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Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 6/2011, Volume 108, Issue 24, pp. 9927 - 9932
Cross-presentation of IgG-containing immune complexes (ICs) is an important means by which dendritic cells (DCs) activate CD8... 
T lymphocytes | Antigens | Fc receptors | Cross priming | Dendritic cells | Internalization | Phagosomes | Inflammation | Oxidation | MHC CLASS-I | GAMMA-RECEPTOR | CD8(+) | VIVO | MULTIDISCIPLINARY SCIENCES | DISEASE | MONOCYTES | ANTIGEN PRESENTATION | MYASTHENIA-GRAVIS | T-CELLS | CUTTING EDGE | Dextran Sulfate | Membrane Glycoproteins - metabolism | Cytosol - immunology | Dendritic Cells - immunology | Receptors, Fc - metabolism | NADPH Oxidases - metabolism | NADPH Oxidases - immunology | Vacuolar Proton-Translocating ATPases - metabolism | Receptors, IgG - metabolism | Histocompatibility Antigens Class I - metabolism | Vacuolar Proton-Translocating ATPases - immunology | Phagosomes - immunology | Flow Cytometry | Immunoglobulin G - immunology | Colitis - chemically induced | Membrane Glycoproteins - immunology | Colitis - immunology | Dendritic Cells - metabolism | rab GTP-Binding Proteins - metabolism | CD11b Antigen - immunology | Mice, Inbred C57BL | Phagosomes - metabolism | Histocompatibility Antigens Class I - immunology | Mice, Transgenic | Histocompatibility Antigens Class I - genetics | Receptors, IgG - immunology | NADPH Oxidase 2 | Blotting, Western | CD8 Antigens - immunology | Mice, Knockout | CD8 Antigens - metabolism | Animals | Immunoglobulin G - genetics | Receptors, Fc - immunology | Cross-Priming - immunology | rab GTP-Binding Proteins - immunology | Colitis - metabolism | Protein Binding | rab27 GTP-Binding Proteins | Antigens - immunology | Cytosol - metabolism | Receptors, Fc - genetics | Mice | CD11b Antigen - metabolism | Mutation | Hydrogen-Ion Concentration | Immunoglobulin G - metabolism | Biological Sciences
Journal Article
The Journal of clinical investigation, ISSN 1558-8238, 2015, Volume 125, Issue 11, pp. 4160 - 4170
IgG molecules exert both pro- and antiinflammatory effector functions based on the composition of the fragment crystallizable (Fc) domain glycan... 
RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | ANTIINFLAMMATORY ACTIVITY | EFFECTOR FUNCTIONS | IN-VIVO | BINDING-SITE | ANTIBODY | GLYCOSYLATION | GAMMA-RIV | RECEPTORS | IMMUNOGLOBULIN-G | Myelin-Oligodendrocyte Glycoprotein - immunology | Complement C1q - immunology | Humans | Complement System Proteins - immunology | Lymphocyte Depletion | Complement C1q - metabolism | Burkitt Lymphoma - pathology | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - immunology | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - therapy | Immunoglobulin G - immunology | Killer Cells, Natural - immunology | Rituximab - chemistry | Complement Pathway, Classical | Antigens, CD20 - immunology | Antibody-Dependent Cell Cytotoxicity | Immunoglobulin G - chemistry | Glycosylation | Receptors, IgG - immunology | N-Acetylneuraminic Acid - chemistry | Animals | B-Lymphocytes - immunology | Immunoglobulin gamma-Chains - chemistry | Immunoglobulin gamma-Chains - immunology | Immunoglobulins, Intravenous - therapeutic use | Cell Line, Tumor | Mice | Protein Processing, Post-Translational | Rituximab - immunology | Cytotoxicity, Immunologic | Antigen-antibody reactions | Genetic aspects | Regulation | Immune response | Properties | Immunoglobulin G | Antigens | Acids | Colleges & universities | Lectins | Cytotoxicity | Software | Autoimmune diseases
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 1, pp. 269 - 280.e7
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2017, Volume 214, Issue 7, pp. 1991 - 2003
... I/i carbohydrates expressed by erythrocytes with a specific motif in their framework region 1 (FWR1). VH4-34–expressing clones are common in the naive B cell repertoire but are rarely found in IgG memory B cells from healthy individuals... 
AUTOANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNE-RESPONSE | SYSTEMIC-LUPUS-ERYTHEMATOSUS | INNATE | HUMANS | IRAK-4 | GERMINAL-CENTERS | IMMUNOLOGY | CLASS SWITCH | SELECTION | MYD88 | Clonal Selection, Antigen-Mediated | Interleukin-1 Receptor-Associated Kinases - genetics | Humans | Antigens, Bacterial - immunology | Child, Preschool | Interleukin-1 Receptor-Associated Kinases - deficiency | Male | Immunoglobulin Variable Region - immunology | Young Adult | Bacteria - immunology | Immunoglobulin G - immunology | Interleukin-1 Receptor-Associated Kinases - immunology | Myeloid Differentiation Factor 88 - immunology | Adult | Female | Child | Immunoglobulin Heavy Chains - immunology | B-Lymphocytes - metabolism | Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology | Amino Acid Sequence | Myeloid Differentiation Factor 88 - genetics | Sequence Homology, Amino Acid | Autoantibodies - immunology | B-Lymphocytes - immunology | Immunoglobulin G - genetics | Myeloid Differentiation Factor 88 - deficiency | Tumor Necrosis Factor Receptor Superfamily, Member 7 - metabolism | Adolescent | Immunoglobulin Variable Region - genetics | Gastrointestinal Microbiome - immunology | Mutation | Autoantibodies - genetics | Immunoglobulin Heavy Chains - genetics | CD27 antigen | Immunoglobulin G | Erythrocytes | Antibodies | Proteins | Receptors | Red blood cells | Toll-like receptors | Bacteria | Containment | Immune system | Carbohydrates | Antigens | Immunological memory | Memory cells | Immunoglobulins | Cloning | T cell receptors | Patients | TLR3 protein | Somatic hypermutation | Lymphocytes B | MyD88 protein | Receptor mechanisms | 310
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2018, Volume 215, Issue 1, pp. 91 - 113
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2015, Volume 212, Issue 9, pp. 1361 - 1369
Journal Article
Nature immunology, ISSN 1529-2908, 08/2017, Volume 18, Issue 8, pp. 889 - 889
Engineered crystallizable fragment (Fc) regions of antibody domains, which assume a unique and unprecedented asymmetric structure within the homodimeric Fc... 
DEPENDENT CELLULAR CYTOTOXICITY | MOUSE COMPLEMENT | CELLS | ACTIVATION | AFFINITY | RITUXIMAB | GLYCOSYLATION | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | THERAPEUTIC ACTIVITY | HUMAN CD20 | Surface Plasmon Resonance | Precursor Cell Lymphoblastic Leukemia-Lymphoma - immunology | Immunoglobulin Fc Fragments - metabolism | Complement C1q - immunology | Humans | Crystallography, X-Ray | Complement C1q - metabolism | Receptors, IgG - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Tandem Mass Spectrometry | Immunoglobulin Fc Fragments - immunology | Burkitt Lymphoma - immunology | Immunoglobulin G - immunology | Immunotherapy | Mass Spectrometry | Lymphoma, B-Cell - immunology | Chromatography, Liquid | Lymphoma, Large B-Cell, Diffuse - immunology | Burkitt Lymphoma - drug therapy | Lymphoma, B-Cell - drug therapy | Lymphoma, Large B-Cell, Diffuse - drug therapy | Enzyme-Linked Immunosorbent Assay | Crystallization | Phagocytosis - immunology | Antibodies, Monoclonal | Receptors, IgG - immunology | Neoplasms - drug therapy | Animals | Neoplasms - immunology | Cell Line, Tumor | Mice | Chromatography, Gel | Cytotoxicity, Immunologic - immunology | In Vitro Techniques | Immunoglobulin G - metabolism | Lymphoma, Large B-Cell, Diffuse | Immunoglobulin G | Lymphoma, B-Cell | Neoplasms | Life Sciences | Immunology | Immunoglobulin Fc Fragments | Burkitt Lymphoma | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Complement C1q | Receptors, IgG | Phagocytosis | Cytotoxicity, Immunologic | X-ray crystallography | Complement cascade | Cellular immunity | BASIC BIOLOGICAL SCIENCES | Cancer therapy
Journal Article
Nature reviews. Immunology, ISSN 1474-1741, 2013, Volume 13, Issue 3, pp. 176 - 189
Intravenous immunoglobulin (IVIG) preparations comprise pooled IgG antibodies from the serum of thousands of donors and were initially used as an IgG replacement therapy in immunocompromised patients... 
IDIOPATHIC THROMBOCYTOPENIC PURPURA | IVIG-MEDIATED AMELIORATION | B-CELLS | RHEUMATOID-ARTHRITIS | FC-GAMMA-RECEPTOR | ANTI-D IMMUNOGLOBULIN | ANTIINFLAMMATORY ACTIVITY | DENDRITIC CELLS | REGULATORY T-CELLS | HIGH-AFFINITY BINDING | IMMUNOLOGY | Immunomodulation - drug effects | Humans | Lectins, C-Type - immunology | Receptors, IgG - chemistry | Cell Adhesion Molecules - immunology | Immunoglobulin Variable Region - immunology | Lymphocyte Subsets - immunology | Immunoglobulin Fc Fragments - immunology | Immunoglobulin G - immunology | Immunoglobulin G - pharmacology | Disease Models, Animal | N-Acetylneuraminic Acid - immunology | Autoimmune Diseases - immunology | Histocompatibility Antigens Class I - immunology | Immunoglobulin G - therapeutic use | Models, Molecular | Clinical Trials as Topic | Glycosylation | Inflammation - immunology | Receptors, IgG - immunology | Immunoglobulins, Intravenous - pharmacology | Receptors, Cell Surface - immunology | Inflammation - therapy | Autoantibodies - immunology | Immunosuppression | Animals | Receptors, Fc - immunology | Immunoglobulins, Intravenous - therapeutic use | Autoimmune Diseases - therapy | Protein Conformation | Mice | Protein Processing, Post-Translational | Immunocompromised Host | Immunomodulation - immunology | Receptors, IgG - classification | Care and treatment | Immunoglobulin G | Immunotherapy | Physiological aspects | Research | Autoimmune diseases | Health aspects | Thrombocytopenia | Immunoglobulins | Intravenous administration | Reviews | Immunocompromised hosts | Inflammatory diseases | Immune system
Journal Article