1992, Frontiers in pharmacology & therapeutics, ISBN 0632030429, ix, 246
Book
Circulation, ISSN 0009-7322, 09/2012, Volume 126, Issue 10, pp. 1256 - 1266
Background-CD4+CD25+Foxp3+ regulatory T cells (Tregs) attenuate atherosclerosis, but their therapeutic application by adoptive transfer is limited by the need...
atherosclerosis | inflammation | cytokines | CARDIAC & CARDIOVASCULAR SYSTEMS | DENDRITIC CELLS | SUBSETS | E KNOCKOUT MICE | LESIONS | AGGRAVATES ATHEROSCLEROSIS | SMOOTH-MUSCLE | INTERFERON-GAMMA | MEDIATED SUPPRESSION | PERIPHERAL VASCULAR DISEASE | IN-VIVO EXPANSION | HEMATOLOGY | E-DEFICIENT MICE | T-Lymphocytes, Regulatory - metabolism | Dose-Response Relationship, Immunologic | Antigen-Antibody Complex - pharmacology | Male | T-Lymphocytes, Regulatory - immunology | Antibodies, Neutralizing - immunology | Interleukin-2 - immunology | Cell Division - immunology | Dietary Fats - pharmacology | Forkhead Transcription Factors - metabolism | Mice, Mutant Strains | Antibodies, Monoclonal - immunology | Disease Models, Animal | Biomarkers - metabolism | Atherosclerosis - drug therapy | Atherosclerosis - immunology | Antibodies, Monoclonal - pharmacology | Antibodies, Neutralizing - pharmacology | Cell Division - drug effects | Disease Progression | T-Lymphocytes, Regulatory - drug effects | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Apolipoproteins E - genetics | Interleukin-2 - pharmacology | Mice | Antigen-Antibody Complex - immunology | CD4 Antigens - metabolism | Development and progression | Interleukin-2 | Research | T cells | Analysis | Atherosclerosis
atherosclerosis | inflammation | cytokines | CARDIAC & CARDIOVASCULAR SYSTEMS | DENDRITIC CELLS | SUBSETS | E KNOCKOUT MICE | LESIONS | AGGRAVATES ATHEROSCLEROSIS | SMOOTH-MUSCLE | INTERFERON-GAMMA | MEDIATED SUPPRESSION | PERIPHERAL VASCULAR DISEASE | IN-VIVO EXPANSION | HEMATOLOGY | E-DEFICIENT MICE | T-Lymphocytes, Regulatory - metabolism | Dose-Response Relationship, Immunologic | Antigen-Antibody Complex - pharmacology | Male | T-Lymphocytes, Regulatory - immunology | Antibodies, Neutralizing - immunology | Interleukin-2 - immunology | Cell Division - immunology | Dietary Fats - pharmacology | Forkhead Transcription Factors - metabolism | Mice, Mutant Strains | Antibodies, Monoclonal - immunology | Disease Models, Animal | Biomarkers - metabolism | Atherosclerosis - drug therapy | Atherosclerosis - immunology | Antibodies, Monoclonal - pharmacology | Antibodies, Neutralizing - pharmacology | Cell Division - drug effects | Disease Progression | T-Lymphocytes, Regulatory - drug effects | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Apolipoproteins E - genetics | Interleukin-2 - pharmacology | Mice | Antigen-Antibody Complex - immunology | CD4 Antigens - metabolism | Development and progression | Interleukin-2 | Research | T cells | Analysis | Atherosclerosis
Journal Article
Annual Review of Immunology, ISSN 0732-0582, 2008, Volume 26, Issue 1, pp. 453 - 479
Much data support an essential role for interleukin (IL)-2 in immune tolerance. This idea is much different from the early paradigm in which IL-2 is central...
