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1. Full Text Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: A meta-analysis and meta-regression
by Liu, Yang and Ho, Roger Chun-Man and Mak, Anselm
Journal of Affective Disorders, ISSN 0165-0327, 2011, Volume 139, Issue 3, pp. 230 - 239
Abstract Background Many studies have explored the association between soluble interleukin-2 receptor (sIL-2R), cytokines and major depressive disorder (MDD).... 
Psychiatry | Meta-regression | Depression | Inflammation | Cytokine | Meta-analysis | PSYCHIATRY | MARKERS | IL-6 | CLINICAL NEUROLOGY | TRANSFERRIN RECEPTOR | PLASMA-LEVELS | IMMUNE ACTIVATION | INFLAMMATORY RESPONSE | REUPTAKE INHIBITOR THERAPY | HPA-AXIS | BRAIN | Depressive Disorder, Major - blood | Humans | Middle Aged | Receptors, Interleukin-2 - blood | Logistic Models | Male | Depressive Disorder, Major - immunology | Tumor Necrosis Factor-alpha - analysis | Young Adult | Interleukin-6 - blood | Adolescent | Adult | Female | Aged | Child | Cytokines - blood | Receptors, Interleukin-2 - analysis | Index Medicus
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2. Full Text Antitumor Activity of Hu14.18-IL2 in Patients With Relapsed/Refractory Neuroblastoma: A Children's Oncology Group (COG) Phase II Study
by Suzanne Shusterman and Wendy B. London and Stephen D. Gillies and Jacquelyn A. Hank and Stephan D. Voss and Robert C. Seeger and C. Patrick Reynolds and Jennifer Kimball and Mark R. Albertini and Barrett Wagner and Jacek Gan and Jens Eickhoff and Kenneth B. DeSantes and Susan L. Cohn and Toby Hecht and Brian Gadbaw and Ralph A. Reisfeld and John M. Maris and Paul M. Sondel
Journal of Clinical Oncology, ISSN 0732-183X, 11/2010, Volume 28, Issue 33, pp. 4969 - 4975
Purpose The hu14.18-IL2 fusion protein consists of interleukin-2 molecularly linked to a humanized monoclonal antibody that recognizes the GD2... 
COLONY-STIMULATING FACTOR | STAGE-IV NEUROBLASTOMA | REFRACTORY NEUROBLASTOMA | ONCOLOGY | BONE-MARROW-TRANSPLANTATION | CELLULAR CYTOTOXICITY | TARGETED INTERLEUKIN-2 THERAPY | PLUS INTERLEUKIN-2 | HIGH-RISK NEUROBLASTOMA | CANCER GROUP | MONOCLONAL-ANTIBODY CH14.18 | Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage | Interleukin-2 - adverse effects | Humans | Receptors, Interleukin-2 - blood | Antibodies, Monoclonal - adverse effects | Interleukin-2 - therapeutic use | Child, Preschool | Antibodies, Monoclonal - therapeutic use | Infant | Antineoplastic Agents - therapeutic use | Neuroblastoma - mortality | Antibodies, Monoclonal - blood | Interleukin-2 - immunology | Neuroblastoma - drug therapy | Adolescent | Lymphocyte Count | Adult | Child | Antibodies, Monoclonal - immunology | Interleukin-2 - blood | Index Medicus | Pedi10 | Original Reports | To6 | To23
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3. Full Text A meta-analysis of blood cytokine network alterations in psychiatric patients: Comparisons between schizophrenia, bipolar disorder and depression
by Goldsmith, D.R and Rapaport, M.H and Miller, B.J
Molecular Psychiatry, ISSN 1359-4184, 12/2016, Volume 21, Issue 12, pp. 1696 - 1709
Schizophrenia, bipolar disorder and major depressive disorder (MDD) have all been associated with aberrant blood cytokine levels; however, neither the pattern... 
