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1. Full Text The protein phosphatase 2A regulatory subunit B56γ mediates suppression of T cell receptor (TCR)-induced nuclear factor-κB (NF-κB) activity
by Breuer, Rebecca and Becker, Michael S and Brechmann, Markus and Mock, Thomas and Arnold, Rüdiger and Krammer, Peter H
Journal of Biological Chemistry, ISSN 0021-9258, 1782, Volume 289, Issue 21, pp. 14996 - 15004
NF-kappa B is an important transcription factor in the immune system, and aberrant NF-kappa B activity contributes to malignant diseases and autoimmunity. In T... 
ACTIVATION | HOMEOSTASIS | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LYMPHOMA | ALPHA | PP2A | IDENTIFICATION | TYROSINE-PHOSPHATASE | OKADAIC ACID | MALT1 | Gene Expression - genetics | I-kappa B Proteins - immunology | Humans | NF-kappa B - immunology | Protein Kinase C-theta | NF-kappa B - metabolism | I-kappa B Proteins - metabolism | Protein Phosphatase 2 - immunology | Isoenzymes - immunology | Signal Transduction - immunology | Lymphocyte Activation - immunology | Interleukin-2 - immunology | I-kappa B Kinase - metabolism | RNA Interference | T-Lymphocytes - metabolism | Isoenzymes - metabolism | Protein Kinase C - metabolism | Gene Expression - immunology | Receptors, Antigen, T-Cell - immunology | Phosphorylation - immunology | Interleukin-2 - metabolism | NF-KappaB Inhibitor alpha | Receptors, Antigen, T-Cell - metabolism | Jurkat Cells | Cells, Cultured | Protein Phosphatase 2 - genetics | Protein Kinase C - immunology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Interleukin-2 - genetics | Protein Phosphatase 2 - metabolism | I-kappa B Kinase - immunology | T-Lymphocytes - immunology | Signaling | Signal Transduction | T Cell | Serine | Nuclear Factor-κB (NF-κB) | NF-κB Transcription Factor | T Cell Receptor | IL-2 | PPP2R5C | Phosphoprotein Phosphatase | B56γ | Threonine Protein Phosphatase
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2. Full Text Imaging Bradykinin B1 Receptor with 68Ga-Labeled [des-Arg10]Kallidin Derivatives: Effect of the Linker on Biodistribution and Tumor Uptake
by Amouroux, Guillaume and Pan, Jinhe and Jenni, Silvia and Zhang, Chengcheng and Zhang, Zhengxing and Hundal-Jabal, Navjit and Colpo, Nadine and Liu, Zhibo and Bénard, François and Lin, Kuo-Shyan
Molecular Pharmaceutics, ISSN 1543-8384, 08/2015, Volume 12, Issue 8, pp. 2879 - 2888
Bradykinin B1 receptor (B1R) that is overexpressed in cancers but minimally expressed in normal healthy tissues represents an attractive biomarker for the... 
linker | gallium-68 | positron emission tomography | bradykinin B1 receptor | antagonist | kallidin | Neoplasms - metabolism | Radiopharmaceuticals - pharmacokinetics | Humans | Peptide Fragments - pharmacokinetics | Contrast Media - pharmacokinetics | Male | Tomography, X-Ray Computed | Positron-Emission Tomography - methods | Mice, SCID | Neoplasms - diagnostic imaging | Mice, Knockout | Tissue Distribution | Kallidin - chemistry | Animals | Image Processing, Computer-Assisted | HEK293 Cells | Kallidin - analogs & derivatives | Gallium Radioisotopes - pharmacokinetics | Mice, Inbred NOD | Mice | Mice, Inbred BALB C | Receptor, Bradykinin B1 - metabolism | Receptors, Interleukin-2 - physiology | Neoplasms - pathology
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3. Full Text Inflammatory Biomarkers and Depression
by Müller, Norbert and Müller, Norbert and Myint, Aye-Mu and Myint, Aye-Mu and Schwarz, Markus J and Schwarz, Markus J
Neurotoxicity Research, ISSN 1029-8428, 2/2011, Volume 19, Issue 2, pp. 308 - 318
Antidepressants, predominantly serotonin- and/or noradrenaline reuptake inhibiting drugs have several shortcomings. The exact pathophysiological mechanisms... 
