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animals (639) 639
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receptors, lysosphingolipid - metabolism (489) 489
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mice (323) 323
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fty720 (143) 143
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Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2012, Volume 335, Issue 6070, pp. 851 - 855
Journal Article
Biochemical journal, ISSN 0264-6021, 2013, Volume 449, Issue 3, pp. 661 - 672
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2006, Volume 2, Issue 8, pp. 434 - 441
Journal Article
Critical Reviews in Biochemistry and Molecular Biology, ISSN 1040-9238, 07/2015, Volume 50, Issue 4, pp. 298 - 313
Journal Article
Journal Article
BioFactors (Oxford), ISSN 0951-6433, 2012, Volume 38, Issue 5, pp. 329 - 337
Sphingosine‐1‐phosphate (S1P), which acts as both the extracellular and intracellular messenger, exerts pleiotropic biological activities including regulation... 
lysophospholipid | G protein‐coupled receptor | sphingosine‐1‐phosphate | G protein-coupled receptor | Lysophospholipid | Sphingosine-1-phosphate | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR ANGIOGENESIS | LYMPHOCYTE EGRESS | SPHINGOSINE 1-PHOSPHATE | S1P | INHIBITION | PROTEIN-COUPLED RECEPTOR | CELL-MIGRATION | IN-VIVO | ENDOCRINOLOGY & METABOLISM | sphingosine-1-phosphate | MICE | LYASE | Lysophospholipids - metabolism | Receptors, Lysosphingolipid - antagonists & inhibitors | Cell Proliferation | Humans | rac GTP-Binding Proteins - metabolism | rho-Associated Kinases - genetics | NF-kappa B - metabolism | Biological Products - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Chemotaxis | Proto-Oncogene Proteins c-akt - genetics | Gene Expression Regulation - drug effects | Phosphatidylinositol 3-Kinases - genetics | Sphingosine - analogs & derivatives | NF-kappa B - genetics | Signal Transduction - drug effects | rho-Associated Kinases - metabolism | rac GTP-Binding Proteins - genetics | Receptors, Lysosphingolipid - agonists | Receptors, Lysosphingolipid - genetics | Sphingosine - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptors, Lysosphingolipid - metabolism | Biological Products - therapeutic use | Phosphates | Drugs | Enzymes | Drug delivery systems | Lymphocytes | Sphingosine | Physiological aspects | G proteins | Gene expression | Cells | Membrane proteins | Vehicles
Journal Article
PLoS Biology, ISSN 1544-9173, 01/2014, Volume 12, Issue 1, p. e1001763
Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and... 
SMOOTH-MUSCLE | HORIZONTAL CONNECTIONS | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | BIOLOGY | AXONAL REGENERATION | LONG-TERM POTENTIATION | SPHINGOSINE-1-PHOSPHATE RECEPTORS | RAT MOTOR CORTEX | MICROSCALE THERMOPHORESIS | SPHINGOSINE 1-PHOSPHATE | Lysophospholipids - metabolism | Receptors, Lysosphingolipid - antagonists & inhibitors | Cell Proliferation | Myelin Proteins - deficiency | Proprotein Convertases - genetics | GTP-Binding Protein alpha Subunits, G12-G13 - metabolism | Myelin Sheath - metabolism | Neuronal Plasticity - genetics | Motor Cortex - metabolism | Synapses - metabolism | Serine Endopeptidases - genetics | Receptors, Lysosphingolipid - genetics | Nogo Proteins | Sphingosine - metabolism | Receptors, Lysosphingolipid - metabolism | Signal Transduction | rho GTP-Binding Proteins - genetics | Proprotein Convertases - metabolism | GTP-Binding Protein alpha Subunits, G12-G13 - genetics | Gene Expression Regulation | Neurites - metabolism | Hippocampus - cytology | Myelin Proteins - genetics | Mice, Knockout | Hippocampus - metabolism | Sphingosine - analogs & derivatives | Animals | Myelin Sheath - genetics | rho GTP-Binding Proteins - metabolism | Long-Term Potentiation | Mice | Serine Endopeptidases - metabolism | Motor Cortex - cytology | Neuroplasticity | Physiological aspects | Sphingolipids | Research | Neurological research | Proteins | Medical research | Spinal cord | Colleges & universities | Nervous system | Ligands | Kinases | Experiments | Molecular weight
Journal Article
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2018, Volume 28, Issue 23-24, pp. 3585 - 3591
[Display omitted] Sphingolipids represent an essential class of lipids found in all eukaryotes, and strongly influence cellular signal transduction. Autoimmune... 
S1P1 agonists | Sphingolipids | Sphingosine-1-phosphate receptor 1 | Sphingosine-1-phosphate | Autoimmune modulators | S1P | agonists | S1P AGONIST | S1P agonists | CHEMISTRY, MEDICINAL | ANALOG AAL-R | ORAL FINGOLIMOD FTY720 | CHEMISTRY, ORGANIC | LYMPHOCYTE EGRESS | IMMUNOMODULATORY DRUG FTY720 | SPHINGOSINE 1-PHOSPHATE RECEPTOR-1 | REMITTING MULTIPLE-SCLEROSIS | PROTEIN-COUPLED RECEPTOR | BIOLOGICAL EVALUATION | SELECTIVE AGONIST | Receptors, Lysosphingolipid - antagonists & inhibitors | Humans | Immunosuppressive Agents - pharmacokinetics | Immunosuppressive Agents - therapeutic use | Biological Availability | Sphingolipids - metabolism | Oxadiazoles - therapeutic use | Fingolimod Hydrochloride - chemistry | Multiple Sclerosis - pathology | Receptors, Lysosphingolipid - agonists | Oxadiazoles - chemistry | Oxadiazoles - pharmacokinetics | Receptors, Lysosphingolipid - metabolism | Autoimmune Diseases - metabolism | Autoimmune Diseases - pathology | Autoimmune Diseases - drug therapy | Fingolimod Hydrochloride - pharmacokinetics | Fingolimod Hydrochloride - therapeutic use | Immunosuppressive Agents - chemistry | Multiple Sclerosis - drug therapy | Multiple Sclerosis - metabolism | Phosphates | Multiple sclerosis | Sphingosine | Physiological aspects | Lipids | Cellular signal transduction | G proteins | Epidemiology | Membrane proteins
Journal Article