PRO-INFLAMMATORY CYTOKINES | PSYCHIATRY | INTERLEUKIN-1 RECEPTOR ANTAGONIST | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-MEDIATED-IMMUNITY | NECROSIS-FACTOR-ALPHA | MAJOR DEPRESSION | NEUROSCIENCES | SOLUBLE INTERLEUKIN-2 | PLASMA-LEVELS | SERUM-LEVELS | 1ST EPISODE PSYCHOSIS | DRUG-NAIVE SCHIZOPHRENIA | Depressive Disorder, Major - blood | Bipolar Disorder - metabolism | Interleukin-6 - analysis | Schizophrenia - metabolism | Schizophrenia - blood | Cytokines - analysis | Depressive Disorder, Major - metabolism | Humans | Receptors, Interleukin-2 - blood | Tumor Necrosis Factor-alpha - blood | Male | Psychotic Disorders - blood | Bipolar Disorder - blood | Interleukin 1 Receptor Antagonist Protein - blood | Tumor Necrosis Factor-alpha - analysis | Psychotic Disorders - metabolism | Depression - metabolism | Interleukin-6 - blood | Adult | Female | Interleukin 1 Receptor Antagonist Protein - analysis | Cytokines - blood | Depression - blood | Receptors, Interleukin-2 - analysis | Care and treatment | Cytokines | Psychiatric disability evaluation | Analysis | Depression, Mental | Schizophrenia | Comparative analysis | Index Medicus
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4. Full Text Endosulfan increases seric interleukin-2 like (IL-2L) factor and immunoglobulin M (IgM) of Nile tilapia ( Oreochromis niloticus) challenged with Aeromona hydrophila
by Tellez-Bañuelos, Martha Cecilia and Santerre, Anne and Casas-Solis, Josefina and Zaitseva, Galina
Fish and Shellfish Immunology, ISSN 1050-4648, 2010, Volume 28, Issue 2, pp. 401 - 405
Endosulfan is a persistent organochlorine insecticide which is extremely toxic to fish. It is known to induce immunological alterations in juvenile Nile... 
Endosulfan | Aeromonas hydrophila | Oreochromis niloticus | Immunoglobulin M, Interleukin-2 like factor | Immunoglobulin M | IMMUNE-RESPONSE | ACTIVATION | RECEPTOR | IMMUNOLOGY | Interleukin-2 like factor | FISHERIES | MARINE & FRESHWATER BIOLOGY | HUMAN HACAT KERATINOCYTES | GROWTH | FISH | VETERINARY SCIENCES | MICE | INFECTION | ANTIBODY-RESPONSE | TROUT ONCORHYNCHUS-MYKISS | Cichlids - immunology | Gram-Negative Bacterial Infections - immunology | Male | Aeromonas hydrophila - immunology | Immunoglobulin M - immunology | Gene Expression Regulation - drug effects | Animals | Immunoglobulin M - blood | Interleukin-2 - immunology | Water Pollutants, Chemical - toxicity | Endosulfan - toxicity | Immunity, Humoral - drug effects | Insecticides - toxicity | Interleukin-2 - blood | Autoimmunity | Insecticides | Interleukins | Fishes | Index Medicus
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5. Full Text Changes in serum interleukin-2, -6, and -8 levels before and during treatment with risperidone and haloperidol: Relationship to outcome in schizophrenia
by Zhang, Xiang Yang and Zhou, Dong Feng and Cao, Lian Yuan and Zhang, Pei Yan and Wu, Gui Ying and Shen, Yu Cun
Journal of Clinical Psychiatry, ISSN 0160-6689, 07/2004, Volume 65, Issue 7, pp. 940 - 947
Background: Many studies have indicated that immune cytokines may be involved in the pathophysiology of schizophrenia. Recently, there have been reports that... 