Neurochemistry | Antidepressant | Neurology | Neurosciences | Biomedicine | Major depression | Neurobiology | Inflammation | Psychoneuroimmunology | Cyclooxygenase-2 | Pharmacology/Toxicology | Cell Biology | C-REACTIVE PROTEIN | MIGRATION INHIBITORY FACTOR | NECROSIS-FACTOR-ALPHA | NEUROSCIENCES | EXCITATORY AMINO-ACIDS | ACUTE-PHASE PROTEINS | NMDA RECEPTOR COMPLEX | DOUBLE-BLIND | OPEN-LABEL TRIAL | PITUITARY-ADRENAL AXIS | Biomarkers - metabolism | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Humans | Depressive Disorder - drug therapy | Inflammation Mediators - therapeutic use | Depressive Disorder - metabolism | Antidepressive Agents - therapeutic use | Animals | Cyclooxygenase 2 Inhibitors - therapeutic use | Inflammation Mediators - metabolism | Antidepressive Agents - adverse effects | Depressive Disorder - psychology | Kynurenine - metabolism
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4. Full Text Neuroimmune Pharmacology of Neurodegenerative and Mental Diseases
by Shie, Feng-Shiun and Shie, Feng-Shiun and Chen, Yun-Hsiang and Chen, Yun-Hsiang and Chen, Chia-Hsiang and Chen, Chia-Hsiang and Ho, Ing-Kang and Ho, Ing-Kang
Journal of Neuroimmune Pharmacology, ISSN 1557-1890, 3/2011, Volume 6, Issue 1, pp. 28 - 40
Neuroimmune pharmacology is a newly emerging field that intersects with neuroscience, immunology, and pharmacology and that is seeking avenues for... 
Neurosciences | Biomedicine | Immunology | Neurodegeneration | Cytokine | Psychiatric diseases | Drugs of abuse | Pharmacology/Toxicology | Glia | NeuroAIDS | Cell Biology | Virology | ALZHEIMERS-DISEASE | NECROSIS-FACTOR-ALPHA | HUMAN-IMMUNODEFICIENCY-VIRUS | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | ANTI-HIV DRUGS | T-CELL PROLIFERATION | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | SOLUBLE CYTOKINE RECEPTORS | PLACEBO-CONTROLLED TRIAL | NF-KAPPA-B | Neuroimmunomodulation - physiology | Mental Disorders - immunology | Neurodegenerative Diseases - immunology | Brain - immunology | Humans | Cytokines - immunology | Drugs and athletes | Nervous system diseases | Neurons | Illegal drugs | Pharmacology | HIV (Viruses) | Health aspects | Mental illness | Cytokines | Mental disorders | Index Medicus
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5. Full Text Signaling through the P38 and ERK pathways: a common link between HIV replication and the immune response
by Furler, Robert L and Uittenbogaart, Christel H
Immunologic Research, ISSN 0257-277X, 12/2010, Volume 48, Issue 1, pp. 99 - 109
One of the defining characteristics of HIV is its ability to manipulate the human immune response to promote its own replication. Since the beginning of the... 
Cytokines | Internal Medicine | IL-2 | Activation | Medicine/Public Health, general | IL-10 | Allergology | Immunosuppression | Immunology | Medicine & Public Health | HIV | P38 | TNF-α | Proinflammatory | ERK | ACTIVATED PROTEIN-KINASE | CD4 T-CELLS | TNF-alpha | MAP KINASE | IL-10 PRODUCTION | IMMUNOLOGY | INDEPENDENT PATHWAY | LONG TERMINAL REPEAT | IMMUNODEFICIENCY-VIRUS TYPE-1 | HIV-1-INFECTED INDIVIDUALS | NF-KAPPA-B | DISEASE PROGRESSION | HIV-1 - pathogenicity | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | HIV Envelope Protein gp120 - metabolism | Extracellular Signal-Regulated MAP Kinases - immunology | CD4-Positive T-Lymphocytes - immunology | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | Signal Transduction - immunology | HIV-1 - physiology | Receptors, HIV - immunology | p38 Mitogen-Activated Protein Kinases - metabolism | Receptors, Cytokine - metabolism | CD4-Positive T-Lymphocytes - virology | Cytokines - immunology | CD4 Antigens - immunology | Cytokines - metabolism | Lymphocyte Activation | CD4-Positive T-Lymphocytes - metabolism | p38 Mitogen-Activated Protein Kinases - immunology | Receptors, HIV - metabolism | Virus Replication | Receptors, Cytokine - immunology | Apoptosis | CD4 Antigens - metabolism | Biomarkers | Signal transduction | Human immunodeficiency virus--HIV | Epidemics | Fas antigen | Immune response | PD-1 protein | CD95 antigen | biomarkers | Chronic infection | Extracellular signal-regulated kinase | Intracellular signalling | MAP kinase | Lymphocytes T | Vaccines | CD4 antigen | FasL protein | Interleukin 2 | Virions | Immunopathogenesis | Interleukin 10 | Replication | Tumor necrosis factor- alpha
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6. Full Text In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3
by Sommer, V.H and Clemmensen, O.J and Nielsen, O and Wasik, M and Lovato, P and Brender, C and Eriksen, K.W and Woetmann, A and Kaestel, C.G and Nissen, M.H and Ropke, C and Skov, S and Ødum, N
Leukemia, ISSN 0887-6924, 2004, Volume 18, Issue 7, pp. 1288 - 1295
A characteristic feature of neoplastic transformation is a perpetual activation of oncogenic proteins. Here, we studied signal transducers and activators of... 
