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Nature immunology, ISSN 1529-2916, 06/2015, Volume 16, Issue 8, pp. 838 - 849
Interferon-gamma (IFN-gamma) primes macrophages for enhanced microbial killing and inflammatory activation by Toll-like receptors (TLRs... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Toll-Like Receptor 2 - genetics | TOR Serine-Threonine Kinases - metabolism | Homeodomain Proteins - metabolism | Humans | Protein Biosynthesis - immunology | Eukaryotic Initiation Factor-4E - metabolism | Multiprotein Complexes - genetics | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Multiprotein Complexes - metabolism | TOR Serine-Threonine Kinases - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | RNA Interference | Base Sequence | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Macrophage Activation - immunology | Signal Transduction - genetics | Toll-Like Receptor 2 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Macrophages - metabolism | Signal Transduction - drug effects | Toll-Like Receptor 2 - immunology | Protein Biosynthesis - drug effects | MicroRNAs - genetics | Multiprotein Complexes - immunology | RNA, Messenger - immunology | Transcription Factor HES-1 | Macrophage Activation - genetics | Intracellular Signaling Peptides and Proteins - immunology | Homeodomain Proteins - immunology | Mechanistic Target of Rapamycin Complex 1 | Signal Transduction - immunology | Eukaryotic Initiation Factor-4E - immunology | Protein Biosynthesis - genetics | Eukaryotic Initiation Factor-4E - genetics | Macrophages - immunology | RNA, Messenger - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Homeodomain Proteins - genetics | TOR Serine-Threonine Kinases - immunology | Interferon-gamma - immunology | Basic Helix-Loop-Helix Transcription Factors - immunology | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Macrophage Activation - drug effects | Interferon-gamma - pharmacology | Microscopy, Fluorescence | Index Medicus
Journal Article
Journal Article
Journal of virology, ISSN 1098-5514, 01/2017, Volume 91, Issue 1
.... Interferon regulatory factor 1 (IRF-1) is a tumor suppressor that is also involved in the regulation of innate and adaptive immune responses... 
Acute infection | Interferon | IRF-1 | Viral replication | Gammaherpesvirus | Spleen - virology | Interferon-Induced Helicase, IFIH1 - genetics | Interferon-beta - immunology | Spleen - immunology | Herpesviridae Infections - mortality | Humans | Gammaherpesvirinae - pathogenicity | Interferon Regulatory Factor-7 - genetics | Interferon Regulatory Factor-3 - genetics | Lung - virology | Macrophages - virology | Interferon-alpha - genetics | Interferon-beta - genetics | Receptor, Interferon alpha-beta - genetics | Herpesviridae Infections - genetics | Interferon-gamma - genetics | Antigens, Differentiation, Myelomonocytic - immunology | Macrophages - immunology | Interferon Regulatory Factor-3 - immunology | Gammaherpesvirinae - growth & development | Signal Transduction | Interferon Regulatory Factor-1 - immunology | Mice, Inbred C57BL | Gene Expression Regulation | Interferon Regulatory Factor-7 - immunology | Herpesviridae Infections - virology | Interferon-Induced Helicase, IFIH1 - immunology | Antigens, Differentiation, Myelomonocytic - genetics | Proteins - immunology | Interferon Regulatory Factor-1 - genetics | Interferon-alpha - immunology | Mice, Knockout | Host-Pathogen Interactions | Proteins - genetics | Animals | Antigens, Nuclear - genetics | Receptor, Interferon alpha-beta - immunology | Interferon-gamma - immunology | Survival Analysis | Mice | Primary Cell Culture | Antigens, Nuclear - immunology | Lung - immunology | Herpesviridae Infections - immunology | Index Medicus
Journal Article
Cytokine & growth factor reviews, ISSN 1359-6101, 04/2015, Volume 26, Issue 2, pp. 103 - 111
Abstract Interferons (IFN) are key cytokines with multifaceted antiviral and cell-modulatory properties... 