CLOZAPINE | PLASMA INTERLEUKIN-6 | CYTOKINE PRODUCTION | INTERFERON-GAMMA | INFLAMMATORY RESPONSE SYSTEM | PSYCHIATRY | IL-2 | DRUG-FREE | PSYCHOLOGY, CLINICAL | RECEPTOR ANTAGONIST | CSF LEVELS | PATIENTS RESISTANT | Humans | Male | Immunity, Cellular - drug effects | Interleukin-2 - immunology | Risperidone - therapeutic use | Antipsychotic Agents - therapeutic use | Interleukin-6 - blood | Radioimmunoassay | Adult | Female | Interleukin-8 - blood | Haloperidol - pharmacology | Double-Blind Method | Enzyme-Linked Immunosorbent Assay | Schizophrenia - blood | Risperidone - pharmacology | Haloperidol - therapeutic use | Treatment Outcome | Hospitalization | Schizophrenia - immunology | Interleukin-6 - immunology | Antipsychotic Agents - pharmacology | Schizophrenia - drug therapy | Interleukin-8 - immunology | Interleukin-2 - blood | Index Medicus
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6. Full Text Interleukin-2 receptor and angiotensin-converting enzyme as markers for ocular sarcoidosis
by Gundlach, Enken and Hoffmann, Michael Marcus and Prasse, Antje and Heinzelmann, Sonja and Ness, Thomas
PLoS ONE, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, pp. e0147258 - e0147258
Purpose To study the impact of soluble IL2 receptor (sIL2R), chest x-ray (CxR), and angiotensin-converting enzyme (ACE) as markers for sarcoidosis in uveitis... 
MEDICAL PROGRESS | 1ST INTERNATIONAL WORKSHOP | MULTIDISCIPLINARY SCIENCES | T-CELL-ACTIVATION | UVEITIS | TNF-ALPHA RELEASE | PULMONARY SARCOIDOSIS | RECEPTOR | PARAMETERS | SERUM MARKERS | BRONCHOALVEOLAR LAVAGE | Uveitis - diagnosis | Uveitis - etiology | Sarcoidosis - diagnosis | Humans | Middle Aged | Receptors, Interleukin-2 - blood | Male | Biomarkers - blood | Sarcoidosis - blood | Young Adult | Peptidyl-Dipeptidase A - blood | Adolescent | Aged, 80 and over | Adult | Female | Aged | Radiography, Thoracic | Retrospective Studies | Uveitis - pathology | Sarcoidosis - pathology | Complications and side effects | Care and treatment | Interleukins | Sarcoidosis | Physiological aspects | Development and progression | Research | ACE inhibitors | Chest | Interleukin 2 receptors | Enzymes | Lymphatic system | Disease | Cytokines | Laboratories | Interleukin | Markers | Parameter sensitivity | Patients | Sensitivity | Hospitals | Interleukin 2 | Converting | Computed tomography | Biopsy | Peptidyl-dipeptidase A | Uveitis | Angiotensin | Index Medicus
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7. Full Text Peripheral interleukin-2 level is associated with negative symptoms and cognitive performance in schizophrenia
by Asevedo, Elson and Rizzo, Lucas B and Gadelha, Ary and Mansur, Rodrigo B and Ota, Vanessa K and Berberian, Arthur A and Scarpato, Bruno S and Teixeira, Antônio L and Bressan, Rodrigo A and Brietzke, Elisa
Physiology & Behavior, ISSN 0031-9384, 2014, Volume 129, pp. 194 - 198
Abstract Although several studies have pointed to a possible role of interleukin 2 (IL-2) in schizophrenia (SZ), association between IL-2 and the different... 