In vivo | Neoplastic transformation | CTCL | STAT3 | Apoptosis | CONSTITUTIVE ACTIVATION | neoplastic transformation | TRANSCRIPTION | apoptosis | MYCOSIS-FUNGOIDES | RECEPTOR | PROLIFERATION | SEZARY-SYNDROME | ONCOLOGY | GROWTH | in vivo | DIFFERENTIATION | HEMATOLOGY | EXPRESSION | Immunohistochemistry | Humans | Middle Aged | Neoplasm Proteins - physiology | Skin Neoplasms - chemistry | Trans-Activators - analysis | DNA-Binding Proteins - analysis | Male | Neoplasm Proteins - metabolism | Trans-Activators - physiology | DNA-Binding Proteins - metabolism | Lymphoma, T-Cell, Cutaneous - etiology | Mycosis Fungoides - pathology | Lymphoma, T-Cell, Cutaneous - chemistry | Neoplasm Invasiveness - pathology | Aged, 80 and over | Adult | Female | Lymphocytes - chemistry | Skin Neoplasms - pathology | DNA-Binding Proteins - physiology | Lymphoma, T-Cell, Cutaneous - pathology | Lymphocytes - pathology | Neoplasm Proteins - analysis | Trans-Activators - metabolism | Aged | STAT3 Transcription Factor | Mycosis Fungoides - chemistry
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7. Full Text Iron and the immune system
by Ward, Roberta J and Ward, Roberta J and Crichton, Robert R and Crichton, Robert R and Taylor, Deanna L and Taylor, Deanna L and Corte, Laura Della and Corte, Laura Della and Srai, Surjit K and Srai, Surjit K and Dexter, David T and Dexter, David T
Journal of Neural Transmission, ISSN 0300-9564, 3/2011, Volume 118, Issue 3, pp. 315 - 328
Iron and immunity are closely linked: firstly by the fact that many of the genes/proteins involved in iron homoeostasis play a vital role in controlling iron... 
Ferroportin | Neurology | Neurosciences | Medicine & Public Health | Iron | Inflammation | Pharmacology/Toxicology | Psychiatry | Hepcidin | Macrophage | MYCOBACTERIUM-TUBERCULOSIS | HOMEOSTASIS | MACROPHAGES | TRANSCRIPTION | NEUROSCIENCES | CLINICAL NEUROLOGY | INTERFERON-GAMMA | TRANSFERRIN | HOST-DEFENSE | LIPOPOLYSACCHARIDE | HEPCIDIN EXPRESSION | HEMOCHROMATOSIS | Microglia - metabolism | Cytokines - metabolism | Humans | Toll-Like Receptors - immunology | Inflammation - immunology | Immunity, Innate | Iron - metabolism | Inflammation - metabolism | Macrophages - metabolism | Microglia - immunology | Immune System - metabolism | Homeostasis - physiology | Immune System - immunology | Toll-Like Receptors - metabolism | Macrophages - immunology | Cytokines - immunology | Proteins | Macrophages | Lymphocytes | Heme
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8. Full Text The contribution of direct TLR signaling to T cell responses
by Rahman, Adeeb H and Taylor, Devon K and Turka, Laurence A
Immunologic Research, ISSN 0257-277X, 10/2009, Volume 45, Issue 1, pp. 25 - 36
It is well established that Toll-like receptors (TLRs) play a critical role in the generation of innate immune responses and thereby also play an important,... 