T regulatory cell | IL-2 | T effector cell | Immune tolerance | Immune memory | RESPONSES IN-VIVO | FOXP3 EXPRESSION | TGF-BETA | immune memory | TRANSCRIPTIONAL REPRESSOR BLIMP-1 | IMMUNOLOGY | CUTTING EDGE | immune tolerance | REGULATORY T-CELLS | RECEPTOR-ALPHA-CHAIN | IMMUNOLOGICAL SELF-TOLERANCE | HIGH-DOSE INTERLEUKIN-2 | IL-2 RECEPTOR | Receptors, Interleukin-2 - antagonists & inhibitors | Humans | Interleukin-2 - therapeutic use | Interleukin-2 - antagonists & inhibitors | Immunologic Memory - physiology | Autoimmunity - physiology | Immunity - physiology | Interleukin-2 - physiology | Animals | Immunotherapy | T-Lymphocytes, Regulatory - cytology | Receptors, Interleukin-2 - physiology | Receptors, Interleukin-2 - agonists | T-Lymphocytes, Regulatory - physiology
T regulatory cell | IL-2 | T effector cell | Immune tolerance | Immune memory | RESPONSES IN-VIVO | FOXP3 EXPRESSION | TGF-BETA | immune memory | TRANSCRIPTIONAL REPRESSOR BLIMP-1 | IMMUNOLOGY | CUTTING EDGE | immune tolerance | REGULATORY T-CELLS | RECEPTOR-ALPHA-CHAIN | IMMUNOLOGICAL SELF-TOLERANCE | HIGH-DOSE INTERLEUKIN-2 | IL-2 RECEPTOR | Receptors, Interleukin-2 - antagonists & inhibitors | Humans | Interleukin-2 - therapeutic use | Interleukin-2 - antagonists & inhibitors | Immunologic Memory - physiology | Autoimmunity - physiology | Immunity - physiology | Interleukin-2 - physiology | Animals | Immunotherapy | T-Lymphocytes, Regulatory - cytology | Receptors, Interleukin-2 - physiology | Receptors, Interleukin-2 - agonists | T-Lymphocytes, Regulatory - physiology
Journal Article
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Full Text
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4 + CD25 + regulatory T cells
Nature Medicine, ISSN 1078-8956, 11/2005, Volume 11, Issue 11, pp. 1238 - 1243
CD4+CD25+ regulatory T (Treg) cells have a crucial role in maintaining immune tolerance. Mice and humans born lacking Treg cells develop severe autoimmune...
MEDICINE, RESEARCH & EXPERIMENTAL | TOLERANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELF | FOXP3 | TUMOR-IMMUNITY | HIV-INFECTED PATIENTS | TRANSPLANTATION | CELL BIOLOGY | AUTOIMMUNITY | EXPANSION | MICE | RECONSTITUTION | Recombinant Proteins - therapeutic use | Sarcoma - complications | Humans | Middle Aged | Interleukin-2 - therapeutic use | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Interleukin-2 - immunology | Interleukin-2 - administration & dosage | Adult | Female | Lymphocyte Transfusion | Child | Mice, Inbred C57BL | Homeostasis - immunology | Receptors, Interleukin-2 - metabolism | Sarcoma - drug therapy | Receptors, Interleukin-2 - immunology | Mice, Knockout | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphopenia - drug therapy | Adolescent | Forkhead Transcription Factors - analysis | Lymphopenia - immunology | Mice | CD4-Positive T-Lymphocytes - drug effects | Lymphopenia - chemically induced
MEDICINE, RESEARCH & EXPERIMENTAL | TOLERANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELF | FOXP3 | TUMOR-IMMUNITY | HIV-INFECTED PATIENTS | TRANSPLANTATION | CELL BIOLOGY | AUTOIMMUNITY | EXPANSION | MICE | RECONSTITUTION | Recombinant Proteins - therapeutic use | Sarcoma - complications | Humans | Middle Aged | Interleukin-2 - therapeutic use | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Interleukin-2 - immunology | Interleukin-2 - administration & dosage | Adult | Female | Lymphocyte Transfusion | Child | Mice, Inbred C57BL | Homeostasis - immunology | Receptors, Interleukin-2 - metabolism | Sarcoma - drug therapy | Receptors, Interleukin-2 - immunology | Mice, Knockout | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphopenia - drug therapy | Adolescent | Forkhead Transcription Factors - analysis | Lymphopenia - immunology | Mice | CD4-Positive T-Lymphocytes - drug effects | Lymphopenia - chemically induced
Journal Article
Nature, ISSN 0028-0836, 04/2012, Volume 484, Issue 7395, pp. 529 - 533
The immunostimulatory cytokine interleukin-2 (IL-2) is a growth factor for a wide range of leukocytes, including T cells and natural killer (NK) cells(1-3)....
