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Journal of Hepatology, ISSN 0168-8278, 2006, Volume 46, Issue 3, pp. 411 - 419
.... Methods Expression and activity of LDLR were assessed by RT-PCR and LDL entry, in the absence or presence of squalestatin or 25-hydroxycholesterol that up- or down-regulates LDLR expression, respectively... 
Gastroenterology and Hepatology | Virus receptor | Genome replication | Virus entry | LDL RECEPTOR | CULTURED HUMAN HEPATOCYTES | IN-VITRO INFECTION | virus receptor | genome replication | CANDIDATE RECEPTOR | SCAVENGER RECEPTOR | HUMAN HEPATOMA-CELLS | STRUCTURAL PROTEINS | virus entry | TERM PRIMARY CULTURES | BINDING-SITE | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | CD18 Antigens - physiology | Humans | Middle Aged | Hepacivirus - genetics | Lipoproteins, LDL - physiology | Hepacivirus - pathogenicity | Hepatocytes - pathology | Male | Antibodies - physiology | Scavenger Receptors, Class B - physiology | Viral Load | RNA, Viral - genetics | Virion | Adult | Female | Hepacivirus - physiology | RNA, Viral - metabolism | Receptors, LDL - genetics | Tricarboxylic Acids - pharmacology | Cells, Cultured | Receptors, LDL - immunology | Hydroxycholesterols - pharmacology | Lipoproteins, HDL - physiology | Gene Expression Regulation - drug effects | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Adolescent | Hepatocytes - virology | Hepatitis C - physiopathology | Aged | Hepatitis C - pathology | Receptors, LDL - physiology | Anticholesteremic Agents - pharmacology | Hepatitis C | Health aspects | Scavenger Receptors, Class B | Receptors, LDL | Antibodies | Bicyclo Compounds, Heterocyclic | Life Sciences | Tricarboxylic Acids | Anticholesteremic Agents | Hépatology and Gastroenterology | Gene Expression Regulation | Human health and pathology | Hepatocytes | Hydroxycholesterols | RNA, Viral | Antigens, CD18 | Lipoproteins, HDL | Hepacivirus | Lipoproteins, LDL
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2004, Volume 279, Issue 47, pp. 48865 - 48875
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1262 - 1270
... with early type 2 diabetes is typically characterized by increased VLDL secretion but normal LDL cholesterol levels... 
NONHUMAN-PRIMATES | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | TARGET GENES | ACTIVATION | PLASMA-CHOLESTEROL | DIABETIC DYSLIPIDEMIA | INSULIN-RESISTANCE | LIVER | TRANSPLANT RECIPIENTS | UP-REGULATION | Liver Transplantation | Insulin - physiology | Multiprotein Complexes | Serine Endopeptidases - physiology | Hepatocyte Nuclear Factor 4 - physiology | Mechanistic Target of Rapamycin Complex 1 | RNA Interference | Insulin Resistance - physiology | Receptor, Insulin - genetics | Serine Endopeptidases - genetics | Hyperinsulinism - genetics | Proprotein Convertases | Postoperative Complications | Hyperinsulinism - metabolism | Proteins - physiology | Receptors, LDL - genetics | Serine Endopeptidases - deficiency | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Proto-Oncogene Proteins c-akt - physiology | Receptor, Insulin - physiology | Receptor, Insulin - antagonists & inhibitors | Sirolimus - pharmacology | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Receptors, LDL - biosynthesis | Mice, Obese | Mice | TOR Serine-Threonine Kinases | Hepatocyte Nuclear Factor 1-alpha - physiology | Proteins - antagonists & inhibitors | Proprotein Convertase 9 | Measurement | Liver | Physiological aspects | Low density lipoprotein receptors | Cellular signal transduction | Research | Properties | Insulin | Health aspects
Journal Article
Cell, ISSN 0092-8674, 11/2001, Volume 107, Issue 4, pp. 513 - 523
In humans, low peak bone mass is a significant risk factor for osteoporosis. We report that LRP5, encoding the low-density lipoprotein receptor-related protein... 