Psychiatry | Schizophrenia | Behavioral symptoms | Cognition | Interleukin-2 | Biological markers | WORKING MEMORY | METAANALYSIS | BIPOLAR DISORDER | CYTOKINE ALTERATIONS | IN-VITRO | POLYMORPHISMS | INTERFERON-GAMMA | BEHAVIORAL SCIENCES | FETAL-RAT BRAIN | TNF-ALPHA | PSYCHOLOGY, BIOLOGICAL | RECEPTORS | Blood Chemical Analysis | Schizophrenia - blood | Humans | Male | Schizophrenic Psychology | Intelligence Tests | Learning | Neuropsychological Tests | Psychiatric Status Rating Scales | Language | Adult | Female | Memory, Short-Term | Executive Function | Interleukin-2 - blood | Interleukins | Index Medicus
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8. Full Text IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
by Zorn, Emmanuel and Nelson, Erik A and Mohseni, Mehrdad and Porcheray, Fabrice and Kim, Haesook and Litsa, Despina and Bellucci, Roberto and Raderschall, Elke and Canning, Christine and Soiffer, Robert J and Frank, David A and Ritz, Jerome
Blood, ISSN 0006-4971, 09/2006, Volume 108, Issue 5, pp. 1571 - 1579
IL-2 plays a critical role in the maintenance of CD4(+)CD25(+) FOXP3(+) regulatory T cells (Tregs) in vivo. We examined the effects of IL-2 signaling in human... 
PROLONGED INFUSION | NATURAL-KILLER-CELLS | MELANOMA | BONE-MARROW-TRANSPLANTATION | DOSE RECOMBINANT INTERLEUKIN-2 | TOLERANCE | TRANSCRIPTION FACTOR FOXP3 | RECEPTOR | CONTINUOUS-INFUSION | HEMATOLOGY | VERSUS-HOST-DISEASE | CD4-Positive T-Lymphocytes - cytology | Humans | Receptors, Interleukin-2 - blood | Interleukin-2 - therapeutic use | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Forkhead Transcription Factors - genetics | Neoplasms - drug therapy | CD4-Positive T-Lymphocytes - immunology | Gene Expression Regulation - drug effects | Stem Cell Transplantation | STAT Transcription Factors - physiology | Antigens, CD - blood | Neoplasms - immunology | T-Lymphocytes - drug effects | Cell Division | Interleukin-2 - pharmacology | Killer Cells, Natural - immunology | T-Lymphocytes - immunology | Killer Cells, Natural - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - immunology | CD4-Positive T-Lymphocytes - drug effects | Index Medicus | Abridged Index Medicus | Immunobiology
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9. Full Text In Vivo maintenance of human regulatory T cells during CD25 blockade
by Huss, David J and Mehta, Devangi S and Sharma, Akanksha and You, Xiaojun and Riester, Katherine A and Sheridan, James P and Amaravadi, Lakshmi S and Elkins, Jacob S and Fontenot, Jason D
Journal of Immunology, ISSN 0022-1767, 01/2015, Volume 194, Issue 1, pp. 84 - 92
Regulatory T cells (Tregs) mediate immune tolerance to self and depend on IL-2 for homeostasis. Treg deficiency, dysfunction, and instability are implicated in... 