MOLECULAR SIMULATION | ALPHA-RECEPTOR | CLONING | MULTIDISCIPLINARY SCIENCES | SELECTIVE STIMULATION | COMPLEXES | GAMMA(C)-RECEPTOR | IL-2 RECEPTOR | YEAST SURFACE DISPLAY | EXPRESSION | SOFTWARE | Physiological aspects | Interleukin-2 | Tissue engineering | Methods | Phosphorylation | Yeast | Mutation | Engineers | Cytokines | CHEM | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
MOLECULAR SIMULATION | ALPHA-RECEPTOR | CLONING | MULTIDISCIPLINARY SCIENCES | SELECTIVE STIMULATION | COMPLEXES | GAMMA(C)-RECEPTOR | IL-2 RECEPTOR | YEAST SURFACE DISPLAY | EXPRESSION | SOFTWARE | Physiological aspects | Interleukin-2 | Tissue engineering | Methods | Phosphorylation | Yeast | Mutation | Engineers | Cytokines | CHEM | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Journal Article
Trends in Immunology, ISSN 1471-4906, 2015, Volume 36, Issue 12, pp. 763 - 777
Interleukin-2 (IL-2) exerts crucial functions during immune homeostasis via its effects on regulatory T (Treg) cells, and the optimizing and fine-tuning of...
Allergy and Immunology | IMMUNE-COMPLEXES | IL-2/ANTI-IL-2 MAB COMPLEXES | REGULATORY T-CELLS | LOW-DOSE INTERLEUKIN-2 | IN-VIVO EXPANSION | MONOCLONAL-ANTIBODY | INNATE LYMPHOID-CELLS | RECOMBINANT INTERLEUKIN-2 | IMMUNOLOGY | ACTIVATED B-CELLS | CUTTING EDGE | Molecular Sequence Data | Amino Acid Sequence | Animals | Interleukin-2 - immunology | Humans | T-Lymphocytes, Regulatory - immunology | Interleukins | Immunotherapy | Studies | Antigens | Cytokines | Lymphocytes | Cytotoxicity | T cell receptors | Biology | Kinases
Allergy and Immunology | IMMUNE-COMPLEXES | IL-2/ANTI-IL-2 MAB COMPLEXES | REGULATORY T-CELLS | LOW-DOSE INTERLEUKIN-2 | IN-VIVO EXPANSION | MONOCLONAL-ANTIBODY | INNATE LYMPHOID-CELLS | RECOMBINANT INTERLEUKIN-2 | IMMUNOLOGY | ACTIVATED B-CELLS | CUTTING EDGE | Molecular Sequence Data | Amino Acid Sequence | Animals | Interleukin-2 - immunology | Humans | T-Lymphocytes, Regulatory - immunology | Interleukins | Immunotherapy | Studies | Antigens | Cytokines | Lymphocytes | Cytotoxicity | T cell receptors | Biology | Kinases
Journal Article
Clinical Endocrinology, ISSN 0300-0664, 04/2007, Volume 66, Issue 4, pp. 508 - 512
Summary Objective A small number of immune response genes have been consistently associated with the common autoimmune conditions. Recently, a linkage...
LINKAGE DISEQUILIBRIUM | REPLICATION | DEFECTIVE SUPPRESSOR FUNCTION | ENDOCRINOLOGY & METABOLISM | REGULATORY T-CELLS | MECHANISMS | AUTOIMMUNE-DISEASE | LOCUS | AGE | Genetic Predisposition to Disease | Gene Frequency | Humans | Middle Aged | Diabetes Mellitus, Type 1 - genetics | Genotype | Logistic Models | Male | United Kingdom | Genetic Markers | Case-Control Studies | Graves Disease - genetics | Interleukin-2 Receptor alpha Subunit - genetics | Health Surveys | Female | Polymorphism, Single Nucleotide | Odds Ratio | Sequence Tagged Sites | Genetic research | Research institutes
LINKAGE DISEQUILIBRIUM | REPLICATION | DEFECTIVE SUPPRESSOR FUNCTION | ENDOCRINOLOGY & METABOLISM | REGULATORY T-CELLS | MECHANISMS | AUTOIMMUNE-DISEASE | LOCUS | AGE | Genetic Predisposition to Disease | Gene Frequency | Humans | Middle Aged | Diabetes Mellitus, Type 1 - genetics | Genotype | Logistic Models | Male | United Kingdom | Genetic Markers | Case-Control Studies | Graves Disease - genetics | Interleukin-2 Receptor alpha Subunit - genetics | Health Surveys | Female | Polymorphism, Single Nucleotide | Odds Ratio | Sequence Tagged Sites | Genetic research | Research institutes
Journal Article
Journal of Affective Disorders, ISSN 0165-0327, 2011, Volume 139, Issue 3, pp. 230 - 239
Abstract Background Many studies have explored the association between soluble interleukin-2 receptor (sIL-2R), cytokines and major depressive disorder (MDD)....