CD8 T cell | PAMP | Co-stimulation | CD4 T cell | Inflammation | TLR | Clonal expansion | MyD88 | DENDRITIC CELLS | CHORIOMENINGITIS VIRUS-INFECTION | IMMUNOLOGY | CUTTING EDGE | ADAPTIVE IMMUNITY | MESSENGER-RNA | TOLL-LIKE RECEPTORS | TOXOPLASMA-GONDII | GENE INDUCTION-PROGRAM | EXPRESSION | Cell Proliferation | Antigens, CD - biosynthesis | Signal Transduction - immunology | T-Lymphocytes - metabolism | Receptors, Antigen, T-Cell - immunology | Interferon-gamma - genetics | T-Lymphocytes - pathology | Toll-Like Receptors - metabolism | Receptors, Antigen, T-Cell - metabolism | Lymphocyte Activation | Interferon-gamma - secretion | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Immunity, Innate | Mice, Knockout | Interleukin-2 - genetics | Animals | Protein Binding | T-Lymphocytes - immunology | Mice | Interleukin-2 - biosynthesis | Interleukin-2 - secretion | Myeloid Differentiation Factor 88 - metabolism | Interferon-gamma - biosynthesis | Signal transduction | Infections | Immunology | Cellular biology | Cytokines
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9. Full Text The in vitro effects of Bordetella pertussis lymphocytosis-promoting factor on murine lymphocytes. III. B-cell dependence for T-cell proliferation
by Ho, M K and Kong, A S and Morse, S I
The Journal of experimental medicine, ISSN 0022-1007, 05/1979, Volume 149, Issue 5, pp. 1001 - 1017
The nature of the helper lymphocytes in lymphocytosis-promoting factor (LPF)-induced proliferation was explored. Removal of macrophages from adherent... 
Macrophages - physiology | Interleukin-2 | Receptors, Antigen, B-Cell | B-Lymphocytes - physiology | Bordetella pertussis | Lymphokines | Complement System Proteins | Animals | T-Lymphocytes - cytology | Antilymphocyte Serum - pharmacology | Cell Division | Mice, Inbred CBA | Female | Mice | Antibodies, Anti-Idiotypic | Receptors, Drug
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10. Full Text The in vitro effects of Bordetella pertussis lymphocytosis-promoting factor on murine lymphocytes. III. B-cell dependence for T-cell proliferation
by Ho, M. K
Journal of Experimental Medicine, ISSN 0022-1007, 05/1979, Volume 149, Issue 5, pp. 1001 - 1017
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11. Full Text Mechanisms of glucocorticoid-induced immunosuppression: Inhibitory effects on expression of fc receptors and production of T-cell growth factor
by Crabtree, Gerald R and Gillis, Steven and Smith, Kendall A and Munck, Allan
Journal of Steroid Biochemistry, ISSN 0022-4731, 1980, Volume 12, Issue C, pp. 445 - 449
T-cell growth factor, produced by mitogen or antigen-stimulated spleen cells, is necessary for the proliferation of T-lymphocytes in culture, and may be... 
Cell Line | T-Lymphocytes - physiology | Humans | Immunoglobulin Fc Fragments | Cells, Cultured | Rats | Spleen - drug effects | Immunosuppression | Animals | Dexamethasone - pharmacology | T-Lymphocytes - drug effects | Glucocorticoids - pharmacology | DNA - biosynthesis | T-Lymphocytes - immunology | Kinetics | Lymphokines - biosynthesis | Spleen - physiology | Interleukin-2 - biosynthesis | Receptors, Fc - physiology | Thymidine - metabolism
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12. Full Text Rat Dendritic Cells Function as Accessory Cells and Control the Production of a Soluble Factor Required for Mitogenic Responses of T Lymphocytes
by Wolfgang E. F. Klinkert and Jon H. LaBadie and James P. O'Brien and Carl F. Beyer and William E. Bowers
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/1980, Volume 77, Issue 9, pp. 5414 - 5418
Transformation of T lymphocytes, induced by treatment with periodate or with neuraminidase plus galactose oxidase, requires the participation of accessory... 