MYELIN BASIC-PROTEIN | FOXP3 EXPRESSION | ACTIVATION | INSTABILITY | MULTIPLE-SCLEROSIS | NK CELLS | TOLERANCE | STABILITY | DACLIZUMAB | IMMUNOLOGY | LYMPHOCYTES | Cell Cycle - genetics | Phosphorylation | Interleukin-2 Receptor alpha Subunit - antagonists & inhibitors | Self Tolerance - immunology | Humans | Immunosuppressive Agents - therapeutic use | Interleukin-17 - immunology | Interleukin Receptor Common gamma Subunit - immunology | T-Lymphocytes, Regulatory - immunology | STAT5 Transcription Factor - metabolism | Interleukin-2 - immunology | Forkhead Transcription Factors - metabolism | Interleukin-2 Receptor alpha Subunit - immunology | Forkhead Transcription Factors - biosynthesis | Promoter Regions, Genetic | Self Tolerance - drug effects | Antibodies, Monoclonal, Humanized - therapeutic use | Multiple Sclerosis, Relapsing-Remitting - immunology | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Immunoglobulin G - therapeutic use | CD4 Lymphocyte Count | Interleukin-17 - biosynthesis | Forkhead Transcription Factors - genetics | T-Lymphocytes, Regulatory - drug effects | Interferon-gamma - immunology | Cell Cycle - drug effects | Interleukin-2 - biosynthesis | Interleukin-2 Receptor beta Subunit - immunology | Interferon-gamma - biosynthesis | Interleukin-2 - blood | Index Medicus | Abridged Index Medicus
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10. Full Text Serum soluble interleukin‐2 receptor level is more sensitive than angiotensin‐converting enzyme or lysozyme for diagnosis of sarcoidosis and may be a marker of multiple organ involvement
by Thi Hong Nguyen, Chuyen and Kambe, Naotomo and Kishimoto, Izumi and Ueda‐Hayakawa, Ikuko and Okamoto, Hiroyuki
The Journal of Dermatology, ISSN 0385-2407, 07/2017, Volume 44, Issue 7, pp. 789 - 797
Skin lesions in sarcoidosis are often the initial symptoms that enable the dermatologist to be the first to diagnose this granulomatosis. However, diagnosis is... 
angiotensin‐converting enzyme | interleukin‐2 receptor | lymphocyte activation | sarcoidosis | granuloma | interleukin-2 receptor | angiotensin-converting enzyme | DIFFERENTIAL-DIAGNOSIS | ACE | RECEPTOR | CUTANEOUS SARCOIDOSIS | DERMATOLOGY | DISEASE | SIL-2R | SEVERITY | Severity of Illness Index | Sarcoidosis - diagnosis | Follow-Up Studies | Humans | Japan | Middle Aged | Receptors, Interleukin-2 - blood | Male | Biomarkers - blood | Muramidase - blood | Sarcoidosis - blood | Skin Diseases - blood | Peptidyl-Dipeptidase A - blood | Sensitivity and Specificity | Female | Aged | Retrospective Studies | Interleukins | ACE inhibitors | Lysozyme | Angiotensin | Enzymes | Sarcoidosis | Cytokines | Interleukin 2 | Peptidyl-dipeptidase A | Lung diseases | Granulomatosis | Skin diseases | Tuberculin | Diagnosis | Index Medicus
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11. Full Text CD4+CD25high Regulatory Cells in Human Peripheral Blood
by Baecher-Allan, Clare and Brown, Julia A and Freeman, Gordon J and Hafler, David A
The Journal of Immunology, ISSN 0022-1767, 08/2001, Volume 167, Issue 3, pp. 1245 - 1253
Thymectomy in mice on neonatal day 3 leads to the development of multiorgan autoimmune disease due to loss of a CD(+)CD25(+) T cell regulatory population in... 
T-Lymphocyte Subsets - immunology | CD4 Antigens - blood | Coculture Techniques | Humans | Leukocyte Common Antigens - biosynthesis | Interleukin-2 - antagonists & inhibitors | RNA, Messenger - metabolism | CD4-Positive T-Lymphocytes - immunology | Signal Transduction - immunology | B7-1 Antigen | Abatacept | RNA, Messenger - antagonists & inhibitors | Receptors, Antigen, T-Cell - immunology | Membrane Glycoproteins | Immunosuppressive Agents - pharmacology | Receptors, Antigen, T-Cell - metabolism | Receptors, Interleukin-2 - biosynthesis | B7-H1 Antigen | Lymphocyte Activation | Peptides - physiology | Receptors, Interleukin-2 - blood | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Receptors, Antigen, T-Cell - physiology | Antigens, Differentiation - physiology | CTLA-4 Antigen | Interleukin-2 - genetics | Immunoconjugates | Blood Proteins | T-Lymphocyte Subsets - metabolism | Lymphocyte Count | CD4 Antigens - biosynthesis | HLA-DR Antigens - biosynthesis | Kinetics | Antigens, CD | Index Medicus | Abridged Index Medicus
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