Psychiatry | Meta-regression | Depression | Inflammation | Cytokine | Meta-analysis | PSYCHIATRY | MARKERS | IL-6 | CLINICAL NEUROLOGY | TRANSFERRIN RECEPTOR | PLASMA-LEVELS | IMMUNE ACTIVATION | INFLAMMATORY RESPONSE | REUPTAKE INHIBITOR THERAPY | HPA-AXIS | BRAIN | Depressive Disorder, Major - blood | Humans | Middle Aged | Receptors, Interleukin-2 - blood | Logistic Models | Male | Depressive Disorder, Major - immunology | Tumor Necrosis Factor-alpha - analysis | Young Adult | Interleukin-6 - blood | Adolescent | Adult | Female | Aged | Child | Cytokines - blood | Receptors, Interleukin-2 - analysis
Psychiatry | Meta-regression | Depression | Inflammation | Cytokine | Meta-analysis | PSYCHIATRY | MARKERS | IL-6 | CLINICAL NEUROLOGY | TRANSFERRIN RECEPTOR | PLASMA-LEVELS | IMMUNE ACTIVATION | INFLAMMATORY RESPONSE | REUPTAKE INHIBITOR THERAPY | HPA-AXIS | BRAIN | Depressive Disorder, Major - blood | Humans | Middle Aged | Receptors, Interleukin-2 - blood | Logistic Models | Male | Depressive Disorder, Major - immunology | Tumor Necrosis Factor-alpha - analysis | Young Adult | Interleukin-6 - blood | Adolescent | Adult | Female | Aged | Child | Cytokines - blood | Receptors, Interleukin-2 - analysis
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 03/2007, Volume 204, Issue 3, pp. 547 - 557
The common.. chain cytokines interleukin (IL)-2 and IL-7 are important regulators of T cell homeostasis. Although IL-2 is implicated in the acute phase of the...
SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | SECONDARY EXPANSION | LYMPHOID HOMEOSTASIS | CD8-T-CELL MEMORY | CLONAL EXPANSION | CD4-T-CELL HELP | RECEPTOR | IL-2 | MICE | IMMUNOLOGY | EXPRESSION | Adjuvants, Immunologic - physiology | Gene Expression Regulation - immunology | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Interleukin-2 Receptor alpha Subunit - biosynthesis | Homeostasis - immunology | Mice, Transgenic | Mice, Knockout | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - genetics | Cell Differentiation - immunology | Interleukin-2 - physiology | Receptors, Interleukin-7 - genetics | Animals | Interleukin-2 Receptor alpha Subunit - genetics | Mice | Mice, Inbred BALB C | Receptors, Interleukin-7 - biosynthesis | Homeostasis - genetics | Immunologic Memory - genetics
SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | SECONDARY EXPANSION | LYMPHOID HOMEOSTASIS | CD8-T-CELL MEMORY | CLONAL EXPANSION | CD4-T-CELL HELP | RECEPTOR | IL-2 | MICE | IMMUNOLOGY | EXPRESSION | Adjuvants, Immunologic - physiology | Gene Expression Regulation - immunology | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Interleukin-2 Receptor alpha Subunit - biosynthesis | Homeostasis - immunology | Mice, Transgenic | Mice, Knockout | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - genetics | Cell Differentiation - immunology | Interleukin-2 - physiology | Receptors, Interleukin-7 - genetics | Animals | Interleukin-2 Receptor alpha Subunit - genetics | Mice | Mice, Inbred BALB C | Receptors, Interleukin-7 - biosynthesis | Homeostasis - genetics | Immunologic Memory - genetics
Journal Article
Immunity, ISSN 1074-7613, 01/2013, Volume 38, Issue 1, pp. 13 - 25
Interleukin-2 (IL-2) is a pleiotropic cytokine produced after antigen activation that plays pivotal roles in the immune response. Discovered as a T cell growth...