MINERAL DENSITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | OSTEOBLAST LINEAGE | MOLECULAR-CLONING | MICE | DIFFERENTIATION | BETA-CATENIN | OSTEOPOROSIS | CELL-DEATH | FAMILY | CELL BIOLOGY | Wnt2 Protein | Humans | Child, Preschool | Male | Bone Density - genetics | Wnt Proteins | Mesoderm - cytology | Wnt-5a Protein | Eye - embryology | Osteoporosis - genetics | Animals, Outbred Strains | Dishevelled Proteins | Bone Morphogenetic Proteins - pharmacology | Child | Organ Culture Techniques | Transforming Growth Factor beta | Signal Transduction | Chromosomes, Human, Pair 11 - genetics | Adaptor Proteins, Signal Transducing | Skull - cytology | Wnt3 Protein | Mice | Receptors, LDL - physiology | COS Cells | Species Specificity | LDL-Receptor Related Proteins | DNA, Complementary - genetics | Recombinant Fusion Proteins - physiology | Cercopithecus aethiops | Culture Media, Conditioned - pharmacology | Recombinant Proteins | Transfection | Receptors, LDL - deficiency | Stromal Cells - drug effects | Adult | Female | Phosphoproteins - physiology | Proteins - physiology | Receptors, LDL - genetics | Bone Morphogenetic Protein 2 | Low Density Lipoprotein Receptor-Related Protein-5 | Mice, Inbred C57BL | Zebrafish Proteins | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Eye Abnormalities - genetics | Genes, Recessive | Syndrome | Proteins - genetics | Animals | Proto-Oncogene Proteins - physiology | Heterozygote | Osteoblasts - metabolism | Stromal Cells - cytology | Wnt4 Protein | Osteoporosis | Bones | Density | Low density lipoproteins | Proteins | Cell research | Lipoproteins | Growth | Analysis | Physiological aspects | Receptors, LDL | Mesoderm | Osteoblasts | Recombinant Fusion Proteins | Eye | Life Sciences | Stromal Cells | Eye Abnormalities | Phosphoproteins | Proto-Oncogene Proteins | Bone Density | Biochemistry, Molecular Biology | Culture Media, Conditioned | Skull | Chromosomes, Human, Pair 11 | Bone Morphogenetic Proteins | DNA, Complementary
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 01/2016, Volume 136, Issue 2, pp. 306 - 315
Journal Article
Circulation Research, ISSN 0009-7330, 02/2015, Volume 116, Issue 5, pp. 789 - 796
RATIONALE:Noncoding gene variants at the SORT1 locus are strongly associated with low-density lipoprotein cholesterol (LDL-C... 
Foam cell | Receptor-mediated endocytosis | Low-density lipoprotein cholesterol | Atherosclerosis | Macrophage | atherosclerosis | FAMILIAL HYPERCHOLESTEROLEMIA | CARDIAC & CARDIOVASCULAR SYSTEMS | CHOLESTEROL | VARIANTS | low-density lipoprotein cholesterol | PROSAPOSIN | macrophage | LOCI | HYPERLIPIDEMIC MICE | MOUSE MODELS | receptor-mediated endocytosis | COMPLEXITY | foam cell | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | ASSOCIATION | CORONARY-ARTERY-DISEASE | Atherosclerosis - genetics | Adaptor Proteins, Vesicular Transport - deficiency | Adaptor Proteins, Vesicular Transport - genetics | Male | Aortic Diseases - metabolism | Atherosclerosis - etiology | APOBEC-1 Deaminase | Receptors, LDL - deficiency | Aortic Diseases - prevention & control | Cholesterol, LDL - blood | Female | Lipoproteins, LDL - metabolism | Foam Cells - metabolism | Receptors, LDL - genetics | Adaptor Proteins, Vesicular Transport - physiology | Cytidine Deaminase - genetics | Mice, Transgenic | Radiation Chimera | Diet, Western - adverse effects | Atherosclerosis - metabolism | Mice, Knockout | Aortic Diseases - genetics | Macrophages - metabolism | Animals | Mice | Receptors, LDL - physiology | Macrophages, Peritoneal - metabolism | Aortic Diseases - etiology | Atherosclerosis - prevention & control | Bone Marrow Cells - metabolism | low density lipoprotein cholesterol
Journal Article
Circulation Research, ISSN 0009-7330, 11/2005, Volume 97, Issue 11, pp. 1190 - 1197
Journal Article
Journal Article