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Journal of virology, ISSN 1098-5514, 09/2012, Volume 86, Issue 18, pp. 9888 - 9898
Chikungunya virus (CHIKV) infections can produce severe disease and mortality. Here we show that CHIKV infection of adult mice deficient in interferon response factors 3 and 7 (IRF3/7 ) is lethal... 
Life Sciences & Biomedicine | Science & Technology | Virology | Interferon-alpha - pharmacology | Shock, Hemorrhagic - prevention & control | Humans | Adaptor Proteins, Vesicular Transport - deficiency | Adaptor Proteins, Vesicular Transport - genetics | Receptor, Interferon alpha-beta - physiology | Interferon Regulatory Factor-7 - genetics | Interferon Regulatory Factor-3 - genetics | Host-Pathogen Interactions - immunology | Alphavirus Infections - prevention & control | Interferon Regulatory Factor-7 - physiology | Chikungunya virus - physiology | Receptor, Interferon alpha-beta - genetics | Chikungunya virus - pathogenicity | Chikungunya Fever | Virus Replication - drug effects | Adaptor Proteins, Vesicular Transport - physiology | Interferon-alpha - biosynthesis | Receptor, Interferon alpha-beta - deficiency | Mice, Inbred C57BL | Myeloid Differentiation Factor 88 - genetics | Interferon-beta - biosynthesis | Alphavirus Infections - immunology | Chikungunya virus - immunology | Alphavirus Infections - pathology | Interferon Regulatory Factor-3 - physiology | Mice, Knockout | Animals | Interferon Regulatory Factor-3 - deficiency | Myeloid Differentiation Factor 88 - deficiency | Host-Pathogen Interactions - genetics | Interferon Regulatory Factor-7 - deficiency | Myeloid Differentiation Factor 88 - physiology | Mice | Shock, Hemorrhagic - immunology | Index Medicus | Life Sciences | Santé publique et épidémiologie | Pathogenesis and Immunity
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 06/2018, Volume 141, Issue 6, pp. 2234 - 2248
The homozygous K108E mutation of interferon regulatory factor 8 (IRF8) is reported to cause dendritic cell (DC... 
Interferon regulatory factor 8 | monocyte | immunodeficiency | interferon | dendritic cell | myeloproliferation | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Humans | Monocytes - pathology | Dendritic Cells - pathology | Immunologic Deficiency Syndromes - genetics | Interferon Regulatory Factors - genetics | Male | Mutation | Immunologic Deficiency Syndromes - immunology | Virus diseases | Killer cells | Memory (Computers) | Dendritic cells | Analysis | Immunodeficiency | Genetic research | Genetic aspects | Interferon | Biological response modifiers | T cells | Flow cytometry | Profiling | Transcription | Identification methods | CD8 antigen | Differentiation (biology) | Helper cells | Dermis | Lymphocytes T | Infections | Immunity | Defects | Complexity | Proteins | Granulocytes | Lymphocytes | Hematopoiesis | Natural killer cells | Age | Translocation | Sequences | Immunoglobulins | Immunological memory | Memory cells | Phenotypes | Recurrent infection | T cell receptors | CXCR3 protein | Gene expression | Cell differentiation | Patients | Nuclear transport | Hemopoiesis | Computer memory | Somatic hypermutation | Monocytes | Lymphocytes B | Lungs | Calcification | Leukocytes (granulocytic) | Interferon regulatory factor | Viral infections | ISRE, Interferon-stimulated response element | EICE, Ets–interferon regulatory factor composite element | IRF, Interferon regulatory factor | SSC, Side scatter | TLR, Toll-like receptor | pDC, Plasmacytoid dendritic cell | STAT, Signal transducer and activator of transcription | Treg, Regulatory T | TF, Transcription factor | BAL, Bronchoalveolar lavage | DC, Dendritic cell | CDR3, Complementarity-determining region 3 | IAD, Interferon regulatory factor–associated domain | AICE, Activator protein 1–interferon regulatory factor composite element | EMSA, Electrophoretic mobility shift assay | HA, Hemagglutinin | cDC, Conventional dendritic cell | NK, Natural killer
Journal Article
PloS one, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, pp. e32863 - e32863
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 03/2007, Volume 178, Issue 5, pp. 3126 - 3133
Journal Article
Journal of hepatology, ISSN 0168-8278, 05/2011, Volume 54, Issue 5, pp. 887 - 893
Journal Article