Advanced Basic Science | Interferon types I–III | Interferon–interferon interactions | Interferon genes and receptors | Anti-interferon strategies | Interferon types I-III | Interferon-interferon interactions | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Proliferation | Virus Diseases - immunology | Signal Transduction | Antiviral Agents - immunology | Humans | Transcriptional Activation | Interferon-gamma - physiology | Receptor, Interferon alpha-beta - physiology | Virus Diseases - virology | Interferon Type I - immunology | Interferons - immunology | Genetic Variation | Interferon Type I - genetics | Cell Differentiation | Interferon Type I - physiology | Interferons - physiology | Interferons - genetics | Virus diseases | Interferon | Biological response modifiers | Health aspects | Genetic polymorphisms | IRF, interferon regulatory factor | WNV, West Nile virus | ADAR1, adenosine deaminase acting on RNA 1 | CREB-binding protein | IPS-1, interferon promoter-stimulating factor 1 | EM, environmental mycobacteria | HSE, herpes simplex encephalitis | NEMO, nuclear factor (NF)-kB essential modulator | hCMV, human Cytomegalovirus | APCs, antigen presenting cells | NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells | IRAK-4, interleukin-1 receptor-associated kinase 4 | ds, double strand | SARS, severe acute respiratory syndrome | GAS, gamma interferon activation site | ss, single strand | IFI16, gamma-interferon-inducible protein 16 | TREX1, three prime repair exonuclease 1 | Th, lymphocytes T helper | p300 | PKR, dsRNA-dependent protein kinase | TYK2, tyrosine kinase 2 | IL, interleukin | CRF2, class II cytokine receptor family | IFNGR, interferon gamma receptor | ISGF3, interferon-stimulated gene factor 3 | CHIKV, Chickungunya virus | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | HCV, hepatitis C virus | ATF6, activating transcription factor 6 | EAE, experimental allergic encephalomyelitis | MSMD, Mendelian susceptibility to mycobacterial disease | MxA, Myxovirus Resistance Gene A | RIG-1, retinoic-acid-inducible gene 1 | CBP, chromatin remodeling associated p300 | AP-1, activator protein 1 | OAS, 2′,5′-oligo adenylate synthetase A | HSV-1, herpes simplex virus-1 | SAMHD1, SAM domain and HD domain-containing protein 1 | SARS-CoV, severe acute respiratory syndrome-associated coronavirus | STAT, Signal Transducer and Activator of Transcription | VZV, Varicella-Zoster virus | IFN, interferon | VSV, vesicular stomatitis virus | LASV, Lassa virus | cGAS, cyclic GMP-AMP synthase | ISRE, interferon stimulated response element | EMCV, encephalomyocarditis virus | IFNAR, interferon alpha receptor | BCG, bacille Calmette–Guérin | MHC, major histocompatibility complex | MS, multiple sclerosis | SNPs, single nucleotide polymorphisms | PD-L1, programmed death ligand 1 | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | MAPK, mitogen-activated protein kinases | NK, natural killer cells | PRRs, pattern-recognition receptors
Journal Article
PLoS pathogens, ISSN 1553-7374, 04/2014, Volume 10, Issue 4, pp. e1003989 - e1003989
.... In this study, using murine bone marrow-derived dendritic cells, we assessed type I interferon (IFN... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Dendritic Cells - immunology | Lysosomes - genetics | Immunity, Innate - genetics | Vaccinia virus - genetics | Viral Proteins - metabolism | Endosomes - metabolism | Bone Marrow Cells - virology | Phosphorylation - genetics | Bone Marrow Cells - immunology | Interferon-beta - genetics | Phosphorylation - immunology | Receptor, Interferon alpha-beta - genetics | Nucleotidyltransferases - metabolism | Vaccinia - metabolism | Protein-Serine-Threonine Kinases - metabolism | Receptor, Interferon alpha-beta - metabolism | Endosomes - genetics | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | Viral Proteins - genetics | Mice, Knockout | Interferon-beta - metabolism | Receptor, Interferon alpha-beta - immunology | Vaccinia - immunology | Virulence Factors - metabolism | Mice | Lysosomes - immunology | RNA-Binding Proteins - metabolism | Endosomes - immunology | RNA-Binding Proteins - genetics | Interferon-beta - immunology | Virulence Factors - genetics | Viral Proteins - immunology | Virulence Factors - immunology | Interferon Regulatory Factor-3 - genetics | Vaccinia virus - immunology | Lysosomes - metabolism | Female | Membrane Proteins - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Interferon Regulatory Factor-3 - immunology | Vaccinia virus - metabolism | Protein-Serine-Threonine Kinases - genetics | Membrane Proteins - immunology | Vaccinia - genetics | Animals | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein-Serine-Threonine Kinases - immunology | Nucleotidyltransferases - immunology | Bone Marrow Cells - metabolism | Microbiological research | Dendritic cells | Genetic research | Genetic aspects | Research | Nucleotide sequencing | Vaccinia | Health aspects | DNA sequencing | Index Medicus | Proteins | Studies | Smallpox | Transcription factors | Genes | Deoxyribonucleic acid | DNA | Infections | Genomes | Vaccines | Viral infections | Immune system
Journal Article
Arthritis & rheumatology (Hoboken, N.J.), ISSN 2326-5191, 03/2014, Volume 66, Issue 3, pp. 714 - 725
Journal Article