BETA-CHAIN | SEVERE COMBINED IMMUNODEFICIENCY | CYTOKINE RECEPTOR | IN-VIVO | REGULATORY T-CELLS | GENE-EXPRESSION | RECEPTOR-ALPHA-CHAIN | MONOCLONAL-ANTIBODY | IMMUNOLOGY | IL-2 RECEPTOR | GAMMA-CHAIN | T-Lymphocyte Subsets - immunology | Humans | X-Linked Combined Immunodeficiency Diseases - genetics | Interleukin Receptor Common gamma Subunit - metabolism | X-Linked Combined Immunodeficiency Diseases - immunology | Interleukin Receptor Common gamma Subunit - immunology | Leukemia-Lymphoma, Adult T-Cell - immunology | T-Lymphocytes, Regulatory - immunology | Receptors, Interleukin-2 - genetics | Interleukin-2 - physiology | T-Lymphocytes, Helper-Inducer - immunology | Immunotherapy | T-Lymphocytes, Helper-Inducer - cytology | CD8-Positive T-Lymphocytes - metabolism | Leukemia-Lymphoma, Adult T-Cell - therapy | Interleukin-2 - metabolism | Leukemia-Lymphoma, Adult T-Cell - genetics | Immune Tolerance | Receptors, Interleukin-2 - metabolism | X-Linked Combined Immunodeficiency Diseases - therapy | Interleukin Receptor Common gamma Subunit - genetics | Cell Differentiation - immunology | Animals | T-Lymphocyte Subsets - metabolism | Interleukin-15 - metabolism | Immunologic Memory | CD8-Positive T-Lymphocytes - immunology | Interleukins | T cells | Cell growth | T cell receptors | Cytokines | Kinases | Immune system
BETA-CHAIN | SEVERE COMBINED IMMUNODEFICIENCY | CYTOKINE RECEPTOR | IN-VIVO | REGULATORY T-CELLS | GENE-EXPRESSION | RECEPTOR-ALPHA-CHAIN | MONOCLONAL-ANTIBODY | IMMUNOLOGY | IL-2 RECEPTOR | GAMMA-CHAIN | T-Lymphocyte Subsets - immunology | Humans | X-Linked Combined Immunodeficiency Diseases - genetics | Interleukin Receptor Common gamma Subunit - metabolism | X-Linked Combined Immunodeficiency Diseases - immunology | Interleukin Receptor Common gamma Subunit - immunology | Leukemia-Lymphoma, Adult T-Cell - immunology | T-Lymphocytes, Regulatory - immunology | Receptors, Interleukin-2 - genetics | Interleukin-2 - physiology | T-Lymphocytes, Helper-Inducer - immunology | Immunotherapy | T-Lymphocytes, Helper-Inducer - cytology | CD8-Positive T-Lymphocytes - metabolism | Leukemia-Lymphoma, Adult T-Cell - therapy | Interleukin-2 - metabolism | Leukemia-Lymphoma, Adult T-Cell - genetics | Immune Tolerance | Receptors, Interleukin-2 - metabolism | X-Linked Combined Immunodeficiency Diseases - therapy | Interleukin Receptor Common gamma Subunit - genetics | Cell Differentiation - immunology | Animals | T-Lymphocyte Subsets - metabolism | Interleukin-15 - metabolism | Immunologic Memory | CD8-Positive T-Lymphocytes - immunology | Interleukins | T cells | Cell growth | T cell receptors | Cytokines | Kinases | Immune system
Journal Article
Blood, ISSN 0006-4971, 07/2006, Volume 108, Issue 1, pp. 390 - 399
CD4(+)CD25(+) regulatory T (Treg) cells control immunologic tolerance and antitumor immune responses. Therefore, in vivo modification of Treg function by...
