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Diabetes, Obesity and Metabolism, ISSN 1462-8902, 05/2017, Volume 19, Issue 5, pp. 682 - 694
Aims: Islet amyloid, formed by aggregation of human islet amyloid polypeptide (hIAPP), contributes to beta-cell failure in type 2 diabetes, cultured and... 
islet amyloid polypeptide | β‐cell apoptosis | type 2 diabetes | islet inflammation | interleukin‐1β | amylin | islet transplantation | islet amyloid | β-cell apoptosis | interleukin-1β | APOPTOSIS | HUMAN PANCREATIC-ISLETS | MECHANISM | DEPOSITION | AUTOPHAGY | beta-cell apoptosis | interleukin-1 beta | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | IL-1-BETA | EXPRESSION | CONTRIBUTES | POLYPEPTIDE | Humans | Middle Aged | Interleukin 1 Receptor Antagonist Protein - genetics | Islet Amyloid Polypeptide - genetics | Amyloid - chemistry | Diabetes Mellitus, Type 2 - metabolism | Interleukin-1beta - genetics | fas Receptor - metabolism | Protein Precursors - antagonists & inhibitors | Amyloid - metabolism | RNA Interference | Interleukin-1beta - metabolism | Islets of Langerhans - metabolism | Islets of Langerhans Transplantation - adverse effects | Interleukin 1 Receptor Antagonist Protein - metabolism | Islets of Langerhans - cytology | Adult | Insulin Secretion | Diabetes Mellitus, Type 2 - surgery | Interleukin-1beta - antagonists & inhibitors | Recombinant Proteins - metabolism | Amyloid - agonists | Amyloid - antagonists & inhibitors | Protein Precursors - genetics | Islets of Langerhans - pathology | Tissue Culture Techniques | Mice, Inbred C57BL | Islet Amyloid Polypeptide - metabolism | Mice, Transgenic | Islet Amyloid Polypeptide - antagonists & inhibitors | Hemizygote | Protein Precursors - metabolism | fas Receptor - agonists | Insulin - metabolism | Animals | Islet Amyloid Polypeptide - chemistry | Protein Processing, Post-Translational | Diabetes Mellitus, Type 2 - pathology | Cadaver | Apoptosis | Index Medicus
Journal Article
Neuropharmacology, ISSN 0028-3908, 06/2017, Volume 119, pp. 170 - 181
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 2017, Volume 56, Issue 3, pp. 1087 - 1099
Journal Article
Journal Article
Biological Psychiatry, ISSN 0006-3223, 12/2017, Volume 82, Issue 11, pp. 828 - 838
The pancreatic- and brain-derived hormone amylin promotes negative energy balance and is receiving increasing attention as a promising obesity therapeutic.... 
Obesity | IAPP | Reward | Food intake | Calcitonin | Motivated behavior | PSYCHIATRY | FOOD-INTAKE | MECHANISMS | NEUROSCIENCES | BODY-WEIGHT | MESSENGER-RNAS | AREA POSTREMA NUCLEUS | NEURONS | RAT-BRAIN | CALCITONIN RECEPTORS | PEPTIDE CGRP | Calcitonin - pharmacology | RNA, Small Interfering - genetics | Amylin Receptor Agonists - therapeutic use | gamma-Aminobutyric Acid - metabolism | Receptors, Islet Amyloid Polypeptide - antagonists & inhibitors | Body Weight - drug effects | Conditioning, Operant - physiology | Male | Peptide Fragments - pharmacology | Phosphopyruvate Hydratase - metabolism | Motivation - drug effects | Conditioning, Operant - drug effects | Receptors, Islet Amyloid Polypeptide - metabolism | Receptor Activity-Modifying Proteins - metabolism | Ventral Tegmental Area - drug effects | Food Preferences - drug effects | Rats | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | Eating - drug effects | GABA Agents - pharmacology | Animals | Islet Amyloid Polypeptide - pharmacology | Receptors, Islet Amyloid Polypeptide - genetics | Signal Transduction - drug effects | Receptor Activity-Modifying Proteins - genetics | Signal Transduction - physiology | Body Weight - physiology | RNA, Small Interfering - metabolism | GABA | Medical colleges | Evolutionary biology | Neurophysiology | Animal experimentation | Neurosciences | Neurons | Analysis | Index Medicus
Journal Article
by Fan, R and Li, X and Gu, X and Chan, J.C.N and Xu, G
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 09/2010, Volume 12, Issue 9, pp. 815 - 824
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 08/2013, Volume 38, Issue 9, pp. 1685 - 1697
Journal Article