism | Humans | Middle Aged | Immunoglobulin Class Switching - immunology | Male | Rhinitis - diagnosis | Nasal Mucosa - pathology | Nasal Polyps - diagnosis | Eosinophils - immunology | Sinusitis - complications | DNA-Binding Proteins - metabolism | Inflammation - metabolism | Immunoglobulin E - immunology | Immunoglobulin E - genetics | Immunoglobulin G - immunology | Adult | B-Lymphocyte Subsets - immunology | Female | Leukocyte Count | Nasal Mucosa - metabolism | Nuclear Proteins - genetics | Cytokines - genetics | Cytokines - metabolism | Sinusitis - diagnosis | Immunoglobulin E - metabolism | Gene Expression Regulation | Nuclear Proteins - metabolism | Inflammation - immunology | Receptors, IgE - genetics | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Phenotype | Immunoglobulin G - genetics | B-Lymphocyte Subsets - metabolism | Receptors, IgE - metabolism | Nasal Mucosa - immunology | Rhinitis - complications | Aged | Chronic Disease | Immunoglobulin Class Switching - genetics | Immunoglobulin E | RNA | Methylation | Nasal polyps | Analysis | Medical research | Immunoglobulins | Allergies
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2009, Volume 4, Issue 7, pp. e6153 - e6153
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 137, Issue 6, pp. 1631 - 1645
Fifty years ago, after a long search, IgE emerged as the circulating factor responsible for triggering allergic reactions. Its extremely low concentration in... 
Allergy and Immunology | mast cells | IgE | anaphylaxis | FC-EPSILON-RI | LOW-AFFINITY RECEPTOR | IMMUNOLOGY | MAST-CELL SURVIVAL | PLASMACYTOID DENDRITIC CELLS | HISTAMINE-RELEASING FACTOR | ALLERGY | IN-VIVO | X-LINKED IMMUNODEFICIENCY | CLASS-SWITCH RECOMBINATION | BASOPHILIC LEUKEMIA-CELLS | ANTI-IGE | Mast Cells - immunology | Antibody Formation - immunology | Cytokines - metabolism | Immunomodulation | Humans | Immunoglobulin Class Switching - immunology | Hypersensitivity - immunology | Immunity | Immunoglobulin E - chemistry | Animals | B-Lymphocytes - immunology | Immunoglobulin E - immunology | Hypersensitivity - metabolism | Immunoglobulin E - genetics | Receptors, IgE - metabolism | Mast Cells - metabolism | Anaphylaxis - immunology | Hypersensitivity - genetics | Immunologic Memory | Anaphylaxis - metabolism | Immunoglobulin Class Switching - genetics | Antibody Formation - genetics | B-Lymphocytes - metabolism | Immunoglobulin E | Allergy | Allergic reaction | Tyrosine | Antigens | Histamine | Dendritic cells | Albumin | Food allergies | Immunoglobulins | Cytokines | Genes | T cell receptors | Inflammation | RNA polymerase | Kinases | Asthma | Human subjects | Signal transduction | Lymphocytes | Ligands | Genetic engineering | Adapter proteins | Deoxyribonucleic acid--DNA | peanut allergy | tryptase | humanized mice
Journal Article