RAPAMYCIN | CYCLOSPORINE-A | DENDRITIC CELLS | TOLERANCE INDUCTION | BONE-MARROW-TRANSPLANTATION | SUPPRESSOR FUNCTION | IL-2 | IMMUNOSUPPRESSIVE DRUGS | HEMATOLOGY | VERSUS-HOST-DISEASE | MYCOPHENOLATE-MOFETIL | Species Specificity | Mice, Inbred C57BL | Interleukin-2 Receptor alpha Subunit - biosynthesis | Survival Rate | Structure-Activity Relationship | T-Lymphocytes, Regulatory - immunology | Calcineurin - physiology | Dose-Response Relationship, Drug | T-Lymphocytes, Regulatory - drug effects | Animals | Mice, Mutant Strains | Calcineurin - pharmacology | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | CD4 Antigens - biosynthesis | Interleukin-2 - biosynthesis | Transplantation
RAPAMYCIN | CYCLOSPORINE-A | DENDRITIC CELLS | TOLERANCE INDUCTION | BONE-MARROW-TRANSPLANTATION | SUPPRESSOR FUNCTION | IL-2 | IMMUNOSUPPRESSIVE DRUGS | HEMATOLOGY | VERSUS-HOST-DISEASE | MYCOPHENOLATE-MOFETIL | Species Specificity | Mice, Inbred C57BL | Interleukin-2 Receptor alpha Subunit - biosynthesis | Survival Rate | Structure-Activity Relationship | T-Lymphocytes, Regulatory - immunology | Calcineurin - physiology | Dose-Response Relationship, Drug | T-Lymphocytes, Regulatory - drug effects | Animals | Mice, Mutant Strains | Calcineurin - pharmacology | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | CD4 Antigens - biosynthesis | Interleukin-2 - biosynthesis | Transplantation
Journal Article
Journal of immunology (Baltimore, Md, ISSN 0022-1767, 2002, Volume 169, Issue 9, pp. 4850 - 4860
We show that the lymphoid hyperplasia observed in IL-2Ralpha- and IL-2-deficient mice is due to the lack of a population of regulatory cells essential for CD4...
GROWTH-FACTOR-BETA | INFLAMMATORY-BOWEL-DISEASE | EFFECTOR FUNCTION | IN-VIVO | IMMUNOREGULATORY CELLS | IMMUNOLOGICAL SELF-TOLERANCE | MICE | IMMUNOLOGY | AUTOIMMUNE-DISEASE | ANTIGEN RECEPTOR | LYMPHOCYTES-T | T-Lymphocyte Subsets - immunology | Interphase - immunology | Lymphopenia - pathology | CD4-Positive T-Lymphocytes - immunology | Lymphopenia - mortality | Receptors, Interleukin-2 - genetics | Interleukin-2 - physiology | Receptors, Interleukin-2 - deficiency | Bone Marrow Transplantation | Radiation Chimera - immunology | Adjuvants, Immunologic - physiology | Radiation Chimera - genetics | Receptors, Interleukin-2 - biosynthesis | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Homeostasis - immunology | T-Lymphocyte Subsets - transplantation | Mice, Knockout | Interleukin-2 - genetics | Animals | CD4-Positive T-Lymphocytes - transplantation | T-Lymphocyte Subsets - metabolism | Interleukin-2 - deficiency | Survival Analysis | Lymphocyte Count | Lymphopenia - immunology | Mice | Receptors, Interleukin-2 - physiology | Interphase - genetics | Lymphopenia - genetics | Homeostasis - genetics | T-Lymphocyte Subsets | Interleukin-2 | Adjuvants, Immunologic | Interphase | Homeostasis | Radiation Chimera | Life Sciences | Immunology | Lymphopenia | CD4-Positive T-Lymphocytes | Receptors, Interleukin-2
GROWTH-FACTOR-BETA | INFLAMMATORY-BOWEL-DISEASE | EFFECTOR FUNCTION | IN-VIVO | IMMUNOREGULATORY CELLS | IMMUNOLOGICAL SELF-TOLERANCE | MICE | IMMUNOLOGY | AUTOIMMUNE-DISEASE | ANTIGEN RECEPTOR | LYMPHOCYTES-T | T-Lymphocyte Subsets - immunology | Interphase - immunology | Lymphopenia - pathology | CD4-Positive T-Lymphocytes - immunology | Lymphopenia - mortality | Receptors, Interleukin-2 - genetics | Interleukin-2 - physiology | Receptors, Interleukin-2 - deficiency | Bone Marrow Transplantation | Radiation Chimera - immunology | Adjuvants, Immunologic - physiology | Radiation Chimera - genetics | Receptors, Interleukin-2 - biosynthesis | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Homeostasis - immunology | T-Lymphocyte Subsets - transplantation | Mice, Knockout | Interleukin-2 - genetics | Animals | CD4-Positive T-Lymphocytes - transplantation | T-Lymphocyte Subsets - metabolism | Interleukin-2 - deficiency | Survival Analysis | Lymphocyte Count | Lymphopenia - immunology | Mice | Receptors, Interleukin-2 - physiology | Interphase - genetics | Lymphopenia - genetics | Homeostasis - genetics | T-Lymphocyte Subsets | Interleukin-2 | Adjuvants, Immunologic | Interphase | Homeostasis | Radiation Chimera | Life Sciences | Immunology | Lymphopenia | CD4-Positive T-Lymphocytes | Receptors, Interleukin-2
Journal Article