T lymphocytes | Dendritic cells | Spleen cells | Ungulates | Lymphocytes | Rats | Cultured cells | Transponders | Macrophages | Lymph nodes
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13. Functional studies on receptor complexes of B-lymphocytes involved in regulation of growth and maturation
by Melchers, F and Andersson, J and Lernhardt, W and Schreier, M.H
Biochemical Society Symposia, ISSN 0067-8694, 1980, Volume 45, pp. 75 - 88
Receptors, Immunologic - physiology | Immunoglobulins - immunology | Interphase | Lymphocyte Activation | Cells, Cultured | Receptors, Mitogen - physiology | Animals | B-Lymphocytes - immunology | Histocompatibility Antigens Class II - immunology | Cell Division | Interleukin-2 - pharmacology | Receptors, Antigen, B-Cell - physiology | T-Lymphocytes - immunology | Mice
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14. Full Text Rat dendritic cells function as accessory cells and control the production of a soluble factor required for mitogenic responses of T lymphocytes
by W E Klinkert and J H LaBadie and J P O'Brien and C F Beyer and W E Bowers
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/1980, Volume 77, Issue 9, pp. 5414 - 5418
Transformation of T lymphocytes, induced by treatment with periodate or with neuraminidase plus galactose oxidase, requires the participation of accessory... 
Animals | Receptors, Fc - analysis | T-Lymphocytes - metabolism | Adhesiveness | Leukocytes - classification | Rats | Male | Leukocytes - physiology | Lymphokines - biosynthesis | Interleukin-2 - biosynthesis | Lymph Nodes - cytology
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15. The T-cell receptor problem
by Krammer, P.H
Current Topics in Microbiology and Immunology, ISSN 0070-217X, 1981, Volume 91, pp. 179 - 215
Immunoglobulin Light Chains - immunology | Major Histocompatibility Complex | Receptors, Antigen, T-Cell - metabolism | Lymphokines - physiology | Immunoglobulin Variable Region - immunology | Isoantigens - analysis | Interleukin-5 | Immunoglobulin Idiotypes - analysis | Interleukin-2 - physiology | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Immunity, Cellular | Immunoglobulin Heavy Chains - immunology
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16. Full Text Do OKT 3 monoclonal antibodies inhibit T-cell proliferation by blocking the receptor for TCGF?
by Lea, Tor
Immunology Letters, ISSN 0165-2478, 1982, Volume 5, Issue 6, pp. 311 - 315
OKT 3 monoclonal antibodies strongly inhibit the proliferation of T-cell growth factor (TCGF)-dependent continuously-growing T-lymphoblasts. The inhibition was... 
OKT 3 monoclonal antibodies | receptors for T-cell growth factor | T-cell antigen receptors | T-cell growth factor (TCGF) | human T-cell differentiation antigen | T-cell activation | IMMUNOLOGY | Binding, Competitive | Dose-Response Relationship, Immunologic | T-Lymphocytes - metabolism | Lymphocyte Activation | Humans | Antibodies, Monoclonal - physiology | T-Lymphocytes - immunology | Receptors, Immunologic - analysis | Receptors, Interleukin-2
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17. REGULATION OF THE IMMUNE-RESPONSE - T-CELL INTERACTIONS
by DUTTON, RW and SWAIN, SL
CRC CRITICAL REVIEWS IN IMMUNOLOGY, ISSN 0197-3355, 1982, Volume 3, Issue 3, pp. 209 - 261
IMMUNOLOGY | Interleukin-1 | Protein Biosynthesis | Mice, Inbred A | Antigens, Ly - genetics | Receptors, Antigen, T-Cell | T-Lymphocytes - classification | T-Lymphocytes, Regulatory - immunology | Interleukin-2 - physiology | Lymphocyte Cooperation | Thy-1 Antigens | Mice, Inbred CBA | Mice, Inbred DBA | Macrophages - immunology | Proteins - physiology | Major Histocompatibility Complex | Lymphocyte Activation | Mice, Inbred C57BL | Antigens, Surface - genetics | Cell Communication | Epitopes | Mice, Inbred C3H | Proteins - immunology | Animals | Protein Conformation | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Histocompatibility Antigens Class II - genetics | Interleukin-2 - biosynthesis | Immunity, Cellular | Mice, Inbred AKR
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